-
2
-
-
0034284970
-
Bone resorption by osteoclasts
-
Teitelbaum SL. Bone resorption by osteoclasts. Science. 2000; 289(5484):1504-1508.
-
(2000)
Science
, vol.289
, Issue.5484
, pp. 1504-1508
-
-
Teitelbaum, S.L.1
-
3
-
-
78650257620
-
Pparγ in bone homeostasis
-
Wan Y. PPARγ in bone homeostasis. Trends Endocrinol Metab. 2010;21(12):722-728.
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.12
, pp. 722-728
-
-
Wan, Y.1
-
4
-
-
36849034568
-
Ppar-γ regulates osteoclastogenesis in mice
-
Wan Y, Chong LW, Evans RM. PPAR-γ regulates osteoclastogenesis in mice. Nat Med. 2007;13(12):1496-1503.
-
(2007)
Nat Med
, vol.13
, Issue.12
, pp. 1496-1503
-
-
Wan, Y.1
Chong, L.W.2
Evans, R.M.3
-
5
-
-
0037673945
-
Osteoclast differentiation and activation
-
Boyle WJ, Simonet WS, Lacey DL. Osteoclast differentiation and activation. Nature. 2003;423(6937):337-342.
-
(2003)
Nature
, vol.423
, Issue.6937
, pp. 337-342
-
-
Boyle, W.J.1
Simonet, W.S.2
Lacey, D.L.3
-
7
-
-
33947532026
-
Histone acetyltransferase complexes: One size doesn’t fit all
-
Lee KK, Workman JL. Histone acetyltransferase complexes: one size doesn’t fit all. Nat Rev Mol Cell Biol. 2007;8(4):284-295.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, Issue.4
, pp. 284-295
-
-
Lee, K.K.1
Workman, J.L.2
-
8
-
-
0034650893
-
The coregulator exchange in transcriptional functions of nuclear receptors
-
Glass CK, Rosenfeld MG. The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 2000;14(2):121- 141.
-
(2000)
Genes Dev
, vol.14
, Issue.2
, pp. 121-141
-
-
Glass, C.K.1
Rosenfeld, M.G.2
-
9
-
-
1842578986
-
Molecular evolution of the histone deacetylase family: Functional implications of phylogenetic analysis
-
Gregoretti IV, Lee YM, Goodson HV. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol. 2004;338(1):17-31.
-
(2004)
J Mol Biol
, vol.338
, Issue.1
, pp. 17-31
-
-
Gregoretti, I.V.1
Lee, Y.M.2
Goodson, H.V.3
-
10
-
-
0036527775
-
Histone-deacetylase inhibitors: Novel drugs for the treatment of cancer
-
Johnstone RW. Histone-deacetylase inhibitors: novel drugs for the treatment of cancer. Nat Rev Drug Discov. 2002;1(4):287-299.
-
(2002)
Nat Rev Drug Discov
, vol.1
, Issue.4
, pp. 287-299
-
-
Johnstone, R.W.1
-
11
-
-
53249130741
-
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
-
Kazantsev AG, Thompson LM. Therapeutic application of histone deacetylase inhibitors for central nervous system disorders. Nat Rev Drug Discov. 2008;7(10):854-868.
-
(2008)
Nat Rev Drug Discov
, vol.7
, Issue.10
, pp. 854-868
-
-
Kazantsev, A.G.1
Thompson, L.M.2
-
12
-
-
79953330801
-
Hdac3 and hdac7 have opposite effects on osteoclast differentiation
-
Pham L, Kaiser B, Romsa A, et al. HDAC3 and HDAC7 have opposite effects on osteoclast differentiation. J Biol Chem. 2011; 286(14):12056-12065.
-
(2011)
J Biol Chem
, vol.286
, Issue.14
, pp. 12056-12065
-
-
Pham, L.1
Kaiser, B.2
Romsa, A.3
-
13
-
-
84873019253
-
Hdac7 inhibits osteoclastogenesis by reversing rankl-triggered β-catenin switch
-
Jin Z, Wei W, Dechow PC, Wan Y. HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch. Mol Endocrinol. 2013;27(2):325-335.
-
(2013)
Mol Endocrinol
, vol.27
, Issue.2
, pp. 325-335
-
-
Jin, Z.1
Wei, W.2
Dechow, P.C.3
Wan, Y.4
-
14
-
-
80051693245
-
Histone deacetylase 9 deficiency protects against effector t cellmediated systemic autoimmunity
-
Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N. Histone deacetylase 9 deficiency protects against effector T cellmediated systemic autoimmunity. J Biol Chem. 2011;286(33): 28833-28843.
