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Volumn 172, Issue 12, 2015, Pages 3177-3188

Antidepressants but not antipsychotics have antiepileptogenic effects with limited effects on comorbid depressive-like behaviour in the WAG/Rij rat model of absence epilepsy

Author keywords

[No Author keywords available]

Indexed keywords

DULOXETINE; FLUOXETINE; HALOPERIDOL; QUETIAPINE; RISPERIDONE; ANTIDEPRESSANT AGENT; NEUROLEPTIC AGENT;

EID: 84930195257     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13121     Document Type: Article
Times cited : (49)

References (98)
  • 4
    • 84899491127 scopus 로고    scopus 로고
    • Long-term seizure remission in childhood absence epilepsy: Might initial treatment matter?
    • Berg AT, Levy SR, Testa FM, Blumenfeld H, (2014). Long-term seizure remission in childhood absence epilepsy: might initial treatment matter? Epilepsia 55: 551-557.
    • (2014) Epilepsia , vol.55 , pp. 551-557
    • Berg, A.T.1    Levy, S.R.2    Testa, F.M.3    Blumenfeld, H.4
  • 5
    • 39749159858 scopus 로고    scopus 로고
    • Early treatment suppresses the development of spike-wave epilepsy in a rat model
    • Blumenfeld H, Klein JP, Schridde U, Vestal M, Rice T, Khera DS, et al. (2008). Early treatment suppresses the development of spike-wave epilepsy in a rat model. Epilepsia 49: 400-409.
    • (2008) Epilepsia , vol.49 , pp. 400-409
    • Blumenfeld, H.1    Klein, J.P.2    Schridde, U.3    Vestal, M.4    Rice, T.5    Khera, D.S.6
  • 6
    • 15044361698 scopus 로고    scopus 로고
    • The serotonin syndrome
    • Boyer EW, Shannon M, (2005). The serotonin syndrome. N Engl J Med 352: 1112-1120.
    • (2005) N Engl J Med , vol.352 , pp. 1112-1120
    • Boyer, E.W.1    Shannon, M.2
  • 7
    • 84888201969 scopus 로고    scopus 로고
    • Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy
    • Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, et al. (2013). Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. Epilepsia 54 (Suppl. 4): 44-60.
    • (2013) Epilepsia , vol.54 , pp. 44-60
    • Brooks-Kayal, A.R.1    Bath, K.G.2    Berg, A.T.3    Galanopoulou, A.S.4    Holmes, G.L.5    Jensen, F.E.6
  • 9
    • 0035217806 scopus 로고    scopus 로고
    • Dopamine characteristics in rat genotypes with distinct susceptibility to epileptic activity: Apomorphine-induced stereotyped gnawing and novelty/amphetamine-induced locomotor stimulation
    • de Bruin NM, van Luijtelaar EL, Cools AR, Ellenbroek BA, (2001). Dopamine characteristics in rat genotypes with distinct susceptibility to epileptic activity: apomorphine-induced stereotyped gnawing and novelty/amphetamine-induced locomotor stimulation. Behav Pharmacol 12: 517-525.
    • (2001) Behav Pharmacol , vol.12 , pp. 517-525
    • De Bruin, N.M.1    Van Luijtelaar, E.L.2    Cools, A.R.3    Ellenbroek, B.A.4
  • 10
    • 55449088293 scopus 로고    scopus 로고
    • Childhood absence epilepsy: Behavioral, cognitive, and linguistic comorbidities
    • Caplan R, Siddarth P, Stahl L, Lanphier E, Vona P, Gurbani S, et al. (2008). Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities. Epilepsia 49: 1838-1846.
    • (2008) Epilepsia , vol.49 , pp. 1838-1846
    • Caplan, R.1    Siddarth, P.2    Stahl, L.3    Lanphier, E.4    Vona, P.5    Gurbani, S.6
  • 11
    • 84875206814 scopus 로고    scopus 로고
    • Antidepressant therapy in epilepsy: Can treating the comorbidities affect the underlying disorder?
    • Cardamone L, Salzberg MR, O'Brien TJ, Jones NC, (2013). Antidepressant therapy in epilepsy: can treating the comorbidities affect the underlying disorder? Br J Pharmacol 168: 1531-1554.
    • (2013) Br J Pharmacol , vol.168 , pp. 1531-1554
    • Cardamone, L.1    Salzberg, M.R.2    O'Brien, T.J.3    Jones, N.C.4
  • 12
    • 0028299241 scopus 로고
    • Spontaneous recurrent seizures in rats: Amino acid and monoamine determination in the hippocampus
    • Cavalheiro EA, Fernandes MJ, Turski L, Naffah-Mazzacoratti MG, (1994). Spontaneous recurrent seizures in rats: amino acid and monoamine determination in the hippocampus. Epilepsia 35: 1-11.
    • (1994) Epilepsia , vol.35 , pp. 1-11
    • Cavalheiro, E.A.1    Fernandes, M.J.2    Turski, L.3    Naffah-Mazzacoratti, M.G.4
  • 13
    • 84880557831 scopus 로고    scopus 로고
    • A systematic review of the evidence for the treatment of acute depression in bipolar i disorder
    • Cerullo MA, Strakowski SM, (2013). A systematic review of the evidence for the treatment of acute depression in bipolar I disorder. CNS Spectr 18: 199-208.
