Matched-samples comparison of intramuscular versus vaginal progesterone for luteal phase support after in vitro fertilization and embryo transfer

Fertility and Sterility

Volumn 91, Issue 6, 2009, Pages 2445-2450

  Khan, Naveed ^a   Richter, Kevin S ^a   Newsome, Tasha L ^a   Blake, Emily J ^b   Yankov, Vladimir I ^b  

^a Shady Grove Fertility Reproductive Science Center   (United States)

^b Ferring Pharmaceuticals Inc USA   (United States)

Author keywords

in vitro fertilization; intramuscular; live birth rate; luteal phase support; pregnancy rate; progesterone; Vaginal

Indexed keywords

ENDOMETRIN; ESTRADIOL; GONADORELIN; GONADORELIN AGONIST; HUMAN MENOPAUSAL GONADOTROPIN; ORAL CONTRACEPTIVE AGENT; PROGESTERONE; RECOMBINANT FOLLITROPIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BIRTH RATE; CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE REDUCTION; DRUG EFFICACY; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; LIVE BIRTH; LUTEAL PHASE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PHASE 3 CLINICAL TRIAL; PREGNANCY OUTCOME; PREGNANCY RATE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RETROSPECTIVE STUDY; SAMPLING; SPONTANEOUS ABORTION;

ABORTION, SPONTANEOUS; BIRTH RATE; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HUMANS; INFANT, NEWBORN; INJECTIONS; INJECTIONS, INTRAMUSCULAR; PREGNANCY; PREGNANCY OUTCOME; PROGESTERONE; VAGINA;

EID: 67349144640     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2008.03.072     Document Type: Article

References (24)

1. Daya S. Ovulation induction for corpus luteum deficiency. Semin Reprod Endocrinol 8 (1990) 156-165
2. DiLuigi A.J., and Nulsen J.C. Effects of gonadotropin-releasing hormone agonists and antagonists on luteal function. Curr Opin Obstet Gynecol 19 (2007) 258-265
3. Smitz J., Devroey P., Camus M., Deschacht J., Khan I., Staessen C., et al. The luteal phase and early pregnancy after combined GnRH-agonist/HMG treatment for superovulation in IVF or GIFT. Hum Reprod 3 (1988) 585-590
4. Vande Wiele R.L., Bogumil J., Dyrenfurth I., Ferin M., Jewelewicz R., Warren M., et al. Mechanisms regulating the menstrual cycle in women. Recent Prog Horm Res 26 (1970) 63-103
5. Garcia J., Jones G.S., Acosta A.A., and Wright Jr. G.L. Corpus luteum function after follicle aspiration for oocyte retrieval. Fertil Steril 36 (1981) 565-572
6. Frydman R., Testart J., Giacomini P., Imbert M.C., Martin E., and Nahoul K. Hormonal and histological study of the luteal phase in women following aspiration of the preovulatory follicle. Fertil Steril 38 (1982) 312-317
7. Daya S., and Gunby J. Luteal phase support in assisted reproduction cycles. Cochrane Database Syst Rev (2004) CD004830
8. Nosarka S., Kruger T., Siebert I., and Grove D. Luteal phase support in in vitro fertilization: meta-analysis of randomized trials. Gynecol Obstet Invest 60 (2005) 67-74
9. Farhi J., Weissman A., Steinfeld Z., Shorer M., Nahum H., and Levran D. Estradiol supplementation during the luteal phase may improve the pregnancy rate in patients undergoing in vitro fertilization-embryo transfer cycles. Fertil Steril 73 (2000) 761-766
10. Gorkemli H., Ak D., Akyurek C., Aktan M., and Duman S. Comparison of pregnancy outcomes of progesterone or progesterone + estradiol for luteal phase support in ICSI-ET cycles. Gynecol Obstet Invest 58 (2004) 140-144
11. McAuley J.W., Kroboth F.J., and Kroboth P.D. Oral administration of micronized progesterone: a review and more experience. Pharmacotherapy 16 (1996) 453-457
12. Licciardi F.L., Kwiatkowski A., Noyes N.L., Berkeley A.S., Krey L.L., and Grifo J.A. Oral versus intramuscular progesterone for in vitro fertilization: a prospective randomized study. Fertil Steril 71 (1999) 614-618
13. Miles R.A., Paulson R.J., Lobo R.A., Press M.F., Dahmoush L., and Sauer M.V. Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study. Fertil Steril 62 (1994) 485-490
14. de Ziegler D. Hormonal control of endometrial receptivity. Hum Reprod 10 (1995) 4-7
15. Levine H., and Watson N. Comparison of the pharmacokinetics of crinone 8% administered vaginally versus Prometrium administered orally in postmenopausal women. Fertil Steril 73 (2000) 516-521
16. Pouly J.L., Bassil S., Frydman R., Hedon B., Nicollet B., Prada Y., et al. Luteal support after in-vitro fertilization: Crinone 8%, a sustained release vaginal progesterone gel, versus Utrogestan, an oral micronized progesterone. Hum Reprod 11 (1996) 2085-2089
17. Ng E.H., Chan C.C., Tang O.S., and Ho P.C. A randomized comparison of side effects and patient convenience between Cyclogest suppositories and Endometrin tablets used for luteal phase support in IVF treatment. Eur J Obstet Gynecol Reprod Biol 131 (2007) 182-188
18. Preston R., Norris P., Blake E., and Yankov V. Single day and multiple day pharmacokinetics of a novel vaginal micronized progesterone tablet (Endometrin) compared to Crinone vaginal gel in healthy female subjects. Reprod Sci 14 (2007) 198A
19. Doody K., Shamma N., Paulson R., Bayer S., Blake E., and Yankov V. Endometrin for luteal phase support in a randomized, controlled, open-label, prospective IVF clinical trial using a combination of Menopur and Bravelle. Fertil Steril 87 (2007) s24
20. Gibbons W.E., Toner J.P., Hamacher P., and Kolm P. Experience with a novel vaginal progesterone preparation in a donor oocyte program. Fertil Steril 69 (1998) 96-101
21. Chantilis S.J., Zeitoun K.M., Patel S.I., Johns D.A., Madziar V.A., and McIntire D.D. Use of Crinone vaginal progesterone gel for luteal support in in vitro fertilization cycles. Fertil Steril 72 (1999) 823-829
22. Schoolcraft W.B., Hesla J.S., and Gee M.J. Experience with progesterone gel for luteal support in a highly successful IVF programme. Hum Reprod 15 (2000) 1284-1288
23. Yanushpolsky E., Hurwitz S., Greenberg L., Racowsky C., and Hornstein M.D. Comparison of Crinone 8% intravaginal gel and intramuscular progesterone supplementation for in vitro fertilization/embryo transfer in women under age 40: interim analysis of a prospective randomized trial. Fertil Steril 89 (2007) 485-487
24. Propst A.M., Hill J.A., Ginsburg E.S., Hurwitz S., Politch J., and Yanushpolsky E.H. A randomized study comparing Crinone 8% and intramuscular progesterone supplementation in in vitro fertilization-embryo transfer cycles. Fertil Steril 76 (2001) 1144-1149