-
1
-
-
84905220599
-
-
Accessed May 23, 2013
-
WHO. Obesity and Overweight [Internet]; 2013.http://www.who.int/ mediacentre/factsheets/fs311/en/. Accessed May 23, 2013.
-
(2013)
Obesity and Overweight [Internet]
-
-
-
2
-
-
0032010796
-
Current estimates of the economic cost of obesity in the United States
-
Wolf AM, Colditz GA. Current estimates of the economic cost of obesity in the United States. Obes Res. 1998 ; 6 (2). 97-106
-
(1998)
Obes Res
, vol.6
, Issue.2
, pp. 97-106
-
-
Wolf, A.M.1
Colditz, G.A.2
-
3
-
-
49149109159
-
Population-based prevention of obesity: The need for comprehensive promotion of healthful eating, physical activity, and energy balance: A scientific statement from American heart association council on epidemiology and prevention, interdisciplinary committee for prevention (formerly the expert panel on population and prevention science)
-
Kumanyika SK, Obarzanek E, Stettler N, et al. Population-based prevention of obesity: the need for comprehensive promotion of healthful eating, physical activity, and energy balance: a scientific statement from American heart association council on epidemiology and prevention, interdisciplinary committee for prevention (formerly the expert panel on population and prevention science). Circulation. 2008 ; 118 (4). 428-464
-
(2008)
Circulation
, vol.118
, Issue.4
, pp. 428-464
-
-
Kumanyika, S.K.1
Obarzanek, E.2
Stettler, N.3
-
5
-
-
65549109680
-
Obesity and cardiovascular disease: Risk factor, paradox, and impact of weight loss
-
Lavie CJ, Milani RV, Ventura HO. Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J Am Coll Cardiol. 2009 ; 53 (21). 1925-1932
-
(2009)
J Am Coll Cardiol
, vol.53
, Issue.21
, pp. 1925-1932
-
-
Lavie, C.J.1
Milani, R.V.2
Ventura, H.O.3
-
6
-
-
77951101449
-
Systematic prevention of overweight and obesity in adults: A qualitative and quantitative literature analysis
-
Kremers S, Reubsaet A, Martens M, et al. Systematic prevention of overweight and obesity in adults: a qualitative and quantitative literature analysis. Obes Rev. 2010 ; 11 (5). 371-379
-
(2010)
Obes Rev
, vol.11
, Issue.5
, pp. 371-379
-
-
Kremers, S.1
Reubsaet, A.2
Martens, M.3
-
7
-
-
26844444244
-
Early mortality among medicare beneficiaries undergoing bariatric surgical procedures
-
Flum DR, Salem L, Elrod JAB, Dellinger EP, Cheadle A, Chan L. Early mortality among medicare beneficiaries undergoing bariatric surgical procedures. JAMA. 2005 ; 294 (15). 1903-1908
-
(2005)
JAMA
, vol.294
, Issue.15
, pp. 1903-1908
-
-
Flum, D.R.1
Salem, L.2
Elrod, J.A.B.3
Dellinger, E.P.4
Cheadle, A.5
Chan, L.6
-
8
-
-
26844441917
-
Weighing in on bariatric surgery: Procedure use, readmission rates, and mortality
-
Wolfe BM, Morton JM. Weighing in on bariatric surgery: procedure use, readmission rates, and mortality. JAMA. 2005 ; 294 (15). 1960-1963
-
(2005)
JAMA
, vol.294
, Issue.15
, pp. 1960-1963
-
-
Wolfe, B.M.1
Morton, J.M.2
-
9
-
-
37549037023
-
Orlistat-associated adverse effects and drug interactions: A critical review
-
Filippatos TD, Derdemezis CS, Gazi IF, Nakou ES, Mikhailidis DP, Elisaf MS. Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf. 2008 ; 31 (1). 53-65
-
(2008)
Drug Saf
, vol.31
, Issue.1
, pp. 53-65
-
-
Filippatos, T.D.1
Derdemezis, C.S.2
Gazi, I.F.3
Nakou, E.S.4
Mikhailidis, D.P.5
Elisaf, M.S.6
-
10
-
-
0015871393
-
Long-term use of diethylpropion in obesity
-
McKay RH. Long-term use of diethylpropion in obesity. Curr Med Res Opin. 1973 ; 1 (8). 489-493
-
(1973)
Curr Med Res Opin
, vol.1
, Issue.8
, pp. 489-493
-
-
McKay, R.H.1
-
11
-
-
33645468559
-
Safety of drug therapies used for weight loss and treatment of obesity
-
Ioannides-Demos LL, Proietto J, Tonkin AM, McNeil JJ. Safety of drug therapies used for weight loss and treatment of obesity. Drug Saf. 2006 ; 29 (4). 277-302
-
(2006)
Drug Saf
, vol.29
, Issue.4
, pp. 277-302
-
-
Ioannides-Demos, L.L.1
Proietto, J.2
Tonkin, A.M.3
McNeil, J.J.4
-
12
-
-
34249821944
-
Pharmacological treatment of the overweight patient
-
Bray GA, Greenway FL. Pharmacological treatment of the overweight patient. Pharmacol Rev. 2007 ; 59 (2). 151-184
-
(2007)
Pharmacol Rev
, vol.59
, Issue.2
, pp. 151-184
-
-
Bray, G.A.1
Greenway, F.L.2
-
13
-
-
84890900977
-
-
BELVIQ - 022529lbl.pdf [Internet]. Accessed May 23, 2013
-
BELVIQ - 022529lbl.pdf [Internet];2013. http://www.accessdata.fda.gov/ drugsatfda-docs/label/2012/022529lbl.pdf. Accessed May 23, 2013.
