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Volumn 77, Issue 6, 2003, Pages 3495-3504

Genetic fate of recombinant adeno-associated virus vector genomes in muscle

Author keywords

[No Author keywords available]

Indexed keywords

EXONUCLEASE; VIRUS VECTOR;

EID: 0037333815     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.6.3495-3504.2003     Document Type: Article
Times cited : (222)

References (61)
  • 2
    • 0029817995 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors
    • Bertran, J., J. L. Miller, Y. Yang, A. Fenimore-Justman, F. Rueda, E. F. Vanin, and A. W. Nienhuis. 1996. Recombinant adeno-associated virus-mediated high-efficiency, transient expression of the murine cationic amino acid transporter (ecotropic retroviral receptor) permits stable transduction of human HeLa cells by ecotropic retroviral vectors. J. Virol. 70:6759-6766.
    • (1996) J. Virol. , vol.70 , pp. 6759-6766
    • Bertran, J.1    Miller, J.L.2    Yang, Y.3    Fenimore-Justman, A.4    Rueda, F.5    Vanin, E.F.6    Nienhuis, A.W.7
  • 3
    • 0035025888 scopus 로고    scopus 로고
    • A quantitative assay for HIV DNA integration in vivo
    • Butler, S. L., M. S. Hansen, and F. D. Bushman. 2001. A quantitative assay for HIV DNA integration in vivo. Nat. Med. 7:631-634.
    • (2001) Nat. Med. , vol.7 , pp. 631-634
    • Butler, S.L.1    Hansen, M.S.2    Bushman, F.D.3
  • 4
    • 0034182612 scopus 로고    scopus 로고
    • In vivo selection of hepatocytes transduced with adeno-associated viral vectors
    • Chen, S. J., J. Tazelaar, A. D. Moscioni, and J. M. Wilson. 2000. In vivo selection of hepatocytes transduced with adeno-associated viral vectors. Mol. Ther. 1:414-422.
    • (2000) Mol. Ther. , vol.1 , pp. 414-422
    • Chen, S.J.1    Tazelaar, J.2    Moscioni, A.D.3    Wilson, J.M.4
  • 5
    • 0032853699 scopus 로고    scopus 로고
    • Immune responses to adenovirus and adeno-associated virus in humans
    • Chirmule, N., K. Propert, S. Magosin, Y. Qian, R. Qian, and J. Wilson. 1999. Immune responses to adenovirus and adeno-associated virus in humans. Gene Ther. 6:1574-1583.
    • (1999) Gene Ther. , vol.6 , pp. 1574-1583
    • Chirmule, N.1    Propert, K.2    Magosin, S.3    Qian, Y.4    Qian, R.5    Wilson, J.6
  • 6
    • 0033541640 scopus 로고    scopus 로고
    • Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses
    • Clark, K. R., X. Liu, J. P. McGrath, and P. R. Johnson. 1999. Highly purified recombinant adeno-associated virus vectors are biologically active and free of detectable helper and wild-type viruses. Hum. Gene Ther. 10:1031-1039.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 1031-1039
    • Clark, K.R.1    Liu, X.2    McGrath, J.P.3    Johnson, P.R.4
  • 7
    • 0030970938 scopus 로고    scopus 로고
    • Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle
    • Clark, K. R., T. J. Sferra, and P. R. Johnson. 1997. Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle. Hum. Gene Ther. 8:659-669.
    • (1997) Hum. Gene Ther. , vol.8 , pp. 659-669
    • Clark, K.R.1    Sferra, T.J.2    Johnson, P.R.3
  • 8
    • 0033389722 scopus 로고    scopus 로고
    • Gene transfer into the CNS using recombinant adeno-associated virus: Analysis of vector DNA forms resulting in sustained expression
    • Clark, K. R., T. J. Sferra, W. Lo, G. Qu, R. Chen, and P. R. Johnson. 1999. Gene transfer into the CNS using recombinant adeno-associated virus: analysis of vector DNA forms resulting in sustained expression. J. Drug Target. 7:269-283.
