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Volumn 36, Issue 5, 2015, Pages 3429-3439

Reactive oxygen species, glutathione, and thioredoxin influence suberoyl bishydroxamic acid-induced apoptosis in A549 lung cancer cells

Author keywords

Apoptosis; Glutathione; Reactive oxygen species; Suberoyl bishydroxamic acid; Thioredoxin

Indexed keywords

ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; ANTIOXIDANT; GLUTATHIONE; HISTONE DEACETYLASE INHIBITOR; REACTIVE OXYGEN METABOLITE; SUBEROYL BISHYDROXAMIC ACID; THIOREDOXIN; THIOREDOXIN 1; UNCLASSIFIED DRUG; HYDROXAMIC ACID; SUBEROYL BIS-HYDROXAMIC ACID;

EID: 84929945980     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-014-2978-6     Document Type: Article
Times cited : (27)

References (41)
  • 1
    • 84857559399 scopus 로고    scopus 로고
    • Histone modification at the gene level
    • COI: 1:CAS:528:DC%2BC38Xislygtrk%3D, PID: 22362212
    • Burgess DJ. Histone modification at the gene level. Nat Rev Cancer. 2012;12:156.
    • (2012) Nat Rev Cancer , vol.12 , pp. 156
    • Burgess, D.J.1
  • 2
    • 74849127193 scopus 로고    scopus 로고
    • Epigenetic therapy: histone acetylation, DNA methylation and anti-cancer drug discovery
    • COI: 1:CAS:528:DC%2BC3cXhslKnsLc%3D, PID: 20025605
    • Ganesan A, Nolan L, Crabb SJ, Packham G. Epigenetic therapy: histone acetylation, DNA methylation and anti-cancer drug discovery. Curr Cancer Drug Targets. 2009;9:963–81.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 963-981
    • Ganesan, A.1    Nolan, L.2    Crabb, S.J.3    Packham, G.4
  • 3
    • 38549151212 scopus 로고    scopus 로고
    • Overexpression of hdacs: a prognostic marker for gastric cancer identified by tissue microarray
    • PID: 18237848
    • Kanai Y. Overexpression of hdacs: a prognostic marker for gastric cancer identified by tissue microarray. Lancet Oncol. 2008;9:91–3.
    • (2008) Lancet Oncol , vol.9 , pp. 91-93
    • Kanai, Y.1
  • 4
    • 77953442499 scopus 로고    scopus 로고
    • Increased expression of histone deacetylaces (hdacs) and inhibition of prostate cancer growth and invasion by hdac inhibitor saha
    • COI: 1:CAS:528:DC%2BD1MXhtFejs7jI, PID: 19966939
    • Wang L, Zou X, Berger AD, Twiss C, Peng Y, Li Y, et al. Increased expression of histone deacetylaces (hdacs) and inhibition of prostate cancer growth and invasion by hdac inhibitor saha. Am J Transl Res. 2009;1:62–71.
    • (2009) Am J Transl Res , vol.1 , pp. 62-71
    • Wang, L.1    Zou, X.2    Berger, A.D.3    Twiss, C.4    Peng, Y.5    Li, Y.6
  • 5
    • 71049115609 scopus 로고    scopus 로고
    • High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo
    • PID: 19912635
    • Lehmann A, Denkert C, Budczies J, Buckendahl AC, Darb-Esfahani S, Noske A, et al. High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo. BMC Cancer. 2009;9:395.
    • (2009) BMC Cancer , vol.9 , pp. 395
    • Lehmann, A.1    Denkert, C.2    Budczies, J.3    Buckendahl, A.C.4    Darb-Esfahani, S.5    Noske, A.6
  • 6
    • 84856524861 scopus 로고    scopus 로고
    • Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy
    • COI: 1:CAS:528:DC%2BC3MXotlCmt7g%3D, PID: 21725353
    • Spiegel S, Milstien S, Grant S. Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Oncogene. 2012;31:537–51.
