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Volumn 26, Issue 3, 2015, Pages 359-370

Role of protein kinase A in regulating mitochondrial function and neuronal development: Implications to neurodegenerative diseases

Author keywords

A kinase anchoring proteins; dendrites; mitochondrial dynamics; mitochondrial trafficking; neurodegeneration; protein kinase A

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; DOPAMINE; SCAFFOLD PROTEIN;

EID: 84930163256     PISSN: 03341763     EISSN: 21910200     Source Type: Journal    
DOI: 10.1515/revneuro-2014-0085     Document Type: Article
Times cited : (61)

References (85)
  • 2
    • 45849142182 scopus 로고    scopus 로고
    • CAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons
    • Aglah, C., Gordon, T., and Posse de Chaves, E. I. (2008). cAMP promotes neurite outgrowth and extension through protein kinase A but independently of Erk activation in cultured rat motoneurons. Neuropharmacology 55, 8-17.
    • (2008) Neuropharmacology , vol.55 , pp. 8-17
    • Aglah, C.1    Gordon, T.2    Posse De Chaves, E.I.3
  • 3
    • 0037135975 scopus 로고    scopus 로고
    • Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics
    • Alto, N. M., Soderling, J., and Scott, J. D. (2002). Rab32 is an A-kinase anchoring protein and participates in mitochondrial dynamics. J. Cell. Biol. 158, 659-668.
    • (2002) J. Cell. Biol. , vol.158 , pp. 659-668
    • Alto, N.M.1    Soderling, J.2    Scott, J.D.3
  • 4
    • 0033803750 scopus 로고    scopus 로고
    • PKA phosphorylations on tau: Developmental studies in the mouse
    • Andorfer, C. A. and Davies, P. (2000). PKA phosphorylations on tau: developmental studies in the mouse. Dev. Neurosci. 22, 303-309.
    • (2000) Dev. Neurosci. , vol.22 , pp. 303-309
    • Andorfer, C.A.1    Davies, P.2
  • 6
    • 84906861963 scopus 로고    scopus 로고
    • Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
    • Ashrafi, G., Schlehe, J. S., LaVoie, M. J., and Schwarz, T. L. (2014). Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin. J. Cell. Biol. 206, 655-670.
    • (2014) J. Cell. Biol. , vol.206 , pp. 655-670
    • Ashrafi, G.1    Schlehe, J.S.2    Lavoie, M.J.3    Schwarz, T.L.4
  • 8
    • 33745759912 scopus 로고    scopus 로고
    • Pharmacological management of Huntington's disease: An evidence-based review
    • Bonelli, R. M. and Wenning, G. K. (2006). Pharmacological management of Huntington's disease: an evidence-based review. Curr. Pharm. Des. 12, 2701-2720.
    • (2006) Curr. Pharm. Des. , vol.12 , pp. 2701-2720
    • Bonelli, R.M.1    Wenning, G.K.2
  • 13
    • 67650394253 scopus 로고    scopus 로고
    • A-kinase anchoring proteins: From protein complexes to physiology and disease
    • Carnegie, G. K., Means, C. K., and Scott, J. D. (2009). A-kinase anchoring proteins: from protein complexes to physiology and disease. IUBMB Life 61, 394-406.
    • (2009) IUBMB Life , vol.61 , pp. 394-406
    • Carnegie, G.K.1    Means, C.K.2    Scott, J.D.3
  • 14
    • 34547944617 scopus 로고    scopus 로고
    • A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a
    • Chai, S., Li, M., Lan, J., Xiong, Z. G., Saugstad, J. A., and Simon, R. P. (2007). A kinase-anchoring protein 150 and calcineurin are involved in regulation of acid-sensing ion channels ASIC1a and ASIC2a. J. Biol. Chem. 282, 22668-22677.
    • (2007) J. Biol. Chem. , vol.282 , pp. 22668-22677
    • Chai, S.1    Li, M.2    Lan, J.3    Xiong, Z.G.4    Saugstad, J.A.5    Simon, R.P.6
  • 15
    • 33745863454 scopus 로고    scopus 로고
    • Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells
    • Chalovich, E. M., Zhu, J. H., Caltagarone, J., Bowser, R., and Chu, C. T. (2006). Functional repression of cAMP response element in 6-hydroxydopamine-treated neuronal cells. J. Biol. Chem. 281, 17870-17881.
