-
1
-
-
27544470656
-
Mammalian cyclin-dependent kinases
-
Malumbres M, Barbacid M (2005) Mammalian cyclin-dependent kinases. Trends Biochem Sci 30(11): 630-641.
-
(2005)
Trends Biochem Sci
, vol.30
, Issue.11
, pp. 630-641
-
-
Malumbres, M.1
Barbacid, M.2
-
2
-
-
8644219655
-
Living with or without cyclins and cyclin-dependent kinases
-
Sherr CJ, Roberts JM (2004) Living with or without cyclins and cyclin-dependent kinases. Genes Dev 18(22): 2699-2711.
-
(2004)
Genes Dev
, vol.18
, Issue.22
, pp. 2699-2711
-
-
Sherr, C.J.1
Roberts, J.M.2
-
3
-
-
54549101258
-
Cyclin-dependent kinases and cell-cycle transitions: Does one fit all?
-
Hochegger H, Takeda S, Hunt T (2008) Cyclin-dependent kinases and cell-cycle transitions: Does one fit all? Nat Rev Mol Cell Biol 9(11): 910-916.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.11
, pp. 910-916
-
-
Hochegger, H.1
Takeda, S.2
Hunt, T.3
-
4
-
-
60749109846
-
Cell cycle, CDKs and cancer: A changing paradigm
-
Malumbres M, Barbacid M (2009) Cell cycle, CDKs and cancer: A changing paradigm. Nat Rev Cancer 9(3): 153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, Issue.3
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
5
-
-
34447119665
-
Cell-specific responses to loss of cyclin-dependent kinases
-
Berthet C, Kaldis P (2007) Cell-specific responses to loss of cyclin-dependent kinases. Oncogene 26(31): 4469-4477.
-
(2007)
Oncogene
, vol.26
, Issue.31
, pp. 4469-4477
-
-
Berthet, C.1
Kaldis, P.2
-
6
-
-
0041327168
-
Proliferation of cancer cells despite CDK2 inhibition
-
Tetsu O, McCormick F (2003) Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 3(3): 233-245.
-
(2003)
Cancer Cell
, vol.3
, Issue.3
, pp. 233-245
-
-
Tetsu, O.1
McCormick, F.2
-
7
-
-
0142116249
-
Cdk2 knockout mice are viable
-
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P (2003) Cdk2 knockout mice are viable. Curr Biol 13(20): 1775-1785.
-
(2003)
Curr Biol
, vol.13
, Issue.20
, pp. 1775-1785
-
-
Berthet, C.1
Aleem, E.2
Coppola, V.3
Tessarollo, L.4
Kaldis, P.5
-
8
-
-
33646528191
-
Combined loss of Cdk2 and Cdk4 results in embryonic lethality and rb hypophosphorylation
-
Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, et al. (2006) Combined loss of Cdk2 and Cdk4 results in embryonic lethality and rb hypophosphorylation. Dev Cell 10(5): 563-573.
-
(2006)
Dev Cell
, vol.10
, Issue.5
, pp. 563-573
-
-
Berthet, C.1
Klarmann, K.D.2
Hilton, M.B.3
Suh, H.C.4
Keller, J.R.5
-
9
-
-
0041854279
-
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
Ortega S, Prieto I, Odajima J, Martin A, Dubus P, et al. (2003) Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet 35(1): 25-31.
-
(2003)
Nat Genet
, vol.35
, Issue.1
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
Martin, A.4
Dubus, P.5
-
10
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres M, Sotillo R, Santamaria D, Galan J, Cerezo A, et al. (2004) Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 118(4): 493-504.
-
(2004)
Cell
, vol.118
, Issue.4
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
Galan, J.4
Cerezo, A.5
-
11
-
-
34547952048
-
Cdk1 is sufficient to drive the mammalian cell cycle
-
Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, et al. (2007) Cdk1 is sufficient to drive the mammalian cell cycle. Nature 448(7155): 811-815.