    • (2012) Oncogene , vol.31 , pp. 537-551
    • Spiegel, S.1    Milstien, S.2    Grant, S.3
  • 7
    • 73949128107 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors in cancer therapy
    • COI: 1:CAS:528:DC%2BD1MXhsFKkt7vE
    • Lane AA, Chabner BA. Histone deacetylase inhibitors in cancer therapy. J Clin Oncol Off J Am Soc Clin Oncol. 2009;27:5459–68.
    • (2009) J Clin Oncol Off J Am Soc Clin Oncol , vol.27 , pp. 5459-5468
    • Lane, A.A.1    Chabner, B.A.2
  • 8
    • 84860186290 scopus 로고    scopus 로고
    • Cs055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells
    • COI: 1:CAS:528:DC%2BC38Xls1Shtrw%3D, PID: 22339555
    • Gong K, Xie J, Yi H, Li W. Cs055 (Chidamide/HBI-8000), a novel histone deacetylase inhibitor, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells. Biochem J. 2012;443:735–46.
    • (2012) Biochem J , vol.443 , pp. 735-746
    • Gong, K.1    Xie, J.2    Yi, H.3    Li, W.4
  • 9
    • 84873625043 scopus 로고    scopus 로고
    • Trichostatin A induces apoptotic cell death of HeLa cells in a Bcl-2 and oxidative stress-dependent manner
    • PID: 23165748
    • You BR, Park WH. Trichostatin A induces apoptotic cell death of HeLa cells in a Bcl-2 and oxidative stress-dependent manner. Int J Oncol. 2012;42:359–66.
    • (2012) Int J Oncol , vol.42 , pp. 359-366
    • You, B.R.1    Park, W.H.2
  • 10
    • 0038079767 scopus 로고    scopus 로고
    • The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1
    • COI: 1:CAS:528:DC%2BD3sXltVGrurc%3D, PID: 12839953
    • Rosato RR, Almenara JA, Grant S. The histone deacetylase inhibitor MS-275 promotes differentiation or apoptosis in human leukemia cells through a process regulated by generation of reactive oxygen species and induction of p21CIP1/WAF1 1. Cancer Res. 2003;63:3637–45.
    • (2003) Cancer Res , vol.63 , pp. 3637-3645
    • Rosato, R.R.1    Almenara, J.A.2    Grant, S.3
  • 11
    • 33645869877 scopus 로고    scopus 로고
    • Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells
    • COI: 1:CAS:528:DC%2BD28XktFamtLY%3D, PID: 16497787
    • Martirosyan A, Leonard S, Shi X, Griffith B, Gannett P, Strobl J. Actions of a histone deacetylase inhibitor NSC3852 (5-nitroso-8-quinolinol) link reactive oxygen species to cell differentiation and apoptosis in MCF-7 human mammary tumor cells. J Pharmacol Exp Ther. 2006;317:546–52.
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 546-552
    • Martirosyan, A.1    Leonard, S.2    Shi, X.3    Griffith, B.4    Gannett, P.5    Strobl, J.6
  • 12
    • 1642286961 scopus 로고    scopus 로고
    • The role of ROS and RNS in regulating life and death of blood monocytes
    • COI: 1:CAS:528:DC%2BD2cXisVaiu70%3D, PID: 15032689
    • Baran CP, Zeigler MM, Tridandapani S, Marsh CB. The role of ROS and RNS in regulating life and death of blood monocytes. Curr Pharm Des. 2004;10:855–66.
    • (2004) Curr Pharm Des , vol.10 , pp. 855-866
    • Baran, C.P.1    Zeigler, M.M.2    Tridandapani, S.3    Marsh, C.B.4
  • 13
    • 2342420427 scopus 로고    scopus 로고
    • Oxygen, reactive oxygen species and tissue damage
    • COI: 1:CAS:528:DC%2BD2cXjsVyktbk%3D, PID: 15134560
    • Bergamini CM, Gambetti S, Dondi A, Cervellati C. Oxygen, reactive oxygen species and tissue damage. Curr Pharm Des. 2004;10:1611–26.
