Drug-polymer intermolecular interactions in hot-melt extruded solid dispersions

International Journal of Pharmaceutics

Volumn 443, Issue 1-2, 2013, Pages 199-208

  Maniruzzaman, Mohammed ^a   Morgan, David J ^b   Mendham, Andrew P ^a   Pang, Jiayun ^a   Snowden, Martin J ^a   Douroumis, Dennis ^a  

^a UNIVERSITY OF GREENWICH   (United Kingdom)

^b CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Hot melt extrusion; Intermolecular interactions; X ray photoelectron spectroscopy

Indexed keywords

ACRYLIC ACID ETHYL ESTER; COPOLYMER; DIPHENHYDRAMINE; DRUG CARRIER; METHACRYLIC ACID; METHACRYLIC ACID METHYL ESTER; PROPRANOLOL;

ARTICLE; DISPERSION; DRUG POLYMER INTERACTION; HYDROGEN BOND; MISCIBILITY; MOLECULAR INTERACTION; MOLECULAR MODEL; PH; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; SURFACE PROPERTY; X RAY PHOTOELECTRON SPECTROSCOPY;

ACRYLIC RESINS; ANIONS; CALORIMETRY, DIFFERENTIAL SCANNING; CATIONS; DIPHENHYDRAMINE; DRUG CARRIERS; DRUG COMPOUNDING; HOT TEMPERATURE; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON, SCANNING; MODELS, MOLECULAR; PHOTOELECTRON SPECTROSCOPY; POLYMETHACRYLIC ACIDS; PROPRANOLOL; SOLUBILITY; SURFACE PROPERTIES; TRANSITION TEMPERATURE; X-RAY DIFFRACTION;

EID: 84873998436     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.11.048     Document Type: Article

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