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Volumn 9, Issue 8, 2014, Pages

A comparative analysis of constitutive promoters located in adeno-associated viral vectors

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; ELONGATION FACTOR 1ALPHA; PARVOVIRUS VECTOR; THYMIDINE KINASE; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; P16 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL GLYCAN-CLASS A PROTEIN; TUMOR PROTEIN; VIRUS DNA;

EID: 84930166033     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106472     Document Type: Article
Times cited : (30)

References (64)
  • 1
    • 0022977978 scopus 로고
    • Powerful and versatile enhancer-promoter unit for mammalian expression vectors
    • DOI 10.1016/0378-1119(86)90137-X
    • Foecking MK, Hofstetter H (1986) Powerful and versatile enhancer-promoter unit for mammalian expression vectors. Gene 45: 101-105. (Pubitemid 17169237)
    • (1986) Gene , vol.45 , Issue.1 , pp. 101-105
    • Foecking, M.K.1    Hofstetter, H.2
  • 2
    • 27144516425 scopus 로고    scopus 로고
    • Optimization of adenovirus serotype 35 vectors for efficient transduction in human hematopoietic progenitors: Comparison of promoter activities
    • DOI 10.1038/sj.gt.3302562, PII 3302562
    • Sakurai F, Kawabata K, Yamaguchi T, Hayakawa T, Mizuguchi H (2005) Optimization of adenovirus serotype 35 vectors for efficient transduction in human hematopoietic progenitors: comparison of promoter activities. Gene Ther 12: 1424-1433. (Pubitemid 41486131)
    • (2005) Gene Therapy , vol.12 , Issue.19 , pp. 1424-1433
    • Sakurai, F.1    Kawabata, K.2    Yamaguchi, T.3    Hayakawa, T.4    Mizuguchi, H.5
  • 3
    • 33645532672 scopus 로고    scopus 로고
    • Promoter dependence of transgene expression by lentivirus-transduced human blood-derived endothelial progenitor cells
    • Liu JW, Pernod G, Dunoyer-Geindre S, Fish RJ, Yang H, et al. (2006) Promoter dependence of transgene expression by lentivirus-transduced human blood-derived endothelial progenitor cells. Stem Cells 24: 199-208.
    • (2006) Stem Cells , vol.24 , pp. 199-208
    • Liu, J.W.1    Pernod, G.2    Dunoyer-Geindre, S.3    Fish, R.J.4    Yang, H.5
  • 4
    • 84865650793 scopus 로고    scopus 로고
    • Assessment of the long-term transcriptional activity of a 550-bp-long human beta-actin promoter region
    • Damdindorj L, Karnan S, Ota A, Takahashi M, Konishi Y, et al. (2012) Assessment of the long-term transcriptional activity of a 550-bp-long human beta-actin promoter region. Plasmid 68: 195-200.
    • (2012) Plasmid , vol.68 , pp. 195-200
    • Damdindorj, L.1    Karnan, S.2    Ota, A.3    Takahashi, M.4    Konishi, Y.5
  • 5
    • 0033571986 scopus 로고    scopus 로고
    • Use of the human EF-1alpha promotor for expression can significantly increase success in establishing stable cell lines with consistent expression: A study using the tetracycline-inducible system in human cancer cells
    • Gopalkrishnan RV, Christiansen KA, Goldstein NI, DePinho RA, Fisher PB (1999) Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells. Nucleic Acids Res 27: 4775-4782. (Pubitemid 30006668)
    • (1999) Nucleic Acids Research , vol.27 , Issue.24 , pp. 4775-4782
    • Gopalkrishnan, R.V.1    Christiansen, K.A.2    Goldstein, N.I.3    DePinho, R.A.4    Fisher, P.B.5
  • 6
    • 0035166381 scopus 로고    scopus 로고
    • Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter
    • DOI 10.1038/sj.gt.3301561
    • Gill DR, Smyth SE, Goddard CA, Pringle IA, Higgins CF, et al. (2001) Increased persistence of lung gene expression using plasmids containing the ubiquitin C or elongation factor 1alpha promoter. Gene Ther 8: 1539-1546. (Pubitemid 33061892)
