메뉴 건너뛰기




Volumn 56, Issue 2, 2015, Pages 519-527

C-Reactive Protein Induces Tau Hyperphosphorylation via GSK3β Signaling Pathway in SH-SY5Y Cells

Author keywords

Alzheimer s disease (AD); C reactive protein (CRP); Glycogen synthase kinase 3 beta (GSK3 ); Neurofibrillary tangles (NFTs); Tau

Indexed keywords

2 (2,4 DICHLOROPHENYL) 3 (1 METHYL 3 INDOLYL)MALEIMIDE; C REACTIVE PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN KINASE B; TAU PROTEIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MITOGEN ACTIVATED PROTEIN KINASE P38;

EID: 84930482724     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-015-0572-z     Document Type: Article
Times cited : (9)

References (38)
  • 1
    • 33845459140 scopus 로고    scopus 로고
    • Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer’s brain
    • COI: 1:CAS:528:DC%2BD2sXpslU%3D, PID: 17151277
    • Abad MA, Enguita M, DeGregorio-Rocasolano N, Ferrer I, Trullas R (2006) Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer’s brain. J Neurosci 26:12735–12747
    • (2006) J Neurosci , vol.26 , pp. 12735-12747
    • Abad, M.A.1    Enguita, M.2    DeGregorio-Rocasolano, N.3    Ferrer, I.4    Trullas, R.5
  • 2
    • 3343005434 scopus 로고    scopus 로고
    • PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations
    • COI: 1:CAS:528:DC%2BD2cXlsVWgt7Y%3D, PID: 15192701
    • Baki L, Shioi J, Wen P, Shao Z, Schwarzman A, Gama-Sosa M, Neve R, Robakis NK (2004) PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations. EMBO J 23:2586–2596
    • (2004) EMBO J , vol.23 , pp. 2586-2596
    • Baki, L.1    Shioi, J.2    Wen, P.3    Shao, Z.4    Schwarzman, A.5    Gama-Sosa, M.6    Neve, R.7    Robakis, N.K.8
  • 4
    • 84862804934 scopus 로고    scopus 로고
    • Promotion of beta-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC38XjtVOhsbw%3D, PID: 22202667
    • Bi BT, Lin HB, Cheng YF, Zhou H, Lin T, Zhang MZ, Li TJ, Xu JP (2012) Promotion of beta-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer’s disease. Neurochem Int 60:257–266
    • (2012) Neurochem Int , vol.60 , pp. 257-266
    • Bi, B.T.1    Lin, H.B.2    Cheng, Y.F.3    Zhou, H.4    Lin, T.5    Zhang, M.Z.6    Li, T.J.7    Xu, J.P.8
  • 5
    • 84899019792 scopus 로고    scopus 로고
    • Amyloid-beta and tau: the trigger and bullet in Alzheimer disease pathogenesis
    • PID: 24493463
    • Bloom GS (2014) Amyloid-beta and tau: the trigger and bullet in Alzheimer disease pathogenesis. JAMA Neurol 71:505–508
    • (2014) JAMA Neurol , vol.71 , pp. 505-508
    • Bloom, G.S.1
  • 7
    • 0346492847 scopus 로고    scopus 로고
    • Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells
    • COI: 1:CAS:528:DC%2BD3sXpvF2qtr8%3D, PID: 14698355
    • Datki Z, Juhasz A, Galfi M, Soos K, Papp R, Zadori D, Penke B (2003) Method for measuring neurotoxicity of aggregating polypeptides with the MTT assay on differentiated neuroblastoma cells. Brain Res Bull 62:223–229
    • (2003) Brain Res Bull , vol.62 , pp. 223-229
    • Datki, Z.1    Juhasz, A.2    Galfi, M.3    Soos, K.4    Papp, R.5    Zadori, D.6    Penke, B.7
  • 8
    • 84895513254 scopus 로고    scopus 로고
    • Pentraxins: structure, function, and role in inflammation
    • PID: 24167754
    • Du Clos TW (2013) Pentraxins: structure, function, and role in inflammation. ISRN Inflamm 2013:379040
    • (2013) ISRN Inflamm , vol.2013 , pp. 379040
    • Du Clos, T.W.1
  • 9
    • 0031017154 scopus 로고    scopus 로고
    • C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer’s disease
    • COI: 1:CAS:528:DyaK2sXpt12iuw%3D%3D, PID: 9070642
    • Duong T, Nikolaeva M, Acton PJ (1997) C-reactive protein-like immunoreactivity in the neurofibrillary tangles of Alzheimer’s disease. Brain Res 749:152–156
    • (1997) Brain Res , vol.749 , pp. 152-156
    • Duong, T.1    Nikolaeva, M.2    Acton, P.J.3
  • 10
    • 76549104226 scopus 로고    scopus 로고
    • Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3cXks1Kjtrs%3D, PID: 20160456
    • Eikelenboom P, van Exel E, Hoozemans JJ, Veerhuis R, Rozemuller AJ, van Gool WA (2010) Neuroinflammation - an early event in both the history and pathogenesis of Alzheimer’s disease. Neurodegener Dis 7:38–41
    • (2010) Neurodegener Dis , vol.7 , pp. 38-41
    • Eikelenboom, P.1    van Exel, E.2    Hoozemans, J.J.3    Veerhuis, R.4    Rozemuller, A.J.5    van Gool, W.A.6
  • 11
    • 77950363010 scopus 로고    scopus 로고
    • Mechanisms underlying inflammation in neurodegeneration
    • COI: 1:CAS:528:DC%2BC3cXlsVSgu7Y%3D, PID: 20303880
    • Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140:918–934
    • (2010) Cell , vol.140 , pp. 918-934
    • Glass, C.K.1    Saijo, K.2    Winner, B.3    Marchetto, M.C.4    Gage, F.H.5
  • 12
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics
    • COI: 1:CAS:528:DC%2BD38Xls1Cju7s%3D, PID: 12130773
    • Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 297:353–356
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 13
    • 77956961694 scopus 로고    scopus 로고
    • Neuroinflammatory processes in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC3cXpvVSrsL0%3D, PID: 20632195
    • Heneka MT, O’Banion MK, Terwel D, Kummer MP (2010) Neuroinflammatory processes in Alzheimer’s disease. J Neural Transm 117:919–947
    • (2010) J Neural Transm , vol.117 , pp. 919-947
    • Heneka, M.T.1    O’Banion, M.K.2    Terwel, D.3    Kummer, M.P.4
  • 14
    • 58849084518 scopus 로고    scopus 로고
    • Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25–35): involvement of lipid rafts
    • COI: 1:CAS:528:DC%2BD1MXjt1ShsL4%3D, PID: 19158430
    • Hernandez P, Lee G, Sjoberg M, Maccioni RB (2009) Tau phosphorylation by cdk5 and Fyn in response to amyloid peptide Abeta (25–35): involvement of lipid rafts. J Alzheimers Dis 16:149–156
    • (2009) J Alzheimers Dis , vol.16 , pp. 149-156
    • Hernandez, P.1    Lee, G.2    Sjoberg, M.3    Maccioni, R.B.4
  • 16
    • 77749336528 scopus 로고    scopus 로고
    • Amyloid-beta neurotoxicity in organotypic culture is attenuated by melatonin: involvement of GSK-3beta, tau and neuroinflammation
    • COI: 1:CAS:528:DC%2BC3cXktFKqtbk%3D, PID: 20136701
    • Hoppe JB, Frozza RL, Horn AP, Comiran RA, Bernardi A, Campos MM, Battastini AM, Salbego C (2010) Amyloid-beta neurotoxicity in organotypic culture is attenuated by melatonin: involvement of GSK-3beta, tau and neuroinflammation. J Pineal Res 48:230–238
    • (2010) J Pineal Res , vol.48 , pp. 230-238
    • Hoppe, J.B.1    Frozza, R.L.2    Horn, A.P.3    Comiran, R.A.4    Bernardi, A.5    Campos, M.M.6    Battastini, A.M.7    Salbego, C.8
  • 17
    • 0027938567 scopus 로고
    • Demonstration of CRP immunoreactivity in brains of Alzheimer’s disease: immunohistochemical study using formic acid pretreatment of tissue sections
    • COI: 1:CAS:528:DyaK2cXmtVahu7c%3D, PID: 7824175
    • Iwamoto N, Nishiyama E, Ohwada J, Arai H (1994) Demonstration of CRP immunoreactivity in brains of Alzheimer’s disease: immunohistochemical study using formic acid pretreatment of tissue sections. Neurosci Lett 177:23–26
    • (1994) Neurosci Lett , vol.177 , pp. 23-26
    • Iwamoto, N.1    Nishiyama, E.2    Ohwada, J.3    Arai, H.4
  • 18
    • 25644456097 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD2MXhtVOqs7rP, PID: 16192374
    • Kitazawa M, Oddo S, Yamasaki TR, Green KN, LaFerla FM (2005) Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer’s disease. J Neurosci 25:8843–8853
    • (2005) J Neurosci , vol.25 , pp. 8843-8853
    • Kitazawa, M.1    Oddo, S.2    Yamasaki, T.R.3    Green, K.N.4    LaFerla, F.M.5
  • 19
    • 37349109154 scopus 로고    scopus 로고
    • Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3
    • COI: 1:CAS:528:DC%2BD2sXhsVOktrjP, PID: 18031715