    • (1999) J. Drug Target. , vol.7 , pp. 269-283
    • Clark, K.R.1    Sferra, T.J.2    Lo, W.3    Qu, G.4    Chen, R.5    Johnson, P.R.6
  • 9
    • 0028889443 scopus 로고
    • Cell lines for the production of recombinant adeno-associated virus
    • Clark, K. R., F. Voulgaropoulou, D. M. Fraley, and P. R. Johnson. 1995. Cell lines for the production of recombinant adeno-associated virus. Hum. Gene Ther. 6:1329-1341.
    • (1995) Hum. Gene Ther. , vol.6 , pp. 1329-1341
    • Clark, K.R.1    Voulgaropoulou, F.2    Fraley, D.M.3    Johnson, P.R.4
  • 10
    • 0017085802 scopus 로고
    • A colony bank containing synthetic Col El hybrid plasmids representative of the entire E. coli genome
    • Clarke, L., and J. Carbon. 1976. A colony bank containing synthetic Col El hybrid plasmids representative of the entire E. coli genome. Cell 9:91-99.
    • (1976) Cell , vol.9 , pp. 91-99
    • Clarke, L.1    Carbon, J.2
  • 11
    • 0028157494 scopus 로고
    • Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo
    • International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3
    • Cole, J., and T. R. Skopek. 1994. International Commission for Protection Against Environmental Mutagens and Carcinogens. Working paper no. 3. Somatic mutant frequency, mutation rates and mutational spectra in the human population in vivo. Mutat. Res. 304:33-105.
    • (1994) Mutat. Res. , vol.304 , pp. 33-105
    • Cole, J.1    Skopek, T.R.2
  • 12
    • 0028000241 scopus 로고
    • Direct gene transfer into muscle
    • Danko, I., and J. A. Wolff. 1994. Direct gene transfer into muscle. Vaccine 12:1499-1502.
    • (1994) Vaccine , vol.12 , pp. 1499-1502
    • Danko, I.1    Wolff, J.A.2
  • 13
    • 0031691257 scopus 로고    scopus 로고
    • Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
    • Duan, D., P. Sharma, J. Yang, Y. Yue, L. Dudus, Y. Zhang, K. J. Fisher, and J. F. Engelhardt. 1998. Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J. Virol. 72:8568-8577.
    • (1998) J. Virol. , vol.72 , pp. 8568-8577
    • Duan, D.1    Sharma, P.2    Yang, J.3    Yue, Y.4    Dudus, L.5    Zhang, Y.6    Fisher, K.J.7    Engelhardt, J.F.8
  • 14
    • 0024978864 scopus 로고
    • Cationic liposome-mediated transfection
    • Felgner, P. L., and G. M. Ringold. 1989. Cationic liposome-mediated transfection. Nature 337:387-388.
    • (1989) Nature , vol.337 , pp. 387-388
    • Felgner, P.L.1    Ringold, G.M.2
  • 18
    • 0028783719 scopus 로고
    • Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome
    • Giraud, C., E. Winocour, and K. I. Berns. 1995. Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome. J. Virol. 69:6917-6924.
    • (1995) J. Virol. , vol.69 , pp. 6917-6924
    • Giraud, C.1    Winocour, E.2    Berns, K.I.3
  • 19
    • 0002025785 scopus 로고
    • Manipulation of adenovirus vectors
    • Graham, F. L., and L. Prevec. 1991. Manipulation of adenovirus vectors. Methods Mol. Biol. 7:109-128.
    • (1991) Methods Mol. Biol. , vol.7 , pp. 109-128
    • Graham, F.L.1    Prevec, L.2
  • 20
    • 0033056699 scopus 로고    scopus 로고
    • Frequency and stability of chromosomal integration of adenovirus vectors
    • Harui, A., S. Suzuki, S. Kochanek, and K. Mitani. 1999, Frequency and stability of chromosomal integration of adenovirus vectors. J. Virol. 73:6141-6146.