    • (2006) J. Biol. Chem. , vol.281 , pp. 17870-17881
    • Chalovich, E.M.1    Zhu, J.H.2    Caltagarone, J.3    Bowser, R.4    Chu, C.T.5
  • 16
    • 69949174646 scopus 로고    scopus 로고
    • The PKARI subunit of protein kinase A modulates the activation of p90RSK1 and its function
    • Chaturvedi, D., Cohen, M. S., Taunton, J., and Patel, T. B. (2009). The PKARI subunit of protein kinase A modulates the activation of p90RSK1 and its function. J. Biol. Chem. 284, 23670-23681.
    • (2009) J. Biol. Chem. , vol.284 , pp. 23670-23681
    • Chaturvedi, D.1    Cohen, M.S.2    Taunton, J.3    Patel, T.B.4
  • 17
    • 44149124887 scopus 로고    scopus 로고
    • Autophagy in neuroprotection and neurodegeneration: A question of balance
    • Cherra, S. J. and Chu, C. T. (2008). Autophagy in neuroprotection and neurodegeneration: a question of balance. Future Neurol. 3, 309-323.
    • (2008) Future Neurol. , vol.3 , pp. 309-323
    • Cherra, S.J.1    Chu, C.T.2
  • 19
    • 22244442489 scopus 로고    scopus 로고
    • The biochemistry of Parkinson's disease
    • Cookson, M. R. (2005). The biochemistry of Parkinson's disease. Annu. Rev. Biochem. 74, 29-52.
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 29-52
    • Cookson, M.R.1
  • 20
    • 84921631695 scopus 로고    scopus 로고
    • Developmental shaping of dendritic arbors in Drosophila relies on tightly regulated intra-neuronal activity of protein kinase A (PKA)
    • Copf, T. (2014). Developmental shaping of dendritic arbors in Drosophila relies on tightly regulated intra-neuronal activity of protein kinase A (PKA). Dev. Biol. 393, 282-297.
    • (2014) Dev. Biol. , vol.393 , pp. 282-297
    • Copf, T.1
  • 21
    • 60249095382 scopus 로고    scopus 로고
    • The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit B2 antagonizes neuronal survival by promoting mitochondrial fission
    • Dagda, R. K., Merrill, R. A., Cribbs, J. T., Chen, Y., Hell, J. W., Usachev, Y. M., and Strack, S. (2008). The spinocerebellar ataxia 12 gene product and protein phosphatase 2A regulatory subunit B2 antagonizes neuronal survival by promoting mitochondrial fission. J. Biol. Chem. 283, 36241-48.
    • (2008) J. Biol. Chem. , vol.283 , pp. 36241-36248
    • Dagda, R.K.1    Merrill, R.A.2    Cribbs, J.T.3    Chen, Y.4    Hell, J.W.5    Usachev, Y.M.6    Strack, S.7
  • 22
    • 81155128499 scopus 로고    scopus 로고
    • Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
    • Dagda, R. K., Gusdon, A. M., Pien, I., Strack, S., Green, S., Li, C., Van Houten, B., Cherra, S. J., 3rd, and Chu, C. T. (2011). Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease. Cell Death Differ. 18, 1914-1923.
    • (2011) Cell Death Differ. , vol.18 , pp. 1914-1923
    • Dagda, R.K.1    Gusdon, A.M.2    Pien, I.3    Strack, S.4    Green, S.5    Li, C.6    Van Houten, B.7    Cherra, S.J.8    Chu, C.T.9
  • 24
    • 0033569750 scopus 로고    scopus 로고
    • The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons
    • Davare, M. A., Dong, F., Rubin, C. S., and Hell, J. W. (1999). The A-kinase anchor protein MAP2B and cAMP-dependent protein kinase are associated with class C L-type calcium channels in neurons. J. Biol. Chem. 274, 30280-30287.
    • (1999) J. Biol. Chem. , vol.274 , pp. 30280-30287
    • Davare, M.A.1    Dong, F.2    Rubin, C.S.3    Hell, J.W.4
  • 25
    • 71949090833 scopus 로고    scopus 로고
    • Mitochondrial trafficking of APP and synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases
    • Devi, L. and Anandatheerthavarada, H. K. (2010). Mitochondrial trafficking of APP and synuclein: relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases. Biochim. Biophys. Acta 1802, 11-19.
