메뉴 건너뛰기




Volumn 804, Issue , 2014, Pages 129-145

RECQ DNA helicases and osteosarcoma

Author keywords

Bloom syndrome; DNA helicase; Osteosarcoma; RECQ; RECQL4; Rothmund Thomson syndrome; RTS; Werner syndrome

Indexed keywords

PROTEIN P53; RECQ HELICASE; RECQL4 PROTEIN, HUMAN;

EID: 84907171910     PISSN: 00652598     EISSN: 22148019     Source Type: Book Series    
DOI: 10.1007/978-3-319-04843-7_7     Document Type: Article
Times cited : (29)

References (100)
  • 1
    • 84886793033 scopus 로고    scopus 로고
    • Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor
    • Aggarwal M, Banerjee T, Sommers JA et al (2013) Targeting an Achilles’ heel of cancer with a WRN helicase inhibitor. Cell Cycle 12(20):3329-3335
    • (2013) Cell Cycle , vol.12 , Issue.20 , pp. 3329-3335
    • Aggarwal, M.1    Banerjee, T.2    Sommers, J.A.3
  • 2
    • 79952127438 scopus 로고    scopus 로고
    • Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress
    • Aggarwal M, Sommers JA, Shoemaker RH et al (2011) Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress. Proc Natl Acad Sci U S A 108(4):1525-1530
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.4 , pp. 1525-1530
    • Aggarwal, M.1    Sommers, J.A.2    Shoemaker, R.H.3
  • 3
    • 0141567744 scopus 로고    scopus 로고
    • RecQ helicases: Suppressors of tumorigenesis and premature aging
    • Bachrati CZ, Hickson ID (2003) RecQ helicases: suppressors of tumorigenesis and premature aging. Biochem J 374(Pt 3):577-606
    • (2003) Biochem J , vol.374 , pp. 577-606
    • Bachrati, C.Z.1    Hickson, I.D.2
  • 4
    • 84861014887 scopus 로고    scopus 로고
    • Embryonic signaling pathways and rhabdomyosarcoma: Contributions to cancer development and opportunities for therapeutic targeting
    • Belyea B, Kephart JG, Blum J et al (2012) Embryonic signaling pathways and rhabdomyosarcoma: contributions to cancer development and opportunities for therapeutic targeting. Sarcoma 2012:406-239
    • (2012) Sarcoma , vol.2012 , pp. 239-406
    • Belyea, B.1    Kephart, J.G.2    Blum, J.3
  • 6
    • 33847641404 scopus 로고    scopus 로고
    • Nuclear import and retention domains in the amino terminus of RECQL4
    • Burks LM, Yin J, Plon SE (2007) Nuclear import and retention domains in the amino terminus of RECQL4. Gene 391(1-2):26-38
    • (2007) Gene , vol.391 , Issue.1-2 , pp. 26-38
    • Burks, L.M.1    Yin, J.2    Plon, S.E.3
  • 7
    • 49249109473 scopus 로고    scopus 로고
    • Identifi cation of new RECQL4 mutations in Caucasian Rothmund-Thomson patients and analysis of sensitivity to a wide range of genotoxic agents
    • Cabral RE, Queille S, Bodemer C et al (2008) Identifi cation of new RECQL4 mutations in Caucasian Rothmund-Thomson patients and analysis of sensitivity to a wide range of genotoxic agents. Mutat Res 643(1-2):41-47
    • (2008) Mutat Res , vol.643 , Issue.1-2 , pp. 41-47
    • Cabral, R.E.1    Queille, S.2    Bodemer, C.3
  • 8
    • 77956182397 scopus 로고    scopus 로고
    • Rb regulates fate choice and lineage commitment in vivo
    • Calo E, Quintero-Estades JA, Danielian PS et al (2010) Rb regulates fate choice and lineage commitment in vivo. Nature 466(7310):1110-1114
    • (2010) Nature , vol.466 , Issue.7310 , pp. 1110-1114
    • Calo, E.1    Quintero-Estades, J.A.2    Danielian, P.S.3
  • 9
    • 71449108720 scopus 로고    scopus 로고
    • Drosophila RecQ4 has a 3′-5′ DNA helicase activity that is essential for viability
    • Capp C, Wu J, Hsieh TS (2009) Drosophila RecQ4 has a 3′-5′ DNA helicase activity that is essential for viability. J Biol Chem 284(45):30845-30852
    • (2009) J Biol Chem , vol.284 , Issue.45 , pp. 30845-30852
    • Capp, C.1    Wu, J.2    Hsieh, T.S.3
  • 10
    • 84864777636 scopus 로고    scopus 로고
    • RecQL4 cytoplasmic localization: Implications in mitochondrial DNA oxidative damage repair
    • Chi Z, Nie L, Peng Z et al (2012) RecQL4 cytoplasmic localization: implications in mitochondrial DNA oxidative damage repair. Int J Biochem Cell Biol 44(11):1942-1951
    • (2012) Int J Biochem Cell Biol , vol.44 , Issue.11 , pp. 1942-1951
    • Chi, Z.1    Nie, L.2    Peng, Z.3
  • 11
    • 69249209608 scopus 로고    scopus 로고
    • RecQ helicases: Multifunctional genome caretakers
    • Chu WK, Hickson ID (2009) RecQ helicases: multifunctional genome caretakers. Nat Rev Cancer 9(9):644-654
    • (2009) Nat Rev Cancer , vol.9 , Issue.9 , pp. 644-654
    • Chu, W.K.1    Hickson, I.D.2
  • 12
    • 70649090109 scopus 로고    scopus 로고
    • Profi ling of high-grade central osteosarcoma and its putative progenitor cells identifi es tumourigenic pathways
    • Cleton-Jansen AM, Anninga JK, Briaire-de Bruijin IH et al (2009) Profi ling of high-grade central osteosarcoma and its putative progenitor cells identifi es tumourigenic pathways. Br J Cancer 101(11):1909-1918