-
(2013)
-
-
-
14
-
-
42449134961
-
Lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist: In vitro and in vivo pharmacological characterization
-
Thomsen WJ, Grottick AJ, Menzaghi F, et al. Lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist: in vitro and in vivo pharmacological characterization. J Pharmacol Exp Ther. 2008 ; 325 (2). 577-587
-
(2008)
J Pharmacol Exp Ther
, vol.325
, Issue.2
, pp. 577-587
-
-
Thomsen, W.J.1
Grottick, A.J.2
Menzaghi, F.3
-
15
-
-
0032505060
-
An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. Sustained-release dexfenfluramine study group
-
Weissman NJ, Tighe JF, Gottdiener JS, Gwynne JT. An assessment of heart-valve abnormalities in obese patients taking dexfenfluramine, sustained-release dexfenfluramine, or placebo. sustained-release dexfenfluramine study group. N Engl J Med. 1998 ; 339 (11). 725-732
-
(1998)
N Engl J Med
, vol.339
, Issue.11
, pp. 725-732
-
-
Weissman, N.J.1
Tighe, J.F.2
Gottdiener, J.S.3
Gwynne, J.T.4
-
16
-
-
84863372539
-
Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin
-
Sadeque AJM, Usmani KA, Palamar S, Cerny MA, Chen WG. Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin. Drug Metab Dispos. 2012 ; 40 (4). 772-778
-
(2012)
Drug Metab Dispos
, vol.40
, Issue.4
, pp. 772-778
-
-
Sadeque, A.J.M.1
Usmani, K.A.2
Palamar, S.3
Cerny, M.A.4
Chen, W.G.5
-
17
-
-
84863345375
-
Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist
-
Usmani KA, Chen WG, Sadeque AJM. Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist. Drug Metab Dispos. 2012 ; 40 (4). 761-771
-
(2012)
Drug Metab Dispos
, vol.40
, Issue.4
, pp. 761-771
-
-
Usmani, K.A.1
Chen, W.G.2
Sadeque, A.J.M.3
-
18
-
-
77954635020
-
Multicenter, placebo-controlled trial of lorcaserin for weight management
-
Smith SR, Weissman NJ, Anderson CM, et al. Multicenter, placebo-controlled trial of lorcaserin for weight management. N Engl J Med. 2010 ; 363 (3). 245-256
-
(2010)
N Engl J Med
, vol.363
, Issue.3
, pp. 245-256
-
-
Smith, S.R.1
Weissman, N.J.2
Anderson, C.M.3
-
19
-
-
80053539943
-
A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: The BLOSSOM trial
-
Fidler MC, Sanchez M, Raether B, et al. A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial. J Clin Endocrinol Metab. 2011 ; 96 (10). 3067-3077
-
(2011)
J Clin Endocrinol Metab
, vol.96
, Issue.10
, pp. 3067-3077
-
-
Fidler, M.C.1
Sanchez, M.2
Raether, B.3
-
20
-
-
84862869642
-
Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: The BLOOM-DM study
-
O'Neil PM, Smith SR, Weissman NJ, et al. Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study. Obesity (Silver Spring). 2012 ; 20 (7). 1426-1436
-
(2012)
Obesity (Silver Spring)
, vol.20
, Issue.7
, pp. 1426-1436
-
-
O'Neil, P.M.1
Smith, S.R.2
Weissman, N.J.3
-
23
-
-
84856246606
-
Controlled-release phentermine/topiramate in severely obese adults: A randomized controlled trial (EQUIP)
-
Allison DB, Gadde KM, Garvey WT, et al. Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP). Obesity (Silver Spring). 2012 ; 20 (2). 330-342
-
(2012)
Obesity (Silver Spring)
, vol.20
, Issue.2
, pp. 330-342
-
-
Allison, D.B.1