    • (2001) Gene Therapy , vol.8 , Issue.20 , pp. 1539-1546
    • Gill, D.R.1    Smyth, S.E.2    Goddard, C.A.3    Pringle, I.A.4    Higgins, C.F.5    Colledge, W.H.6    Hyde, S.C.7
  • 7
    • 0142227898 scopus 로고    scopus 로고
    • Stable Expression of hrGFP by Mouse Embryonic Stem Cells: Promoter Activity in the Undifferentiated State and During Dopaminergic Neural Differentiation
    • Zeng X, Chen J, Sanchez JF, Coggiano M, Dillon-Carter O, et al. (2003) Stable expression of hrGFP by mouse embryonic stem cells: promoter activity in the undifferentiated state and during dopaminergic neural differentiation. Stem Cells 21: 647-653. (Pubitemid 37329157)
    • (2003) Stem Cells , vol.21 , Issue.6 , pp. 647-653
    • Zeng, X.1    Chen, J.2    Sanchez, J.F.3    Coggiano, M.4    Dillon-Carter, O.5    Petersen, J.6    Freed, W.J.7
  • 8
    • 34547117857 scopus 로고    scopus 로고
    • Transient and stable transgene expression in human embryonic stem cells
    • DOI 10.1634/stemcells.2006-0634
    • Liew CG, Draper JS, Walsh J, Moore H, Andrews PW (2007) Transient and stable transgene expression in human embryonic stem cells. Stem Cells 25: 1521-1528. (Pubitemid 47106021)
    • (2007) Stem Cells , vol.25 , Issue.6 , pp. 1521-1528
    • Liew, C.-G.1    Draper, J.S.2    Walsh, J.3    Moore, H.4    Andrews, P.W.5
  • 10
    • 77956551196 scopus 로고    scopus 로고
    • Systematic comparison of constitutive promoters and the doxycycline-inducible promoter
    • Qin JY, Zhang L, Clift KL, Hulur I, Xiang AP, et al. (2010) Systematic comparison of constitutive promoters and the doxycycline-inducible promoter. PLoS One 5: e10611.
    • (2010) PLoS One , vol.5
    • Qin, J.Y.1    Zhang, L.2    Clift, K.L.3    Hulur, I.4    Xiang, A.P.5
  • 11
    • 80051613693 scopus 로고    scopus 로고
    • A comparison of exogenous promoter activity at the ROSA26 locus using a PhiiC31 integrase mediated cassette exchange approach in mouse ES cells
    • Chen CM, Krohn J, Bhattacharya S, Davies B (2011) A comparison of exogenous promoter activity at the ROSA26 locus using a PhiiC31 integrase mediated cassette exchange approach in mouse ES cells. PLoS One 6: e23376.
    • (2011) PLoS One , vol.6
    • Chen, C.M.1    Krohn, J.2    Bhattacharya, S.3    Davies, B.4
  • 13
    • 0026091363 scopus 로고
    • Stable expression of human tissue-type plasminogen activator regulated by beta-actin promoter in three human cell lines: HeLa, WI-38 VA13 and KMS-5
    • Morishita H, Nakamura N, Yamakawa T, Ogino H, Kanamori T, et al. (1991) Stable expression of human tissue-type plasminogen activator regulated by beta-actin promoter in three human cell lines: HeLa, WI-38 VA13 and KMS-5. Biochim Biophys Acta 1090: 216-222.
    • (1991) Biochim Biophys Acta , vol.1090 , pp. 216-222
    • Morishita, H.1    Nakamura, N.2    Yamakawa, T.3    Ogino, H.4    Kanamori, T.5
  • 14
    • 0026112545 scopus 로고
    • Constitutive high-level production of human lymphotoxin by CHO-K1 cells transformed with the human lymphotoxin gene controlled by a human beta-actin promoter
    • Nakagawa K, Yajima K, Yamashita K, Ikenaka Y, Yokota S, et al. (1991) Constitutive high-level production of human lymphotoxin by CHO-K1 cells transformed with the human lymphotoxin gene controlled by a human beta-actin promoter. Agric Biol Chem 55: 501-508.
    • (1991) Agric Biol Chem , vol.55 , pp. 501-508
    • Nakagawa, K.1    Yajima, K.2    Yamashita, K.3    Ikenaka, Y.4    Yokota, S.5
  • 15
    • 0027134830 scopus 로고
    • An efficient expression vector for stable expression in human liver cells
    • Kim DW, Harada T, Saito I, Miyamura T (1993) An efficient expression vector for stable expression in human liver cells. Gene 134: 307-308.