    • (2010) Biochim. Biophys. Acta , vol.1802 , pp. 11-19
    • Devi, L.1    Anandatheerthavarada, H.K.2
  • 26
    • 80155137546 scopus 로고    scopus 로고
    • PKA/AKAP1 and PP2A/B2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics
    • Dickey, A. S. and Strack, S. (2011). PKA/AKAP1 and PP2A/B2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. J. Neurosci. 31, 15716-15726.
    • (2011) J. Neurosci. , vol.31 , pp. 15716-15726
    • Dickey, A.S.1    Strack, S.2
  • 27
    • 70450233487 scopus 로고    scopus 로고
    • D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling
    • Eggers, C. T., Schafer, J. C., Goldenring, J. R., and Taylor, S. S. (2009). D-AKAP2 interacts with Rab4 and Rab11 through its RGS domains and regulates transferrin receptor recycling. J. Biol. Chem. 284, 32869-32880.
    • (2009) J. Biol. Chem. , vol.284 , pp. 32869-32880
    • Eggers, C.T.1    Schafer, J.C.2    Goldenring, J.R.3    Taylor, S.S.4
  • 28
    • 0035957525 scopus 로고    scopus 로고
    • The biological functions of A-kinase anchor proteins
    • Feliciello, A., Gottesman, M. E., and Avvedimento, E. V. (2001). The biological functions of A-kinase anchor proteins. J. Mol. Biol. 308, 99-114.
    • (2001) J. Mol. Biol. , vol.308 , pp. 99-114
    • Feliciello, A.1    Gottesman, M.E.2    Avvedimento, E.V.3
  • 30
    • 80053960641 scopus 로고    scopus 로고
    • Increased PKA signaling disrupts recognition memory and spatial memory: Role in Huntington's disease
    • Giralt, A., Saavedra, A., Carreton, O., Xifro, X., Alberch, J., and Perez-Navarro, E. (2011). Increased PKA signaling disrupts recognition memory and spatial memory: role in Huntington's disease. Hum. Mol. Genet. 20, 4232-4247.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 4232-4247
    • Giralt, A.1    Saavedra, A.2    Carreton, O.3    Xifro, X.4    Alberch, J.5    Perez-Navarro, E.6
  • 31
    • 0037104782 scopus 로고    scopus 로고
    • Regulation of A-kinase anchoring protein 79/150-cAMPdependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin
    • Gomez, L. L., Alam, S., Smith, K. E., Horne, E., and Dell'Acqua, M. L. (2002). Regulation of A-kinase anchoring protein 79/150-cAMPdependent protein kinase postsynaptic targeting by NMDA receptor activation of calcineurin and remodeling of dendritic actin. J. Neurosci. 22, 7027-7044.
    • (2002) J. Neurosci. , vol.22 , pp. 7027-7044
    • Gomez, L.L.1    Alam, S.2    Smith, K.E.3    Horne, E.4    Dell'Acqua, M.L.5
  • 32
    • 0027339043 scopus 로고
    • Overexpression of Ca2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility
    • Goshima, Y., Ohsako, S., and Yamauchi, T. (1993). Overexpression of Ca2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility. J. Neurosci. 13, 559-567.
    • (1993) J. Neurosci. , vol.13 , pp. 559-567
    • Goshima, Y.1    Ohsako, S.2    Yamauchi, T.3
  • 33
    • 79954603862 scopus 로고    scopus 로고
    • To eat or not to eat: Neuronal metabolism, mitophagy, and Parkinson's disease
    • Gusdon, A. M. and Chu, C. T. (2010). To eat or not to eat: neuronal metabolism, mitophagy, and Parkinson's disease. Antioxid. Redox Signal. 14, 1979-1987.
    • (2010) Antioxid. Redox Signal. , vol.14 , pp. 1979-1987
    • Gusdon, A.M.1    Chu, C.T.2
  • 34
    • 0036323447 scopus 로고    scopus 로고
    • MAP2 is required for dendrite elongation, PKA anchoring in dendrites, and proper PKA signal transduction
    • Harada, A., Teng, J., Takei, Y., Oguchi, K., and Hirokawa, N. (2002). MAP2 is required for dendrite elongation, PKA anchoring in dendrites, and proper PKA signal transduction. J. Cell. Biol. 158, 541-549.
