ChR2 mutants at L132 and T159 with improved operational light sensitivity for vision restoration

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Pan, Zhuo Hua ^a,b   Ganjawala, Tushar H ^a   Lu, Qi ^a   Ivanova, Elena ^a,c   Zhang, Zhifei ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHANNELRHODOPSIN 2; LEUCINE; SENSORY RHODOPSIN; THREONINE; UNCLASSIFIED DRUG; CHANNELRHODOPSIN 2, HUMAN; RHODOPSIN;

ADULT; AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL ACTIVITY; CONVALESCENCE; CORRELATIONAL STUDY; EMBRYO CELL; HUMAN; HUMAN CELL; KIDNEY CELL; LIGHT ADAPTATION; LIGHT INTENSITY; LIGHT RELATED PHENOMENA; MOUSE; MUTANT; NONHUMAN; OPERATIONAL LIGHT SENSITIVITY; OPTOGENETICS; PHOTOREACTIVITY; PHOTOSTIMULATION; RETINA GANGLION CELL; VISION; VISUAL ACUITY; WILD TYPE; ACTION POTENTIAL; ANIMAL; GENE EXPRESSION; GENETIC TRANSDUCTION; GENETICS; HEK293 CELL LINE; METABOLISM; MUTATION; PATHOPHYSIOLOGY; RETINA DEGENERATION;

ACTION POTENTIALS; ANIMALS; GENE EXPRESSION; HEK293 CELLS; HUMANS; MICE; MUTATION; RETINAL DEGENERATION; RETINAL GANGLION CELLS; RHODOPSIN; TRANSDUCTION, GENETIC; VISION, OCULAR;

EID: 84902440395     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098924     Document Type: Article

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