Thermosensitive progesterone hydrogel: A safe and effective new formulation for vaginal application

Pharmaceutical Research

Volumn 32, Issue 7, 2015, Pages 2266-2279

  Almomen, Aliyah ^a,b   Cho, Sungpil ^a   Yang, Chieh Hsiang ^a,c   Li, Zhengzheng ^e   Jarboe, Elke A ^a   Peterson, C Matthew ^a   Huh, Kang Moo ^d   Janát Amsbury, Margit M ^a,b,c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH   (United States)

^c Department of Electrical and Computer Engineering   (United States)

^d Chungnam National University   (South Korea)

^e TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

glycol chitin; mucoadhesive; progesterone; thermosensitive; vaginal gel

Indexed keywords

CHITIN; GLYCOL; PROGESTERONE; DRUG CARRIER; GLYCOLCHITIN; HYDROGEL; PROGESTERONE RECEPTOR; TISSUE ADHESIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; CLONOGENIC ASSAY; CONTROLLED STUDY; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; DRUG SAFETY; DRUG SOLUBILITY; ENDOMETRIUM HYPERPLASIA; EPITHELIUM CELL; FEMALE; FLOW MEASUREMENT; GELATION; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; LACTOBACILLUS; MOUSE; MTT ASSAY; NONHUMAN; PH; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY; VAGINA; VAGINA DISCHARGE; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENDOMETRIAL HYPERPLASIA; FLOW KINETICS; GENETICS; HEK293 CELL LINE; INTRAVAGINAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; MICROBIOLOGY; PHASE TRANSITION; TEMPERATURE; VISCOSITY;

ADMINISTRATION, INTRAVAGINAL; ANIMALS; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; CHITIN; DRUG CARRIERS; DRUG LIBERATION; ENDOMETRIAL HYPERPLASIA; EPITHELIAL CELLS; FEMALE; HEK293 CELLS; HUMANS; HYDROGELS; LACTOBACILLUS; MICE; PHASE TRANSITION; PROGESTERONE; RECEPTORS, PROGESTERONE; RHEOLOGY; TEMPERATURE; TISSUE ADHESIVES; VAGINA; VISCOSITY;

EID: 84930182924     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1616-8     Document Type: Article

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