Ethosuximide reduces epileptogenesis and behavioral comorbidity in the GAERS model of genetic generalized epilepsy

Epilepsia

Volumn 54, Issue 4, 2013, Pages 635-643

  Dezsi, Gabi ^a   Ozturk, Ezgi ^a   Stanic, Davor ^b   Powell, Kim L ^a   Blumenfeld, Hal ^c   O'Brien, Terence J ^a   Jones, Nigel C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Anxiety; DNA methylation; Epileptogenesis; Ethosuximide; Genetic absence epilepsy rats from Strasbourg; Seizures

Indexed keywords

DNA METHYLTRANSFERASE; DRINKING WATER; ETHOSUXIMIDE; MESSENGER RNA; TAP WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; AUTOPSY; BRAIN REGION; COMORBIDITY; CONTROLLED STUDY; DISEASE SEVERITY; ELECTROENCEPHALOGRAPHY; EPILEPTOGENESIS; GENE EXPRESSION; GENERALIZED ANXIETY DISORDER; GENERALIZED EPILEPSY; GENETIC GENERALIZED ANXIETY; GENETIC GENERALIZED EPILEPSY; NONHUMAN; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SOMATOSENSORY CORTEX; STUDENT T TEST;

AGING; ANIMALS; ANTICONVULSANTS; ANXIETY; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRODES, IMPLANTED; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; EPILEPSY, GENERALIZED; ETHOSUXIMIDE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; POLYMERASE CHAIN REACTION; RATS; SEIZURES;

EID: 84875859244     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.12118     Document Type: Article

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