    • (1993) Gene , vol.134 , pp. 307-308
    • Kim, D.W.1    Harada, T.2    Saito, I.3    Miyamura, T.4
  • 16
    • 0033119849 scopus 로고    scopus 로고
    • Persistent expression of foreign genes in cultured hepatocytes: Expression vectors
    • DOI 10.1016/S0378-1119(99)00052-9, PII S0378111999000529
    • Najjar SM, Lewis RE (1999) Persistent expression of foreign genes in cultured hepatocytes: expression vectors. Gene 230: 41-45. (Pubitemid 29193193)
    • (1999) Gene , vol.230 , Issue.1 , pp. 41-45
    • Najjar, S.M.1    Lewis, R.E.2
  • 17
    • 0034535822 scopus 로고    scopus 로고
    • Strong, long-term transgene expression in rat liver using chicken beta-Actin promoter associated with cytomegalovirus immediate-early enhancer (CAG promoter)
    • Kosuga M, Enosawa S, Li XK, Suzuki S, Matsuo N, et al. (2000) Strong, long-term transgene expression in rat liver using chicken beta-actin promoter associated with cytomegalovirus immediate-early enhancer (CAG promoter). Cell Transplant 9: 675-680. (Pubitemid 32002574)
    • (2000) Cell Transplantation , vol.9 , Issue.5 , pp. 675-680
    • Kosuga, M.1    Enosawa, S.2    Li, X.-K.3    Suzuki, S.4    Matsuo, N.5    Yamada, M.6    Roy-Chowdhury, J.7    Koiwai, O.8    Okuyama, T.9
  • 18
    • 54249126862 scopus 로고    scopus 로고
    • Gene therapy using adeno-associated virus vectors
    • Daya S, Berns KI (2008) Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 21: 583-593.
    • (2008) Clin Microbiol Rev , vol.21 , pp. 583-593
    • Daya, S.1    Berns, K.I.2
  • 19
    • 44049094771 scopus 로고    scopus 로고
    • Clinical gene therapy using recombinant adeno-associated virus vectors
    • DOI 10.1038/gt.2008.68, PII GT200868, Special Issue: AAV Vectors for Clinical GeneTherapy
    • Mueller C, Flotte TR (2008) Clinical gene therapy using recombinant adenoassociated virus vectors. Gene Ther 15: 858-863. (Pubitemid 351712619)
    • (2008) Gene Therapy , vol.15 , Issue.11 , pp. 858-863
    • Mueller, C.1    Flotte, T.R.2
  • 20
    • 0037333815 scopus 로고    scopus 로고
    • Genetic fate of recombinant adeno-associated virus vector genomes in muscle
    • DOI 10.1128/JVI.77.6.3495-3504.2003
    • Schnepp BC, Clark KR, Klemanski DL, Pacak CA, Johnson PR (2003) Genetic fate of recombinant adeno-associated virus vector genomes in muscle. J Virol 77: 3495-3504. (Pubitemid 36297269)
    • (2003) Journal of Virology , vol.77 , Issue.6 , pp. 3495-3504
    • Schnepp, B.C.1    Clark, K.R.2    Klemanski, D.L.3    Pacak, C.A.4    Johnson, P.R.5
  • 21
    • 0036871275 scopus 로고    scopus 로고
    • Comparison of the EF-1alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus
    • Teschendorf C, Warrington KH, Jr., Siemann DW, Muzyczka N (2002) Comparison of the EF-1 alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus. Anticancer Res 22: 3325-3330. (Pubitemid 36070109)
    • (2002) Anticancer Research , vol.22 , Issue.6 A , pp. 3325-3330
    • Teschendorf, C.1    Warrington Jr., K.H.2    Siemann, D.W.3    Muzyczka, N.4
  • 22
    • 0031897270 scopus 로고    scopus 로고
    • Human gene targeting by viral vectors
    • DOI 10.1038/ng0498-325
    • Russell DW, Hirata RK (1998) Human gene targeting by viral vectors. Nat Genet 18: 325-330. (Pubitemid 28158159)
    • (1998) Nature Genetics , vol.18 , Issue.4 , pp. 325-330
    • Russell, D.W.1    Hirata, R.K.2
  • 24
    • 84867289692 scopus 로고    scopus 로고
    • Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene
    • Karnan S, Konishi Y, Ota A, Takahashi M, Damdindorj L, et al. (2012) Simple monitoring of gene targeting efficiency in human somatic cell lines using the PIGA gene. PLoS One 7: e47389.