    • (2009) Br J Cancer , vol.101 , Issue.11 , pp. 1909-1918
    • Cleton-Jansen, A.M.1    Anninga, J.K.2    Briaire-de Bruijin, I.H.3
  • 13
    • 84869209147 scopus 로고    scopus 로고
    • Drosophila RecQ4 is directly involved in both DNA replication and the response to UV damage in S2 cells
    • Crevel G, Vo N, Crevel I et al (2012) Drosophila RecQ4 is directly involved in both DNA replication and the response to UV damage in S2 cells. PLoS One 7(11):e49505
    • (2012) PLoS One , vol.7 , Issue.11
    • Crevel, G.1    Vo, N.2    Crevel, I.3
  • 14
    • 84862782942 scopus 로고    scopus 로고
    • RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
    • Croteau DL, Rossi ML, Canugovi C et al (2012) RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity. Aging Cell 11(3):456-466
    • (2012) Aging Cell , vol.11 , Issue.3 , pp. 456-466
    • Croteau, D.L.1    Rossi, M.L.2    Canugovi, C.3
  • 15
    • 84865074479 scopus 로고    scopus 로고
    • RAPADILINO RECQL4 mutant protein lacks helicase and ATPase activity
    • Croteau DL, Rossi ML, Ross J et al (2012) RAPADILINO RECQL4 mutant protein lacks helicase and ATPase activity. Biochim Biophys Acta 1822(11):1727-1734
    • (2012) Biochim Biophys Acta , vol.1822 , Issue.11 , pp. 1727-1734
    • Croteau, D.L.1    Rossi, M.L.2    Ross, J.3
  • 16
    • 84864804909 scopus 로고    scopus 로고
    • RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress
    • De S, Kumari J, Mudgal R et al (2012) RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress. J Cell Sci 125(Pt 10):2509-2522
    • (2012) J Cell Sci , vol.125 , pp. 2509-2522
    • De, S.1    Kumari, J.2    Mudgal, R.3
  • 17
    • 63749107674 scopus 로고    scopus 로고
    • A patient with Baller-Gerold syndrome and midline NK/T lymphoma
    • Debeljak M, Zver A, Jazbec J (2009) A patient with Baller-Gerold syndrome and midline NK/T lymphoma. Am J Med Genet A 149A(4):755-759
    • (2009) Am J Med Genet A , vol.149 A , Issue.4 , pp. 755-759
    • Debeljak, M.1    Zver, A.2    Jazbec, J.3
  • 18
    • 66849089384 scopus 로고    scopus 로고
    • p300-mediated acetylation of the Rothmund- Thomson-syndrome gene product RECQL4 regulates its subcellular localization
    • Dietschy T, Shevelev I, Pena-Diaz J et al (2009) p300-mediated acetylation of the Rothmund- Thomson-syndrome gene product RECQL4 regulates its subcellular localization. J Cell Sci 122(Pt 8):1258-1267
    • (2009) J Cell Sci , vol.122 , pp. 1258-1267
    • Dietschy, T.1    Shevelev, I.2    Pena-Diaz, J.3
  • 19
    • 0031040591 scopus 로고    scopus 로고
    • Osteosarcomatosis with Rothmund-Thomson syndrome
    • el-Khoury JM, Haddad SN, Atallah NG (1997) Osteosarcomatosis with Rothmund-Thomson syndrome. Br J Radiol 70:215-218
    • (1997) Br J Radiol , vol.70 , pp. 215-218
    • el-Khoury, J.M.1    Haddad, S.N.2    Atallah, N.G.3
  • 20
    • 81355160516 scopus 로고    scopus 로고
    • Genetic mouse models for bone studies strengths and limitations
    • Elefteriou F, Yang X (2011) Genetic mouse models for bone studies strengths and limitations. Bone 49(6):1242-1254
    • (2011) Bone , vol.49 , Issue.6 , pp. 1242-1254
    • Elefteriou, F.1    Yang, X.2
  • 21
    • 0028785586 scopus 로고
    • The Bloom’s syndrome gene product is homologous to RecQ helicases
    • Ellis NA, Groden J, Ye TZ et al (1995) The Bloom’s syndrome gene product is homologous to RecQ helicases. Cell 83(4):655-666
    • (1995) Cell , vol.83 , Issue.4 , pp. 655-666
    • Ellis, N.A.1    Groden, J.2    Ye, T.Z.3
  • 22
    • 57649198428 scopus 로고    scopus 로고
    • RecQ4 facilitates UV light-induced DNA damage repair through interaction with nucleotide excision repair factor xeroderma pigmentosum group A (XPA)
    • Fan W, Luo J (2008) RecQ4 facilitates UV light-induced DNA damage repair through interaction with nucleotide excision repair factor xeroderma pigmentosum group A (XPA). J Biol Chem 283(43):29037-29044
    • (2008) J Biol Chem , vol.283 , Issue.43 , pp. 29037-29044
    • Fan, W.1    Luo, J.2
  • 23
    • 84878655148 scopus 로고    scopus 로고
    • The RECQL4 protein, defi cient in Rothmund- Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesions
    • Ferrarelli LK, Popuri V, Ghosh AK et al (2013) The RECQL4 protein, defi cient in Rothmund- Thomson syndrome is active on telomeric D-loops containing DNA metabolism blocking lesions. DNA Repair (Amst) 12(7):518-528
    • (2013) DNA Repair (Amst) , vol.12 , Issue.7 , pp. 518-528
    • Ferrarelli, L.K.1    Popuri, V.2    Ghosh, A.K.3
  • 24
    • 0028831333 scopus 로고
    • Bloom’s syndrome
    • German J (1995) Bloom’s syndrome. Dermatol Clin 13(1):7-18
    • (1995) Dermatol Clin , vol.13 , Issue.1 , pp. 7-18
    • German, J.1
  • 25
    • 0031052108 scopus 로고    scopus 로고
