Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: Membrane topology and identification of residues involved in substrate specificity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3630-3635

  Paulsen, I T ^a,b,c   Brown, M H ^a   Littlejohn, T G ^a,b   Mitchell, B A ^a   Skurray, R A ^a,b  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Department of Microbiology ^*  (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

drug efflux pumps; major facilitator superfamily; protein topology

Indexed keywords

ALKALINE PHOSPHATASE; BETA GALACTOSIDASE; DIVALENT CATION; HYDROXYLAMINE; MULTIDRUG RESISTANCE PROTEIN QAC A; MULTIDRUG RESISTANCE PROTEIN QAC B; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ENZYME SPECIFICITY; ESCHERICHIA COLI; MULTIDRUG RESISTANCE; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; STAPHYLOCOCCUS AUREUS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CLONING, MOLECULAR; DNA PRIMERS; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE; MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTAGENESIS, SITE-DIRECTED; STAPHYLOCOCCUS AUREUS; SUBSTRATE SPECIFICITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; STAPHYLOCOCCUS AUREUS;

EID: 0029872148     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3630     Document Type: Article

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