Human Phospholipase D Activity Transiently Regulates Pyrimidine Biosynthesis in Malignant Gliomas

ACS Chemical Biology

Volumn 10, Issue 5, 2015, Pages 1258-1268

  Mathews, Thomas P ^a,b   Hill, Salisha ^b   Rose, Kristie L ^b   Ivanova, Pavlina T ^a   Lindsley, Craig W ^a,b,c   Brown, H Alex ^a,b  

^a VANDERBILT INGRAM CANCER CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOSIDE TRIPHOSPHATE; PHOSPHATIDIC ACID; PHOSPHOLIPASE D; PROTEIN KINASE B; ENZYME INHIBITOR; MTOR PROTEIN, HUMAN; PYRIMIDINE DERIVATIVE; TARGET OF RAPAMYCIN KINASE;

ARTICLE; CANCER CELL LINE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; METABOLOMICS; PRIORITY JOURNAL; PROTEOMICS; PYRIMIDINE SYNTHESIS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BRAIN TUMOR; CHEMISTRY; ENZYMOLOGY; GLIOMA; METABOLISM; MOLECULAR GENETICS; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE;

AMINO ACID SEQUENCE; BRAIN NEOPLASMS; CELL LINE, TUMOR; ENZYME INHIBITORS; GLIOMA; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASE D; PYRIMIDINES; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TOR SERINE-THREONINE KINASES;

EID: 84929580962     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb500772c     Document Type: Article

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