    • Bloom’s syndrome. XX. The fi rst 100 cancers
    • German J (1997) Bloom’s syndrome. XX. The fi rst 100 cancers. Cancer Genet Cytogenet 93(1):100-106
    • (1997) Cancer Genet Cytogenet , vol.93 , Issue.1 , pp. 100-106
    • German, J.1
  • 26
    • 84855266777 scopus 로고    scopus 로고
    • RECQL4, the protein mutated in Rothmund- Thomson syndrome, functions in telomere maintenance
    • Ghosh AK, Rossi ML, Singh DK et al (2012) RECQL4, the protein mutated in Rothmund- Thomson syndrome, functions in telomere maintenance. J Biol Chem 287(1):196-209
    • (2012) J Biol Chem , vol.287 , Issue.1 , pp. 196-209
    • Ghosh, A.K.1    Rossi, M.L.2    Singh, D.K.3
  • 27
    • 34250848174 scopus 로고    scopus 로고
    • In vivo analysis of Wnt signaling in bone
    • Glass DA, Karsenty G (2007) In vivo analysis of Wnt signaling in bone. Endocrinology 148(6):2630-2634
    • (2007) Endocrinology , vol.148 , Issue.6 , pp. 2630-2634
    • Glass, D.A.1    Karsenty, G.2
  • 28
    • 0037663490 scopus 로고    scopus 로고
    • Werner syndrome protein limits MYC-induced cellular senescence
    • Grandori C, Wu KJ, Fernandez P et al (2003) Werner syndrome protein limits MYC-induced cellular senescence. Genes Dev 17(13):1569-1574
    • (2003) Genes Dev , vol.17 , Issue.13 , pp. 1569-1574
    • Grandori, C.1    Wu, K.J.2    Fernandez, P.3
  • 29
    • 33846998643 scopus 로고    scopus 로고
    • Clinicopathologic features of osteosarcoma in patients with Rothmund-Thomson syndrome
    • Hicks MJ, Roth JR, Kozinetz CA et al (2007) Clinicopathologic features of osteosarcoma in patients with Rothmund-Thomson syndrome. J Clin Oncol 25(4):370-375
    • (2007) J Clin Oncol , vol.25 , Issue.4 , pp. 370-375
    • Hicks, M.J.1    Roth, J.R.2    Kozinetz, C.A.3
  • 30
    • 10744225050 scopus 로고    scopus 로고
    • Growth retardation and skin abnormalities of the Recql4-defi cient mouse
    • Hoki Y, Araki R, Fujimori A et al (2003) Growth retardation and skin abnormalities of the Recql4-defi cient mouse. Hum Mol Genet 12(18):2293-2299
    • (2003) Hum Mol Genet , vol.12 , Issue.18 , pp. 2293-2299
    • Hoki, Y.1    Araki, R.2    Fujimori, A.3
  • 31
    • 13444302715 scopus 로고    scopus 로고
    • Sequential roles of Hedgehog and Wnt signaling in osteoblast development
    • Hu H, Hilton MJ, Tu X et al (2005) Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development 132(1):49-60
    • (2005) Development , vol.132 , Issue.1 , pp. 49-60
    • Hu, H.1    Hilton, M.J.2    Tu, X.3
  • 32
    • 0036233108 scopus 로고    scopus 로고
    • Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases
    • Ichikawa K, Noda T, Furuichi Y (2002) Preparation of the gene targeted knockout mice for human premature aging diseases, Werner syndrome, and Rothmund-Thomson syndrome caused by the mutation of DNA helicases. Nippon Yakurigaku Zasshi 119(4):219-226
    • (2002) Nippon Yakurigaku Zasshi , vol.119 , Issue.4 , pp. 219-226
    • Ichikawa, K.1    Noda, T.2    Furuichi, Y.3
  • 33
    • 70349449240 scopus 로고    scopus 로고
    • Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins
    • Im JS, Ki SH, Farina A et al (2009) Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci U S A 106(37):15628-15632
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.37 , pp. 15628-15632
    • Im, J.S.1    Ki, S.H.2    Farina, A.3
  • 34
    • 84872544485 scopus 로고    scopus 로고
    • The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients
    • Jensen MB, Dunn CA, Keijzers G et al (2012) The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients. Aging (Albany NY) 4(11):790-802
    • (2012) Aging (Albany NY) , vol.4 , Issue.11 , pp. 790-802
    • Jensen, M.B.1    Dunn, C.A.2    Keijzers, G.3
  • 35
    • 45049086666 scopus 로고    scopus 로고
    • Sensitivity of RECQL4-defi cient fi broblasts from Rothmund-Thomson syndrome patients to genotoxic agents
    • Jin W, Liu H, Zhang Y et al (2008) Sensitivity of RECQL4-defi cient fi broblasts from Rothmund-Thomson syndrome patients to genotoxic agents. Hum Genet 123(6):643-653
    • (2008) Hum Genet , vol.123 , Issue.6 , pp. 643-653
    • Jin, W.1    Liu, H.2    Zhang, Y.3
  • 36
    • 0031658237 scopus 로고    scopus 로고
    • Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication
    • Kamimura Y, Masumoto H, Sugino A et al (1998) Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication. Mol Cell Biol 18(10):6102-6109
    • (1998) Mol Cell Biol , vol.18 , Issue.10 , pp. 6102-6109
    • Kamimura, Y.1    Masumoto, H.2    Sugino, A.3
  • 37
    • 65249167488 scopus 로고    scopus 로고
    • Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice
    • Kansara M, Tsang M, Kodjabachian L et al (2009) Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates osteosarcomagenesis in mice. J Clin Invest 119(4):837-851