-
(2007)
Nature
, vol.448
, Issue.7155
, pp. 811-815
-
-
Santamaria, D.1
Barriere, C.2
Cerqueira, A.3
Hunt, S.4
Tardy, C.5
-
12
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J (2001) The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410(6830): 842-847.
-
(2001)
Nature
, vol.410
, Issue.6830
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
13
-
-
0036510055
-
The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways
-
Falck J, Petrini JH, Williams BR, Lukas J, Bartek J (2002) The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 30(3): 290-294.
-
(2002)
Nat Genet
, vol.30
, Issue.3
, pp. 290-294
-
-
Falck, J.1
Petrini, J.H.2
Williams, B.R.3
Lukas, J.4
Bartek, J.5
-
14
-
-
34547129599
-
Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage
-
Myers JS, Zhao R, Xu X, Ham AJ, Cortez D (2007) Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage. Cancer Res 67(14): 6685-6690.
-
(2007)
Cancer Res
, vol.67
, Issue.14
, pp. 6685-6690
-
-
Myers, J.S.1
Zhao, R.2
Xu, X.3
Ham, A.J.4
Cortez, D.5
-
15
-
-
38749103066
-
p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint
-
Satyanarayana A, Hilton MB, Kaldis P (2008) p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint. Mol Biol Cell 19(1): 65-77.
-
(2008)
Mol Biol Cell
, vol.19
, Issue.1
, pp. 65-77
-
-
Satyanarayana, A.1
Hilton, M.B.2
Kaldis, P.3
-
16
-
-
20444410393
-
Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1)
-
Martin A, Odajima J, Hunt SL, Dubus P, Ortega S, et al. (2005) Cdk2 is dispensable for cell cycle inhibition and tumor suppression mediated by p27(Kip1) and p21(Cip1). Cancer Cell 7(6): 591-598.
-
(2005)
Cancer Cell
, vol.7
, Issue.6
, pp. 591-598
-
-
Martin, A.1
Odajima, J.2
Hunt, S.L.3
Dubus, P.4
Ortega, S.5
-
17
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, et al. (1998) Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282(5393): 1497-1501.
-
(1998)
Science
, vol.282
, Issue.5393
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
-
18
-
-
0028849274
-
p21 is necessary for the p53-mediated G1 arrest in human cancer cells
-
Waldman T, Kinzler KW, Vogelstein B (1995) p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 55(22): 5187-5190.
-
(1995)
Cancer Res
, vol.55
, Issue.22
, pp. 5187-5190
-
-
Waldman, T.1
Kinzler, K.W.2
Vogelstein, B.3
-
19
-
-
34247332735
-
Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation
-
Hurley PJ, Wilsker D, Bunz F (2007) Human cancer cells require ATR for cell cycle progression following exposure to ionizing radiation. Oncogene 26(18): 2535-2542.
-
(2007)
Oncogene
, vol.26
, Issue.18
, pp. 2535-2542
-
-
Hurley, P.J.1
Wilsker, D.2
Bunz, F.3
-
20
-
-
0034717309
-
Rapid destruction of human Cdc25A in response to DNA damage
-
Mailand N, Falck J, Lukas C, Syljuasen RG, Welcker M, et al. (2000) Rapid destruction of human Cdc25A in response to DNA damage. Science 288(5470): 1425-1429.
-
(2000)
Science
, vol.288
, Issue.5470
, pp. 1425-1429
-
-
Mailand, N.1
Falck, J.2
Lukas, C.3
Syljuasen, R.G.4
Welcker, M.5
-
21
-
-
0012966157
-
Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A
-
Sorensen CS, Syljuasen RG, Falck J, Schroeder T, Ronnstrand L, et al. (2003) Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 3(3): 247-258.
-
(2003)
Cancer Cell
, vol.3
, Issue.3
, pp. 247-258
-
-
Sorensen, C.S.1
Syljuasen, R.G.2
Falck, J.3
Schroeder, T.4
Ronnstrand, L.5
-
22
-
-
0033533612
-
14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage
-
Chan TA, Hermeking H, Lengauer C, Kinzler KW, Vogelstein B (1999) 14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage. Nature 401(6753): 616-620.