    • (2004) Curr Pharm Des , vol.10 , pp. 1611-1626
    • Bergamini, C.M.1    Gambetti, S.2    Dondi, A.3    Cervellati, C.4
  • 14
    • 80053111570 scopus 로고    scopus 로고
    • Antioxidant potential of glutathione: a theoretical study
    • COI: 1:CAS:528:DC%2BC3MXhtFelurfP, PID: 21853966
    • Fiser B, Szori M, Jojart B, Izsak R, Csizmadia IG, Viskolcz B. Antioxidant potential of glutathione: a theoretical study. J Phys Chem B. 2011;115:11269–77.
    • (2011) J Phys Chem B , vol.115 , pp. 11269-11277
    • Fiser, B.1    Szori, M.2    Jojart, B.3    Izsak, R.4    Csizmadia, I.G.5    Viskolcz, B.6
  • 15
    • 0033567420 scopus 로고    scopus 로고
    • Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (l-phenylalanine mustard) in human colorectal cancer cells
    • COI: 1:CAS:528:DyaK1MXks1WrsLY%3D, PID: 10413303
    • Vahrmeijer AL, van Dierendonck JH, Schutrups J, van de Velde CJ, Mulder GJ. Effect of glutathione depletion on inhibition of cell cycle progression and induction of apoptosis by melphalan (l-phenylalanine mustard) in human colorectal cancer cells. Biochem Pharmacol. 1999;58:655–64.
    • (1999) Biochem Pharmacol , vol.58 , pp. 655-664
    • Vahrmeijer, A.L.1    van Dierendonck, J.H.2    Schutrups, J.3    van de Velde, C.J.4    Mulder, G.J.5
  • 16
    • 34250187433 scopus 로고    scopus 로고
    • Glutathione and glutathione-linked enzymes in normal human aortic smooth muscle cells: chemical inducibility and protection against reactive oxygen and nitrogen species-induced injury
    • COI: 1:CAS:528:DC%2BD2sXmtFegu74%3D, PID: 17206382
    • Zhu H, Cao Z, Zhang L, Trush MA, Li Y. Glutathione and glutathione-linked enzymes in normal human aortic smooth muscle cells: chemical inducibility and protection against reactive oxygen and nitrogen species-induced injury. Mol Cell Biochem. 2007;301:47–59.
    • (2007) Mol Cell Biochem , vol.301 , pp. 47-59
    • Zhu, H.1    Cao, Z.2    Zhang, L.3    Trush, M.A.4    Li, Y.5
  • 17
    • 0026637964 scopus 로고
    • Role of cellular superoxide dismutase against reactive oxygen metabolite injury in cultured bovine aortic endothelial cells
    • COI: 1:CAS:528:DyaK38XlsVygt70%3D, PID: 1321816
    • Hiraishi H, Terano A, Razandi M, Sugimoto T, Harada T, Ivey KJ. Role of cellular superoxide dismutase against reactive oxygen metabolite injury in cultured bovine aortic endothelial cells. J Biol Chem. 1992;267:14812–7.
    • (1992) J Biol Chem , vol.267 , pp. 14812-14817
    • Hiraishi, H.1    Terano, A.2    Razandi, M.3    Sugimoto, T.4    Harada, T.5    Ivey, K.J.6
  • 18
    • 79952744551 scopus 로고    scopus 로고
    • Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis
    • COI: 1:CAS:528:DC%2BC3MXltFGjt7c%3D, PID: 21244577
    • Yang L, Zheng XL, Sun H, Zhong YJ, Wang Q, He HN, et al. Catalase suppression-mediated H(2)O(2) accumulation in cancer cells by wogonin effectively blocks tumor necrosis factor-induced NF-κB activation and sensitizes apoptosis. Cancer Sci. 2011;102:870–6.
    • (2011) Cancer Sci , vol.102 , pp. 870-876
    • Yang, L.1    Zheng, X.L.2    Sun, H.3    Zhong, Y.J.4    Wang, Q.5    He, H.N.6
  • 19
    • 33751178410 scopus 로고    scopus 로고
    • The thioredoxin system in cancer
    • COI: 1:CAS:528:DC%2BD28Xht1eqt7%2FP, PID: 17092741
    • Arner ES, Holmgren A. The thioredoxin system in cancer. Semin Cancer Biol. 2006;16:420–6.