    • (2013) CNS Spectr , vol.18 , pp. 199-208
    • Cerullo, M.A.1    Strakowski, S.M.2
  • 14
    • 0026564595 scopus 로고
    • Linear pharmacokinetics of haloperidol in the rat
    • Cheng YF, Paalzow LK, (1992). Linear pharmacokinetics of haloperidol in the rat. Biopharm Drug Dispos 13: 69-76.
    • (1992) Biopharm Drug Dispos , vol.13 , pp. 69-76
    • Cheng, Y.F.1    Paalzow, L.K.2
  • 15
    • 79957951224 scopus 로고    scopus 로고
    • Preclinical activity profile of alpha-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy
    • Citraro R, Scicchitano F, De Fazio S, Raggio R, Mainardi P, Perucca E, et al. (2011). Preclinical activity profile of alpha-lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. Epilepsy Res 95: 60-69.
    • (2011) Epilepsy Res , vol.95 , pp. 60-69
    • Citraro, R.1    Scicchitano, F.2    De Fazio, S.3    Raggio, R.4    Mainardi, P.5    Perucca, E.6
  • 16
    • 84883284124 scopus 로고    scopus 로고
    • CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations
    • Citraro R, Russo E, Ngomba RT, Nicoletti F, Scicchitano F, Whalley BJ, et al. (2013a). CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations. Epilepsy Res 106: 74-82.
    • (2013) Epilepsy Res , vol.106 , pp. 74-82
    • Citraro, R.1    Russo, E.2    Ngomba, R.T.3    Nicoletti, F.4    Scicchitano, F.5    Whalley, B.J.6
  • 17
    • 84875265975 scopus 로고    scopus 로고
    • Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-alpha receptor activation in a genetic model of absence epilepsy
    • Citraro R, Russo E, Scicchitano F, van Rijn CM, Cosco D, Avagliano C, et al. (2013b). Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-alpha receptor activation in a genetic model of absence epilepsy. Neuropharmacology 69: 115-126.
    • (2013) Neuropharmacology , vol.69 , pp. 115-126
    • Citraro, R.1    Russo, E.2    Scicchitano, F.3    Van Rijn, C.M.4    Cosco, D.5    Avagliano, C.6
  • 18
    • 84905503346 scopus 로고    scopus 로고
    • Protective effects of some statins on epileptogenesis and depressive-like behavior in WAG/Rij rats, a genetic animal model of absence epilepsy
    • Citraro R, Chimirri S, Aiello R, Gallelli L, Trimboli F, Britti D, et al. (2014). Protective effects of some statins on epileptogenesis and depressive-like behavior in WAG/Rij rats, a genetic animal model of absence epilepsy. Epilepsia 55: 1284-1291.
    • (2014) Epilepsia , vol.55 , pp. 1284-1291
    • Citraro, R.1    Chimirri, S.2    Aiello, R.3    Gallelli, L.4    Trimboli, F.5    Britti, D.6
  • 19
    • 84930210412 scopus 로고    scopus 로고
    • Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats
    • Citraro R, Leo A, Aiello R, Pugliese M, Russo E, De Sarro G, (2015). Comparative analysis of the treatment of chronic antipsychotic drugs on epileptic susceptibility in genetically epilepsy-prone rats. Neurother 12: 250-262.
    • (2015) Neurother , vol.12 , pp. 250-262
    • Citraro, R.1    Leo, A.2    Aiello, R.3    Pugliese, M.4    Russo, E.5    De Sarro, G.6
  • 20
    • 53049104980 scopus 로고    scopus 로고
    • Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy
    • Ciumas C, Wahlin TB, Jucaite A, Lindstrom P, Halldin C, Savic I, (2008). Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy. Neurology 71: 788-794.
    • (2008) Neurology , vol.71 , pp. 788-794
    • Ciumas, C.1    Wahlin, T.B.2    Jucaite, A.3    Lindstrom, P.4    Halldin, C.5    Savic, I.6
  • 21
    • 84899707460 scopus 로고    scopus 로고
    • Schizophrenia: Mechanism of action of current and novel treatments
    • Correll CU, Kane JM, (2014). Schizophrenia: mechanism of action of current and novel treatments. J Clin Psychiatry 75: 347-348.
    • (2014) J Clin Psychiatry , vol.75 , pp. 347-348
    • Correll, C.U.1    Kane, J.M.2
  • 22
    • 0034648731 scopus 로고    scopus 로고
    • Dopamine in the striatum modulates seizures in a genetic model of absence epilepsy in the rat
    • Deransart C, Riban V, Le B, Marescaux C, Depaulis A, (2000). Dopamine in the striatum modulates seizures in a genetic model of absence epilepsy in the rat. Neuroscience 100: 335-344.
    • (2000) Neuroscience , vol.100 , pp. 335-344
    • Deransart, C.1    Riban, V.2    Le, B.3    Marescaux, C.4    Depaulis, A.5
  • 23
    • 0035914197 scopus 로고    scopus 로고
    • Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat
    • Deransart C, Landwehrmeyer GB, Feuerstein TJ, Lucking CH, (2001). Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat. Brain Res Mol Brain Res 94: 166-177.
    • (2001) Brain Res Mol Brain Res , vol.94 , pp. 166-177
    • Deransart, C.1    Landwehrmeyer, G.B.2    Feuerstein, T.J.3    Lucking, C.H.4
  • 24
    • 84875859244 scopus 로고    scopus 로고
    • Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy
    • Dezsi G, Ozturk E, Stanic D, Powell KL, Blumenfeld H, O'Brien TJ, et al. (2013). Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy. Epilepsia 54: 635-643.