-
(1999)
Nature
, vol.401
, Issue.6753
, pp. 616-620
-
-
Chan, T.A.1
Hermeking, H.2
Lengauer, C.3
Kinzler, K.W.4
Vogelstein, B.5
-
23
-
-
0033163714
-
Four-dimensional control of the cell cycle
-
Pines J (1999) Four-dimensional control of the cell cycle. Nat Cell Biol 1(3): E73-9.
-
(1999)
Nat Cell Biol
, vol.1
, Issue.3
-
-
Pines, J.1
-
24
-
-
23144451917
-
Cdc2-cyclin E complexes regulate the G1/S phase transition
-
Aleem E, Kiyokawa H, Kaldis P (2005) Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol 7(8): 831-836.
-
(2005)
Nat Cell Biol
, vol.7
, Issue.8
, pp. 831-836
-
-
Aleem, E.1
Kiyokawa, H.2
Kaldis, P.3
-
25
-
-
33646423584
-
Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines
-
L'Italien L, Tanudji M, Russell L, Schebye XM (2006) Unmasking the redundancy between Cdk1 and Cdk2 at G2 phase in human cancer cell lines. Cell Cycle 5(9): 984-993.
-
(2006)
Cell Cycle
, vol.5
, Issue.9
, pp. 984-993
-
-
L'Italien, L.1
Tanudji, M.2
Russell, L.3
Schebye, X.M.4
-
26
-
-
34248184018
-
Specialized roles of the two mitotic cyclins in somatic cells: Cyclin A as an activator of M phase-promoting factor
-
Fung TK, Ma HT, Poon RY (2007) Specialized roles of the two mitotic cyclins in somatic cells: Cyclin A as an activator of M phase-promoting factor. Mol Biol Cell 18(5): 1861-1873.
-
(2007)
Mol Biol Cell
, vol.18
, Issue.5
, pp. 1861-1873
-
-
Fung, T.K.1
Ma, H.T.2
Poon, R.Y.3
-
27
-
-
33845998239
-
Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin B1
-
Gong D, Pomerening JR, Myers JW, Gustavsson C, Jones JT, et al. (2007) Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin B1. Curr Biol 17(1): 85-91.
-
(2007)
Curr Biol
, vol.17
, Issue.1
, pp. 85-91
-
-
Gong, D.1
Pomerening, J.R.2
Myers, J.W.3
Gustavsson, C.4
Jones, J.T.5
-
28
-
-
2442643936
-
Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells
-
Mitra J, Enders GH (2004) Cyclin A/Cdk2 complexes regulate activation of Cdk1 and Cdc25 phosphatases in human cells. Oncogene 23(19): 3361-3367.
-
(2004)
Oncogene
, vol.23
, Issue.19
, pp. 3361-3367
-
-
Mitra, J.1
Enders, G.H.2
-
29
-
-
47549116177
-
Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events
-
De Boer L, Oakes V, Beamish H, Giles N, Stevens F, et al. (2008) Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events. Oncogene 27(31): 4261-4268.
-
(2008)
Oncogene
, vol.27
, Issue.31
, pp. 4261-4268
-
-
De Boer, L.1
Oakes, V.2
Beamish, H.3
Giles, N.4
Stevens, F.5
-
30
-
-
0032728975
-
Human cyclin A is required for mitosis until mid prophase
-
Furuno N, den Elzen N, Pines J (1999) Human cyclin A is required for mitosis until mid prophase. J Cell Biol 147(2): 295-306.
-
(1999)
J Cell Biol
, vol.147
, Issue.2
, pp. 295-306
-
-
Furuno, N.1
den Elzen, N.2
Pines, J.3
-
31
-
-
0033601783
-
Nuclear import of Cdk/cyclin complexes: Identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1
-
Moore JD, Yang J, Truant R, Kornbluth S (1999) Nuclear import of Cdk/cyclin complexes: Identification of distinct mechanisms for import of Cdk2/cyclin E and Cdc2/cyclin B1. J Cell Biol 144(2): 213-224.
