Channelrhodopsin-2 is a leaky proton pump

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 30, 2009, Pages 12317-12322

  Feldbauer, Katrin ^a   Zimmermann, Dirk ^a   Pintschovius, Verena ^a   Spitz, Julia ^a   Bamann, Christian ^a   Bamberg, Ernst ^a,b  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Ion transport; Light driven pump; Light gated channel; Noise analysis

Indexed keywords

BACTERIORHODOPSIN; CATION; CHANNELRHODOPSIN 2; ESSENTIAL AMINO ACID; HELIX LOOP HELIX PROTEIN; HYDROGEN; ION CHANNEL; PROTON PUMP; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; HUMAN; HUMAN CELL; KINETICS; LIPID BILAYER; MOLECULAR MECHANICS; NOISE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; SPECTROSCOPY; VOLTAGE CLAMP;

CARRIER PROTEINS; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINE; HUMANS; ION CHANNELS; KINETICS; LIGHT; MEMBRANE POTENTIALS; PATCH-CLAMP TECHNIQUES; PROTON PUMPS; SODIUM CHLORIDE; TEMPERATURE; TRANSFECTION;

ANIMALIA;

EID: 68149145775     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0905852106     Document Type: Article

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