A G protein-coupled receptor dimer imaging assay reveals selectively modified pharmacology of neuropeptide y Y1/Y5 receptor heterodimers

Molecular Pharmacology

Volumn 87, Issue 4, 2015, Pages 718-732

  Kilpatrick, Laura E ^a   Humphrys, Laura J ^a   Holliday, Nicholas D ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOBESITY AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN; DIMER; G PROTEIN COUPLED RECEPTOR; HETERODIMER; HOMODIMER; MONOMER; N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NEUROPEPTIDE Y1 RECEPTOR; NEUROPEPTIDE Y5 RECEPTOR; NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y-Y1 RECEPTOR;

APPETITE; ARTICLE; AUTOMATION; BIMOLECULAR FLUORESCENCE COMPLEMENTATION; BINDING SITE; CLINICAL PHARMACOLOGY; DRUG EFFICACY; DRUG POTENCY; ENDOCYTOSIS; FLUORESCENCE; GENE MUTATION; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; AGONISTS; ALLOSTERISM; ANIMAL; ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; FLUORESCENCE IMAGING; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR IMAGING; MUTATION; PHOSPHORYLATION; PROMOTER REGION; PROTEIN MULTIMERIZATION; RADIOASSAY; RAT; SECOND MESSENGER;

ALLOSTERIC REGULATION; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; ENDOCYTOSIS; HEK293 CELLS; HUMANS; MOLECULAR IMAGING; MUTATION; OPTICAL IMAGING; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN MULTIMERIZATION; RADIOLIGAND ASSAY; RATS; RECEPTORS, NEUROPEPTIDE Y; SECOND MESSENGER SYSTEMS;

EID: 84929941384     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.114.095356     Document Type: Article

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