-
(1999)
J Cell Biol
, vol.144
, Issue.2
, pp. 213-224
-
-
Moore, J.D.1
Yang, J.2
Truant, R.3
Kornbluth, S.4
-
32
-
-
0032983166
-
All aboard the cyclin train: Subcellular trafficking of cyclins and their CDK partners
-
Yang J, Kornbluth S (1999) All aboard the cyclin train: Subcellular trafficking of cyclins and their CDK partners. Trends Cell Biol 9(6): 207-210.
-
(1999)
Trends Cell Biol
, vol.9
, Issue.6
, pp. 207-210
-
-
Yang, J.1
Kornbluth, S.2
-
33
-
-
0043066731
-
Regulating mammalian checkpoints through Cdc25 inactivation
-
Donzelli M, Draetta GF (2003) Regulating mammalian checkpoints through Cdc25 inactivation. EMBO Rep 4(7): 671-677.
-
(2003)
EMBO Rep
, vol.4
, Issue.7
, pp. 671-677
-
-
Donzelli, M.1
Draetta, G.F.2
-
34
-
-
0034641724
-
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, et al. (2000) Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A 97(19): 10389-10394.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, Issue.19
, pp. 10389-10394
-
-
Matsuoka, S.1
Rotman, G.2
Ogawa, A.3
Shiloh, Y.4
Tamai, K.5
-
35
-
-
17644432403
-
Chk1 is an essential kinase that is regulated by atr and required for the G(2)/M DNA damage checkpoint
-
Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, et al. (2000) Chk1 is an essential kinase that is regulated by atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 14(12): 1448-1459.
-
(2000)
Genes Dev
, vol.14
, Issue.12
, pp. 1448-1459
-
-
Liu, Q.1
Guntuku, S.2
Cui, X.S.3
Matsuoka, S.4
Cortez, D.5
-
36
-
-
0034967556
-
ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
-
Zhao H, Piwnica-Worms H (2001) ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 21(13): 4129-4139.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.13
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
37
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri A, Falck J, Lukas C, Bartek J, Smith GC, et al. (2006) ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol 8(1): 37-45.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.1
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
-
38
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez D, Guntuku S, Qin J, Elledge SJ (2001) ATR and ATRIP: Partners in checkpoint signaling. Science 294(5547): 1713-1716.
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
39
-
-
40549130342
-
CDC6: From DNA replication to cell cycle checkpoints and oncogenesis
-
Borlado LR, Mendez J (2008) CDC6: From DNA replication to cell cycle checkpoints and oncogenesis. Carcinogenesis 29(2): 237-243.
-
(2008)
Carcinogenesis
, vol.29
, Issue.2
, pp. 237-243
-
-
Borlado, L.R.1
Mendez, J.2
-
40
-
-
0037415724
-
Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1
-
Clay-Farrace L, Pelizon C, Santamaria D, Pines J, Laskey RA (2003) Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1. EMBO J 22(3): 704-712.
-
(2003)
EMBO J
, vol.22
, Issue.3
, pp. 704-712
-
-
Clay-Farrace, L.1
Pelizon, C.2
Santamaria, D.3
Pines, J.4
Laskey, R.A.5
-
41
-
-
34248594803
-
Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin
-
Hermand D, Nurse P (2007) Cdc18 enforces long-term maintenance of the S phase checkpoint by anchoring the Rad3-Rad26 complex to chromatin. Mol Cell 26(4): 553-563.
-
(2007)
Mol Cell
, vol.26
, Issue.4
, pp. 553-563
-
-
Hermand, D.1
Nurse, P.2
-
42
-
-
33645505026
-
The functional role of Cdc6 in SG2/ M in mammalian cells
-
Lau E, Zhu C, Abraham RT, Jiang W (2006) The functional role of Cdc6 in SG2/ M in mammalian cells. EMBO Rep 7(4): 425-430.