    • (1999) J. Virol. , vol.73 , pp. 6141-6146
    • Harui, A.1    Suzuki, S.2    Kochanek, S.3    Mitani, K.4
  • 21
    • 0021690155 scopus 로고
    • Use of adeno-associated virus as a mammalian DNA cloning vector: Transduction of neomycin resistance into mammalian tissue culture cells
    • Hermonat, P. L., and N. Muzyczka. 1984, Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells. Proc. Natl. Acad. Sci. USA 81:6466-6470.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 6466-6470
    • Hermonat, P.L.1    Muzyczka, N.2
  • 22
    • 0032826773 scopus 로고    scopus 로고
    • Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model
    • Hernandez, Y. J., J. Wang, W. G. Kearns, S. Loiler, A. Poirier, and T. R. Flotte. 1999. Latent adeno-associated virus infection elicits humoral but not cell-mediated immune responses in a nonhuman primate model. J. Virol. 73:8549-8558.
    • (1999) J. Virol. , vol.73 , pp. 8549-8558
    • Hernandez, Y.J.1    Wang, J.2    Kearns, W.G.3    Loiler, S.4    Poirier, A.5    Flotte, T.R.6
  • 23
    • 0035793325 scopus 로고    scopus 로고
    • Gene transfer as an approach to treating hemophilia
    • High, K. A. 2001. Gene transfer as an approach to treating hemophilia. Circ. Res. 88:137-144.
    • (2001) Circ. Res. , vol.88 , pp. 137-144
    • High, K.A.1
  • 24
    • 0028285126 scopus 로고
    • The immunobiology of muscle
    • Hohlfeld, R., and A. G. Engel. 1994. The immunobiology of muscle. Immunol. Today 15:269-274.
    • (1994) Immunol. Today , vol.15 , pp. 269-274
    • Hohlfeld, R.1    Engel, A.G.2
  • 25
    • 0033819583 scopus 로고    scopus 로고
    • Evolutionary history of B1 retroposons in the genus Mus
    • Kass, D. H., M. E. Raynor, and T. M. Williams. 2000. Evolutionary history of B1 retroposons in the genus Mus. J. Mol. Evol. 51:256-264.
    • (2000) J. Mol. Evol. , vol.51 , pp. 256-264
    • Kass, D.H.1    Raynor, M.E.2    Williams, T.M.3
  • 27
    • 0029836472 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus (AAV-CFTR) vectors do not integrate in a site-specific fashion in an immortalized epithelial cell line
    • Kearns, W. G., S. A. Afione, S. B. Fulmer, M. C. Pang, D. Erikson, M. Egan, M. J. Landrum, T. R. Flotte, and G. R. Cutting. 1996. Recombinant adeno-associated virus (AAV-CFTR) vectors do not integrate in a site-specific fashion in an immortalized epithelial cell line. Gene Ther. 3:748-755.