Gadde, K.M.2
Garvey, W.T.3
-
24
-
-
79954561234
-
Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): A randomised, placebo-controlled, phase 3 trial
-
Gadde KM, Allison DB, Ryan DH, et al. Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER): a randomised, placebo-controlled, phase 3 trial. Lancet. 2011 ; 377 (9774). 1341-1352
-
(2011)
Lancet
, vol.377
, Issue.9774
, pp. 1341-1352
-
-
Gadde, K.M.1
Allison, D.B.2
Ryan, D.H.3
-
25
-
-
84856388467
-
Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): A randomized, placebo-controlled, phase 3 extension study
-
Garvey WT, Ryan DH, Look M, et al. Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension study. Am J Clin Nutr. 2012 ; 95 (2). 297-308
-
(2012)
Am J Clin Nutr
, vol.95
, Issue.2
, pp. 297-308
-
-
Garvey, W.T.1
Ryan, D.H.2
Look, M.3
-
26
-
-
84876041829
-
Cosentino, Conrad A. Phentermine and topiramate for the management of obesity: A review
-
Uwaifo G. Cosentino, Conrad A. Phentermine and topiramate for the management of obesity: a review. Drug Des Devel Ther. 2011 ; 7: 267-278
-
(2011)
Drug des Devel Ther
, vol.7
, pp. 267-278
-
-
Uwaifo, G.1
-
28
-
-
77956904326
-
Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: The COR-BMOD trial
-
Wadden TA, Foreyt JP, Foster GD, et al. Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification: the COR-BMOD trial. Obesity (Silver Spring). 2011 ; 19 (1). 110-120
-
(2011)
Obesity (Silver Spring)
, vol.19
, Issue.1
, pp. 110-120
-
-
Wadden, T.A.1
Foreyt, J.P.2
Foster, G.D.3
-
29
-
-
77956057548
-
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): A multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
-
Greenway FL, Fujioka K, Plodkowski RA, et al. Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial. Lancet. 2010 ; 376 (9741). 595-605
-
(2010)
Lancet
, vol.376
, Issue.9741
, pp. 595-605
-
-
Greenway, F.L.1
Fujioka, K.2
Plodkowski, R.A.3
-
30
-
-
84879324574
-
A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II)
-
Apovian C, Aronne L, Rubino D, et al. A randomized, phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors (COR-II). Obesity (Silver Spring). 2013 ; 21 (5). 935-943
-
(2013)
Obesity (Silver Spring)
, vol.21
, Issue.5
, pp. 935-943
-
-
Apovian, C.1
Aronne, L.2
Rubino, D.3
-
31
-
-
84890898401
-
-
Accessed June 3, 2013
-
Orexigen Therapeutics, Inc. - Contrave [Internet];2013. http://www.orexigen.com/product-candidates/contrave.html. Accessed June 3, 2013.
-
(2013)
Contrave [Internet]
-
-
-
32
-
-
34548549373
-
Combination therapy of zonisamide and bupropion for weight reduction in obese women: A preliminary, randomized, open-label study
-
Gadde KM, Yonish GM, Foust MS, Wagner HR. Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study. J Clin Psychiatry. 2007 ; 68 (8). 1226-1229
-
(2007)
J Clin Psychiatry
, vol.68
, Issue.8
, pp. 1226-1229
-
-
Gadde, K.M.1
Yonish, G.M.2
Foust, M.S.3
Wagner, H.R.4
-
34
-
-
84890904541
-
-
Press Release [Internet]. Accessed May 23, 2013
-
Orexigen Therapeutics, Inc. - Press Release [Internet]; 2013. http://ir.orexigen.com/phoenix.zhtml?c=207034&p=irol-newsArticle&id= 1400316. Accessed May 23, 2013.
