Direct interaction of CD40 on tumor cells with CD40L on T cells increases the proliferation of tumor cells by enhancing TGF-β production and Th17 differentiation

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Kim, Hyemin ^a   Kim, Yejin ^a   Bae, Seyeon ^a   Kong, Joo Myoung ^a   Choi, Jiwon ^a   Jang, Mirim ^a   Choi, Jiyea ^a   Hong, Jun Man ^a   Hwang, Young Il ^a   Kang, Jae Seung ^a   Lee, Wang Jae ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 21; INTERLEUKIN 6; RETINOID RELATED ORPHAN RECEPTOR GAMMA; STAT3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; MESSENGER RNA; RNA; SMALL INTERFERING RNA; STAT3 PROTEIN, HUMAN;

ANTIGEN BINDING; ANTIGEN EXPRESSION; ANTIGEN FUNCTION; ARTICLE; BREAST CANCER CELL LINE; CELL DIFFERENTIATION; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TH17 CELL; TUMOR GROWTH; UPREGULATION; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BREAST TUMOR; COCULTURE; FEMALE; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ANTIGENS, CD40; BREAST NEOPLASMS; CD40 LIGAND; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; COCULTURE TECHNIQUES; FEMALE; HUMANS; INTERLEUKIN-17; LYMPHOCYTE ACTIVATION; RNA, MESSENGER; RNA, NEOPLASM; RNA, SMALL INTERFERING; STAT3 TRANSCRIPTION FACTOR; T-LYMPHOCYTES; TH17 CELLS; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 84930628095     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125742     Document Type: Article

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