Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV β-chemokines: An approach to suppress R5 strains of HIV-1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 18, 2003, Pages 10411-10416

  Heredia, A ^a   Amoroso, A ^a   Davis, C ^a   Le, N ^a   Reardon, E ^a   Dominique, J K ^a   Klingebiel, E ^a   Gallo, R C ^a   Redfield, R R ^a  

^a INSTITUTE OF HUMAN VIROLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR CCR5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; N [4 [[[6,7 DIHYDRO 2 (4 METHYLPHENYL) 5H BENZOCYCLOHEPTEN 8 YL]CARBONYL]AMINO]BENZYL] N,N DIMETHYL 2H TETRAHYDROPYRAN 4 AMINIUM CHLORIDE; RAPAMYCIN;

ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR SPACE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPHARMACOLOGY; INFECTION PREVENTION; INFECTION RESISTANCE; LYMPHOCYTE; MACROPHAGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN;

AMIDES; ANTI-HIV AGENTS; CELLS, CULTURED; CHEMOKINES, CC; DOWN-REGULATION; HIV-1; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; QUATERNARY AMMONIUM COMPOUNDS; RANTES; RECEPTORS, CCR5; SIROLIMUS; T-LYMPHOCYTES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; RNA VIRUSES;

EID: 0041335573     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1834278100     Document Type: Article

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