    • (2012) PLoS One , vol.7
    • Karnan, S.1    Konishi, Y.2    Ota, A.3    Takahashi, M.4    Damdindorj, L.5
  • 25
    • 84866354983 scopus 로고    scopus 로고
    • A system for the measurement of gene targeting efficiency in human cell lines using an antibiotic resistance-GFP fusion gene
    • Konishi Y, Karnan S, Takahashi M, Ota A, Damdindorj L, et al. (2012) A system for the measurement of gene targeting efficiency in human cell lines using an antibiotic resistance-GFP fusion gene. Biotechniques 53: 141-152.
    • (2012) Biotechniques , vol.53 , pp. 141-152
    • Konishi, Y.1    Karnan, S.2    Takahashi, M.3    Ota, A.4    Damdindorj, L.5
  • 26
    • 39149117397 scopus 로고    scopus 로고
    • Genetic knockouts and knockins in human somatic cells
    • Rago C, Vogelstein B, Bunz F (2007) Genetic knockouts and knockins in human somatic cells. Nat Protoc 2: 2734-2746.
    • (2007) Nat Protoc , vol.2 , pp. 2734-2746
    • Rago, C.1    Vogelstein, B.2    Bunz, F.3
  • 28
    • 0023890773 scopus 로고
    • Strong transcriptional promoter in the 59 upstream region of the human beta-actin gene
    • Sugiyama H, Niwa H, Makino K, Kakunaga T (1988) Strong transcriptional promoter in the 59 upstream region of the human beta-actin gene. Gene 65: 135-139.
    • (1988) Gene , vol.65 , pp. 135-139
    • Sugiyama, H.1    Niwa, H.2    Makino, K.3    Kakunaga, T.4
  • 29
    • 0030829653 scopus 로고    scopus 로고
    • Efficiency of recombination by Cre transient expression in embryonic stem cells: Comparison of various promoters
    • Araki K, Imaizumi T, Okuyama K, Oike Y, Yamamura K (1997) Efficiency of recombination by Cre transient expression in embryonic stem cells: comparison of various promoters. J Biochem 122: 977-982. (Pubitemid 27510937)
    • (1997) Journal of Biochemistry , vol.122 , Issue.5 , pp. 977-982
    • Araki, K.1    Imaizumi, T.2    Okuyama, K.3    Oike, Y.4    Yamamura, K.-I.5
  • 30
    • 0023691796 scopus 로고
    • A comparison of bovine growth-hormone gene expression in mouse L cells directed by the Moloney murine-leukemia virus long terminal repeat, simian virus-40 early promoter or cytomegalovirus immediate-early promoter
    • DOI 10.1016/0378-1119(88)90103-5
    • Martin-Gallardo A, Montoya-Zavala M, Kelder B, Taylor J, Chen H, et al. (1988) A comparison of bovine growth-hormone gene expression in mouse L cells directed by the Moloney murine-leukemia virus long terminal repeat, simian virus-40 early promoter or cytomegalovirus immediate-early promoter. Gene 70: 51-56. (Pubitemid 18263482)
    • (1988) Gene , vol.70 , Issue.1 , pp. 51-56
    • Martin-Gallardo, A.1    Montoya-Zavala, M.2    Kelder, B.3    Taylor, J.4    Chen, H.5    Leung, F.C.6    Kopchick, J.J.7
  • 31
    • 0026008881 scopus 로고
    • The variability in activity of the universally expressed human cytomegaloyirus immediate early gene 1 enhancer/promoter in transgenic mice
    • Furth PA, Hennighausen L, Baker C, Beatty B, Woychick R (1991) The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Res 19: 6205-6208. (Pubitemid 21913040)
    • (1991) Nucleic Acids Research , vol.19 , Issue.22 , pp. 6205-6208
    • Furth, P.A.1    Hennighausen, L.2    Baker, C.3    Beatty, B.4    Woychick, R.5
  • 32
    • 0019989719 scopus 로고
    • Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter
    • Southern PJ, Berg P (1982) Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J Mol Appl Genet 1: 327-341. (Pubitemid 12056513)
    • (1982) Journal of Molecular and Applied Genetics , vol.1 , Issue.4 , pp. 327-341
    • Southern, P.J.1    Berg, P.2
  • 33
    • 0021229621 scopus 로고
    • Efficient constitutive production of human fibroblast interferon by hamster cells transformed with the IFN-beta1 gene fused to an SV40 early promoter