    • (2009) J Clin Invest , vol.119 , Issue.4 , pp. 837-851
    • Kansara, M.1    Tsang, M.2    Kodjabachian, L.3
  • 38
    • 0032535661 scopus 로고    scopus 로고
    • Cloning of two new human helicase genes of the RecQ family: Biological signifi cance of multiple species in higher eukaryotes
    • Kitao S, Ohsugi I, Ichikawa K et al (1998) Cloning of two new human helicase genes of the RecQ family: biological signifi cance of multiple species in higher eukaryotes. Genomics 54(3):443-452
    • (1998) Genomics , vol.54 , Issue.3 , pp. 443-452
    • Kitao, S.1    Ohsugi, I.2    Ichikawa, K.3
  • 39
    • 0032939991 scopus 로고    scopus 로고
    • Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome
    • Kitao S, Shimamoto A, Goto M et al (1999) Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome. Nat Genet 22(1):82-84
    • (1999) Nat Genet , vol.22 , Issue.1 , pp. 82-84
    • Kitao, S.1    Shimamoto, A.2    Goto, M.3
  • 40
    • 77953014335 scopus 로고    scopus 로고
    • Purifi cation and characterization of RecQ helicases of plants
    • Kobbe D, Focke M, Puchta H (2010) Purifi cation and characterization of RecQ helicases of plants. Methods Mol Biol 587:195-209
    • (2010) Methods Mol Biol , vol.587 , pp. 195-209
    • Kobbe, D.1    Focke, M.2    Puchta, H.3
  • 41
    • 84864322966 scopus 로고    scopus 로고
    • The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation
    • Kohzaki M, Chiourea M, Versini G et al (2012) The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation. Carcinogenesis 33(6):1203-1210
    • (2012) Carcinogenesis , vol.33 , Issue.6 , pp. 1203-1210
    • Kohzaki, M.1    Chiourea, M.2    Versini, G.3
  • 42
    • 33947309418 scopus 로고    scopus 로고
    • Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts
    • Kumata Y, Tada S, Yamanada Y et al (2007) Possible involvement of RecQL4 in the repair of double-strand DNA breaks in Xenopus egg extracts. Biochim Biophys Acta 1773(4):556-564
    • (2007) Biochim Biophys Acta , vol.1773 , Issue.4 , pp. 556-564
    • Kumata, Y.1    Tada, S.2    Yamanada, Y.3
  • 43
    • 84875673276 scopus 로고    scopus 로고
    • Spectrum and risk of neoplasia in Werner syndrome: A systematic review
    • Lauper JM, Krause A, Vaughan TL et al (2013) Spectrum and risk of neoplasia in Werner syndrome: a systematic review. PLoS One 8(4):e59709
    • (2013) PLoS One , vol.8 , Issue.4
    • Lauper, J.M.1    Krause, A.2    Vaughan, T.L.3
  • 44
    • 70349985246 scopus 로고    scopus 로고
    • Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice
    • Lin PP, Pandey MK, Jin F et al (2009) Targeted mutation of p53 and Rb in mesenchymal cells of the limb bud produces sarcomas in mice. Carcinogenesis 30(10):1789-1795
    • (2009) Carcinogenesis , vol.30 , Issue.10 , pp. 1789-1795
    • Lin, P.P.1    Pandey, M.K.2    Jin, F.3
  • 45
    • 42149130812 scopus 로고    scopus 로고
    • Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fi xed paraffi n-embedded tumours
    • Linton KM, Hey Y, Saunders E et al (2008) Acquisition of biologically relevant gene expression data by Affymetrix microarray analysis of archival formalin-fi xed paraffi n-embedded tumours. Br J Cancer 98(8):1403-1414
    • (2008) Br J Cancer , vol.98 , Issue.8 , pp. 1403-1414
    • Linton, K.M.1    Hey, Y.2    Saunders, E.3
  • 46
    • 0036076389 scopus 로고    scopus 로고
    • Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer
    • Logan M, Martin JF, Nagy A et al (2002) Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33(2):77-80
    • (2002) Genesis , vol.33 , Issue.2 , pp. 77-80
    • Logan, M.1    Martin, J.F.2    Nagy, A.3
  • 47
    • 84857891632 scopus 로고    scopus 로고
    • On PAR with PARP: Cellular stress signaling through poly(ADPribose) and PARP-1
    • Luo X, Kraus WL (2012) On PAR with PARP: cellular stress signaling through poly(ADPribose) and PARP-1. Genes Dev 26(5):417-432
    • (2012) Genes Dev , vol.26 , Issue.5 , pp. 417-432
    • Luo, X.1    Kraus, W.L.2
  • 48
    • 30344477373 scopus 로고    scopus 로고
    • Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome
    • Macris MA, Krejci L, Bussen W et al (2006) Biochemical characterization of the RECQ4 protein, mutated in Rothmund-Thomson syndrome. DNA Repair (Amst) 5(2):172-180
    • (2006) DNA Repair (Amst) , vol.5 , Issue.2 , pp. 172-180
    • Macris, M.A.1    Krejci, L.2    Bussen, W.3
  • 49
    • 62549112664 scopus 로고    scopus 로고
    • Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma
    • 3p
    • Maire G, Yoshimoto M, Chilton-Macneill S et al (2009) Recurrent RECQL4 imbalance and increased gene expression levels are associated with structural chromosomal instability in sporadic osteosarcoma. Neoplasia 11(3):260-268, 3p
    • (2009) Neoplasia , vol.11 , Issue.3 , pp. 260-268
