Polymorphism and devitrification of nifedipine under controlled humidity: A combined FT-Raman, IR and Raman microscopic investigation

Journal of Raman Spectroscopy

Volumn 35, Issue 5, 2004, Pages 353-359

  Chan, K L A ^a   Fleming, O S ^a   Kazarian, S G ^a   Vassou, D ^b   Chryssikos, G D ^b   Gionis, V ^b  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b INSTITUTE OF BIOLOGY   (Greece)

Author keywords

Crystallization; Drugs; FT IR; Infrared microscopy; Moisture; Nifedipine; Polymorphism; Raman microscopy

Indexed keywords

CONTROLLED DRUG DELIVERY; GLASS; HUMIDITY CONTROL; POLYMORPHISM;

%MOISTURE; CONTROLLED HUMIDITIES; CRYSTALLINE PHASIS; DRUG; FT-RAMAN; INFRARED MICROSCOPY; METASTABLES; NIFEDIPINE; RAMAN MICROSCOPY; STRUCTURAL CHARACTERISTICS;

PYRIDINE;

1,4 DIHYDROPYRIDINE DERIVATIVE; ANTIHYPERTENSIVE AGENT; GLASS; NIFEDIPINE;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DRUG CONFORMATION; FOURIER TRANSFORM RAMAN SPECTROMETRY; FOURIER TRANSFORMATION; FREEZING; HUMIDITY; INFRARED SPECTROSCOPY; MELTING POINT; MICROSCOPY; MOISTURE; MOLECULAR STABILITY; PHASE TRANSITION; RAMAN MICROSCOPY; RAMAN SPECTROMETRY; TEMPERATURE; THERMODYNAMICS; VITRIFICATION;

EID: 2442648607     PISSN: 03770486     EISSN: None     Source Type: Journal    
DOI: 10.1002/jrs.1139     Document Type: Article

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