    • (2002) J. Cell. Biol. , vol.158 , pp. 541-549
    • Harada, A.1    Teng, J.2    Takei, Y.3    Oguchi, K.4    Hirokawa, N.5
  • 36
    • 0030881687 scopus 로고    scopus 로고
    • D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain
    • Huang, L. J., Durick, K., Weiner, J. A., Chun, J., and Taylor, S. S. (1997). D-AKAP2, a novel protein kinase A anchoring protein with a putative RGS domain. Proc. Natl. Acad. Sci. USA 94, 11184-11189.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 11184-11189
    • Huang, L.J.1    Durick, K.2    Weiner, J.A.3    Chun, J.4    Taylor, S.S.5
  • 37
    • 84902658671 scopus 로고    scopus 로고
    • The neuroprotective effect of human uncoupling protein 2 (hUCP2) requires cAMP-dependent protein kinase in a toxin model of Parkinson's disease
    • Hwang, R. D., Wiemerslage, L., LaBreck, C. J., Khan, M., Kannan, K., Wang, X., Zhu, X., Lee, D., and Fridell, Y. W. (2014). The neuroprotective effect of human uncoupling protein 2 (hUCP2) requires cAMP-dependent protein kinase in a toxin model of Parkinson's disease. Neurobiol. Dis. 69, 180-191.
    • (2014) Neurobiol. Dis. , vol.69 , pp. 180-191
    • Hwang, R.D.1    Wiemerslage, L.2    Labreck, C.J.3    Khan, M.4    Kannan, K.5    Wang, X.6    Zhu, X.7    Lee, D.8    Fridell, Y.W.9
  • 40
    • 0029811871 scopus 로고    scopus 로고
    • Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade
    • Kim, Y. T. and Wu, C. F. (1996). Reduced growth cone motility in cultured neurons from Drosophila memory mutants with a defective cAMP cascade. J. Neurosci. 16, 5593-5602.
    • (1996) J. Neurosci. , vol.16 , pp. 5593-5602
    • Kim, Y.T.1    Wu, C.F.2
  • 42
    • 10944269186 scopus 로고    scopus 로고
    • The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
    • Li, Z., Okamoto, K., Hayashi, Y., and Sheng, M. (2004). The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119, 873-887.
    • (2004) Cell , vol.119 , pp. 873-887
    • Li, Z.1    Okamoto, K.2    Hayashi, Y.3    Sheng, M.4
  • 43
    • 84874713556 scopus 로고    scopus 로고
    • Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease
    • Lin, J. T., Chang, W. C., Chen, H. M., Lai, H. L., Chen, C. Y., Tao, M. H., and Chern, Y. (2013). Regulation of feedback between protein kinase A and the proteasome system worsens Huntington's disease. Mol. Cell. Biol. 33, 1073-1084.
    • (2013) Mol. Cell. Biol. , vol.33 , pp. 1073-1084
    • Lin, J.T.1    Chang, W.C.2    Chen, H.M.3    Lai, H.L.4    Chen, C.Y.5    Tao, M.H.6    Chern, Y.7
  • 45
    • 0026683504 scopus 로고
    • Dibutyryl cyclic AMP has epileptogenic potential in the hippocampus of freely behaving rats: A combined EEG-intracerebral microdialysis study
    • Ludvig, N., Mishra, P. K., and Jobe, P. C. (1992). Dibutyryl cyclic AMP has epileptogenic potential in the hippocampus of freely behaving rats: a combined EEG-intracerebral microdialysis study. Neurosci. Lett. 141, 187-191.
    • (1992) Neurosci. Lett. , vol.141 , pp. 187-191
    • Ludvig, N.1    Mishra, P.K.2    Jobe, P.C.3
  • 46
    • 33646261868 scopus 로고    scopus 로고
    • Nobiletin restoring â-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats
    • Matsuzaki, K., Yamakuni, T., Hashimoto, M., Haque, A. M., Shido, O., Mimaki, Y., Sashida, Y., and Ohizumi, Y. (2006). Nobiletin restoring â-amyloid-impaired CREB phosphorylation rescues memory deterioration in Alzheimer's disease model rats. Neurosci. Lett. 400, 230-234.
    • (2006) Neurosci. Lett. , vol.400 , pp. 230-234
    • Matsuzaki, K.1    Yamakuni, T.2    Hashimoto, M.3    Haque, A.M.4    Shido, O.5    Mimaki, Y.6    Sashida, Y.7    Ohizumi, Y.8
  • 49
    • 84872782873 scopus 로고    scopus 로고
    • N-terminal phosphorylation of protein phosphatase 2A/Bâ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival
    • Merrill, R. A., Slupe, A. M., and Strack, S. (2013). N-terminal phosphorylation of protein phosphatase 2A/Bâ2 regulates translocation to mitochondria, dynamin-related protein 1 dephosphorylation, and neuronal survival. FEBS J. 280, 662-673.
