Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases

Folia Pharmacologica Japonica

Volumn 119, Issue 4, 2002, Pages 219-226

  Ichikawa, Koji ^a   Noda, Tetsuo ^a   Furuichi, Yasuhiro ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Bloom syndrome; Gene target knockout mice; RecQ helicase; Rothmund Thomson syndrome; Werner syndrome

Indexed keywords

BLM HELICASE; HELICASE; RECQ HELICASE; RECQ1 HELICASE; RECQ5 HELICASE; RTS HELICASE; UNCLASSIFIED DRUG; WRN HELICASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BLOOM SYNDROME; CANCER RISK; CHROMOSOME ABERRATION; CLINICAL FEATURE; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENE TARGETING; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PREMATURE AGING; REVIEW; ROTHMUND THOMSON SYNDROME; WERNER SYNDROME;

AGING, PREMATURE; ANIMALS; BLOOM SYNDROME; DISEASE MODELS, ANIMAL; DNA HELICASES; GENE TARGETING; HUMANS; MICE; MICE, KNOCKOUT; MUTATION; ROTHMUND-THOMSON SYNDROME; WERNER SYNDROME;

EID: 0036233108     PISSN: 00155691     EISSN: None     Source Type: Journal    
DOI: 10.1254/fpj.119.219     Document Type: Review

References (20)

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