Andrographolide derivative AL-1 improves insulin resistance through down-regulation of NF-κB signalling pathway

British Journal of Pharmacology

Volumn 172, Issue 12, 2015, Pages 3151-3158

  Li, Yongmei ^a   Yan, Hui ^a   Zhang, Zaijun ^a   Zhang, Gaoxiao ^a   Sun, Yewei ^a   Yu, Pei ^a   Wang, Yuqiang ^a   Xu, Lipeng ^a  

^a JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AL 1; ANDROGRAPHOLIDE; ANTIDIABETIC AGENT; GLIBENCLAMIDE; GLUCOSE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SYNAPTOTAGMIN I; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; DITERPENE; REACTIVE OXYGEN METABOLITE; STREPTOZOCIN; THIOCTIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; CELL DAMAGE; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; DRUG DOSE COMPARISON; DRUG MECHANISM; GLUCOSE BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; INSULINOMA CELL LINE; LIPID BLOOD LEVEL; LIPID DIET; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; ANDROGRAPHIS; ANIMAL; CHEMISTRY; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DOSE RESPONSE; DRUG EFFECTS; INFLAMMATION; INSULINOMA; METABOLISM; PANCREAS ISLET; PANCREAS TUMOR; PATHOLOGY; SPRAGUE DAWLEY RAT;

ANDROGRAPHIS; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; HYPOGLYCEMIC AGENTS; INFLAMMATION; INSULIN RESISTANCE; INSULINOMA; ISLETS OF LANGERHANS; MALE; NF-KAPPA B; PANCREATIC NEOPLASMS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STREPTOZOCIN; THIOCTIC ACID;

EID: 84930199046     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13118     Document Type: Article

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