Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy

Neuroscience Letters

Volumn 359, Issue 1-2, 2004, Pages 45-48

  Graf, Marton ^a   Jakus, Rita ^a   Kantor, Sandor ^a   Levay, Gyorgy ^b   Bagdy, Gyorgy ^a  

^a NATIONAL INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Hungary)

^b EGIS PHARMACEUTICALS LTD   (Hungary)

Author keywords

5 HT1A receptor; 5 HT7 receptor; Absence epilepsy; Animal model; Spike wave discharges; WAG Rij rat

Indexed keywords

N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1 ANTAGONIST; SEROTONIN 7 ANTAGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; SEROTONIN 1A RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG SELECTIVITY; EPILEPSY; EXPERIMENTAL MODEL; EXPERIMENTAL TEST; INTERMETHOD COMPARISON; LATENT PERIOD; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE; STATISTICAL SIGNIFICANCE; ABSENCE; ANIMAL; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; WISTAR RAT;

ANIMALS; DISEASE MODELS, ANIMAL; EPILEPSY, ABSENCE; MALE; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 1842608901     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.01.072     Document Type: Article

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