    • (2013) Epilepsia , vol.54 , pp. 635-643
    • Dezsi, G.1    Ozturk, E.2    Stanic, D.3    Powell, K.L.4    Blumenfeld, H.5    O'Brien, T.J.6
  • 25
    • 83455217396 scopus 로고    scopus 로고
    • The effect of haloperidol on maternal behavior in WAG/Rij rats and its consequences in the offspring
    • Dobryakova YV, Dubynin VA, Luijtelaar G, (2011). The effect of haloperidol on maternal behavior in WAG/Rij rats and its consequences in the offspring. Acta Neurobiol Exp (Wars) 71: 339-347.
    • (2011) Acta Neurobiol Exp (Wars) , vol.71 , pp. 339-347
    • Dobryakova, Y.V.1    Dubynin, V.A.2    Luijtelaar, G.3
  • 26
    • 0038083311 scopus 로고    scopus 로고
    • The anticonvulsant effect of citalopram as an indirect evidence of serotonergic impairment in human epileptogenesis
    • Favale E, Audenino D, Cocito L, Albano C, (2003). The anticonvulsant effect of citalopram as an indirect evidence of serotonergic impairment in human epileptogenesis. Seizure 12: 316-318.
    • (2003) Seizure , vol.12 , pp. 316-318
    • Favale, E.1    Audenino, D.2    Cocito, L.3    Albano, C.4
  • 27
    • 0033548027 scopus 로고    scopus 로고
    • A serotonin-1A receptor agonist and an N-methyl-D-aspartate receptor antagonist oppose each others effects in a genetic rat epilepsy model
    • Filakovszky J, Gerber K, Bagdy G, (1999). A serotonin-1A receptor agonist and an N-methyl-D-aspartate receptor antagonist oppose each others effects in a genetic rat epilepsy model. Neurosci Lett 261: 89-92.
    • (1999) Neurosci Lett , vol.261 , pp. 89-92
    • Filakovszky, J.1    Gerber, K.2    Bagdy, G.3
  • 28
    • 0032487145 scopus 로고    scopus 로고
    • The 5-HT1A agonist 8-OH-DPAT increases the number of spike-wave discharges in a genetic rat model of absence epilepsy
    • Gerber K, Filakovszky J, Halasz P, Bagdy G, (1998). The 5-HT1A agonist 8-OH-DPAT increases the number of spike-wave discharges in a genetic rat model of absence epilepsy. Brain Res 807: 243-245.
    • (1998) Brain Res , vol.807 , pp. 243-245
    • Gerber, K.1    Filakovszky, J.2    Halasz, P.3    Bagdy, G.4
  • 29
    • 77952592440 scopus 로고    scopus 로고
    • Is epilepsy a preventable disorder? New evidence from animal models
    • Giblin KA, Blumenfeld H, (2010). Is epilepsy a preventable disorder? New evidence from animal models. Neuroscientist 16: 253-275.
    • (2010) Neuroscientist , vol.16 , pp. 253-275
    • Giblin, K.A.1    Blumenfeld, H.2
  • 31
    • 1842608901 scopus 로고    scopus 로고
    • Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy
    • Graf M, Jakus R, Kantor S, Levay G, Bagdy G, (2004). Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy. Neurosci Lett 359: 45-48.
    • (2004) Neurosci Lett , vol.359 , pp. 45-48
    • Graf, M.1    Jakus, R.2    Kantor, S.3    Levay, G.4    Bagdy, G.5
  • 32
    • 84875267737 scopus 로고    scopus 로고
    • Should antidepressant drugs of the selective serotonin reuptake inhibitor family be tested as antiepileptic drugs?
    • Hamid H, Kanner AM, (2013). Should antidepressant drugs of the selective serotonin reuptake inhibitor family be tested as antiepileptic drugs? Epilepsy Behav 26: 261-265.
    • (2013) Epilepsy Behav , vol.26 , pp. 261-265
    • Hamid, H.1    Kanner, A.M.2
  • 34
    • 80051546513 scopus 로고    scopus 로고
    • Depression in epilepsy: A critical review from a clinical perspective
    • Hoppe C, Elger CE, (2011). Depression in epilepsy: a critical review from a clinical perspective. Nat Rev Neurol 7: 462-472.
    • (2011) Nat Rev Neurol , vol.7 , pp. 462-472
    • Hoppe, C.1    Elger, C.E.2
  • 35
    • 84859422726 scopus 로고    scopus 로고
    • Preclinical antiepileptic actions of selective serotonin reuptake inhibitors - Implications for clinical trial design
    • Igelstrom KM, (2012). Preclinical antiepileptic actions of selective serotonin reuptake inhibitors-implications for clinical trial design. Epilepsia 53: 596-605.
    • (2012) Epilepsia , vol.53 , pp. 596-605
    • Igelstrom, K.M.1
  • 36
    • 0018885338 scopus 로고
    • Epileptogenic side effects of psychotropic drugs. Practical recommendations
    • Itil TM, Soldatos C, (1980). Epileptogenic side effects of psychotropic drugs. Practical recommendations. JAMA 244: 1460-1463.
    • (1980) JAMA , vol.244 , pp. 1460-1463
    • Itil, T.M.1    Soldatos, C.2
  • 37
    • 0842299485 scopus 로고    scopus 로고
    • 5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy
    • Jakus R, Graf M, Juhasz G, Gerber K, Levay G, Halasz P, et al. (2003). 5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy. Exp Neurol 184: 964-972.