    • Maire, G.1    Yoshimoto, M.2    Chilton-Macneill, S.3
  • 50
    • 15544389502 scopus 로고    scopus 로고
    • Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome
    • Mann MB, Hodges CA, Barnes E et al (2005) Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet 14(6):813-825
    • (2005) Hum Mol Genet , vol.14 , Issue.6 , pp. 813-825
    • Mann, M.B.1    Hodges, C.A.2    Barnes, E.3
  • 51
    • 0034626770 scopus 로고    scopus 로고
    • Lessons from human progeroid syndromes
    • Martin GM, Oshima J (2000) Lessons from human progeroid syndromes. Nature 408(6809):263-266
    • (2000) Nature , vol.408 , Issue.6809 , pp. 263-266
    • Martin, G.M.1    Oshima, J.2
  • 52
    • 33745471225 scopus 로고    scopus 로고
    • The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication
    • Matsuno K, Kumano M, Kubota Y et al (2006) The N-terminal noncatalytic region of Xenopus RecQ4 is required for chromatin binding of DNA polymerase alpha in the initiation of DNA replication. Mol Cell Biol 26(13):4843-4852
    • (2006) Mol Cell Biol , vol.26 , Issue.13 , pp. 4843-4852
    • Matsuno, K.1    Kumano, M.2    Kubota, Y.3
  • 53
    • 49149105981 scopus 로고    scopus 로고
    • Radiographic abnormalities in Rothmund-Thomson syndrome and genotype-phenotype correlation with RECQL4 mutation status
    • Mehollin-Ray AR, Kozinetz CA, Schlesinger AE et al (2008) Radiographic abnormalities in Rothmund-Thomson syndrome and genotype-phenotype correlation with RECQL4 mutation status. AJR Am J Roentgenol 191(2):W62-W66
    • (2008) AJR Am J Roentgenol , vol.191 , Issue.2 , pp. 62-66
    • Mehollin-Ray, A.R.1    Kozinetz, C.A.2    Schlesinger, A.E.3
  • 54
    • 78649467087 scopus 로고    scopus 로고
    • Human RECQ helicases: Roles in DNA metabolism, mutagenesis and cancer biology
    • Monnat RJ Jr (2010) Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology. Semin Cancer Biol 20(5):329-339
    • (2010) Semin Cancer Biol , vol.20 , Issue.5 , pp. 329-339
    • Monnat, R.J.1
  • 55
    • 0030697336 scopus 로고    scopus 로고
    • A putative nucleic acid-binding domain in Bloom’s and Werner’s syndrome helicases
    • Morozov V, Mushegian AR, Koonin EV et al (1997) A putative nucleic acid-binding domain in Bloom’s and Werner’s syndrome helicases. Trends Biochem Sci 22(11):417-418
    • (1997) Trends Biochem Sci , vol.22 , Issue.11 , pp. 417-418
    • Morozov, V.1    Mushegian, A.R.2    Koonin, E.V.3
  • 56
    • 0025015168 scopus 로고
    • A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
    • Moser AR, Pitot HC, Dove WF (1990) A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 247(4940):322-324
    • (1990) Science , vol.247 , Issue.4940 , pp. 322-324
    • Moser, A.R.1    Pitot, H.C.2    Dove, W.F.3
  • 57
    • 0021792806 scopus 로고
    • The recQ gene of Escherichia coli K12: Molecular cloning and isolation of insertion mutants
    • Nakayama K, Irino N, Nakayama H (1985) The recQ gene of Escherichia coli K12: molecular cloning and isolation of insertion mutants. Mol Gen Genet 200(2):266-271
    • (1985) Mol Gen Genet , vol.200 , Issue.2 , pp. 266-271
    • Nakayama, K.1    Irino, N.2    Nakayama, H.3
  • 58
    • 33947101323 scopus 로고    scopus 로고
    • Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: Identifi cation of candidate amplifi ed and overexpressed genes
    • Narayan G, Bourdon V, Chaganti S et al (2007) Gene dosage alterations revealed by cDNA microarray analysis in cervical cancer: identifi cation of candidate amplifi ed and overexpressed genes. Genes Chromosomes Cancer 46(4):373-384
    • (2007) Genes Chromosomes Cancer , vol.46 , Issue.4 , pp. 373-384
    • Narayan, G.1    Bourdon, V.2    Chaganti, S.3
  • 59
    • 84872966436 scopus 로고    scopus 로고
    • A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells
    • Nguyen GH, Dexheimer TS, Rosenthal AS et al (2013) A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells. Chem Biol 20(1):55-62
    • (2013) Chem Biol , vol.20 , Issue.1 , pp. 55-62
    • Nguyen, G.H.1    Dexheimer, T.S.2    Rosenthal, A.S.3
  • 60
    • 3242881657 scopus 로고    scopus 로고
    • Mutation analysis of the RECQL4 gene in sporadic osteosarcomas
    • Nishijo K, Nakayama T, Aoyama T et al (2004) Mutation analysis of the RECQL4 gene in sporadic osteosarcomas. Int J Cancer 111(3):367-372
    • (2004) Int J Cancer , vol.111 , Issue.3 , pp. 367-372
    • Nishijo, K.1    Nakayama, T.2    Aoyama, T.3
  • 61
    • 84866930447 scopus 로고    scopus 로고
    • The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif
    • Ohlenschlager O, Kuhnert A, Schneider A et al (2012) The N-terminus of the human RecQL4 helicase is a homeodomain-like DNA interaction motif. Nucleic Acids Res 40(17):8309-8324
    • (2012) Nucleic Acids Res , vol.40 , Issue.17 , pp. 8309-8324
