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Volumn 183, Issue 4, 2009, Pages 2659-2668

Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; EPITOPE; ESAT 6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; PEPTIDE FRAGMENT;

EID: 70149092384     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0900947     Document Type: Article
Times cited : (87)

References (44)
  • 1
    • 34250377824 scopus 로고    scopus 로고
    • Tuberculosis vaccines: An update
    • Andersen, P. 2007. Tuberculosis vaccines: an update. Nat. Rev. Microbiol. 5: 484-487.
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 484-487
    • Andersen, P.1
  • 2
    • 46749121412 scopus 로고    scopus 로고
    • Tuberculosis vaccine development: Goals, immunological design, and evaluation
    • Hoft, D. F. 2008. Tuberculosis vaccine development: goals, immunological design, and evaluation. Lancet 372: 164-175.
    • (2008) Lancet , vol.372 , pp. 164-175
    • Hoft, D.F.1
  • 5
    • 0028905679 scopus 로고
    • Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis
    • Boesen, H., B. N. Jensen, T. Wilcke, and P. Andersen. 1995. Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis. Infect. Immun. 63: 1491-1497.
    • (1995) Infect. Immun. , vol.63 , pp. 1491-1497
    • Boesen, H.1    Jensen, B.N.2    Wilcke, T.3    Andersen, P.4
  • 6
    • 0028904655 scopus 로고
    • Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice
    • Andersen, P., A. B. Andersen, A. L. Sorensen, and S. Nagai. 1995. Recall of long-lived immunity to Mycobacterium tuberculosis infection in mice. J. Immunol. 154: 3359-3372.
    • (1995) J. Immunol. , vol.154 , pp. 3359-3372
    • Andersen, P.1    Andersen, A.B.2    Sorensen, A.L.3    Nagai, S.4
  • 7
    • 0034463531 scopus 로고    scopus 로고
    • Multiple epitopes from the Mycobacterium tuberculosis ESAT-6 antigen are recognized by antigen-specific human T cell lines
    • Mustafa, A. S., F. Oftung, H. A. Amoudy, N. M. Madi, A. T. Abal, F. Shaban, I. Rosen Krands, and P. Andersen. 2000. Multiple epitopes from the Mycobacterium tuberculosis ESAT-6 antigen are recognized by antigen-specific human T cell lines. Clin. Infect. Dis. 30(Suppl. 3): S201-S205.
    • (2000) Clin. Infect. Dis. , vol.30 , Issue.SUPPL. 3
    • Mustafa, A.S.1    Oftung, F.2    Amoudy, H.A.3    Madi, N.M.4    Abal, A.T.5    Shaban, F.6    Rosen Krands, I.7    Andersen, P.8
  • 9
    • 0030587887 scopus 로고    scopus 로고
    • Key Epitopes on the ESAT-6 Antigen Recognized in Mice during the Recall of Protective Immunity to Mycobacterium tuberculosis
    • Brandt, L., T. Oettinger, A. Holm, A. B. Andersen, and P. Andersen. 1996. Key epitopes on the ESAT-6 antigen recognized in mice during the recall of protective immunity to Mycobacterium tuberculosis. J. Immunol. 157: 3527-3533. (Pubitemid 126449166)
    • (1996) Journal of Immunology , vol.157 , Issue.8 , pp. 3527-3533
    • Brandt, L.1    Oettinger, T.2    Holm, A.3    Andersen, A.B.4    Andersen, P.5
  • 10
    • 0032211011 scopus 로고    scopus 로고
    • Deceptive imprinting: A cosmopolitan strategy for complicating vaccination
    • Nara, P. L., and R. Garrity. 1998. Deceptive imprinting: a cosmopolitan strategy for complicating vaccination. Vaccine 16: 1780-1787.