    • (2003) Exp Neurol , vol.184 , pp. 964-972
    • Jakus, R.1    Graf, M.2    Juhasz, G.3    Gerber, K.4    Levay, G.5    Halasz, P.6
  • 38
    • 16344385331 scopus 로고    scopus 로고
    • Should neurologists be trained to recognize and treat comorbid depression of neurologic disorders? Yes
    • Kanner AM, (2005). Should neurologists be trained to recognize and treat comorbid depression of neurologic disorders? Yes. Epilepsy Behav 6: 303-311.
    • (2005) Epilepsy Behav , vol.6 , pp. 303-311
    • Kanner, A.M.1
  • 39
    • 78651268507 scopus 로고    scopus 로고
    • Depression and epilepsy: A bidirectional relation?
    • Kanner AM, (2011). Depression and epilepsy: a bidirectional relation? Epilepsia 52 (Suppl. 1): 21-27.
    • (2011) Epilepsia , vol.52 , pp. 21-27
    • Kanner, A.M.1
  • 40
    • 84869121865 scopus 로고    scopus 로고
    • Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders?
    • Kanner AM, (2012). Can neurobiological pathogenic mechanisms of depression facilitate the development of seizure disorders? Lancet Neurol 11: 1093-1102.
    • (2012) Lancet Neurol , vol.11 , pp. 1093-1102
    • Kanner, A.M.1
  • 41
    • 84861409043 scopus 로고    scopus 로고
    • Depression and epilepsy: Epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence
    • Kanner AM, Schachter SC, Barry JJ, Hesdorffer DC, Mula M, Trimble M, et al. (2012). Depression and epilepsy: epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence. Epilepsy Behav 24: 156-168.
    • (2012) Epilepsy Behav , vol.24 , pp. 156-168
    • Kanner, A.M.1    Schachter, S.C.2    Barry, J.J.3    Hesdorffer, D.C.4    Mula, M.5    Trimble, M.6
  • 42
    • 0037405871 scopus 로고    scopus 로고
    • Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: A suggested solution based on in vivo occupancy
    • Kapur S, VanderSpek SC, Brownlee BA, Nobrega JN, (2003). Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy. J Pharmacol Exp Ther 305: 625-631.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 625-631
    • Kapur, S.1    Vanderspek, S.C.2    Brownlee, B.A.3    Nobrega, J.N.4
  • 43
    • 80255138221 scopus 로고    scopus 로고
    • International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy
    • Kerr MP, Mensah S, Besag F, de Toffol B, Ettinger A, Kanemoto K, et al. (2011). International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy. Epilepsia 52: 2133-2138.
    • (2011) Epilepsia , vol.52 , pp. 2133-2138
    • Kerr, M.P.1    Mensah, S.2    Besag, F.3    De Toffol, B.4    Ettinger, A.5    Kanemoto, K.6
  • 45
    • 0020545199 scopus 로고
    • The role of different types of adrenergic receptors in pentylenetetrazol-induced seizures and the effect of di-n-propylacetate in the rat
    • Lazarova M, Bendotti C, Samanin R, (1983). The role of different types of adrenergic receptors in pentylenetetrazol-induced seizures and the effect of di-n-propylacetate in the rat. Psychopharmacology (Berl) 81: 177-182.
    • (1983) Psychopharmacology (Berl) , vol.81 , pp. 177-182
    • Lazarova, M.1    Bendotti, C.2    Samanin, R.3
  • 47
    • 84884359677 scopus 로고    scopus 로고
    • Serotonergic receptor mechanisms underlying antidepressant-like action in the progesterone withdrawal model of hormonally induced depression in rats
    • Li Y, Raaby KF, Sanchez C, Gulinello M, (2013). Serotonergic receptor mechanisms underlying antidepressant-like action in the progesterone withdrawal model of hormonally induced depression in rats. Behav Brain Res 256: 520-528.
    • (2013) Behav Brain Res , vol.256 , pp. 520-528
    • Li, Y.1    Raaby, K.F.2    Sanchez, C.3    Gulinello, M.4
  • 48
    • 0034141630 scopus 로고    scopus 로고
    • Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test
    • Lopez-Rubalcava C, Lucki I, (2000). Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test. Neuropsychopharmacology 22: 191-199.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 191-199
    • Lopez-Rubalcava, C.1    Lucki, I.2
  • 49
    • 84893288265 scopus 로고    scopus 로고
    • Progress and outlooks in a genetic absence epilepsy model (WAG/Rij)
    • van Luijtelaar G, Zobeiri M, (2014). Progress and outlooks in a genetic absence epilepsy model (WAG/Rij). Curr Med Chem 21: 704-721.
    • (2014) Curr Med Chem , vol.21 , pp. 704-721
    • Van Luijtelaar, G.1    Zobeiri, M.2
  • 50
    • 79958025263 scopus 로고    scopus 로고
    • On the origin and suddenness of absences in genetic absence models
    • van Luijtelaar G, Sitnikova E, Littjohann A, (2011). On the origin and suddenness of absences in genetic absence models. Clin EEG Neurosci 42: 83-97.
    • (2011) Clin EEG Neurosci , vol.42 , pp. 83-97
    • Van Luijtelaar, G.1    Sitnikova, E.2    Littjohann, A.3
  • 51
    • 84909633426 scopus 로고    scopus 로고
    • Animal models of absence epilepsies: What do they model and do sex and sex hormones matter?
