A Broad Profile of Co-Dominant Epitopes Shapes the Peripheral Mycobacterium tuberculosis Specific CD8+ T-Cell Immune Response in South African Patients with Active Tuberculosis

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Axelsson Robertson, Rebecca ^a   Loxton, André G ^b   Walzl, Gerhard ^b   Ehlers, Marthie M ^c   Kock, Marleen M ^c   Zumla, Alimuddin ^d   Maeurer, Markus ^a,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

^c UNIVERSITY OF PRETORIA   (South Africa)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CD45RA ANTIGEN; CHEMOKINE RECEPTOR CCR7; EARLY SECRETORY ANTIGENIC TARGET 6; EPITOPE; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; INTERLEUKIN 7 RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MYCOBACTERIUM TUBERCULOSIS PEPTIDE TB10.4; PROTEIN AG85B; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ANTIGEN STRUCTURE; ARTICLE; BACTERIUM IDENTIFICATION; BINDING AFFINITY; BINDING SITE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; ETHNIC GROUP; GENE FREQUENCY; GENE MAPPING; HUMAN; HUMAN CELL; LUNG TUBERCULOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE HOMING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHENOTYPE; SOUTH AFRICAN;

ADULT; ANTIGENS, BACTERIAL; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES, T-LYMPHOCYTE; FEMALE; HLA-B ANTIGENS; HLA-C ANTIGENS; HUMANS; MALE; MYCOBACTERIUM TUBERCULOSIS; SOUTH AFRICA; TUBERCULOSIS, PULMONARY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84875420686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0058309     Document Type: Article

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