    • (2013) FEBS J. , vol.280 , pp. 662-673
    • Merrill, R.A.1    Slupe, A.M.2    Strack, S.3
  • 51
    • 30944449043 scopus 로고    scopus 로고
    • Mitochondrial modulation: Reversible phosphorylation takes center stage
    • Pagliarini, D. J. and Dixon, J. E. (2006). Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem. Sci. 31, 26-34.
    • (2006) Trends Biochem. Sci. , vol.31 , pp. 26-34
    • Pagliarini, D.J.1    Dixon, J.E.2
  • 52
    • 0037056042 scopus 로고    scopus 로고
    • The NDUFS4 nuclear gene of complex i of mitochondria and the cAMP cascade
    • Papa, S. (2002). The NDUFS4 nuclear gene of complex I of mitochondria and the cAMP cascade. Biochim. Biophys. Acta 1555, 147-153.
    • (2002) Biochim. Biophys. Acta , vol.1555 , pp. 147-153
    • Papa, S.1
  • 55
    • 39549117093 scopus 로고    scopus 로고
    • Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
    • Plowey, E. D., Cherra, S. J., 3rd, Liu, Y. J., and Chu, C. T. (2008). Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J. Neurochem. 105, 1048-1056.
    • (2008) J. Neurochem. , vol.105 , pp. 1048-1056
    • Plowey, E.D.1    Cherra, S.J.2    Liu, Y.J.3    Chu, C.T.4
  • 57
    • 80051791713 scopus 로고    scopus 로고
    • Downregulation of CREB expression in Alzheimer's brain and in Aâ-treated rat hippocampal neurons
    • Pugazhenthi, S., Wang, M., Pham, S., Sze, C. I., and Eckman, C. B. (2011). Downregulation of CREB expression in Alzheimer's brain and in Aâ-treated rat hippocampal neurons. Mol. Neurodegener. 6, 60.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 60
    • Pugazhenthi, S.1    Wang, M.2    Pham, S.3    Sze, C.I.4    Eckman, C.B.5
  • 60
    • 26244436267 scopus 로고    scopus 로고
    • CAMP regulates axon outgrowth and guidance during optic nerve regeneration in goldfish
    • Rodger, J., Goto, H., Cui, Q., Chen, P. B., and Harvey, A. R. (2005). cAMP regulates axon outgrowth and guidance during optic nerve regeneration in goldfish. Mol. Cell. Neurosci. 30, 452-464.
    • (2005) Mol. Cell. Neurosci. , vol.30 , pp. 452-464
    • Rodger, J.1    Goto, H.2    Cui, Q.3    Chen, P.B.4    Harvey, A.R.5
  • 61
    • 33749854516 scopus 로고    scopus 로고
    • Acute impairment of mitochondrial trafficking by â-amyloid peptides in hippocampal neurons
    • Rui, Y., Tiwari, P., Xie, Z., and Zheng, J. Q. (2006). Acute impairment of mitochondrial trafficking by â-amyloid peptides in hippocampal neurons. J. Neurosci. 26, 10480-10487.
    • (2006) J. Neurosci. , vol.26 , pp. 10480-10487
    • Rui, Y.1    Tiwari, P.2    Xie, Z.3    Zheng, J.Q.4
  • 62
    • 0001477595 scopus 로고
    • CAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
    • Rydel, R. E. and Greene, L. A. (1988). cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor. Proc. Natl. Acad. Sci. USA 85, 1257-1261.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 1257-1261
    • Rydel, R.E.1    Greene, L.A.2
  • 63
    • 84864516445 scopus 로고    scopus 로고
    • Metal protein attenuating compounds for the treatment of Alzheimer's dementia
    • Sampson, E. L., Jenagaratnam, L., and McShane, R. (2012). Metal protein attenuating compounds for the treatment of Alzheimer's dementia. Cochrane Database Syst. Rev. 5, CD005380.
    • (2012) Cochrane Database Syst. Rev. , vol.5 , pp. CD005380
    • Sampson, E.L.1    Jenagaratnam, L.2    McShane, R.3
  • 65
    • 84871325625 scopus 로고    scopus 로고
    • Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways
    • Sarina, Yagi, Y., Nakano, O., Hashimoto, T., Kimura, K., Asakawa, Y., Zhong, M., Narimatsu, S., and Gohda, E. (2013). Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways. Brain Res. 1490, 61-71.