-
(2011)
J Biol Chem
, vol.286
, Issue.33
, pp. 28833-28843
-
-
Yan, K.1
Cao, Q.2
Reilly, C.M.3
Young, N.L.4
Garcia, B.A.5
Mishra, N.6
-
15
-
-
84906938566
-
Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development
-
Cao Q, Rong S, Repa JJ, St Clair R, Parks JS, Mishra N. Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development. Arterioscler Thromb Vasc Biol. 2014;34(9):1871-1879.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, Issue.9
, pp. 1871-1879
-
-
Cao, Q.1
Rong, S.2
Repa, J.J.3
St Clair, R.4
Parks, J.S.5
Mishra, N.6
-
16
-
-
84891751641
-
Hdac9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding
-
Chatterjee TK, Basford JE, Knoll E, et al. HDAC9 knockout mice are protected from adipose tissue dysfunction and systemic metabolic disease during high-fat feeding. Diabetes. 2014;63(1):176- 187.
-
(2014)
Diabetes
, vol.63
, Issue.1
, pp. 176-187
-
-
Chatterjee, T.K.1
Basford, J.E.2
Knoll, E.3
-
17
-
-
79960972108
-
Histone deacetylase 9 is a negative regulator of adipogenic differentiation
-
Chatterjee TK, Idelman G, Blanco V, et al. Histone deacetylase 9 is a negative regulator of adipogenic differentiation. J Biol Chem. 2011;286(31):27836-27847.
-
(2011)
J Biol Chem
, vol.286
, Issue.31
, pp. 27836-27847
-
-
Chatterjee, T.K.1
Idelman, G.2
Blanco, V.3
-
18
-
-
84863393715
-
Wellcome trust case control consortium 2 (wtccc2), bellenguez c, et al. Ge nome-wide association study identifies a variant in hdac9 associated with large vessel ischemic stroke
-
International Stroke Genetics Consortium (ISGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Bellenguez C, et al. Ge nome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet. 2012;44(3): 328-333.
-
(2012)
Nat Genet
, vol.44
, Issue.3
, pp. 328-333
-
-
-
19
-
-
0037162697
-
Histone deacetylases act as signal-responsive repressors of cardiac hypertrophy
-
Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell. 2002;110(4):479-488.
-
(2002)
Cell
, vol.110
, Issue.4
, pp. 479-488
-
-
Zhang, C.L.1
McKinsey, T.A.2
Chang, S.3
Antos, C.L.4
Hill, J.A.5
Olson, E.N.6
Class, I.I.7
-
20
-
-
84907406375
-
Huynh h, et al. Mir-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and tgif2
-
Krzeszinski JY, Wei W, Huynh H, et al. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2. Nature. 2014;512(7515):431-435.
-
(2014)
Nature
, vol.512
, Issue.7515
, pp. 431-435
-
-
Krzeszinski, J.Y.1
Wei, W.2
-
21
-
-
84863116228
-
Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ
-
Wei W, Dutchak PA, Wang X, et al. Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ. Proc Natl Acad Sci USA. 2012; 109(8):3143-3148.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.8
, pp. 3143-3148
-
-
Wei, W.1
Dutchak, P.A.2
Wang, X.3
-
22
-
-
42749095897
-
Notch1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells
-
Bai S, Kopan R, Zou W, et al. NOTCH1 regulates osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblast lineage cells. J Biol Chem. 2008;283(10):6509-6518.
-
(2008)
J Biol Chem
, vol.283
, Issue.10
, pp. 6509-6518
-
-
Bai, S.1
Kopan, R.2
Zou, W.3
-
23
-
-
83255192191
-
Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin
-
Wei W, Zeve D, Suh JM, et al. Biphasic and dosage-dependent regulation of osteoclastogenesis by β-catenin. Mol Cell Biol. 2011; 31(23):4706-4719.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.23
, pp. 4706-4719
-
-
Wei, W.1
Zeve, D.2
Suh, J.M.3
-
24
-
-
33846139305
-
Regulation of HDAC9 gene expression by mef2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation
-
Haberland M, Arnold MA, McAnally J, Phan D, Kim Y, Olson EN. Regulation of HDAC9 gene expression by MEF2 establishes a negative-feedback loop in the transcriptional circuitry of muscle differentiation. Mol Cell Biol. 2007;27(2):518-525.
-
(2007)
Mol Cell Biol
, vol.27
, Issue.2
, pp. 518-525
-
-
Haberland, M.1
Arnold, M.A.2
McAnally, J.3
Phan, D.4
Kim, Y.5
Olson, E.N.6
-
25
-
-
83255186737
-
Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population
-
Wei W, Zeve D, Wang X, et al. Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population. Mol Cell Biol. 2011;31(23):4692-4705.
-
(2011)
Mol Cell Biol
, vol.31
, Issue.23
, pp. 4692-4705
-
-
Wei, W.1
Zeve, D.2
Wang, X.3
-
26
-
-
77956408841
-
Pgc1β mediates pparγ activation of osteoclastogenesis and rosiglitazone-induced bone loss
-
Wei W, Wang X, Yang M, et al. PGC1β mediates PPARγ activation of osteoclastogenesis and rosiglitazone-induced bone loss. Cell Metab. 2010;11(6):503-516.
-
(2010)
Cell Metab
, vol.11
, Issue.6
, pp. 503-516
-
-
Wei, W.1
Wang, X.2
Yang, M.3
-
27
-
-
84886633604
-
Novel approaches to anticonvulsant drug discovery
-
Miziak B, Chroscinska-Krawczyk M, Blaszczyk B, Radzik I, Czuczwar SJ. Novel approaches to anticonvulsant drug discovery. Expert Opin Drug Discov. 2013;8(11):1415-1427.