-
(2013)
-
-
-
35
-
-
70350064004
-
The effect of tesofensine on body weight and body composition in obese subjects - Secondary publication [in Danish]. Ugeskr
-
Nielsen A-LH, Larsen TM, Madsbad S, et al. The effect of tesofensine on body weight and body composition in obese subjects - secondary publication [in Danish]. Ugeskr. Laeger. 2009 ; 171 (41). 2974-2977
-
(2009)
Laeger
, vol.171
, Issue.41
, pp. 2974-2977
-
-
A-Lh, N.1
Larsen, T.M.2
Madsbad, S.3
-
36
-
-
67650442032
-
Tesofensine - A novel potent weight loss medicine. Evaluation of: Astrup A, Breum L, Jensen TJ, Kroustrup JP, Larsen TM. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: A randomised, double-blind, placebo-controlled trial. Lancet 2008;372:1906-13
-
Doggrell SA. Tesofensine - a novel potent weight loss medicine. Evaluation of: Astrup A, Breum L, Jensen TJ, Kroustrup JP, Larsen TM. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomised, double-blind, placebo-controlled trial. Lancet 2008;372:1906-13. Expert Opin Investig Drugs. 2009 ; 18 (7). 1043-1046
-
(2009)
Expert Opin Investig Drugs
, vol.18
, Issue.7
, pp. 1043-1046
-
-
Doggrell, S.A.1
-
37
-
-
84890914792
-
Trial irregularities earn Lancet study of potential weight loss drug tesofensine Expression of Concern
-
Accessed May 23, 2013
-
Trial irregularities earn Lancet study of potential weight loss drug tesofensine Expression of Concern. Retraction Watch [Internet]; 2013. http://retractionwatch.wordpress.com/2013/04/09/trial-irregularities-earn- lancet-study-of-potential-weight-loss-drug-tesofensine-expression-of-concern/. Accessed May 23, 2013.
-
(2013)
Retraction Watch [Internet]
-
-
-
38
-
-
0025770610
-
Lower pleasantness of palatable foods in nalmefene-treated human volunteers
-
Yeomans MR, Wright P. Lower pleasantness of palatable foods in nalmefene-treated human volunteers. Appetite. 1991 ; 16 (3). 249-259
-
(1991)
Appetite
, vol.16
, Issue.3
, pp. 249-259
-
-
Yeomans, M.R.1
Wright, P.2
-
39
-
-
0036817344
-
Opioid peptides and the control of human ingestive behaviour
-
Yeomans MR, Gray RW. Opioid peptides and the control of human ingestive behaviour. Neurosci Biobehav Rev. 2002 ; 26 (6). 713-728
-
(2002)
Neurosci Biobehav Rev
, vol.26
, Issue.6
, pp. 713-728
-
-
Yeomans, M.R.1
Gray, R.W.2
-
40
-
-
80053193844
-
Neuropsychiatric adverse effects of centrally acting antiobesity drugs
-
Nathan PJ, O'Neill BV, Napolitano A, Bullmore ET. Neuropsychiatric adverse effects of centrally acting antiobesity drugs. CNS Neurosci Ther. 2011 ; 17 (5). 490-505
-
(2011)
CNS Neurosci Ther
, vol.17
, Issue.5
, pp. 490-505
-
-
Nathan, P.J.1
O'Neill, B.V.2
Napolitano, A.3
Bullmore, E.T.4
-
41
-
-
84870474841
-
Multiple-dose safety, pharmacokinetics, and pharmacodynamics of the μ-opioid receptor inverse agonist GSK1521498
-
Nathan PJ, Bush MA, Tao WX, et al. Multiple-dose safety, pharmacokinetics, and pharmacodynamics of the μ-opioid receptor inverse agonist GSK1521498. J Clin Pharmacol. 2012 ; 52 (10). 1456-1467
-
(2012)
J Clin Pharmacol
, vol.52
, Issue.10
, pp. 1456-1467
-
-
Nathan, P.J.1
Bush, M.A.2
Tao, W.X.3
-
42
-
-
33847261129
-
Cetilistat (ATL-962), a novel lipase inhibitor: A 12-week randomized, placebo-controlled study of weight reduction in obese patients
-
Kopelman P, Bryson A, Hickling R, et al. Cetilistat (ATL-962), a novel lipase inhibitor: a 12-week randomized, placebo-controlled study of weight reduction in obese patients. Int J Obes (Lond). 2007 ; 31 (3). 494-499
-
(2007)
Int J Obes (Lond)
, vol.31
, Issue.3
, pp. 494-499
-
-
Kopelman, P.1
Bryson, A.2
Hickling, R.3
-
43
-
-
73949084345
-
Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: Comparison with orlistat (Xenical)
-
