An investigation of nifedipine miscibility in solid dispersions using raman spectroscopy

Pharmaceutical Research

Volumn 32, Issue 7, 2015, Pages 2458-2473

  Keratichewanun, Sujinda ^a   Yoshihashi, Yasuo ^b   Sutanthavibul, Narueporn ^a   Terada, Katsuhide ^b   Chatchawalsaisin, Jittima ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b TOHO UNIVERSITY   (Japan)

Author keywords

drug polymer interaction; Gaussian function; molecular dispersion; nifedipine; Raman spectroscopy

Indexed keywords

COPOLYMER; MACROGOL; NIFEDIPINE; POLYVINYL ACETATE; POLYVINYL CAPROLACTAM; POLYVINYL DERIVATIVE; UNCLASSIFIED DRUG; CALCIUM CHANNEL BLOCKING AGENT; EXCIPIENT; MACROGOL DERIVATIVE; POLYVINYL CAPROLACTAM-POLYVINYL ACETATE-POLYETHYLENE GLYCOL GRAFT COPOLYMER;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL INTERACTION; CONTROLLED STUDY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG STABILITY; EVAPORATION; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILICITY; INFRARED SPECTROSCOPY; MELTING POINT; MISCIBILITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAMAN SPECTROMETRY; SOLID STATE; X RAY POWDER DIFFRACTION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG FORMULATION; DRUG INTERACTION; PHASE TRANSITION; SOLUBILITY;

CALCIUM CHANNEL BLOCKERS; CRYSTALLIZATION; DRUG COMPOUNDING; DRUG INTERACTIONS; DRUG STABILITY; EXCIPIENTS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NIFEDIPINE; PHASE TRANSITION; POLYETHYLENE GLYCOLS; POLYVINYLS; SOLUBILITY; SPECTRUM ANALYSIS, RAMAN;

EID: 84930181503     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-015-1638-x     Document Type: Article

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