    • van Luijtelaar G, Onat FY, Gallagher MJ, (2014). Animal models of absence epilepsies: what do they model and do sex and sex hormones matter? Neurobiol Dis 72 (Pt B): 167-179.
    • (2014) Neurobiol Dis , vol.72 , pp. 167-179
    • Van Luijtelaar, G.1    Onat, F.Y.2    Gallagher, M.J.3
  • 52
    • 0038147541 scopus 로고    scopus 로고
    • Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression
    • Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, et al. (2003). Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biol Psychiatry 53: 707-742.
    • (2003) Biol Psychiatry , vol.53 , pp. 707-742
    • Manji, H.K.1    Quiroz, J.A.2    Sporn, J.3    Payne, J.L.4    Denicoff, K.5    Gray N, A.6
  • 54
    • 84887729168 scopus 로고    scopus 로고
    • Omega-3 fatty acid deficiency does not alter the effects of chronic fluoxetine treatment on central serotonin turnover or behavior in the forced swim test in female rats
    • 114115
    • McNamara RK, Able JA, Liu Y, Jandacek R, Rider T, Tso P, et al. (2013). Omega-3 fatty acid deficiency does not alter the effects of chronic fluoxetine treatment on central serotonin turnover or behavior in the forced swim test in female rats. Pharmacol Biochem Behav 114-115: 1-8.
    • (2013) Pharmacol Biochem Behav , pp. 1-8
    • McNamara, R.K.1    Able, J.A.2    Liu, Y.3    Jandacek, R.4    Rider, T.5    Tso, P.6
  • 55
    • 0035903035 scopus 로고    scopus 로고
    • Electrophysiological and pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats
    • Midzianovskaia IS, Kuznetsova GD, Coenen AM, Spiridonov AM, van Luijtelaar EL, (2001). Electrophysiological and pharmacological characteristics of two types of spike-wave discharges in WAG/Rij rats. Brain Res 911: 62-70.
    • (2001) Brain Res , vol.911 , pp. 62-70
    • Midzianovskaia, I.S.1    Kuznetsova, G.D.2    Coenen, A.M.3    Spiridonov, A.M.4    Van Luijtelaar, E.L.5
  • 56
    • 0028118728 scopus 로고
    • Role of norepinephrine in forebrain and brainstem seizures: Chemical lesioning of locus ceruleus with DSP4
    • Mishra PK, Burger RL, Bettendorf AF, Browning RA, Jobe PC, (1994). Role of norepinephrine in forebrain and brainstem seizures: chemical lesioning of locus ceruleus with DSP4. Exp Neurol 125: 58-64.
    • (1994) Exp Neurol , vol.125 , pp. 58-64
    • Mishra, P.K.1    Burger, R.L.2    Bettendorf, A.F.3    Browning, R.A.4    Jobe, P.C.5
  • 57
    • 0036459983 scopus 로고    scopus 로고
    • Quetiapine: Preclinical studies, pharmacokinetics, drug interactions, and dosing
    • Nemeroff CB, Kinkead B, Goldstein J, (2002). Quetiapine: preclinical studies, pharmacokinetics, drug interactions, and dosing. J Clin Psychiatry 63 (Suppl. 13): 5-11.
    • (2002) J Clin Psychiatry , vol.63 , pp. 5-11
    • Nemeroff, C.B.1    Kinkead, B.2    Goldstein, J.3
  • 58
    • 77957273984 scopus 로고    scopus 로고
    • Animal models of neuropsychiatric disorders
    • Nestler EJ, Hyman SE, (2010). Animal models of neuropsychiatric disorders. Nat Neurosci 13: 1161-1169.
    • (2010) Nat Neurosci , vol.13 , pp. 1161-1169
    • Nestler, E.J.1    Hyman, S.E.2
  • 59
    • 0027499341 scopus 로고
    • Relationship between antidepressant response and plasma concentrations of fluoxetine and norfluoxetine
    • Norman TR, Gupta RK, Burrows GD, Parker G, Judd FK, (1993). Relationship between antidepressant response and plasma concentrations of fluoxetine and norfluoxetine. Int Clin Psychopharmacol 8: 25-29.
    • (1993) Int Clin Psychopharmacol , vol.8 , pp. 25-29
    • Norman, T.R.1    Gupta, R.K.2    Burrows, G.D.3    Parker, G.4    Judd, F.K.5
  • 60
    • 0024342291 scopus 로고
    • Noradrenaline and serotonin selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current
    • Pape HC, McCormick DA, (1989). Noradrenaline and serotonin selectively modulate thalamic burst firing by enhancing a hyperpolarization-activated cation current. Nature 340: 715-718.
    • (1989) Nature , vol.340 , pp. 715-718
    • Pape, H.C.1    McCormick, D.A.2
  • 61
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • NC-IUPHAR DATABASE ISSUE
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR. (2014) The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl Acids Res 42 (Database Issue): D1098-D1106.
    • (2014) Nucl Acids Res , vol.42 , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 62
    • 0034858638 scopus 로고    scopus 로고
    • The management of refractory idiopathic epilepsies
    • Perucca E, (2001). The management of refractory idiopathic epilepsies. Epilepsia 42 (Suppl. 3): 31-35.
