Docking analysis insights quercetin can be a non-antibiotic adjuvant by inhibiting Mmr drug efflux pump in Mycobacterium sp. and its homologue EmrE in Escherichia coli

Journal of Biomolecular Structure and Dynamics

Volumn 33, Issue 8, 2015, Pages 1819-1834

  Suriyanarayanan, Balasubramanian ^a   Santhosh, Ramachandran Sarojini ^a  

^a SASTRA UNIVERSITY   (India)

Author keywords

efflux pump; Mycobacterium smegmatis; Mycobacterium tuberculosis; quercetin

Indexed keywords

BACTERIAL PROTEIN; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CHLORPROMAZINE; PROTEIN EMRE; PROTEIN MMR; QUERCETIN; RESERPINE; UNCLASSIFIED DRUG; VERAPAMIL; ANTIPORTER; CARRIER PROTEIN; EMRE PROTEIN, E COLI; ESCHERICHIA COLI PROTEIN; LIGAND; PROTEIN BINDING;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ESCHERICHIA COLI; HYDROPHOBICITY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; SIMULATION; STATIC ELECTRICITY; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; HYDROGEN BOND; MYCOBACTERIUM; PROTEIN MULTIMERIZATION; QUANTITATIVE STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM SP.; MYCOBACTERIUM TUBERCULOSIS;

ANTIPORTERS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROGEN BONDING; LIGANDS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MYCOBACTERIUM; PROTEIN BINDING; PROTEIN MULTIMERIZATION; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; QUERCETIN;

EID: 84930571421     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2014.974211     Document Type: Article

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