    • (1998) Vaccine , vol.16 , pp. 1780-1787
    • Nara, P.L.1    Garrity, R.2
  • 11
    • 0026444130 scopus 로고
    • Clonal dominance: Cause for a limited and failing immune response to HIV-1 infection and vaccination
    • Kohler, H., J. Goudsmit, and P. Nara. 1992. Clonal dominance: cause for a limited and failing immune response to HIV-1 infection and vaccination. J. Acquir. Immune Defic. Syndr. 5: 1158-1168.
    • (1992) J. Acquir. Immune Defic. Syndr. , vol.5 , pp. 1158-1168
    • Kohler, H.1    Goudsmit, J.2    Nara, P.3
  • 12
    • 43949157657 scopus 로고
    • Deceptive imprinting in the immune response against HIV-1
    • Kohler, H., S. Muller, and P. L. Nara. 1994. Deceptive imprinting in the immune response against HIV-1. Immunol. Today 15: 475-478.
    • (1994) Immunol. Today , vol.15 , pp. 475-478
    • Kohler, H.1    Muller, S.2    Nara, P.L.3
  • 13
    • 0345017746 scopus 로고    scopus 로고
    • Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection
    • Sugimoto, K., F. Ikeda, J. Stadanlick, F. A. Nunes, H. J. Alter, and K. M. Chang. 2003. Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection. Hepatology 38: 1437-1448.
    • (2003) Hepatology , vol.38 , pp. 1437-1448
    • Sugimoto, K.1    Ikeda, F.2    Stadanlick, J.3    Nunes, F.A.4    Alter, H.J.5    Chang, K.M.6
  • 17
    • 0034040571 scopus 로고    scopus 로고
    • Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen
    • Olsen, A. W., P. R. Hansen, A. Holm, and P. Andersen. 2000. Efficient protection against Mycobacterium tuberculosis by vaccination with a single subdominant epitope from the ESAT-6 antigen. Eur. J. Immunol. 30: 1724-1732.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 1724-1732
    • Olsen, A.W.1    Hansen, P.R.2    Holm, A.3    Andersen, P.4
  • 18
    • 0026442097 scopus 로고
    • Control of acute infection with lymphocytic choriomeningitis virus in mice that cannot present an immunodominant viral cytotoxic T lymphocyte epitope
    • Gegin, C., and F. Lehmann-Grube. 1992. Control of acute infection with lymphocytic choriomeningitis virus in mice that cannot present an immunodominant viral cytotoxic T lymphocyte epitope. J. Immunol. 149: 3331-3338.
    • (1992) J. Immunol. , vol.149 , pp. 3331-3338
    • Gegin, C.1    Lehmann-Grube, F.2
  • 19
    • 0031134998 scopus 로고    scopus 로고
    • + memory T cells specific for a subdominant epitope following Sendai virus infection
    • + memory T cells specific for a subdominant epitope following Sendai virus infection. J. Immunol. 158: 4301-4309.
    • (1997) J. Immunol. , vol.158 , pp. 4301-4309
    • Cole, G.A.1    Hogg, T.L.2    Coppola, M.A.3    Woodland, D.L.4
  • 21
    • 18644373991 scopus 로고    scopus 로고
    • Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: Efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy
    • Dietrich, J., C. Aagaard, R. Leah, A. W. Olsen, A. Stryhn, T. M. Doherty, and P. Andersen. 2005. Exchanging ESAT6 with TB10.4 in an Ag85B fusion molecule-based tuberculosis subunit vaccine: efficient protection and ESAT6-based sensitive monitoring of vaccine efficacy. J. Immunol. 174: 6332-6339. (Pubitemid 40663826)
    • (2005) Journal of Immunology , vol.174 , Issue.10 , pp. 6332-6339
    • Dietrich, J.1    Aagaard, C.2    Leah, R.3    Olsen, A.W.4    Stryhn, A.5    Doherty, T.M.6    Andersen, P.7
  • 23
    • 34547773111 scopus 로고    scopus 로고
    • Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells
    • Kannanganat, S., C. Ibegbu, L. Chennareddi, H. L. Robinson, and R. R. Amara. 2007. Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells. J. Virol. 81: 8468-8476.