    • (2006) Semin Cancer Biol , vol.16 , pp. 420-426
    • Arner, E.S.1    Holmgren, A.2
  • 20
    • 77956312086 scopus 로고    scopus 로고
    • Structure, function, and mechanism of thioredoxin proteins
    • COI: 1:CAS:528:DC%2BC3cXhtFSisrvN, PID: 20136512
    • Collet JF, Messens J. Structure, function, and mechanism of thioredoxin proteins. Antioxid Redox Signal. 2010;13:1205–16.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1205-1216
    • Collet, J.F.1    Messens, J.2
  • 21
    • 38149090141 scopus 로고    scopus 로고
    • Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer
    • COI: 1:CAS:528:DC%2BD1cXovFKqtw%3D%3D, PID: 17949784
    • Noike T, Miwa S, Soeda J, Kobayashi A, Miyagawa S. Increased expression of thioredoxin-1, vascular endothelial growth factor, and redox factor-1 is associated with poor prognosis in patients with liver metastasis from colorectal cancer. Hum Pathol. 2008;39:201–8.
    • (2008) Hum Pathol , vol.39 , pp. 201-208
    • Noike, T.1    Miwa, S.2    Soeda, J.3    Kobayashi, A.4    Miyagawa, S.5
  • 22
    • 84857997426 scopus 로고    scopus 로고
    • Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells
    • COI: 1:CAS:528:DC%2BC38Xjt1OqtL0%3D, PID: 22342720
    • Karlenius TC, Shah F, Di Trapani G, Clarke FM, Tonissen KF. Cycling hypoxia up-regulates thioredoxin levels in human MDA-MB-231 breast cancer cells. Biochem Biophys Res Commun. 2012;419:350–5.
    • (2012) Biochem Biophys Res Commun , vol.419 , pp. 350-355
    • Karlenius, T.C.1    Shah, F.2    Di Trapani, G.3    Clarke, F.M.4    Tonissen, K.F.5
  • 23
    • 69549116697 scopus 로고    scopus 로고
    • Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation
    • PID: 19723146
    • Fernandes AP, Capitanio A, Selenius M, Brodin O, Rundlof AK, Bjornstedt M. Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation. Histopathology. 2009;55:313–20.
    • (2009) Histopathology , vol.55 , pp. 313-320
    • Fernandes, A.P.1    Capitanio, A.2    Selenius, M.3    Brodin, O.4    Rundlof, A.K.5    Bjornstedt, M.6
  • 25
    • 78449297433 scopus 로고    scopus 로고
    • Suberoyl bishydroxamic acid inhibits the growth of A549 lung cancer cells via caspase-dependent apoptosis
    • COI: 1:CAS:528:DC%2BC3cXht1KqsLjF, PID: 20652372
    • You BR, Park WH. Suberoyl bishydroxamic acid inhibits the growth of A549 lung cancer cells via caspase-dependent apoptosis. Mol Cell Biochem. 2010;344:203–10.
    • (2010) Mol Cell Biochem , vol.344 , pp. 203-210
    • You, B.R.1    Park, W.H.2
  • 26
    • 84878410730 scopus 로고    scopus 로고
    • Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner
    • COI: 1:CAS:528:DC%2BC3sXkslagtLg%3D, PID: 23269626
    • You BR, Park WH. Suberoyl bishydroxamic acid-induced apoptosis in HeLa cells via ROS-independent, GSH-dependent manner. Mol Biol Rep. 2013;40:3807–16.
    • (2013) Mol Biol Rep. , vol.40 , pp. 3807-3816
    • You, B.R.1    Park, W.H.2
  • 27
    • 68349109741 scopus 로고    scopus 로고
    • The effects of n-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione
    • COI: 1:CAS:528:DC%2BD1MXpt12qt7g%3D, PID: 19578781
    • Han YH, Park WH. The effects of n-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione. Oncol Rep. 2009;22:385–91.
