The DNA Helicase Recql4 Is Required for Normal Osteoblast Expansion and Osteosarcoma Formation

PLoS Genetics

Volumn 11, Issue 4, 2015, Pages

  Ng, Alvin J M ^a,b   Walia, Mannu K ^a   Smeets, Monique F ^a   Mutsaers, Anthony J ^a,c   Sims, Natalie A ^a,b   Purton, Louise E ^a,b   Walsh, Nicole C ^a,b   Martin, T John ^a,b   Walkley, Carl R ^a,b  

^a ST VINCENT'S INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DNA HELICASE; RECQ14 HELICASE; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; PROTEIN P53; RECQ HELICASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; BONE LENGTH; BONE MASS; BONE MINERALIZATION; CANCER INHIBITION; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL EXPANSION; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME DEFICIENCY; GENE DELETION; GENE MUTATION; GENE SILENCING; IN VIVO STUDY; MALE; MITOSIS INHIBITION; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOCYTE; OSTEOSARCOMA; PHENOTYPE; STEM CELL; SURVIVAL TIME; ANIMAL; BONE TUMOR; C57BL MOUSE; CELL PROLIFERATION; GENETICS; METABOLISM;

ANIMALIA; MUS;

ANIMALS; BONE NEOPLASMS; CELL PROLIFERATION; GENE DELETION; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOGENESIS; OSTEOSARCOMA; RECQ HELICASES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84930344006     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005160     Document Type: Article

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