    • (1996) Gene Ther. , vol.3 , pp. 748-755
    • Kearns, W.G.1    Afione, S.A.2    Fulmer, S.B.3    Pang, M.C.4    Erikson, D.5    Egan, M.6    Landrum, M.J.7    Flotte, T.R.8    Cutting, G.R.9
  • 28
    • 0031019819 scopus 로고    scopus 로고
    • Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors
    • Koeberl, D. D., I. E. Alexander, C. L. Halbert, D. W. Russell, and A. D. Miller. 1997. Persistent expression of human clotting factor IX from mouse liver after intravenous injection of adeno-associated virus vectors. Proc. Natl. Acad. Sci. USA 94:1426-1431.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1426-1431
    • Koeberl, D.D.1    Alexander, I.E.2    Halbert, C.L.3    Russell, D.W.4    Miller, A.D.5
  • 30
    • 0023731951 scopus 로고
    • Adeno-associated virus: A vector system for efficient introduction and integration of DNA into a variety of mammalian cell types
    • Lebkowski, J. S., M. M. McNally, T. B. Okarma, and L. B. Lerch. 1988. Adeno-associated virus: a vector system for efficient introduction and integration of DNA into a variety of mammalian cell types. Mol. Cell. Biol. 8:3988-3996.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3988-3996
    • Lebkowski, J.S.1    McNally, M.M.2    Okarma, T.B.3    Lerch, L.B.4
  • 34
    • 0031058475 scopus 로고    scopus 로고
    • Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line
    • Malik, P., S. A. McQuiston, X. J. Yu, K. A. Pepper, W. J. Krall, G. M. Podsakoff, G. J. Kurtzman, and D. B. Kohn. 1997. Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line. J. Virol. 71:1776-1783.
    • (1997) J. Virol. , vol.71 , pp. 1776-1783
    • Malik, P.1    McQuiston, S.A.2    Yu, X.J.3    Pepper, K.A.4    Krall, W.J.5    Podsakoff, G.M.6    Kurtzman, G.J.7    Kohn, D.B.8
  • 35
    • 0033586277 scopus 로고    scopus 로고
    • Plasmid DNA malaria vaccine: The potential for genomic integration after intramuscular injection
    • Martin, T., S. Parker, R. Hedstrom, T. Le, S. Hoffman, J. Norman, P. Hobart, and D. Lew. 1999. Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection. Hum. Gene Ther. 10:759-768.
    • (1999) Hum. Gene Ther. , vol.10 , pp. 759-768
    • Martin, T.1    Parker, S.2    Hedstrom, R.3    Le, T.4    Hoffman, S.5    Norman, J.6    Hobart, P.7    Lew, D.8
  • 36
    • 0023889191 scopus 로고
    • Adeno-associated virus general transduction vectors: Analysis of proviral structures
    • McLaughlin, S. K., P. Collis, P. L. Hermonat, and N. Muzyczka. 1988. Adeno-associated virus general transduction vectors: analysis of proviral structures. J. Virol. 62:1963-1973.
    • (1988) J. Virol. , vol.62 , pp. 1963-1973
    • McLaughlin, S.K.1    Collis, P.2    Hermonat, P.L.3    Muzyczka, N.4
  • 38
    • 0036478954 scopus 로고    scopus 로고
    • Chromosomal effects of adeno-associated virus vector integration
    • Miller, D. G., E. A. Rutledge, and D. W. Russell. 2002. Chromosomal effects of adeno-associated virus vector integration. Nat. Genet. 30:147-148.
    • (2002) Nat. Genet. , vol.30 , pp. 147-148
    • Miller, D.G.1    Rutledge, E.A.2    Russell, D.W.3
  • 39
    • 0033761804 scopus 로고    scopus 로고
    • Adeno-associated virus vectors for gene therapy: More pros than cons?
    • Monahan, P. E., and R. J. Samulski. 2000. Adeno-associated virus vectors for gene therapy: more pros than cons? Mol. Med. Today 6:433-440.
    • (2000) Mol. Med. Today , vol.6 , pp. 433-440
    • Monahan, P.E.1    Samulski, R.J.2
  • 40
    • 0032990410 scopus 로고    scopus 로고
    • Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver
    • Nakai, H., Y. Iwaki, M. A. Kay, and L. B. Couto. 1999. Isolation of recombinant adeno-associated virus vector-cellular DNA junctions from mouse liver. J. Virol. 73:5438-5447.