    • Ohlenschlager, O.1    Kuhnert, A.2    Schneider, A.3
  • 62
    • 33846031118 scopus 로고    scopus 로고
    • A positive involvement of RecQL4 in UV-induced S-phase arrest
    • Park SJ, Lee YJ, Beck BD et al (2006) A positive involvement of RecQL4 in UV-induced S-phase arrest. DNA Cell Biol 25(12):696-703
    • (2006) DNA Cell Biol , vol.25 , Issue.12 , pp. 696-703
    • Park, S.J.1    Lee, Y.J.2    Beck, B.D.3
  • 63
    • 27144460601 scopus 로고    scopus 로고
    • The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability
    • Petkovic M, Dietschy T, Freire R et al (2005) The human Rothmund-Thomson syndrome gene product, RECQL4, localizes to distinct nuclear foci that coincide with proteins involved in the maintenance of genome stability. J Cell Sci 118(Pt 18):4261-4269
    • (2005) J Cell Sci , vol.118 , pp. 4261-4269
    • Petkovic, M.1    Dietschy, T.2    Freire, R.3
  • 64
    • 77953326659 scopus 로고    scopus 로고
    • Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding
    • Rossi ML, Ghosh AK, Kulikowicz T et al (2010) Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding. DNA Repair (Amst) 9(7):796-804
    • (2010) DNA Repair (Amst) , vol.9 , Issue.7 , pp. 796-804
    • Rossi, M.L.1    Ghosh, A.K.2    Kulikowicz, T.3
  • 65
    • 51249195723 scopus 로고
    • Ueber cataracten in verbindung mit einer eigenthumlichen hautdegeneration
    • Rothmund A (1868) Ueber cataracten in verbindung mit einer eigenthumlichen hautdegeneration. Arch Ophthamol 14:159-182
    • (1868) Arch Ophthamol , vol.14 , pp. 159-182
    • Rothmund, A.1
  • 66
    • 77952065237 scopus 로고    scopus 로고
    • Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy
    • Sadikovic B, Thorner P, Chilton-Macneill S et al (2010) Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. BMC Cancer 10:202
    • (2010) BMC Cancer , vol.10 , pp. 202
    • Sadikovic, B.1    Thorner, P.2    Chilton-Macneill, S.3
  • 67
    • 20444380748 scopus 로고    scopus 로고
    • Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome
    • Sangrithi MN, Bernal JA, Madine M et al (2005) Initiation of DNA replication requires the RECQL4 protein mutated in Rothmund-Thomson syndrome. Cell 121(6):887-898
    • (2005) Cell , vol.121 , Issue.6 , pp. 887-898
    • Sangrithi, M.N.1    Bernal, J.A.2    Madine, M.3
  • 68
    • 69449097526 scopus 로고    scopus 로고
    • Direct and indirect roles of RECQL4 in modulating base excision repair capacity
    • Schurman SH, Hedayati M, Wang Z et al (2009) Direct and indirect roles of RECQL4 in modulating base excision repair capacity. Hum Mol Genet 18(18):3470-3483
    • (2009) Hum Mol Genet , vol.18 , Issue.18 , pp. 3470-3483
    • Schurman, S.H.1    Hedayati, M.2    Wang, Z.3
  • 69
    • 20144383378 scopus 로고    scopus 로고
    • Tumor suppressor p53 represses transcription of RECQ4 helicase
    • Sengupta S, Shimamoto A, Koshiji M et al (2005) Tumor suppressor p53 represses transcription of RECQ4 helicase. Oncogene 24(10):1738-1748
    • (2005) Oncogene , vol.24 , Issue.10 , pp. 1738-1748
    • Sengupta, S.1    Shimamoto, A.2    Koshiji, M.3
  • 70
    • 0027534494 scopus 로고
    • A case of Rothmund-Thomson syndrome with reduced DNA repair capacity
    • Shinya A, Nishigori C, Moriwaki S et al (1993) A case of Rothmund-Thomson syndrome with reduced DNA repair capacity. Arch Dermatol 129(3):332-336
    • (1993) Arch Dermatol , vol.129 , Issue.3 , pp. 332-336
    • Shinya, A.1    Nishigori, C.2    Moriwaki, S.3
  • 71
    • 0242609126 scopus 로고    scopus 로고
    • Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases
    • Siitonen HA, Kopra O, Kaariainen H et al (2003) Molecular defect of RAPADILINO syndrome expands the phenotype spectrum of RECQL diseases. Hum Mol Genet 12(21):2837-2844
    • (2003) Hum Mol Genet , vol.12 , Issue.21 , pp. 2837-2844
    • Siitonen, H.A.1    Kopra, O.2    Kaariainen, H.3
  • 73
    • 77956707391 scopus 로고    scopus 로고
    • The involvement of human RECQL4 in DNA double-strand break repair
    • Singh DK, Karmakar P, Aamann M et al (2010) The involvement of human RECQL4 in DNA double-strand break repair. Aging Cell 9(3):358-371
    • (2010) Aging Cell , vol.9 , Issue.3 , pp. 358-371
    • Singh, D.K.1    Karmakar, P.2    Aamann, M.3
  • 74
    • 84864951093 scopus 로고    scopus 로고
    • The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability
    • Singh DK, Popuri V, Kulikowicz T et al (2012) The human RecQ helicases BLM and RECQL4 cooperate to preserve genome stability. Nucleic Acids Res 40(14):6632-6648
    • (2012) Nucleic Acids Res , vol.40 , Issue.14 , pp. 6632-6648
    • Singh, D.K.1    Popuri, V.2    Kulikowicz, T.3
  • 75
    • 0020066137 scopus 로고
    • Enhanced radiosensitivity and defective DNA repair in cultured fi broblasts derived from Rothmund Thomson syndrome patients