    • Koh SH, Noh MY, Kim SH (2008) Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3. Brain Res 1188:254–262
    • (2008) Brain Res , vol.1188 , pp. 254-262
    • Koh, S.H.1    Noh, M.Y.2    Kim, S.H.3
  • 20
    • 79955654426 scopus 로고    scopus 로고
    • Inhibition of Akt (ser473) phosphorylation and rapamycin-resistant cell growth by knockdown of mammalian target of rapamycin with small interfering RNA in vascular endothelial growth factor receptor-1-targeting vector
    • COI: 1:CAS:528:DC%2BC38XnvFCrsQ%3D%3D, PID: 21532145
    • Koide H, Asai T, Furuya K, Tsuzuku T, Kato H, Dewa T, Nango M, Maeda N, Oku N (2011) Inhibition of Akt (ser473) phosphorylation and rapamycin-resistant cell growth by knockdown of mammalian target of rapamycin with small interfering RNA in vascular endothelial growth factor receptor-1-targeting vector. Biol Pharm Bull 34:602–608
    • (2011) Biol Pharm Bull , vol.34 , pp. 602-608
    • Koide, H.1    Asai, T.2    Furuya, K.3    Tsuzuku, T.4    Kato, H.5    Dewa, T.6    Nango, M.7    Maeda, N.8    Oku, N.9
  • 21
    • 0037336701 scopus 로고    scopus 로고
    • Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway
    • COI: 1:CAS:528:DC%2BD3sXjtFylt7c%3D, PID: 12629164
    • Li Y, Liu L, Barger SW, Griffin WS (2003) Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci 23:1605–1611
    • (2003) J Neurosci , vol.23 , pp. 1605-1611
    • Li, Y.1    Liu, L.2    Barger, S.W.3    Griffin, W.S.4
  • 22
    • 67349220183 scopus 로고    scopus 로고
    • Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD1MXis1Chu7o%3D
    • Lin HB, Yang XM, Li TJ, Cheng YF, Zhang HT, Xu JP (2009) Memory deficits and neurochemical changes induced by C-reactive protein in rats: implication in Alzheimer’s disease. Psychopharmacology (Berl) 204:705–714
    • (2009) Psychopharmacology (Berl) , vol.204 , pp. 705-714
    • Lin, H.B.1    Yang, X.M.2    Li, T.J.3    Cheng, Y.F.4    Zhang, H.T.5    Xu, J.P.6
  • 24
    • 0035696284 scopus 로고    scopus 로고
    • The pentraxins: possible role in Alzheimer’s disease and other innate inflammatory diseases
    • COI: 1:CAS:528:DC%2BD3MXptFylurg%3D, PID: 11754991
    • McGeer EG, Yasojima K, Schwab C, McGeer PL (2001) The pentraxins: possible role in Alzheimer’s disease and other innate inflammatory diseases. Neurobiol Aging 22:843–848
    • (2001) Neurobiol Aging , vol.22 , pp. 843-848
    • McGeer, E.G.1    Yasojima, K.2    Schwab, C.3    McGeer, P.L.4
  • 25
    • 84897954153 scopus 로고    scopus 로고
    • New perspectives on the role of tau in Alzheimer’s disease. Implications for therapy
    • COI: 1:CAS:528:DC%2BC2cXitV2ju7o%3D, PID: 24462919
    • Medina M, Avila J (2014) New perspectives on the role of tau in Alzheimer’s disease. Implications for therapy. Biochem Pharmacol 88:540–547
    • (2014) Biochem Pharmacol , vol.88 , pp. 540-547
    • Medina, M.1    Avila, J.2
  • 26
    • 0002235557 scopus 로고    scopus 로고
    • The essential role of inflammation and induced gene expression in the pathogenic pathway of Alzheimer’s disease
    • COI: 1:CAS:528:DyaK1cXjsFCksrk%3D, PID: 9545438
    • Nilsson L, Rogers J, Potter H (1998) The essential role of inflammation and induced gene expression in the pathogenic pathway of Alzheimer’s disease. Front Biosci 3:d436–d446
    • (1998) Front Biosci , vol.3 , pp. 436-446
    • Nilsson, L.1    Rogers, J.2    Potter, H.3
  • 27
    • 84855186126 scopus 로고    scopus 로고
    • Pentraxins and Alzheimer’s disease: at the interface between biomarkers and pharmacological targets
    • COI: 1:CAS:528:DC%2BC38Xjs1Cqtbw%3D, PID: 22186030
    • Osera C, Pascale A, Amadio M, Venturini L, Govoni S, Ricevuti G (2012) Pentraxins and Alzheimer’s disease: at the interface between biomarkers and pharmacological targets. Ageing Res Rev 11:189–198
    • (2012) Ageing Res Rev , vol.11 , pp. 189-198