    • (2007) J. Virol. , vol.81 , pp. 8468-8476
    • Kannanganat, S.1    Ibegbu, C.2    Chennareddi, L.3    Robinson, H.L.4    Amara, R.R.5
  • 27
    • 0033081917 scopus 로고    scopus 로고
    • Evolutionary bottlenecks in the agents of tuberculosis, leprosy, and paratuberculosis
    • Frothingham, R. 1999. Evolutionary bottlenecks in the agents of tuberculosis, leprosy, and paratuberculosis. Med. Hypotheses 52: 95-99.
    • (1999) Med. Hypotheses , vol.52 , pp. 95-99
    • Frothingham, R.1
  • 28
    • 30744460678 scopus 로고    scopus 로고
    • Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: Insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set
    • Filliol, I., A. S. Motiwala, M. Cavatore, W. Qi, M. H. Hazbon, M. Bobadilla del Valle, J. Fyfe, L. Garcia-Garcia, N. Rastogi, C. Sola, et al. 2006. Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set. J. Bacteriol. 188: 759-772.
    • (2006) J. Bacteriol. , vol.188 , pp. 759-772
    • Filliol, I.1    Motiwala, A.S.2    Cavatore, M.3    Qi, W.4    Hazbon, M.H.5    Bobadilla Del Valle, M.6    Fyfe, J.7    Garcia-Garcia, L.8    Rastogi, N.9    Sola, C.10
  • 30
    • 0027194738 scopus 로고
    • Immunodominance: A single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants
    • Liu, Z., K. P. Williams, Y. H. Chang, and J. A. Smith. 1993. Immunodominance: a single amino acid substitution within an antigenic site alters intramolecular selection of T cell determinants. J. Immunol. 151: 1852-1858. (Pubitemid 23235658)
    • (1993) Journal of Immunology , vol.151 , Issue.4 , pp. 1852-1858
    • Liu, Z.1    Williams, K.P.2    Chang, Y.-H.3    Smith, J.A.4
  • 34
    • 0002866386 scopus 로고    scopus 로고
    • Dissecting the multifactorial causes of immunodominance in class I- Restricted T cell responses to viruses
    • Chen, W., L. C. Anton, J. R. Bennink, and J. W. Yewdell. 2000. Dissecting the multifactorial causes of immunodominance in class I-restricted T cell responses to viruses. Immunity 12: 83-93. (Pubitemid 30069217)
    • (2000) Immunity , vol.12 , Issue.1 , pp. 83-93
    • Chen, W.1    Anton, L.C.2    Bennink, J.R.3    Yewdell, J.W.4
  • 35
    • 0032211137 scopus 로고    scopus 로고
    • Immunodominance in the CTL response against minor histocompatibility antigens: Interference between responding T cells, rather than with presentation of epitopes
    • Wolpert, E. Z., P. Grufman, J. K. Sandberg, A. Tegnesjo, and K. Karre. 1998. Immunodominance in the CTL response against minor histocompatibility antigens: interference between responding T cells, rather than with presentation of epitopes. J. Immunol. 161: 4499-4505.
    • (1998) J. Immunol. , vol.161 , pp. 4499-4505
    • Wolpert, E.Z.1    Grufman, P.2    Sandberg, J.K.3    Tegnesjo, A.4    Karre, K.5
  • 36
    • 0032999203 scopus 로고    scopus 로고
    • T cell competition for the antigen-presenting cell as a model for immunodominance in the cytotoxic T lymphocyte response against minor histocompatibility antigens
    • Grufman, P., E. Z. Wolpert, J. K. Sandberg, and K. Karre. 1999. T cell competition for the antigen-presenting cell as a model for immunodominance in the cytotoxic T lymphocyte response against minor histocompatibility antigens. Eur. J. Immunol. 29: 2197-2204.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 2197-2204
    • Grufman, P.1    Wolpert, E.Z.2    Sandberg, J.K.3    Karre, K.4
  • 37
    • 0030046476 scopus 로고    scopus 로고
    • Lowering the tone: Mechanisms of immunodominance among epitopes with low affinity for MHC
    • Fairchild, P. J., and D. C. Wraith. 1996. Lowering the tone: mechanisms of immunodominance among epitopes with low affinity for MHC. Immunol. Today 17: 80-85.