    • Smith PJ, Paterson MC (1982) Enhanced radiosensitivity and defective DNA repair in cultured fi broblasts derived from Rothmund Thomson syndrome patients. Mutat Res 94(1):213-228
    • (1982) Mutat Res , vol.94 , Issue.1 , pp. 213-228
    • Smith, P.J.1    Paterson, M.C.2
  • 76
    • 78549275857 scopus 로고    scopus 로고
    • Human RecQL4 helicase plays critical roles in prostate carcinogenesis
    • Su Y, Meador JA, Calaf GM et al (2010) Human RecQL4 helicase plays critical roles in prostate carcinogenesis. Cancer Res 70(22):9207-9217
    • (2010) Cancer Res , vol.70 , Issue.22 , pp. 9207-9217
    • Su, Y.1    Meador, J.A.2    Calaf, G.M.3
  • 77
    • 70449732463 scopus 로고    scopus 로고
    • DNA helicase activity in purifi ed human RECQL4 protein
    • Suzuki T, Kohno T, Ishimi Y (2009) DNA helicase activity in purifi ed human RECQL4 protein. J Biochem 146(3):327-335
    • (2009) J Biochem , vol.146 , Issue.3 , pp. 327-335
    • Suzuki, T.1    Kohno, T.2    Ishimi, Y.3
  • 78
    • 84880662044 scopus 로고    scopus 로고
    • Effi cient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction
    • Tanaka S, Komeda Y, Umemori T et al (2013) Effi cient initiation of DNA replication in eukaryotes requires Dpb11/TopBP1-GINS interaction. Mol Cell Biol 33(13):2614-2622
    • (2013) Mol Cell Biol , vol.33 , Issue.13 , pp. 2614-2622
    • Tanaka, S.1    Komeda, Y.2    Umemori, T.3
  • 79
    • 77950679225 scopus 로고    scopus 로고
    • Alteration of Notch signaling in skeletal development and disease
    • Tao J, Chen S, Lee B (2010) Alteration of Notch signaling in skeletal development and disease. Ann N Y Acad Sci 1192:257-268
    • (2010) Ann N Y Acad Sci , vol.1192 , pp. 257-268
    • Tao, J.1    Chen, S.2    Lee, B.3
  • 80
    • 3242804840 scopus 로고
    • Rothmund’s syndrome-Thomson’s syndrome
    • Taylor WB (1957) Rothmund’s syndrome-Thomson’s syndrome. Arch Dermatol 75:236-244
    • (1957) Arch Dermatol , vol.75 , pp. 236-244
    • Taylor, W.B.1
  • 81
    • 77749330814 scopus 로고    scopus 로고
    • Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation
    • Thangavel S, Mendoza-Maldonado R, Tissino E et al (2010) Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation. Mol Cell Biol 30(6): 1382-1396
    • (2010) Mol Cell Biol , vol.30 , Issue.6 , pp. 1382-1396
    • Thangavel, S.1    Mendoza-Maldonado, R.2    Tissino, E.3
  • 82
    • 0001743196 scopus 로고
    • An hitherto undescribed familial disease
    • Thomson MS (1923) An hitherto undescribed familial disease. Br J Dermatol 35:455-462
    • (1923) Br J Dermatol , vol.35 , pp. 455-462
    • Thomson, M.S.1
  • 83
    • 2442676334 scopus 로고    scopus 로고
    • Prokaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery
    • Tuteja N, Tuteja R (2004) Prokaryotic and eukaryotic DNA helicases. Essential molecular motor proteins for cellular machinery. Eur J Biochem 271(10):1835-1848
    • (2004) Eur J Biochem , vol.271 , Issue.10 , pp. 1835-1848
    • Tuteja, N.1    Tuteja, R.2
  • 84
    • 84926665965 scopus 로고    scopus 로고
    • RECQL4-related recessive conditions
    • Epstein CJ, Erickson RP, Winshaw-Boris A (eds), 3rd edn. Oxford University Press, Oxford
    • Van Maldergem L, Piard J, Larizza L, Wang LL (2013) RECQL4-related recessive conditions. In: Epstein CJ, Erickson RP, Winshaw-Boris A (eds) Inborn errors of development, 3rd edn. Oxford University Press, Oxford
    • (2013) Inborn errors of development
    • Van Maldergem, L.1    Piard, J.2    Larizza, L.3    Wang, L.L.4
  • 85
    • 32944476196 scopus 로고    scopus 로고
    • Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene
    • Van Maldergem L, Siitonen HA, Jalkh N et al (2006) Revisiting the craniosynostosis-radial ray hypoplasia association: Baller-Gerold syndrome caused by mutations in the RECQL4 gene. J Med Genet 43(2):148-152
    • (2006) J Med Genet , vol.43 , Issue.2 , pp. 148-152
    • Van Maldergem, L.1    Siitonen, H.A.2    Jalkh, N.3
  • 86
    • 79955964176 scopus 로고    scopus 로고
    • High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/beta-catenin target gene, CDC25A
    • Vijayakumar S, Liu G, Rus IA et al (2011) High-frequency canonical Wnt activation in multiple sarcoma subtypes drives proliferation through a TCF/beta-catenin target gene, CDC25A. Cancer Cell 19(5):601-612
    • (2011) Cancer Cell , vol.19 , Issue.5 , pp. 601-612
    • Vijayakumar, S.1    Liu, G.2    Rus, I.A.3
  • 87
    • 0033616679 scopus 로고    scopus 로고
    • DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae
    • Wang H, Elledge SJ (1999) DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 96(7):3824-3829
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.7 , pp. 3824-3829
    • Wang, H.1    Elledge, S.J.2
  • 88
    • 32944462790 scopus 로고    scopus 로고