    • Osera, C.1    Pascale, A.2    Amadio, M.3    Venturini, L.4    Govoni, S.5    Ricevuti, G.6
  • 30
    • 0035696320 scopus 로고    scopus 로고
    • The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
    • COI: 1:CAS:528:DC%2BD3MXptFylu7s%3D, PID: 11755000
    • Potter H, Wefes IM, Nilsson LN (2001) The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation. Neurobiol Aging 22:923–930
    • (2001) Neurobiol Aging , vol.22 , pp. 923-930
    • Potter, H.1    Wefes, I.M.2    Nilsson, L.N.3
  • 31
    • 1642420308 scopus 로고    scopus 로고
    • Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway
    • COI: 1:CAS:528:DC%2BD2cXis1Wgs7w%3D, PID: 15051507
    • Quintanilla RA, Orellana DI, Gonzalez-Billault C, Maccioni RB (2004) Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Exp Cell Res 295:245–257
    • (2004) Exp Cell Res , vol.295 , pp. 245-257
    • Quintanilla, R.A.1    Orellana, D.I.2    Gonzalez-Billault, C.3    Maccioni, R.B.4
  • 33
    • 33747425620 scopus 로고    scopus 로고
    • GSK-3 is essential in the pathogenesis of Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD28XotFKktLo%3D, PID: 16914869
    • Takashima A (2006) GSK-3 is essential in the pathogenesis of Alzheimer’s disease. J Alzheimers Dis 9:309–317
    • (2006) J Alzheimers Dis , vol.9 , pp. 309-317
    • Takashima, A.1
  • 34
    • 0029010736 scopus 로고
    • Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis
    • COI: 1:CAS:528:DyaK2MXls1alur0%3D, PID: 7753801
    • Tennent GA, Lovat LB, Pepys MB (1995) Serum amyloid P component prevents proteolysis of the amyloid fibrils of Alzheimer disease and systemic amyloidosis. Proc Natl Acad Sci U S A 92:4299–4303
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 4299-4303
    • Tennent, G.A.1    Lovat, L.B.2    Pepys, M.B.3
  • 35
    • 67849126665 scopus 로고    scopus 로고
    • Plasma C-reactive protein is related to cognitive deterioration and dementia in patients with mild cognitive impairment
    • COI: 1:CAS:528:DC%2BD1MXptl2isL4%3D, PID: 19419739
    • Xu G, Zhou Z, Zhu W, Fan X, Liu X (2009) Plasma C-reactive protein is related to cognitive deterioration and dementia in patients with mild cognitive impairment. J Neurol Sci 284:77–80
    • (2009) J Neurol Sci , vol.284 , pp. 77-80
    • Xu, G.1    Zhou, Z.2    Zhu, W.3    Fan, X.4    Liu, X.5
  • 36
    • 0034704261 scopus 로고    scopus 로고
    • Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD3cXovFGkuro%3D, PID: 11134592
    • Yasojima K, Schwab C, McGeer EG, McGeer PL (2000) Human neurons generate C-reactive protein and amyloid P: upregulation in Alzheimer’s disease. Brain Res 887:80–89
    • (2000) Brain Res , vol.887 , pp. 80-89
    • Yasojima, K.1    Schwab, C.2    McGeer, E.G.3    McGeer, P.L.4
  • 37
    • 79551543865 scopus 로고    scopus 로고
    • Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3beta pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation
    • COI: 1:CAS:528:DC%2BC3MXhtlSqs7o%3D, PID: 21129477
    • Zhao R, Zhang Z, Song Y, Wang D, Qi J, Wen S (2011) Implication of phosphatidylinositol-3 kinase/Akt/glycogen synthase kinase-3beta pathway in ginsenoside Rb1’s attenuation of beta-amyloid-induced neurotoxicity and tau phosphorylation. J Ethnopharmacol 133:1109–1116
    • (2011) J Ethnopharmacol , vol.133 , pp. 1109-1116
    • Zhao, R.1    Zhang, Z.2    Song, Y.3    Wang, D.4    Qi, J.5    Wen, S.6
  • 38
    • 0033782845 scopus 로고    scopus 로고
    • Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease
    • COI: 1:CAS:528:DC%2BD3cXotVKnu78%3D, PID: 11079778
    • Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA (2000) Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol 59:880–888
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 880-888
    • Zhu, X.1    Rottkamp, C.A.2    Boux, H.3    Takeda, A.4    Perry, G.5    Smith, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.