Proteolysis of AKAP121 regulates mitochondrial activity during cellular hypoxia and brain ischaemia

EMBO Journal

Volumn 27, Issue 7, 2008, Pages 1073-1084

  Carlucci, Annalisa ^a   Adornetto, Annagrazia ^a   Scorziello, Antonella ^a   Viggiano, Davide ^a   Foca, Mariapaola ^a   Cuomo, Ornella ^a   Annunziato, Lucio ^a   Gottesman, Max ^b   Feliciello, Antonio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

AKAP; Hypoxia; Mitochondria; Siah2; Ubiquitin

Indexed keywords

A KINASE ANCHOR PROTEIN 121; CYCLIC AMP; GLUCOSE; MITOCHONDRIAL PROTEIN; OXYGEN; SIAH2 ENZYME; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; CELL SURVIVAL; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; MALE; MIDDLE CEREBRAL ARTERY; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION; UBIQUITINATION;

A KINASE ANCHOR PROTEINS; ANIMALS; BRAIN ISCHEMIA; CELL HYPOXIA; GLUCOSE; HUMANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MIDDLE CEREBRAL ARTERY; MITOCHONDRIA; MODELS, BIOLOGICAL; NIH 3T3 CELLS; NUCLEAR PROTEINS; OXYGEN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 41949084995     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2008.33     Document Type: Article

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