Fisetin Suppresses Lipid Accumulation in Mouse Adipocytic 3T3-L1 Cells by Repressing GLUT4-Mediated Glucose Uptake through Inhibition of mTOR-C/EBPα Signaling

Journal of Agricultural and Food Chemistry

Volumn 63, Issue 20, 2015, Pages 4979-4987

  Watanabe, Marina ^a   Hisatake, Mitsuhiro ^a   Fujimori, Ko ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

adipocytes; C EBP ; fisetin; glucose uptake; mTOR

Indexed keywords

ANTIBIOTICS; BINS; BIOCHEMISTRY; BIOSYNTHESIS; CELLS; CYTOLOGY; FATTY ACIDS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES; GLUCOSE; LIPIDS; MAMMALS; PROTEINS;

ADIPOCYTES; CCAAT/ENHANCER-BINDING PROTEINS; CHROMATIN IMMUNOPRECIPITATION ASSAY; FISETIN; GLUCOSE UPTAKE; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); MTOR; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR;

CELL SIGNALING;

MAMMALIA;

CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, MOUSE; FISETIN; FLAVONOID; GLUCOSE; GLUCOSE TRANSPORTER 4; MTOR PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE;

3T3 CELL LINE; ADIPOCYTE; ADIPOGENESIS; ANIMAL; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; LIPID METABOLISM; METABOLISM; MOUSE; PROMOTER REGION; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

3T3-L1 CELLS; ADIPOCYTES; ADIPOGENESIS; ANIMALS; BIOLOGICAL TRANSPORT; CCAAT-ENHANCER-BINDING PROTEINS; FLAVONOIDS; GENE EXPRESSION REGULATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; LIPID METABOLISM; MICE; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84930216314     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b00821     Document Type: Article

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