    • (2001) Epilepsia , vol.42 , pp. 31-35
    • Perucca, E.1
  • 64
    • 84899476404 scopus 로고    scopus 로고
    • Past and present definitions of epileptogenesis and its biomarkers
    • Pitkanen A, Engel J Jr, (2014). Past and present definitions of epileptogenesis and its biomarkers. Neurother 11: 231-241.
    • (2014) Neurother , vol.11 , pp. 231-241
    • Pitkanen, A.1    Engel, Jr.J.2
  • 66
    • 0027502462 scopus 로고
    • Anticonvulsant effect of fluoxetine on focally evoked limbic motor seizures in rats
    • Prendiville S, Gale K, (1993). Anticonvulsant effect of fluoxetine on focally evoked limbic motor seizures in rats. Epilepsia 34: 381-384.
    • (1993) Epilepsia , vol.34 , pp. 381-384
    • Prendiville, S.1    Gale, K.2
  • 67
    • 84861801858 scopus 로고    scopus 로고
    • Epilepsy and psychiatric comorbidity: A nationally representative population-based study
    • Rai D, Kerr MP, McManus S, Jordanova V, Lewis G, Brugha TS, (2012). Epilepsy and psychiatric comorbidity: a nationally representative population-based study. Epilepsia 53: 1095-1103.
    • (2012) Epilepsia , vol.53 , pp. 1095-1103
    • Rai, D.1    Kerr, M.P.2    McManus, S.3    Jordanova, V.4    Lewis, G.5    Brugha, T.S.6
  • 68
    • 0031931974 scopus 로고    scopus 로고
    • Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test
    • Reneric JP, Lucki I, (1998). Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test. Psychopharmacology (Berl) 136: 190-197.
    • (1998) Psychopharmacology (Berl) , vol.136 , pp. 190-197
    • Reneric, J.P.1    Lucki, I.2
  • 69
    • 78651321207 scopus 로고    scopus 로고
    • The serotonin axis: Shared mechanisms in seizures, depression, and SUDEP
    • Richerson GB, Buchanan GF, (2011). The serotonin axis: shared mechanisms in seizures, depression, and SUDEP. Epilepsia 52 (Suppl. 1): 28-38.
    • (2011) Epilepsia , vol.52 , pp. 28-38
    • Richerson, G.B.1    Buchanan, G.F.2
  • 70
    • 77955340670 scopus 로고    scopus 로고
    • Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy
    • Russo E, Citraro R, Scicchitano F, De Fazio S, Di Paola ED, Constanti A, et al. (2010). Comparison of the antiepileptogenic effects of an early long-term treatment with ethosuximide or levetiracetam in a genetic animal model of absence epilepsy. Epilepsia 51: 1560-1569.
    • (2010) Epilepsia , vol.51 , pp. 1560-1569
    • Russo, E.1    Citraro, R.2    Scicchitano, F.3    De Fazio, S.4    Di Paola, E.D.5    Constanti, A.6
  • 71
    • 79960010846 scopus 로고    scopus 로고
    • Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model
    • Russo E, Citraro R, Scicchitano F, De Fazio S, Perrotta I, Di Paola ED, et al. (2011a). Effects of early long-term treatment with antiepileptic drugs on development of seizures and depressive-like behavior in a rat genetic absence epilepsy model. Epilepsia 52: 1341-1350.
    • (2011) Epilepsia , vol.52 , pp. 1341-1350
    • Russo, E.1    Citraro, R.2    Scicchitano, F.3    De Fazio, S.4    Perrotta, I.5    Di Paola, E.D.6
  • 72
    • 80052405638 scopus 로고    scopus 로고
    • Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity
    • Russo E, Citraro R, Scicchitano F, Urzino A, Marra R, Rispoli V, et al. (2011b). Vigabatrin has antiepileptogenic and antidepressant effects in an animal model of epilepsy and depression comorbidity. Behav Brain Res 225: 373-376.
    • (2011) Behav Brain Res , vol.225 , pp. 373-376
    • Russo, E.1    Citraro, R.2    Scicchitano, F.3    Urzino, A.4    Marra, R.5    Rispoli, V.6
  • 73
    • 84867283591 scopus 로고    scopus 로고
    • Protective activity of alpha-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis
    • Russo E, Scicchitano F, Citraro R, Aiello R, Camastra C, Mainardi P, et al. (2012). Protective activity of alpha-lactoalbumin (ALAC), a whey protein rich in tryptophan, in rodent models of epileptogenesis. Neuroscience 226: 282-288.
    • (2012) Neuroscience , vol.226 , pp. 282-288
    • Russo, E.1    Scicchitano, F.2    Citraro, R.3    Aiello, R.4    Camastra, C.5    Mainardi, P.6
  • 74
    • 84866413103 scopus 로고    scopus 로고
    • Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity
    • Russo E, Citraro R, Davoli A, Gallelli L, Di Paola ED, De Sarro G, (2013a). Ameliorating effects of aripiprazole on cognitive functions and depressive-like behavior in a genetic rat model of absence epilepsy and mild-depression comorbidity. Neuropharmacology 64: 371-379.
    • (2013) Neuropharmacology , vol.64 , pp. 371-379
    • Russo, E.1    Citraro, R.2    Davoli, A.3    Gallelli, L.4    Di Paola, E.D.5    De Sarro, G.6
  • 75
    • 84875258395 scopus 로고    scopus 로고
    • MTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy
    • Russo E, Citraro R, Donato G, Camastra C, Iuliano R, Cuzzocrea S, et al. (2013b). mTOR inhibition modulates epileptogenesis, seizures and depressive behavior in a genetic rat model of absence epilepsy. Neuropharmacology 69: 25-36.