-
(2006)
EMBO Rep
, vol.7
, Issue.4
, pp. 425-430
-
-
Lau, E.1
Zhu, C.2
Abraham, R.T.3
Jiang, W.4
-
43
-
-
60349103496
-
ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells
-
Liu L, Choi JH, Yim H, Choi JS, Park BD, et al. (2009) ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells. Int J Biochem Cell Biol 41(6): 1410-1420.
-
(2009)
Int J Biochem Cell Biol
, vol.41
, Issue.6
, pp. 1410-1420
-
-
Liu, L.1
Choi, J.H.2
Yim, H.3
Choi, J.S.4
Park, B.D.5
-
44
-
-
2142808749
-
The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation
-
Oehlmann M, Score AJ, Blow JJ (2004) The role of Cdc6 in ensuring complete genome licensing and S phase checkpoint activation. J Cell Biol 165(2): 181-190.
-
(2004)
J Cell Biol
, vol.165
, Issue.2
, pp. 181-190
-
-
Oehlmann, M.1
Score, A.J.2
Blow, J.J.3
-
45
-
-
25144525540
-
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis
-
Mailand N, Diffley JF (2005) CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis. Cell 122(6): 915-926.
-
(2005)
Cell
, vol.122
, Issue.6
, pp. 915-926
-
-
Mailand, N.1
Diffley, J.F.2
-
46
-
-
2542429354
-
Loss of geminin induces rereplication in the presence of functional p53
-
Melixetian M, Ballabeni A, Masiero L, Gasparini P, Zamponi R, et al. (2004) Loss of geminin induces rereplication in the presence of functional p53. J Cell Biol 165(4): 473-482.
-
(2004)
J Cell Biol
, vol.165
, Issue.4
, pp. 473-482
-
-
Melixetian, M.1
Ballabeni, A.2
Masiero, L.3
Gasparini, P.4
Zamponi, R.5
-
47
-
-
49649103584
-
Cdc6 determines utilization of p21(WAF1/CIP1)-dependent damage checkpoint in S phase cells
-
Kan Q, Jinno S, Kobayashi K, Yamamoto H, Okayama H (2008) Cdc6 determines utilization of p21(WAF1/CIP1)-dependent damage checkpoint in S phase cells. J Biol Chem 283(26): 17864-17872.
-
(2008)
J Biol Chem
, vol.283
, Issue.26
, pp. 17864-17872
-
-
Kan, Q.1
Jinno, S.2
Kobayashi, K.3
Yamamoto, H.4
Okayama, H.5
-
48
-
-
42449133406
-
ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6
-
Kan Q, Jinno S, Yamamoto H, Kobayashi K, Okayama H (2008) ATP-dependent activation of p21WAF1/CIP1-associated Cdk2 by Cdc6. Proc Natl Acad Sci U S A 105(12): 4757-4762.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.12
, pp. 4757-4762
-
-
Kan, Q.1
Jinno, S.2
Yamamoto, H.3
Kobayashi, K.4
Okayama, H.5
-
49
-
-
70349307378
-
Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival
-
JiangW
-
Lau E, Chiang GG, Abraham RT, JiangW (2009) Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival. Mol Biol Cell 20(17): 3953-3964.
-
(2009)
Mol Biol Cell
, vol.20
, Issue.17
, pp. 3953-3964
-
-
Lau, E.1
Chiang, G.G.2
Abraham, R.T.3
-
50
-
-
67649329182
-
Origin licensing and p53 status regulate Cdk2 activity during G(1)
-
Nevis KR, Cordeiro-Stone M, Cook JG (2009) Origin licensing and p53 status regulate Cdk2 activity during G(1). Cell Cycle 8(12): 1952-1963.