    • Biology of osteogenic sarcoma
    • Wang LL (2005) Biology of osteogenic sarcoma. Cancer J 11(4):294-305
    • (2005) Cancer J , vol.11 , Issue.4 , pp. 294-305
    • Wang, L.L.1
  • 89
    • 0038288850 scopus 로고    scopus 로고
    • Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome
    • Wang LL, Gannavarapu A, Kozinetz CA et al (2003) Association between osteosarcoma and deleterious mutations in the RECQL4 gene in Rothmund-Thomson syndrome. J Natl Cancer Inst 95(9):669-674
    • (2003) J Natl Cancer Inst , vol.95 , Issue.9 , pp. 669-674
    • Wang, L.L.1    Gannavarapu, A.2    Kozinetz, C.A.3
  • 90
    • 0035934019 scopus 로고    scopus 로고
    • Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients
    • Wang LL, Levy ML, Lewis RA et al (2001) Clinical manifestations in a cohort of 41 Rothmund-Thomson syndrome patients. Am J Med Genet 102(1):11-17
    • (2001) Am J Med Genet , vol.102 , Issue.1 , pp. 11-17
    • Wang, L.L.1    Levy, M.L.2    Lewis, R.A.3
  • 91
    • 33646399211 scopus 로고    scopus 로고
    • RECQL4-defi cient cells are hypersensitive to oxidative stress/damage: Insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome
    • Werner SR, Prahalad AK, Yang J et al (2006) RECQL4-defi cient cells are hypersensitive to oxidative stress/damage: insights for osteosarcoma prevalence and heterogeneity in Rothmund-Thomson syndrome. Biochem Biophys Res Commun 345(1):403-409
    • (2006) Biochem Biophys Res Commun , vol.345 , Issue.1 , pp. 403-409
    • Werner, S.R.1    Prahalad, A.K.2    Yang, J.3
  • 92
    • 33748606377 scopus 로고    scopus 로고
    • The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress
    • Woo LL, Futami K, Shimamoto A et al (2006) The Rothmund-Thomson gene product RECQL4 localizes to the nucleolus in response to oxidative stress. Exp Cell Res 312(17):3443-3457
    • (2006) Exp Cell Res , vol.312 , Issue.17 , pp. 3443-3457
    • Woo, L.L.1    Futami, K.2    Shimamoto, A.3
  • 93
    • 53649102650 scopus 로고    scopus 로고
    • Drosophila homologue of the Rothmund-Thomson syndrome gene: Essential function in DNA replication during development
    • Wu J, Capp C, Feng L et al (2008) Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development. Dev Biol 323(1):130-142
    • (2008) Dev Biol , vol.323 , Issue.1 , pp. 130-142
    • Wu, J.1    Capp, C.2    Feng, L.3
  • 94
    • 84875894854 scopus 로고    scopus 로고
    • The role of telomere biology in cancer
    • Xu L, Li S, Stohr BA (2013) The role of telomere biology in cancer. Annu Rev Pathol 8:49-78
    • (2013) Annu Rev Pathol , vol.8 , pp. 49-78
    • Xu, L.1    Li, S.2    Stohr, B.A.3
  • 95
    • 62049085034 scopus 로고    scopus 로고
    • Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4
    • Xu X, Liu Y (2009) Dual DNA unwinding activities of the Rothmund-Thomson syndrome protein, RECQ4. EMBO J 28(5):568-577
    • (2009) EMBO J , vol.28 , Issue.5 , pp. 568-577
    • Xu, X.1    Liu, Y.2
  • 96
    • 70350573964 scopus 로고    scopus 로고
    • MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication
    • Xu X, Rochette PJ, Feyissa EA et al (2009) MCM10 mediates RECQ4 association with MCM2-7 helicase complex during DNA replication. EMBO J 28(19):3005-3014
    • (2009) EMBO J , vol.28 , Issue.19 , pp. 3005-3014
    • Xu, X.1    Rochette, P.J.2    Feyissa, E.A.3
  • 97
    • 67650679301 scopus 로고    scopus 로고
    • dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila
    • Xu Y, Lei Z, Huang H et al (2009) dRecQ4 is required for DNA synthesis and essential for cell proliferation in Drosophila. PLoS One 4(7):e6107
    • (2009) PLoS One , vol.4 , Issue.7
    • Xu, Y.1    Lei, Z.2    Huang, H.3
  • 98
    • 19544366597 scopus 로고    scopus 로고
    • RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway
    • Yin J, Kwon YT, Varshavsky A et al (2004) RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Hum Mol Genet 13(20):2421-2430
    • (2004) Hum Mol Genet , vol.13 , Issue.20 , pp. 2421-2430
    • Yin, J.1    Kwon, Y.T.2    Varshavsky, A.3
  • 99
    • 15844409553 scopus 로고    scopus 로고
    • Positional cloning of the Werner’s syndrome gene
    • Yu CE, Oshima J, Fu YH et al (1996) Positional cloning of the Werner’s syndrome gene. Science 272(5259):258-262
    • (1996) Science , vol.272 , Issue.5259 , pp. 258-262
    • Yu, C.E.1    Oshima, J.2    Fu, Y.H.3
  • 100
    • 49649103793 scopus 로고    scopus 로고
    • Critical role of notch signaling in osteosarcoma invasion and metastasis
    • Zhang P, Yang Y, Zweidler-McKay PA et al (2008) Critical role of notch signaling in osteosarcoma invasion and metastasis. Clin Cancer Res 14(10):2962-2969
    • (2008) Clin Cancer Res , vol.14 , Issue.10 , pp. 2962-2969
    • Zhang, P.1    Yang, Y.2    Zweidler-McKay, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.