    • (2013) Neuropharmacology , vol.69 , pp. 25-36
    • Russo, E.1    Citraro, R.2    Donato, G.3    Camastra, C.4    Iuliano, R.5    Cuzzocrea, S.6
  • 76
    • 0033869471 scopus 로고    scopus 로고
    • Variation of the genes encoding the human glutamate EAAT2, serotonin and dopamine transporters and Susceptibility to idiopathic generalized epilepsy
    • Sander T, Berlin W, Ostapowicz A, Samochowiec J, Gscheidel N, Hoehe MR, (2000). Variation of the genes encoding the human glutamate EAAT2, serotonin and dopamine transporters and Susceptibility to idiopathic generalized epilepsy. Epilepsy Res 41: 75-81.
    • (2000) Epilepsy Res , vol.41 , pp. 75-81
    • Sander, T.1    Berlin, W.2    Ostapowicz, A.3    Samochowiec, J.4    Gscheidel, N.5    Hoehe, M.R.6
  • 77
    • 84892955609 scopus 로고    scopus 로고
    • Neurobiology of depression as a comorbidity of epilepsy
    • Noebels J.L. Avoli M. Rogawski M.A. Olsen R.W. Delgado-Escueta A.V. (eds). 4th edn. Oxford University Press: Bethesda, MD
    • Sankar R, Mazarati A, (2012). Neurobiology of depression as a comorbidity of epilepsy. In:, Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, (eds). Jasper's Basic Mechanisms of the Epilepsies, 4th edn. Oxford University Press: Bethesda, MD.
    • (2012) Jasper's Basic Mechanisms of the Epilepsies
    • Sankar, R.1    Mazarati, A.2
  • 78
    • 77954619992 scopus 로고    scopus 로고
    • Effect of selective serotonin reuptake inhibitor fluoxetine on symptoms of depression-like behavior in WAG/Rij rats
    • Sarkisova K, Folomkina AA, (2010). [Effect of selective serotonin reuptake inhibitor fluoxetine on symptoms of depression-like behavior in WAG/Rij rats]. Zh Vyssh Nerv Deiat Im I P Pavlova 60: 98-108.
    • (2010) Zh Vyssh Nerv Deiat im i P Pavlova , vol.60 , pp. 98-108
    • Sarkisova, K.1    Folomkina, A.A.2
  • 79
    • 79956004450 scopus 로고    scopus 로고
    • The WAG/Rij strain: A genetic animal model of absence epilepsy with comorbidity of depression [corrected]
    • Sarkisova K, van Luijtelaar G, (2011). The WAG/Rij strain: a genetic animal model of absence epilepsy with comorbidity of depression [corrected]. Prog Neuropsychopharmacol Biol Psychiatry 35: 854-876.
    • (2011) Prog Neuropsychopharmacol Biol Psychiatry , vol.35 , pp. 854-876
    • Sarkisova, K.1    Van Luijtelaar, G.2
  • 81
    • 0041886973 scopus 로고    scopus 로고
    • Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy
    • Sarkisova KY, Midzianovskaia IS, Kulikov MA, (2003). Depressive-like behavioral alterations and c-fos expression in the dopaminergic brain regions in WAG/Rij rats with genetic absence epilepsy. Behav Brain Res 144: 211-226.
    • (2003) Behav Brain Res , vol.144 , pp. 211-226
    • Sarkisova, K.Y.1    Midzianovskaia, I.S.2    Kulikov, M.A.3
  • 82
    • 38349168729 scopus 로고    scopus 로고
    • Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy
    • Sarkisova KY, Kulikov MA, Midzyanovskaya IS, Folomkina AA, (2008). Dopamine-dependent nature of depression-like behavior in WAG/Rij rats with genetic absence epilepsy. Neurosci Behav Physiol 38: 119-128.
    • (2008) Neurosci Behav Physiol , vol.38 , pp. 119-128
    • Sarkisova, K.Y.1    Kulikov, M.A.2    Midzyanovskaya, I.S.3    Folomkina, A.A.4
  • 83
    • 76249112247 scopus 로고    scopus 로고
    • Spike-wave discharges are necessary for the expression of behavioral depression-like symptoms
    • Sarkisova KY, Kuznetsova GD, Kulikov MA, van Luijtelaar G, (2010). Spike-wave discharges are necessary for the expression of behavioral depression-like symptoms. Epilepsia 51: 146-160.
    • (2010) Epilepsia , vol.51 , pp. 146-160
    • Sarkisova, K.Y.1    Kuznetsova, G.D.2    Kulikov, M.A.3    Van Luijtelaar, G.4
  • 84
    • 1942473841 scopus 로고    scopus 로고
    • Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy
    • Savic I, Lindstrom P, Gulyas B, Halldin C, Andree B, Farde L, (2004). Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy. Neurology 62: 1343-1351.
    • (2004) Neurology , vol.62 , pp. 1343-1351
    • Savic, I.1    Lindstrom, P.2    Gulyas, B.3    Halldin, C.4    Andree, B.5    Farde, L.6
  • 86
    • 0029670753 scopus 로고    scopus 로고
    • Abnormalities in 5-HT1A and 5-HT1B receptor binding in severe-seizure genetically epilepsy-prone rats (GEPR-9s)
    • Statnick MA, Dailey JW, Jobe PC, Browning RA, (1996a). Abnormalities in 5-HT1A and 5-HT1B receptor binding in severe-seizure genetically epilepsy-prone rats (GEPR-9s). Neuropharmacology 35: 111-118.