    • (2009) Oncol Rep , vol.22 , pp. 385-391
    • Han, Y.H.1    Park, W.H.2
  • 28
    • 71749103032 scopus 로고    scopus 로고
    • Effects of carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone on the growth inhibition in human pulmonary adenocarcinoma Calu-6 cells
    • COI: 1:CAS:528:DC%2BD1MXhsVWlsrrP, PID: 19819288
    • Han YH, Moon HJ, You BR, Kim SZ, Kim SH, Park WH. Effects of carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone on the growth inhibition in human pulmonary adenocarcinoma Calu-6 cells. Toxicology. 2009;265:101–7.
    • (2009) Toxicology , vol.265 , pp. 101-107
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Kim, S.Z.4    Kim, S.H.5    Park, W.H.6
  • 29
    • 68249153842 scopus 로고    scopus 로고
    • The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH
    • COI: 1:CAS:528:DC%2BD1MXoslymsLc%3D, PID: 19513526
    • Han YH, Moon HJ, You BR, Park WH. The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH. Oncol Rep. 2009;22:215–21.
    • (2009) Oncol Rep , vol.22 , pp. 215-221
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Park, W.H.4
  • 30
    • 69549116458 scopus 로고    scopus 로고
    • Propyl gallate inhibits the growth of HeLa cells via regulating intracellular GSH level
    • COI: 1:CAS:528:DC%2BD1MXhtV2ltrfP
    • Han YH, Park WH. Propyl gallate inhibits the growth of HeLa cells via regulating intracellular GSH level. Food Chem Toxicol Int J Published Br Ind Biol Res Assoc. 2009;47:2531–8.
    • (2009) Food Chem Toxicol Int J Published Br Ind Biol Res Assoc , vol.47 , pp. 2531-2538
    • Han, Y.H.1    Park, W.H.2
  • 31
    • 84863445333 scopus 로고    scopus 로고
    • Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion
    • COI: 1:CAS:528:DC%2BC38Xht1ajt7bM, PID: 22684917
    • You BR, Park WH. Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion. Oncol Rep. 2012;28:749–57.
    • (2012) Oncol Rep , vol.28 , pp. 749-757
    • You, B.R.1    Park, W.H.2
  • 32
    • 84868525918 scopus 로고    scopus 로고
    • Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis
    • COI: 1:CAS:528:DC%2BC38Xht1ynsLnF, PID: 22718513
    • You BR, Park WH. Zebularine inhibits the growth of HeLa cervical cancer cells via cell cycle arrest and caspase-dependent apoptosis. Mol Biol Rep. 2012;39:9723–31.
    • (2012) Mol Biol Rep , vol.39 , pp. 9723-9731
    • You, B.R.1    Park, W.H.2
  • 33
    • 77952953361 scopus 로고    scopus 로고
    • Propyl gallate inhibits the growth of calf pulmonary arterial endothelial cells via glutathione depletion
    • COI: 1:CAS:528:DC%2BC3cXmtFersrw%3D
    • Han YH, Moon HJ, You BR, Park WH. Propyl gallate inhibits the growth of calf pulmonary arterial endothelial cells via glutathione depletion. Toxicol Vitro Int J Published Ass BIBRA. 2010;24:1183–9.
    • (2010) Toxicol Vitro Int J Published Ass BIBRA , vol.24 , pp. 1183-1189
    • Han, Y.H.1    Moon, H.J.2    You, B.R.3    Park, W.H.4
  • 34
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide rnas mediate rna interference in cultured mammalian cells
    • COI: 1:CAS:528:DC%2BD3MXkt1ejt7Y%3D, PID: 11373684
    • Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide rnas mediate rna interference in cultured mammalian cells. Nature. 2001;411:494–8.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 35
    • 58149131828 scopus 로고    scopus 로고
    • Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2 (*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells
    • PID: 18585819
    • Han YH, Kim SH, Kim SZ, Park WH. Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2 (*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells. Lung Cancer. 2009;63:201–9.
