Preparation of carbamazepine-Soluplus® solid dispersions by hot-melt extrusion, and prediction of drug-polymer miscibility by thermodynamic model fitting

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 84, Issue 1, 2013, Pages 228-237

  Djuris, Jelena ^a   Nikolakakis, Ioannis ^b   Ibric, Svetlana ^a   Djuric, Zorica ^a   Kachrimanis, Kyriakos ^b  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Carbamazepine; Flory Huggins; Hansen solubility parameter; Hot melt extrusion; Solid dispersion; Soluplus

Indexed keywords

CARBAMAZEPINE; PLASTICIZER; POLYETHYLENEGLYCOL POLYVINYL CAPROLACTAM POLYVINYL ACETATE GRAFTED COPOLYMER; POLYMER; UNCLASSIFIED DRUG;

ARTICLE; COOLING; DISPERSION; DRUG SOLUBILITY; ENVIRONMENTAL TEMPERATURE; INFRARED SPECTROSCOPY; MISCIBILITY; TEMPERATURE; THERMODYNAMICS; THERMOGRAVIMETRY;

CARBAMAZEPINE; CHEMISTRY, PHARMACEUTICAL; FORECASTING; HOT TEMPERATURE; POLYETHYLENE GLYCOLS; POLYMERS; POLYVINYLS; THERMODYNAMICS;

EID: 84876933684     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.12.018     Document Type: Article

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