    • (1996) Neuropharmacology , vol.35 , pp. 111-118
    • Statnick, M.A.1    Dailey, J.W.2    Jobe, P.C.3    Browning, R.A.4
  • 87
    • 0030592506 scopus 로고    scopus 로고
    • Effect of 5,7-dihydroxytryptamine on audiogenic seizures in genetically epilepsy-prone rats
    • Statnick MA, Maring-Smith ML, Clough RW, Wang C, Dailey JW, Jobe PC, et al. (1996b). Effect of 5,7-dihydroxytryptamine on audiogenic seizures in genetically epilepsy-prone rats. Life Sci 59: 1763-1771.
    • (1996) Life Sci , vol.59 , pp. 1763-1771
    • Statnick, M.A.1    Maring-Smith, M.L.2    Clough, R.W.3    Wang, C.4    Dailey, J.W.5    Jobe, P.C.6
  • 88
    • 77953546161 scopus 로고    scopus 로고
    • Epilepsy and serotonin (5-HT): Variations of 5-HT-related genes in temporal lobe epilepsy
    • Stefulj J, Bordukalo-Niksic T, Hecimovic H, Demarin V, Jernej B, (2010). Epilepsy and serotonin (5-HT): variations of 5-HT-related genes in temporal lobe epilepsy. Neurosci Lett 478: 29-31.
    • (2010) Neurosci Lett , vol.478 , pp. 29-31
    • Stefulj, J.1    Bordukalo-Niksic, T.2    Hecimovic, H.3    Demarin, V.4    Jernej, B.5
  • 90
  • 91
    • 77955164450 scopus 로고    scopus 로고
    • Clinical outcome and tolerability of duloxetine in the treatment of major depressive disorder: A 12-week study with plasma levels
    • Volonteri LS, Colasanti A, Cerveri G, Fiorentini A, De Gaspari IF, Mauri MC, et al. (2010). Clinical outcome and tolerability of duloxetine in the treatment of major depressive disorder: a 12-week study with plasma levels. J Psychopharmacol 24: 1193-1199.
    • (2010) J Psychopharmacol , vol.24 , pp. 1193-1199
    • Volonteri, L.S.1    Colasanti, A.2    Cerveri, G.3    Fiorentini, A.4    De Gaspari, I.F.5    Mauri, M.C.6
  • 92
    • 0023949536 scopus 로고
    • Effects of drugs affecting dopaminergic neurotransmission in rats with spontaneous petit mal-like seizures
    • Warter JM, Vergnes M, Depaulis A, Tranchant C, Rumbach L, Micheletti G, et al. (1988). Effects of drugs affecting dopaminergic neurotransmission in rats with spontaneous petit mal-like seizures. Neuropharmacology 27: 269-274.
    • (1988) Neuropharmacology , vol.27 , pp. 269-274
    • Warter, J.M.1    Vergnes, M.2    Depaulis, A.3    Tranchant, C.4    Rumbach, L.5    Micheletti, G.6
  • 93
    • 0036019857 scopus 로고    scopus 로고
    • The role of catecholamines in seizure susceptibility: New results using genetically engineered mice
    • Weinshenker D, Szot P, (2002). The role of catecholamines in seizure susceptibility: new results using genetically engineered mice. Pharmacol Ther 94: 213-233.
    • (2002) Pharmacol Ther , vol.94 , pp. 213-233
    • Weinshenker, D.1    Szot, P.2
  • 94
    • 84899155654 scopus 로고    scopus 로고
    • Searching for the ideal antiepileptogenic agent in experimental models: Single treatment versus combinatorial treatment strategies
    • White HS, Loscher W, (2014). Searching for the ideal antiepileptogenic agent in experimental models: single treatment versus combinatorial treatment strategies. Neurother 11: 373-384.
    • (2014) Neurother , vol.11 , pp. 373-384
    • White, H.S.1    Loscher, W.2
  • 95
    • 0031684641 scopus 로고    scopus 로고
    • Duloxetine (LY 248686): An inhibitor of serotonin and noradrenaline uptake and an antidepressant drug candidate
    • Wong DT, (1998). Duloxetine (LY 248686): an inhibitor of serotonin and noradrenaline uptake and an antidepressant drug candidate. Expert Opin Investig Drugs 7: 1691-1699.
    • (1998) Expert Opin Investig Drugs , vol.7 , pp. 1691-1699
    • Wong, D.T.1
  • 96
  • 97
    • 0027957693 scopus 로고
    • Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats
    • Yan QS, Jobe PC, Dailey JW, (1994b). Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats. Eur J Pharmacol 252: 105-112.
    • (1994) Eur J Pharmacol , vol.252 , pp. 105-112
    • Yan, Q.S.1    Jobe, P.C.2    Dailey, J.W.3
  • 98
    • 0032509761 scopus 로고    scopus 로고
    • Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): A microinjection study
    • Yan QS, Dailey JW, Steenbergen JL, Jobe PC, (1998). Anticonvulsant effect of enhancement of noradrenergic transmission in the superior colliculus in genetically epilepsy-prone rats (GEPRs): a microinjection study. Brain Res 780: 199-209.
    • (1998) Brain Res , vol.780 , pp. 199-209
    • Yan, Q.S.1    Dailey, J.W.2    Steenbergen, J.L.3    Jobe, P.C.4


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