Phospholipase D1 Couples CD4+ T Cell Activation to c-Myc-Dependent Deoxyribonucleotide Pool Expansion and HIV-1 Replication

PLoS Pathogens

Volumn 11, Issue 5, 2015, Pages

  Taylor, Harry E ^a   Simmons, Glenn E ^b   Mathews, Thomas P ^c   Khatua, Atanu K ^d   Popik, Waldemar ^d   Lindsley, Craig W ^c,e   D’Aquila, Richard T ^a   Brown, H Alex ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MEHARRY MEDICAL COLLEGE   (United States)

^e VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1, 4 DIAMINO 1, 4 BIS (2 AMINOPHENYLTHIO) 2, 3 DICYANOBUTADIENE; COMPLEMENTARY DNA; DEOXYRIBONUCLEOTIDE; GLUCOSE TRANSPORTER 1; MYC PROTEIN; PHOSPHOLIPASE D1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MESSENGER RNA; MYC PROTEIN, HUMAN; PHOSPHOLIPASE D;

ARTICLE; CD4+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; FLOW CYTOMETRY; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NONHUMAN; NUCLEOTIDE METABOLISM; ONCOGENE C MYC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE ACTIVATION; VIRUS REPLICATION; WESTERN BLOTTING; APOPTOSIS; CELL CULTURE; DNA REPLICATION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

APOPTOSIS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; DEOXYRIBONUCLEOTIDES; DNA REPLICATION; HIV INFECTIONS; HIV-1; HUMANS; LYMPHOCYTE ACTIVATION; PHOSPHOLIPASE D; PROTO-ONCOGENE PROTEINS C-MYC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VIRUS REPLICATION;

EID: 84930352391     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004864     Document Type: Article

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