    • (1999) J. Virol. , vol.73 , pp. 5438-5447
    • Nakai, H.1    Iwaki, Y.2    Kay, M.A.3    Couto, L.B.4
  • 41
    • 0033814178 scopus 로고    scopus 로고
    • Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo
    • Nakai, H., T. A. Storm, and M. A. Kay. 2000. Recruitment of single-stranded recombinant adeno-associated virus vector genomes and intermolecular recombination are responsible for stable transduction of liver in vivo. J. Virol. 74:9451-9463.
    • (2000) J. Virol. , vol.74 , pp. 9451-9463
    • Nakai, H.1    Storm, T.A.2    Kay, M.A.3
  • 42
    • 0034960344 scopus 로고    scopus 로고
    • Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo
    • Nakai, H., S. R. Yant, T. A. Storm, S. Fuess, L. Meuse, and M. A. Kay. 2001. Extrachromosomal recombinant adeno-associated virus vector genomes are primarily responsible for stable liver transduction in vivo. J. Virol. 75:6969-6976.
    • (2001) J. Virol. , vol.75 , pp. 6969-6976
    • Nakai, H.1    Yant, S.R.2    Storm, T.A.3    Fuess, S.4    Meuse, L.5    Kay, M.A.6
  • 43
    • 0030773872 scopus 로고    scopus 로고
    • Adeno-associated virus vector integration junctions
    • Rutledge, E. A., and D. W. Russell. 1997. Adeno-associated virus vector integration junctions. J. Virol. 71:8429-8436.
    • (1997) J. Virol. , vol.71 , pp. 8429-8436
    • Rutledge, E.A.1    Russell, D.W.2
  • 47
    • 0034828903 scopus 로고    scopus 로고
    • Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors
    • Song, S., J. Embury, P. J. Laipis, K. I. Berns, J. M. Crawford, and T. R. Flotte. 2001. Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectors. Gene Ther. 8:1299-1306.
    • (2001) Gene Ther. , vol.8 , pp. 1299-1306
    • Song, S.1    Embury, J.2    Laipis, P.J.3    Berns, K.I.4    Crawford, J.M.5    Flotte, T.R.6
  • 48
    • 0035957384 scopus 로고    scopus 로고
    • Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle
    • Song, S., P. J. Laipis, K. I. Berns, and T. R. Flotte. 2001. Effect of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle. Proc. Natl. Acad. Sci. USA 98:4084-4088.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 4084-4088
    • Song, S.1    Laipis, P.J.2    Berns, K.I.3    Flotte, T.R.4
  • 49
    • 0025367722 scopus 로고
    • Overview of biological effects of addition of DNA molecules to cells
    • Temin, H. M. 1990. Overview of biological effects of addition of DNA molecules to cells. J. Med. Virol. 31:13-17.
    • (1990) J. Med. Virol. , vol.31 , pp. 13-17
    • Temin, H.M.1
  • 50
    • 0022226995 scopus 로고
    • Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cells
    • Tratschin, J. D., I. L. Miller, M. G. Smith, and B. J. Carter. 1985. Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cells. Mol. Cell. Biol. 5:3251-3260.
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 3251-3260
    • Tratschin, J.D.1    Miller, I.L.2    Smith, M.G.3    Carter, B.J.4
  • 51
    • 0033023881 scopus 로고    scopus 로고
    • Structure of adeno-associated virus vector DNA following transduction of the skeletal muscle
    • Vincent-Lacaze, N., R. O. Snyder, R. Gluzman, D. Bohl, C. Lagarde, and O. Danos. 1999. Structure of adeno-associated virus vector DNA following transduction of the skeletal muscle. J. Virol. 73:1949-1955.
    • (1999) J. Virol. , vol.73 , pp. 1949-1955
    • Vincent-Lacaze, N.1    Snyder, R.O.2    Gluzman, R.3    Bohl, D.4    Lagarde, C.5    Danos, O.6
  • 54
    • 0023552653 scopus 로고
    • Oligonucleotide probes for the screening of recombinant DNA libraries
    • S. L. Berger and A. R Kimmel (ed.). Harcourt Brace Janovich Publishers, San Diego, Calif.
