The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced β-arrestin 2 interaction

Journal of Pharmacology and Experimental Therapeutics

Volumn 306, Issue 1, 2003, Pages 147-156

  Berglund, Magnus M ^a   Schober, Douglas A ^a   Statnick, Michael A ^a   McDonald, Patricia H ^a   Gehlert, Donald R ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR Y1; G PROTEIN COUPLED RECEPTOR Y2; G PROTEIN COUPLED RECEPTOR Y4; G PROTEIN COUPLED RECEPTOR Y5; GR 231118; GREEN FLUORESCENT PROTEIN; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR AGONIST; PANCREAS POLYPEPTIDE; PEPTIDE YY; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ARTICLE; BIOLUMINESCENCE; DRUG EFFECT; ENERGY TRANSFER; HUMAN; HUMAN CELL; INTERNALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; RECEPTOR DOWN REGULATION;

AMINO ACID SEQUENCE; ANIMALS; ARRESTINS; CLONING, MOLECULAR; ENERGY TRANSFER; HUMANS; LUMINESCENT MEASUREMENTS; MACACA MULATTA; MOLECULAR SEQUENCE DATA; NEUROPEPTIDE Y; PANCREATIC POLYPEPTIDE; PEPTIDE YY; RECEPTORS, NEUROPEPTIDE Y; SEQUENCE HOMOLOGY, AMINO ACID; TIME FACTORS;

EID: 0038341013     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.051227     Document Type: Article

References (26)

1. Angers S, Salahpour A, and Bouvier M (2002) Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function. Annu Rev Pharmacol Toxicol 42:409-435.
2. Angers S, Salahpour A, Joly E, Hilairet S, Chelsky D, Dennis M, and Bouvier M (2000) Detection of β2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET). Proc Natl Acad Sci USA 97:3684-3689.
3. Berglund MM, Hipskind PA, and Gehlert DR (2003) Recent developments in our understanding of the physiological role of PP-fold peptide receptor subtypes. Exp Biol Med 228:217-244.
4. Boute N, Pernet K, and Issad T (2001) Monitoring the activation state of the insulin receptor using bioluminescence resonance energy transfer. Mol Pharmacol 60:640-645.
5. Criscione L, Rigollier P, Batzl-Hartmann C, Rueger H, Stricker-Krongrad A, Wyss P, Brunner L, Whitebread S, Yamaguchi Y, Gerald C, et al. (1998) Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor. J Clin Investig 102:2136-2145.
6. Daniels AJ, Matthews JE, Slepetis RJ, Jansen M, Viveros OH, Tadepalli A, Harrington W, Heyer D, Landavazo A, Leban JJ, et al. (1995) High-affinity neuropeptide Y receptor antagonists. Proc Natl Acad Sci USA 92:9067-9071.
7. DeGraff JL, Gurevich VV, and Benovic JL (2002) The third intracellular loop of α2-adrenergic receptors determines subtype specificity of arrestin interaction. J Biol Chem 277:43247-43252.
8. Doods H, Gaida W, Wieland HA, Dollinger H, Schnorrenberg G, Esser F, Engel W, Eberlein W, and Rudolf K (1999) BIIE0246: a selective and high affinity neuropeptide Y Y(2) receptor antagonist. Eur J Pharmacol 384:R3-R5.
9. Fabry M, Langer M, Rothen-Rutishauser B, Wunderli-Allenspach H, Hocker H, and Beck-Sickinger AG (2000) Monitoring of the internalization of neuropeptide Y on neuroblastoma cell line SK-N-MC. Eur J Biochem 267:5631-5637.
10. 125I-labeled peptide YY binding sites in the rat brain. Neurochem Int 21:45-67.
11. Gehlert DR, Yang P, George C, Wang Y, Schober D, Gackenheimer S, Johnson D, Beavers LS, Gadski RA, and Baez M (2001) Cloning and characterization of rhesus monkey neuropeptide Y receptor subtypes. Peptides 22:343-350.
12. Gicquiaux H, Lecat S, Gaire M, Dieterlen A, Mely Y, Takeda K, Bucher B, and Galzi JL (2002) Rapid internalization and recycling of the human neuropeptide Y Y1 receptor. J Biol Chem 277:6645-6655.
13. Hanyaloglu AC, Seeber RM, Kohout TA, Lefkowitz RJ, and Eidne KA (2002) Homo-and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor sub-types. Differential regulation of β-arrestins 1 and 2. J Biol Chem 277:50422-50430.
14. McDonald PH and Lefkowitz RJ (2001) β-Arrestins: new roles in regulating heptahelical receptors' functions. Cell Signal 13:683-689.
15. Oakley RH, Laporte SA, Holt JA, Barak LS, and Caron MG (2001) Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-β-arrestin complexes after receptor endocytosis. J Biol Chem 276:19452-19460.
16. Parker EM, Babij CK, Balasubramaniam A, Burrier RE, Guzzi M, Hamud F, Mukhopadhyay G, Rudinski MS, Tao Z, Tice M, et al. (1998) GR231118 (1229U91) and other analogues of the C-terminus of neuropeptide Y are potent neuropeptide Y Y1 receptor antagonists and neuropeptide Y Y4 receptor agonists. Eur J Pharmacol 349:97-105.
17. Parker SL, Kane JK, Parker MS, Berglund MM, Lundell IA, and Li MD (2001) Cloned neuropeptide Y (NPY) Y1 and pancreatic polypeptide Y4 receptors expressed in Chinese hamster ovary cells show considerable agonist-driven internalization, in contrast to the NPY Y2 receptor. Eur J Biochem 268:877-886.
18. Parker SL, Parker MS, Lundell I, Balasubramaniam A, Buschauer A, Kane JK, Yalcin A, and Berglund MM (2002) Agonist internalization by cloned Y1 neuropeptide Y (NPY) receptor in Chinese hamster ovary cells shows strong preference for NPY, endosome-linked entry and fast receptor recycling. Regul Pept 107:49-62.
19. Pierce KL and Lefkowitz RJ (2001) Classical and new roles of β arrestin in the regulation of G-protein-coupled receptors. Nat Rev 2:727-733.
20. Pronchuk N, Beck-Sickinger AG, and Colmers WF (2002) Multiple NPY receptors inhibit GABA(A) synaptic responses of rat medial parvocellular effector neurons in the hypothalamic paraventricular nucleus. Endocrinology 143:535-543.
21. Ramsay D, Kellett E, McVey M, Rees S, and Milligan G (2002) Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between less closely related sequences. Biochem J 365:429-440.
22. Rudolf K, Eberlein W, Engel W, Wieland HA, Willim KD, Entzeroth M, Wienen W, Beck-Sickinger AG, and Doods HN (1994) The first highly potent and selective non-peptide neuropeptide Y Y1 receptor antagonist: BIBP3226. Eur J Pharmacol 271:R11-R13.
23. Schober DA, Van Abbema AM, Smiley DL, Bruns RF, and Gehlert DR (1998) The neuropeptide Y Y1 antagonist, 1229U91, a potent agonist for the human pancreatic polypeptide-preferring (NPY Y4) receptor. Peptides 19:537-542.
24. Takei K and Haucke V (2001) Clathrin-mediated endocytosis: membrane factors pull the trigger. Trends Cell Biol 11:385-391.
25. Wade SM, Lim WK, Lan KL, Chung DA, Nanamori M, and Neubig RR (1999) G(i) activator region of α(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation. Mol Pharmacol 56:1005-1013.
26. Xu Y, Piston DW, and Johnson CH (1999) A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins. Proc Natl Acad Sci USA 96:151-156.