-
(2009)
Cell Cycle
, vol.8
, Issue.12
, pp. 1952-1963
-
-
Nevis, K.R.1
Cordeiro-Stone, M.2
Cook, J.G.3
-
51
-
-
73849132639
-
-
Yoshida K, Sugimoto N, Iwahori S, Yugawa T, Narisawa-Saito M, et al. (2010) CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells. J Cell Sci 123(Pt 2): 225-235.
-
Yoshida K, Sugimoto N, Iwahori S, Yugawa T, Narisawa-Saito M, et al. (2010) CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells. J Cell Sci 123(Pt 2): 225-235.
-
-
-
-
52
-
-
0242610832
-
Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells
-
Feng D, Tu Z, Wu W, Liang C (2003) Inhibiting the expression of DNA replication-initiation proteins induces apoptosis in human cancer cells. Cancer Res 63(21): 7356-7364.
-
(2003)
Cancer Res
, vol.63
, Issue.21
, pp. 7356-7364
-
-
Feng, D.1
Tu, Z.2
Wu, W.3
Liang, C.4
-
53
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
Cimprich KA, Cortez D (2008) ATR: An essential regulator of genome integrity. Nat Rev Mol Cell Biol 9(8): 616-627.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.8
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
54
-
-
73349088472
-
Functional genomic screens identify CINP as a genome maintenance protein
-
Lovejoy CA, Xu X, Bansbach CE, Glick GG, Zhao R, et al. (2009) Functional genomic screens identify CINP as a genome maintenance protein. Proc Natl Acad Sci U S A 106(46): 19304-19309.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.46
, pp. 19304-19309
-
-
Lovejoy, C.A.1
Xu, X.2
Bansbach, C.E.3
Glick, G.G.4
Zhao, R.5
-
55
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis TD, Gorgoulis VG, Bartek J (2008) An oncogene-induced DNA damage model for cancer development. Science 319(5868): 1352-1355.
-
(2008)
Science
, vol.319
, Issue.5868
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
56
-
-
36749022214
-
The DNA damage response: Ten years after
-
Harper JW, Elledge SJ (2007) The DNA damage response: Ten years after. Mol Cell 28(5): 739-745.
-
(2007)
Mol Cell
, vol.28
, Issue.5
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
57
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan MB, Bartek J (2004) Cell-cycle checkpoints and cancer. Nature 432(7015): 316-323.
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
58
-
-
28544435657
-
Improved methods for the generation of human gene knockout and knockin cell lines
-
Topaloglu O, Hurley PJ, Yildirim O, Civin CI, Bunz F (2005) Improved methods for the generation of human gene knockout and knockin cell lines. Nucleic Acids Res 33(18): e158.
-
(2005)
Nucleic Acids Res
, vol.33
, Issue.18
-
-
Topaloglu, O.1
Hurley, P.J.2
Yildirim, O.3
Civin, C.I.4
Bunz, F.5
-
59
-
-
39149117397
-
Genetic knockouts and knockins in human somatic cells
-
Rago C, Vogelstein B, Bunz F (2007) Genetic knockouts and knockins in human somatic cells. Nat Protoc 2(11): 2734-2746.
-
(2007)
Nat Protoc
, vol.2
, Issue.11
, pp. 2734-2746
-
-
Rago, C.1
Vogelstein, B.2
Bunz, F.3
-
60
-
-
30944435598
-
Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response
-
Smits VA, Reaper PM, Jackson SP (2006) Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response. Curr Biol 16(2): 150-159.
-
(2006)
Curr Biol
, vol.16
, Issue.2
, pp. 150-159
-
-
Smits, V.A.1
Reaper, P.M.2
Jackson, S.P.3
-
61
-
-
4444321565
-
Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells
-
van Vugt MA, Bras A, Medema RH (2004) Polo-like kinase-1 controls recovery from a G2 DNA damage-induced arrest in mammalian cells. Mol Cell 15(5): 799-811.
-
(2004)
Mol Cell
, vol.15
, Issue.5
, pp. 799-811
-
-
van Vugt, M.A.1
Bras, A.2
Medema, R.H.3
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