    • (2009) Lung Cancer , vol.63 , pp. 201-209
    • Han, Y.H.1    Kim, S.H.2    Kim, S.Z.3    Park, W.H.4
  • 36
    • 41849089734 scopus 로고    scopus 로고
    • Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death
    • COI: 1:CAS:528:DC%2BD1cXktFCksrs%3D, PID: 18157160
    • Tian C, Gao P, Zheng Y, Yue W, Wang X, Jin H, et al. Redox status of thioredoxin-1 (TRX1) determines the sensitivity of human liver carcinoma cells (HepG2) to arsenic trioxide-induced cell death. Cell Res. 2008;18:458–71.
    • (2008) Cell Res , vol.18 , pp. 458-471
    • Tian, C.1    Gao, P.2    Zheng, Y.3    Yue, W.4    Wang, X.5    Jin, H.6
  • 37
    • 84865690949 scopus 로고    scopus 로고
    • Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma
    • COI: 1:CAS:528:DC%2BC38XhtlWgs77L, PID: 22447839
    • Li C, Thompson MA, Tamayo AT, Zuo Z, Lee J, Vega F, et al. Over-expression of Thioredoxin-1 mediates growth, survival, and chemoresistance and is a druggable target in diffuse large B-cell lymphoma. Oncotarget. 2012;3:314–26.
    • (2012) Oncotarget , vol.3 , pp. 314-326
    • Li, C.1    Thompson, M.A.2    Tamayo, A.T.3    Zuo, Z.4    Lee, J.5    Vega, F.6
  • 38
    • 2042470971 scopus 로고    scopus 로고
    • Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene
    • COI: 1:CAS:528:DyaK28XlsV2isLY%3D, PID: 8812119
    • Matsui M, Oshima M, Oshima H, Takaku K, Maruyama T, Yodoi J, et al. Early embryonic lethality caused by targeted disruption of the mouse thioredoxin gene. Dev Biol. 1996;178:179–85.
    • (1996) Dev Biol , vol.178 , pp. 179-185
    • Matsui, M.1    Oshima, M.2    Oshima, H.3    Takaku, K.4    Maruyama, T.5    Yodoi, J.6
  • 39
    • 45149125713 scopus 로고    scopus 로고
    • Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide
    • COI: 1:CAS:528:DC%2BD1cXntlWgs7o%3D, PID: 18247324
    • Han YH, Kim SZ, Kim SH, Park WH. Intracellular GSH level is a factor in As4.1 juxtaglomerular cell death by arsenic trioxide. J Cell Biochem. 2008;104:995–1009.
    • (2008) J Cell Biochem , vol.104 , pp. 995-1009
    • Han, Y.H.1    Kim, S.Z.2    Kim, S.H.3    Park, W.H.4
  • 40
    • 0034306869 scopus 로고    scopus 로고
    • Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells
    • COI: 1:CAS:528:DC%2BD3cXntlSit70%3D, PID: 11013356
    • Schnelldorfer T, Gansauge S, Gansauge F, Schlosser S, Beger HG, Nussler AK. Glutathione depletion causes cell growth inhibition and enhanced apoptosis in pancreatic cancer cells. Cancer. 2000;89:1440–7.
    • (2000) Cancer , vol.89 , pp. 1440-1447
    • Schnelldorfer, T.1    Gansauge, S.2    Gansauge, F.3    Schlosser, S.4    Beger, H.G.5    Nussler, A.K.6
  • 41
    • 84855470386 scopus 로고    scopus 로고
    • Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione
    • COI: 1:CAS:528:DC%2BC38XltVGjsQ%3D%3D, PID: 21856323
    • Brechbuhl HM, Kachadourian R, Min E, Chan D, Day BJ. Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione. Toxicol Appl Pharmacol. 2012;258:1–9.
    • (2012) Toxicol Appl Pharmacol , vol.258
    • Brechbuhl, H.M.1    Kachadourian, R.2    Min, E.3    Chan, D.4    Day, B.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.