    • Chernajovsky Y, Mory Y, Chen L, Marks Z, Novick D, et al. (1984) Efficient constitutive production of human fibroblast interferon by hamster cells transformed with the IFN-beta 1 gene fused to an SV40 early promoter. DNA 3: 297-308. (Pubitemid 14015979)
    • (1984) DNA , vol.3 , Issue.4 , pp. 297-308
    • Chernajovsky, Y.1    Mory, Y.2    Chen, L.3
  • 34
    • 0026903297 scopus 로고
    • Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors
    • Li M, Hantzopoulos PA, Banerjee D, Zhao SC, Schweitzer BI, et al. (1992) Comparison of the expression of a mutant dihydrofolate reductase under control of different internal promoters in retroviral vectors. Hum Gene Ther 3: 381-390.
    • (1992) Hum Gene Ther , vol.3 , pp. 381-390
    • Li, M.1    Hantzopoulos, P.A.2    Banerjee, D.3    Zhao, S.C.4    Schweitzer, B.I.5
  • 35
    • 0020328836 scopus 로고
    • Expression of human beta-interferon cDNA under the control of a thymidine kinase promoter from herpes simplex virus
    • DOI 10.1038/297598a0
    • Reyes GR, Gavis ER, Buchan A, Raj NB, Hayward GS, et al. (1982) Expression of human beta-interferon cDNA under the control of a thymidine kinase promoter from herpes simplex virus. Nature 297: 598-601. (Pubitemid 12027630)
    • (1982) Nature , vol.297 , Issue.5867 , pp. 598-601
    • Reyes, G.R.1    Gavis, E.R.2    Buchan, A.3
  • 36
    • 70349747281 scopus 로고    scopus 로고
    • PMA induces expression from the herpes simplex virus thymidine kinase promoter via the activation of JNK and ERK in the presence of adenoviral E1A proteins
    • Shifera AS, Hardin JA (2009) PMA induces expression from the herpes simplex virus thymidine kinase promoter via the activation of JNK and ERK in the presence of adenoviral E1A proteins. Arch Biochem Biophys 490: 145-157.
    • (2009) Arch Biochem Biophys , vol.490 , pp. 145-157
    • Shifera, A.S.1    Hardin, J.A.2
  • 37
    • 2442466567 scopus 로고    scopus 로고
    • p16 gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma
    • Lee AW, Li JH, Shi W, Li A, Ng E, et al. (2003) p16 gene therapy: a potentially efficacious modality for nasopharyngeal carcinoma. Mol Cancer Ther 2: 961-969.
    • (2003) Mol Cancer Ther , vol.2 , pp. 961-969
    • Lee, A.W.1    Li, J.H.2    Shi, W.3    Li, A.4    Ng, E.5
  • 39
    • 0035114253 scopus 로고    scopus 로고
    • Adenovirus-mediated transfer of p53 and p16INK4a results in pancreatic cancer regression in vitro and in vivo
    • DOI 10.1038/sj.gt.3301394
    • Ghaneh P, Greenhalf W, Humphreys M, Wilson D, Zumstein L, et al. (2001) Adenovirus-mediated transfer of p53 and p16(INK4a) results in pancreatic cancer regression in vitro and in vivo. Gene Ther 8: 199-208. (Pubitemid 32186131)
    • (2001) Gene Therapy , vol.8 , Issue.3 , pp. 199-208
    • Ghaneh, P.1    Greenhalf, W.2    Humphreys, M.3    Wilson, D.4    Zumstein, L.5    Lemoine, N.R.6    Neoptolemos, J.P.7
  • 40
    • 0034115639 scopus 로고    scopus 로고
    • Adenoviral vector containing wild-type p16 suppresses prostate cancer growth and prolongs survival by inducing cell senescence
    • Steiner MS, Zhang Y, Farooq F, Lerner J, Wang Y, et al. (2000) Adenoviral vector containing wild-type p16 suppresses prostate cancer growth and prolongs survival by inducing cell senescence. Cancer Gene Ther 7: 360-372. (Pubitemid 30210403)
    • (2000) Cancer Gene Therapy , vol.7 , Issue.3 , pp. 360-372
    • Steiner, M.S.1    Zhang, Y.2    Farooq, F.3    Lerner, J.4    Wang, Y.5    Lu, Y.6
  • 41
    • 66449127105 scopus 로고    scopus 로고
    • Growth inhibition of human cancer cells by 5-aza-2′-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status
    • Xiong J, Epstein RJ (2009) Growth inhibition of human cancer cells by 5-aza-2′-deoxycytidine does not correlate with its effects on INK4a/ARF expression or initial promoter methylation status. Mol Cancer Ther 8: 779-785.