    • Wallace, B., and C. Miyada. 1987. Oligonucleotide probes for the screening of recombinant DNA libraries, p. 432-442. In S. L. Berger and A. R Kimmel (ed.), Guide to molecular cloning techniques. Harcourt Brace Janovich Publishers, San Diego, Calif.
    • (1987) Guide to Molecular Cloning Techniques , pp. 432-442
    • Wallace, B.1    Miyada, C.2
  • 55
    • 0026660060 scopus 로고
    • Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector
    • Walsh, C. E., J. M. Liu, X. Xiao, N. S. Young, A. W. Nienhuis, and R. J. Samulski. 1992. Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proc. Natl. Acad. Sci. USA 89:7257-7261.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 7257-7261
    • Walsh, C.E.1    Liu, J.M.2    Xiao, X.3    Young, N.S.4    Nienhuis, A.W.5    Samulski, R.J.6
  • 56
    • 0028307303 scopus 로고
    • Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA
    • Weitzman, M. D., S. R. Kyostio, R. M. Kotin, and R. A. Owens. 1994. Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA. Proc. Natl. Acad. Sci. USA 91:5808-5812.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5808-5812
    • Weitzman, M.D.1    Kyostio, S.R.2    Kotin, R.M.3    Owens, R.A.4
  • 57
    • 0031779697 scopus 로고    scopus 로고
    • Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets
    • Wu, P., M. I. Phillips, J. Bui, and E. F. Terwilliger. 1998. Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets. J. Virol. 72:5919-5926.
    • (1998) J. Virol. , vol.72 , pp. 5919-5926
    • Wu, P.1    Phillips, M.I.2    Bui, J.3    Terwilliger, E.F.4
  • 58
    • 0028356571 scopus 로고
    • Plasmid integration, amplification and cytogenetics in CHO cells: Questions and comments
    • Wurm, F. M., and C. J. Petropoulos. 1994. Plasmid integration, amplification and cytogenetics in CHO cells: questions and comments. Biologicals 22:95-102.
    • (1994) Biologicals , vol.22 , pp. 95-102
    • Wurm, F.M.1    Petropoulos, C.J.2
  • 59
    • 0029843596 scopus 로고    scopus 로고
    • Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector
    • Xiao, X., J. Li, and R. J. Samulski. 1996. Efficient long-term gene transfer into muscle tissue of immunocompetent mice by adeno-associated virus vector. J. Virol. 70:8098-8108.
    • (1996) J. Virol. , vol.70 , pp. 8098-8108
    • Xiao, X.1    Li, J.2    Samulski, R.J.3
  • 60
    • 0030827586 scopus 로고    scopus 로고
    • Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro
    • Yang, C. C., X. Xiao, X. Zhu, D. C. Ansardi, N. D. Epstein, M. R. Frey, A. G. Matera, and R. J. Samulski. 1997. Cellular recombination pathways and viral terminal repeat hairpin structures are sufficient for adeno-associated virus integration in vivo and in vitro. J. Virol. 71:9231-9247.
    • (1997) J. Virol. , vol.71 , pp. 9231-9247
    • Yang, C.C.1    Xiao, X.2    Zhu, X.3    Ansardi, D.C.4    Epstein, N.D.5    Frey, M.R.6    Matera, A.G.7    Samulski, R.J.8
  • 61
    • 0032862285 scopus 로고    scopus 로고
    • Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination
    • Yang, J., W. Zhou, Y. Zhang, T. Zidon, T. Ritchie, and J. F. Engelhardt. 1999. Concatamerization of adeno-associated virus circular genomes occurs through intermolecular recombination. J. Virol. 73:9468-9477.
    • (1999) J. Virol. , vol.73 , pp. 9468-9477
    • Yang, J.1    Zhou, W.2    Zhang, Y.3    Zidon, T.4    Ritchie, T.5    Engelhardt, J.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.