    • (2013) Brain Res. , vol.1490 , pp. 61-71
    • Sarina Yagi, Y.1    Nakano, O.2    Hashimoto, T.3    Kimura, K.4    Asakawa, Y.5    Zhong, M.6    Narimatsu, S.7    Gohda, E.8
  • 68
    • 84855687153 scopus 로고    scopus 로고
    • Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
    • Sheng, B., Wang, X., Su, B., Lee, H. G., Casadesus, G., Perry, G., and Zhu, X. (2012). Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J. Neurochem. 120, 419-429.
    • (2012) J. Neurochem. , vol.120 , pp. 419-429
    • Sheng, B.1    Wang, X.2    Su, B.3    Lee, H.G.4    Casadesus, G.5    Perry, G.6    Zhu, X.7
  • 69
    • 77955792985 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease
    • and Protect Study, G.
    • Snow, B. J., Rolfe, F. L., Lockhart, M. M., Frampton, C. M., O'Sullivan, J. D., Fung, V., Smith, R. A., Murphy, M. P., Taylor, K. M., and Protect Study, G. (2010). A double-blind, placebo-controlled study to assess the mitochondria-targeted antioxidant MitoQ as a disease-modifying therapy in Parkinson's disease. Mov. Disord. 25, 1670-1674.
    • (2010) Mov. Disord. , vol.25 , pp. 1670-1674
    • Snow, B.J.1    Rolfe, F.L.2    Lockhart, M.M.3    Frampton, C.M.4    O'Sullivan, J.D.5    Fung, V.6    Smith, R.A.7    Murphy, M.P.8    Taylor, K.M.9
  • 70
    • 0036830613 scopus 로고    scopus 로고
    • Overexpression of the protein phosphatase 2A regulatory subunit B-promotes neuronal differentiation by activating the MAP kinase (MAPK) cascade
    • Strack, S. (2002). Overexpression of the protein phosphatase 2A regulatory subunit B-promotes neuronal differentiation by activating the MAP kinase (MAPK) cascade. J. Biol. Chem. 277, 41525-41532.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41525-41532
    • Strack, S.1
  • 71
    • 0036889681 scopus 로고    scopus 로고
    • Repetitive activation of protein kinase A induces slow and persistent potentiation associated with synaptogenesis in cultured hippocampus
    • Tominaga-Yoshino, K., Kondo, S., Tamotsu, S., and Ogura, A. (2002). Repetitive activation of protein kinase A induces slow and persistent potentiation associated with synaptogenesis in cultured hippocampus. Neurosci. Res. 44, 357-367.
    • (2002) Neurosci. Res. , vol.44 , pp. 357-367
    • Tominaga-Yoshino, K.1    Kondo, S.2    Tamotsu, S.3    Ogura, A.4
  • 72
    • 0035907325 scopus 로고    scopus 로고
    • Betaamyloid-( 1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival is not compromised
    • Tong, L., Thornton, P. L., Balazs, R., and Cotman, C. W. (2001). Betaamyloid-( 1-42) impairs activity-dependent cAMP-response element-binding protein signaling in neurons at concentrations in which cell survival Is not compromised. J. Biol. Chem. 276, 17301-17306.
    • (2001) J. Biol. Chem. , vol.276 , pp. 17301-17306
    • Tong, L.1    Thornton, P.L.2    Balazs, R.3    Cotman, C.W.4
  • 73
    • 3342908640 scopus 로고    scopus 로고
    • Betaamyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons
    • Tong, L., Balazs, R., Thornton, P. L., and Cotman, C. W. (2004). Betaamyloid peptide at sublethal concentrations downregulates brain-derived neurotrophic factor functions in cultured cortical neurons. J. Neurosci. 24, 6799-6809.
    • (2004) J. Neurosci. , vol.24 , pp. 6799-6809
    • Tong, L.1    Balazs, R.2    Thornton, P.L.3    Cotman, C.W.4
  • 74
    • 48149083835 scopus 로고    scopus 로고
    • Translational regulation of lipoprotein lipase in adipocytes: Depletion of cellular protein kinase C-activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA
    • Unal, R., Pokrovskaya, I., Tripathi, P., Monia, B. P., Kern, P. A., and Ranganathan, G. (2008). Translational regulation of lipoprotein lipase in adipocytes: depletion of cellular protein kinase C-activates binding of the C subunit of protein kinase A to the 3'-untranslated region of the lipoprotein lipase mRNA. Biochem. J. 413, 315-322.