    • (2009) Mol Cancer Ther , vol.8 , pp. 779-785
    • Xiong, J.1    Epstein, R.J.2
  • 42
  • 44
    • 0027310539 scopus 로고
    • Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria
    • DOI 10.1016/0092-8674(93)90250-T
    • Takeda J, Miyata T, Kawagoe K, Iida Y, Endo Y, et al. (1993) Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria. Cell 73: 703-711. (Pubitemid 23159009)
    • (1993) Cell , vol.73 , Issue.4 , pp. 703-711
    • Takeda, J.1    Miyata, T.2    Kawagoe, K.3    Iida, Y.4    Endo, Y.5    Fujita, T.6    Takahashi, M.7    Kitani, T.8    Kinoshita, T.9
  • 45
    • 69249221393 scopus 로고    scopus 로고
    • How I treat paroxysmal nocturnal hemoglobinuria
    • Brodsky RA (2009) How I treat paroxysmal nocturnal hemoglobinuria. Blood 113: 6522-6527.
    • (2009) Blood , vol.113 , pp. 6522-6527
    • Brodsky, R.A.1
  • 47
    • 84861998784 scopus 로고    scopus 로고
    • Intracellular transport of recombinant adeno-associated virus vectors
    • Nonnenmacher M, Weber T (2012) Intracellular transport of recombinant adeno-associated virus vectors. Gene Ther 19: 649-658.
    • (2012) Gene Ther , vol.19 , pp. 649-658
    • Nonnenmacher, M.1    Weber, T.2
  • 48
    • 84859440283 scopus 로고    scopus 로고
    • The AAV vector toolkit: Poised at the clinical crossroads
    • Asokan A, Schaffer DV, Samulski RJ (2012) The AAV vector toolkit: poised at the clinical crossroads. Mol Ther 20: 699-708.
    • (2012) Mol Ther , vol.20 , pp. 699-708
    • Asokan, A.1    Schaffer, D.V.2    Samulski, R.J.3
  • 49
    • 84884691211 scopus 로고    scopus 로고
    • Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain
    • Aschauer DF, Kreuz S, Rumpel S (2013) Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain. PLoS One 8: e76310.
    • (2013) PLoS One , vol.8
    • Aschauer, D.F.1    Kreuz, S.2    Rumpel, S.3
  • 50
    • 44349170706 scopus 로고    scopus 로고
    • Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
    • DOI 10.1038/mt.2008.76, PII MT200876
    • Zincarelli C, Soltys S, Rengo G, Rabinowitz JE (2008) Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol Ther 16: 1073-1080. (Pubitemid 351737072)
    • (2008) Molecular Therapy , vol.16 , Issue.6 , pp. 1073-1080
    • Zincarelli, C.1    Soltys, S.2    Rengo, G.3    Rabinowitz, J.E.4
  • 53
    • 77649230740 scopus 로고    scopus 로고
    • Cdk2 is required for p53-independent G2/M checkpoint control
    • Chung JH, Bunz F (2010) Cdk2 is required for p53-independent G2/M checkpoint control. PLoS Genet 6: e1000863.