    • (1996) Immunol. Today , vol.17 , pp. 80-85
    • Fairchild, P.J.1    Wraith, D.C.2
  • 38
    • 0031568653 scopus 로고    scopus 로고
    • MHC Affinity, Peptide Liberation, T Cell Repertoire, and Immunodominance All Contribute to the Paucity of MHC Class I-Restricted Peptides Recognized by Antiviral CTL
    • Deng, Y., J. W. Yewdell, L. C. Eisenlohr, and J. R. Bennink. 1997. MHC affinity, peptide liberation, T cell repertoire, and immunodominance all contribute to the paucity of MHC class I-restricted peptides recognized by antiviral CTL. J. Immunol. 158: 1507-1515. (Pubitemid 127469502)
    • (1997) Journal of Immunology , vol.158 , Issue.4 , pp. 1507-1515
    • Deng, Y.1    Yewdell, J.W.2    Eisenlohr, L.C.3    Bennink, J.R.4
  • 39
    • 0033557173 scopus 로고    scopus 로고
    • T cell affinity maturation by selective expansion during infection
    • Busch, D. H., and E. G. Pamer. 1999. T cell affinity maturation by selective expansion during infection. J. Exp. Med. 189: 701-710.
    • (1999) J. Exp. Med. , vol.189 , pp. 701-710
    • Busch, D.H.1    Pamer, E.G.2
  • 40
    • 0033118739 scopus 로고    scopus 로고
    • A kinetic basis for T cell receptor repertoire selection during an immune response
    • Savage, P. A., J. J. Boniface, and M. M. Davis. 1999. A kinetic basis for T cell receptor repertoire selection during an immune response. Immunity 10: 485-492.
    • (1999) Immunity , vol.10 , pp. 485-492
    • Savage, P.A.1    Boniface, J.J.2    Davis, M.M.3
  • 42
    • 0036109715 scopus 로고    scopus 로고
    • Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection
    • Santra, S., D. H. Barouch, M. J. Kuroda, J. E. Schmitz, G. R. Krivulka, K. Beaudry, C. I. Lord, M. A. Lifton, L. S. Wyatt, B. Moss, et al. 2002. Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection. J. Virol. 76: 6376-6381.
    • (2002) J. Virol. , vol.76 , pp. 6376-6381
    • Santra, S.1    Barouch, D.H.2    Kuroda, M.J.3    Schmitz, J.E.4    Krivulka, G.R.5    Beaudry, K.6    Lord, C.I.7    Lifton, M.A.8    Wyatt, L.S.9    Moss, B.10
  • 44
    • 67649216110 scopus 로고    scopus 로고
    • Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells
    • Lindenstrom, T., E. M. Agger, K. S. Korsholm, P. A. Darrah, C. Aagaard, R. A. Seder, I. Rosenkrands, and P. Andersen. 2009. Tuberculosis subunit vaccination provides long-term protective immunity characterized by multifunctional CD4 memory T cells. J. Immunol. 182: 8047-8055.
    • (2009) J. Immunol. , vol.182 , pp. 8047-8055
    • Lindenstrom, T.1    Agger, E.M.2    Korsholm, K.S.3    Darrah, P.A.4    Aagaard, C.5    Seder, R.A.6    Rosenkrands, I.7    Andersen, P.8


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