    • (2008) Biochem. J. , vol.413 , pp. 315-322
    • Unal, R.1    Pokrovskaya, I.2    Tripathi, P.3    Monia, B.P.4    Kern, P.A.5    Ranganathan, G.6
  • 76
    • 23044506102 scopus 로고    scopus 로고
    • Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions
    • Verstreken, P., Ly, C. V., Venken, K. J., Koh, T. W., Zhou, Y., and Bellen, H. J. (2005). Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron 47, 365-378.
    • (2005) Neuron , vol.47 , pp. 365-378
    • Verstreken, P.1    Ly, C.V.2    Venken, K.J.3    Koh, T.W.4    Zhou, Y.5    Bellen, H.J.6
  • 77
    • 0036792096 scopus 로고    scopus 로고
    • Amyloid-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling
    • Vitolo, O. V., Sant'Angelo, A., Costanzo, V., Battaglia, F., Arancio, O., and Shelanski, M. (2002). Amyloid-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proc. Natl. Acad. Sci. USA 99, 13217-13221.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13217-13221
    • Vitolo, O.V.1    Sant'Angelo, A.2    Costanzo, V.3    Battaglia, F.4    Arancio, O.5    Shelanski, M.6
  • 79
    • 69249202594 scopus 로고    scopus 로고
    • Inhibition of LTP by-amyloid is prevented by activation of 2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway
    • Wang, Q. W., Rowan, M. J., and Anwyl, R. (2009). Inhibition of LTP by-amyloid is prevented by activation of 2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway. Neurobiol. Aging 30, 1608-1613.
    • (2009) Neurobiol. Aging , vol.30 , pp. 1608-1613
    • Wang, Q.W.1    Rowan, M.J.2    Anwyl, R.3
  • 81
    • 80052423497 scopus 로고    scopus 로고
    • Amyloid beta peptide-(1-42) induces internalization and degradation of 2 adrenergic receptors in prefrontal cortical neurons
    • Wang, D., Yuen, E. Y., Zhou, Y., Yan, Z., and Xiang, Y. K. (2011b). Amyloid beta peptide-(1-42) induces internalization and degradation of 2 adrenergic receptors in prefrontal cortical neurons. J. Biol. Chem. 286, 31852-31863.
    • (2011) J. Biol. Chem. , vol.286 , pp. 31852-31863
    • Wang, D.1    Yuen, E.Y.2    Zhou, Y.3    Yan, Z.4    Xiang, Y.K.5
  • 82
    • 84856607960 scopus 로고    scopus 로고
    • Influence of cAMP and protein kinase A on neurite length from spiral ganglion neurons
    • Xu, N., Engbers, J., Khaja, S., Xu, L., Clark, J. J., and Hansen, M. R. (2012). Influence of cAMP and protein kinase A on neurite length from spiral ganglion neurons. Hear. Res. 283, 33-44.
    • (2012) Hear. Res. , vol.283 , pp. 33-44
    • Xu, N.1    Engbers, J.2    Khaja, S.3    Xu, L.4    Clark, J.J.5    Hansen, M.R.6
  • 84
    • 42749091748 scopus 로고    scopus 로고
    • Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV
    • Yang, L., Calingasan, N. Y., Lorenzo, B. J., and Beal, M. F. (2008). Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV. Exp. Neurol. 211, 311-314.
    • (2008) Exp. Neurol. , vol.211 , pp. 311-314
    • Yang, L.1    Calingasan, N.Y.2    Lorenzo, B.J.3    Beal, M.F.4
  • 85
    • 0034668908 scopus 로고    scopus 로고
    • Two independent pathways mediated by cAMP and protein kinase A enhance spontaneous transmitter release at Drosophila neuromuscular junctions
    • Yoshihara, M., Suzuki, K., and Kidokoro, Y. (2000). Two independent pathways mediated by cAMP and protein kinase A enhance spontaneous transmitter release at Drosophila neuromuscular junctions. J. Neurosci. 20, 8315-8322.
    • (2000) J. Neurosci. , vol.20 , pp. 8315-8322
    • Yoshihara, M.1    Suzuki, K.2    Kidokoro, Y.3


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