-
(2013)
Expert Opin Drug Discov
, vol.8
, Issue.11
, pp. 1415-1427
-
-
Miziak, B.1
Chroscinska-Krawczyk, M.2
Blaszczyk, B.3
Radzik, I.4
Czuczwar, S.J.5
-
28
-
-
33947228816
-
The sanad study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: An unblinded randomised controlled trial
-
Marson AG, Al-Kharusi AM, Alwaidh M, et al. The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial. Lancet. 2007;369(9566):1016-1026.
-
(2007)
Lancet
, vol.369
, Issue.9566
, pp. 1016-1026
-
-
Marson, A.G.1
Al-Kharusi, A.M.2
Alwaidh, M.3
-
29
-
-
34250810709
-
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (vorinostat, saha) profoundly inhibits the growth of human pancreatic cancer cells
-
Kumagai T, Wakimoto N, Yin D, et al. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. Int J Cancer. 2007;121(3):656-665.
-
(2007)
Int J Cancer
, vol.121
, Issue.3
, pp. 656-665
-
-
Kumagai, T.1
Wakimoto, N.2
Yin, D.3
-
30
-
-
34547683194
-
Phase iib multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous t-cell lymphoma
-
Olsen EA, Kim YH, Kuzel TM, et al. Phase IIb multicenter trial of vorinostat in patients with persistent, progressive, or treatment refractory cutaneous T-cell lymphoma. J Clin Oncol. 2007;25(21): 3109-3115.
-
(2007)
J Clin Oncol
, vol.25
, Issue.21
, pp. 3109-3115
-
-
Olsen, E.A.1
Kim, Y.H.2
Kuzel, T.M.3
-
31
-
-
33845996135
-
Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, saha) for refractory cutaneous t-cell lymphoma (ctcl)
-
Duvic M, Talpur R, Ni X, et al. Phase 2 trial of oral vorinostat (suberoylanilide hydroxamic acid, SAHA) for refractory cutaneous T-cell lymphoma (CTCL). Blood. 2007;109(1):31-39.
-
(2007)
Blood
, vol.109
, Issue.1
, pp. 31-39
-
-
Duvic, M.1
Talpur, R.2
Ni, X.3
-
32
-
-
33644836549
-
Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies
-
O’Connor OA, Heaney ML, Schwartz L, et al. Clinical experience with intravenous and oral formulations of the novel histone deacetylase inhibitor suberoylanilide hydroxamic acid in patients with advanced hematologic malignancies. J Clin Oncol. 2006; 24(1):166-173.
-
(2006)
J Clin Oncol
, vol.24
, Issue.1
, pp. 166-173
-
-
O’Connor, O.A.1
Heaney, M.L.2
Schwartz, L.3
-
33
-
-
1842786823
-
The effect of valproate on bone mineral density in adult epileptic patients
-
Boluk A, Guzelipek M, Savli H, Temel I, Ozisik HI, Kaygusuz A. The effect of valproate on bone mineral density in adult epileptic patients. Pharmacol Res. 2004;50(1):93-97.
-
(2004)
Pharmacol Res
, vol.50
, Issue.1
, pp. 93-97
-
-
Boluk, A.1
Guzelipek, M.2
Savli, H.3
Temel, I.4
Ozisik, H.I.5
Kaygusuz, A.6
-
34
-
-
7944235860
-
Fracture risk associated with use of antiepileptic drugs
-
Vestergaard P, Rejnmark L, Mosekilde L. Fracture risk associated with use of antiepileptic drugs. Epilepsia. 2004;45(11):1330-1337.
-
(2004)
Epilepsia
, vol.45
, Issue.11
, pp. 1330-1337
-
-
Vestergaard, P.1
Rejnmark, L.2
Mosekilde, L.3
-
35
-
-
28144448363
-
Histone deacetylase inhibitors promote osteoblast maturation
-
Schroeder TM, Westendorf JJ. Histone deacetylase inhibitors promote osteoblast maturation. J Bone Miner Res. 2005;20(12):2254- 2263.
-
(2005)
J Bone Miner Res
, vol.20
, Issue.12
, pp. 2254-2263
-
-
Schroeder, T.M.1
Westendorf, J.J.2
-
36
-
-
0038542837
-
Two histone deacetylase inhibitors, trichostatin a and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages
-
Rahman MM, Kukita A, Kukita T, Shobuike T, Nakamura T, Kohashi O. Two histone deacetylase inhibitors, trichostatin A and sodium butyrate, suppress differentiation into osteoclasts but not into macrophages. Blood. 2003;101(9):3451-3459.
-
(2003)
Blood
, vol.101
, Issue.9
, pp. 3451-3459
-
-
Rahman, M.M.1
Kukita, A.2
Kukita, T.3
Shobuike, T.4
Nakamura, T.5
Kohashi, O.6
|