    • (2010) PLoS Genet , vol.6
    • Chung, J.H.1    Bunz, F.2
  • 54
    • 77955288855 scopus 로고    scopus 로고
    • Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus
    • Di Nicolantonio F, Arena S, Tabernero J, Grosso S, Molinari F, et al. (2010) Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus. J Clin Invest 120: 2858-2866.
    • (2010) J Clin Invest , vol.120 , pp. 2858-2866
    • Di Nicolantonio, F.1    Arena, S.2    Tabernero, J.3    Grosso, S.4    Molinari, F.5
  • 55
    • 77649225150 scopus 로고    scopus 로고
    • Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells
    • Fattah F, Lee EH, Weisensel N, Wang Y, Lichter N, et al. (2010) Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells. PLoS Genet 6: e1000855.
    • (2010) PLoS Genet , vol.6
    • Fattah, F.1    Lee, E.H.2    Weisensel, N.3    Wang, Y.4    Lichter, N.5
  • 57
    • 48549084778 scopus 로고    scopus 로고
    • A syngeneic variance library for functional annotation of human variation: Application to BRCA2
    • Hucl T, Rago C, Gallmeier E, Brody JR, Gorospe M, et al. (2008) A syngeneic variance library for functional annotation of human variation: application to BRCA2. Cancer Res 68: 5023-5030.
    • (2008) Cancer Res , vol.68 , pp. 5023-5030
    • Hucl, T.1    Rago, C.2    Gallmeier, E.3    Brody, J.R.4    Gorospe, M.5
  • 58
    • 80055077133 scopus 로고    scopus 로고
    • Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells
    • Konishi H, Mohseni M, Tamaki A, Garay JP, Croessmann S, et al. (2011) Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells. Proc Natl Acad Sci U S A 108: 17773-17778.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 17773-17778
    • Konishi, H.1    Mohseni, M.2    Tamaki, A.3    Garay, J.P.4    Croessmann, S.5
  • 59
    • 80051874823 scopus 로고    scopus 로고
    • Mutational inactivation of STAG2 causes aneuploidy in human cancer
    • Solomon DA, Kim T, Diaz-Martinez LA, Fair J, Elkahloun AG, et al. (2011) Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science 333: 1039-1043.
    • (2011) Science , vol.333 , pp. 1039-1043
    • Solomon, D.A.1    Kim, T.2    Diaz-Martinez, L.A.3    Fair, J.4    Elkahloun, A.G.5
  • 60
    • 70350539589 scopus 로고    scopus 로고
    • Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells
    • Vitolo MI, Weiss MB, Szmacinski M, Tahir K, Waldman T, et al. (2009) Deletion of PTEN promotes tumorigenic signaling, resistance to anoikis, and altered response to chemotherapeutic agents in human mammary epithelial cells. Cancer Res 69: 8275-8283.
    • (2009) Cancer Res , vol.69 , pp. 8275-8283
    • Vitolo, M.I.1    Weiss, M.B.2    Szmacinski, M.3    Tahir, K.4    Waldman, T.5
  • 61
    • 70349331678 scopus 로고    scopus 로고
    • Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells
    • Yun J, Rago C, Cheong I, Pagliarini R, Angenendt P, et al. (2009) Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells. Science 325: 1555-1559.
    • (2009) Science , vol.325 , pp. 1555-1559
    • Yun, J.1    Rago, C.2    Cheong, I.3    Pagliarini, R.4    Angenendt, P.5
  • 62
    • 0024118441 scopus 로고
    • Homologous integration in mammalian cells without target gene selection
    • Jasin M, Berg P (1988) Homologous integration in mammalian cells without target gene selection. Genes Dev 2: 1353-1363.
    • (1988) Genes Dev , vol.2 , pp. 1353-1363
    • Jasin, M.1    Berg, P.2
  • 64
    • 0035989649 scopus 로고    scopus 로고
    • Targeted transgene insertion into human chromosomes by adeno-associated virus vectors
    • DOI 10.1038/nbt0702-735
    • Hirata R, Chamberlain J, Dong R, Russell DW (2002) Targeted transgene insertion into human chromosomes by adeno-associated virus vectors. Nat Biotechnol 20: 735-738. (Pubitemid 34734142)
    • (2002) Nature Biotechnology , vol.20 , Issue.7 , pp. 735-738
    • Hirata, R.1    Chamberlain, J.2    Dong, R.3    Russell, D.W.4


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