Kopelman P, Groot G de H, Rissanen A, et al. Weight loss, HbA1c reduction, and tolerability of cetilistat in a randomized, placebo-controlled phase 2 trial in obese diabetics: comparison with orlistat (Xenical). Obesity (Silver Spring). 2010 ; 18 (1). 108-115
-
(2010)
Obesity (Silver Spring)
, vol.18
, Issue.1
, pp. 108-115
-
-
Kopelman, P.1
Groot, G.D.H.2
Rissanen, A.3
-
44
-
-
77952584236
-
Central and peripheral molecular targets for antiobesity pharmacotherapy
-
Valentino MA, Lin JE, Waldman SA. Central and peripheral molecular targets for antiobesity pharmacotherapy. Clin Pharmacol Ther. 2010 ; 87 (6). 652-662
-
(2010)
Clin Pharmacol Ther
, vol.87
, Issue.6
, pp. 652-662
-
-
Valentino, M.A.1
Lin, J.E.2
Waldman, S.A.3
-
45
-
-
70350619609
-
Effects of liraglutide in the treatment of obesity: A randomised, double-blind, placebo-controlled study
-
Astrup A, Rössner S, Van Gaal L, et al. Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study. Lancet. 2009 ; 374 (9701). 1606-1616
-
(2009)
Lancet
, vol.374
, Issue.9701
, pp. 1606-1616
-
-
Astrup, A.1
Rössner, S.2
Van Gaal, L.3
-
46
-
-
84890959294
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed May 23, 2013
-
Search of: liraglutide AND obesity - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results?term= liraglutide+AND+obesity&Search=Search. Accessed May 23, 2013.
-
(2013)
Search Of: Liraglutide and Obesity
-
-
-
47
-
-
84859003663
-
Effects of glucagon-like peptide-1 receptor agonists on weight loss: Systematic review and meta-analyses of randomised controlled trials
-
Vilsbøll T, Christensen M, Junker AE, Knop FK, Gluud LL. Effects of glucagon-like peptide-1 receptor agonists on weight loss: systematic review and meta-analyses of randomised controlled trials. BMJ. 2012 ; 344: d7771
-
(2012)
BMJ
, vol.344
, pp. 7771
-
-
Vilsbøll, T.1
Christensen, M.2
Junker, A.E.3
Knop, F.K.4
Gluud, L.L.5
-
48
-
-
84878665802
-
Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans
-
Maciejewski BS, Laperle JL, Chen D, et al. Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans. Am J Physiol Gastrointest Liver Physiol. 2013 ; 304 (11). G958 - G969
-
(2013)
Am J Physiol Gastrointest Liver Physiol
, vol.304
, Issue.11
-
-
Maciejewski, B.S.1
Laperle, J.L.2
Chen, D.3
-
49
-
-
84890934906
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed May 28, 2013
-
Search of: PF-04620110 - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results?term=PF-04620110&Search= Search. Accessed May 28, 2013.
-
(2013)
Search Of: PF-04620110
-
-
-
50
-
-
84890913393
-
-
Zafgen [Internet]. Accessed May 24, 2013
-
The Science - Our Approach - Zafgen [Internet]; 2013. http://zafgen.com/zafgen/our-approach/the-science. Accessed May 24, 2013.
-
(2013)
The Science - Our Approach
-
-
-
51
-
-
84890903923
-
-
Hughes TE, Kim DD, Marjason J, Proietto J, Whitehead JP, Vath JE Obes (Silver Spring). 2013 :
-
(2013)
Obes (Silver Spring)
-
-
Hughes, T.E.1
Kim, D.D.2
Marjason, J.3
Proietto, J.4
Whitehead, J.P.5
Vath, J.E.6
-
52
-
-
84890948495
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed May 24, 2013
-
Search of: beloranib - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results?term=beloranib&Search= Search. Accessed May 24, 2013.
-
(2013)
Search Of: Beloranib
-
-
-
53
-
-
80455143206
-
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
-
Timmers S, Konings E, Bilet L, et al. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 2011 ; 14 (5). 612-622
-
(2011)
Cell Metab
, vol.14
, Issue.5
, pp. 612-622
-
-
Timmers, S.1
Konings, E.2
Bilet, L.3
-
54
-
-
84934442970
-
Angiogenesis in adipose tissue
-
Brakenhielm E, Cao Y. Angiogenesis in adipose tissue. Methods Mol Biol. 2008 ; 456: 65-81
-
(2008)
Methods Mol Biol
, vol.456
, pp. 65-81
-
-
Brakenhielm, E.1
Cao, Y.2
-
55
-
-
76749132016
-
Angiogenesis and development of adipose tissue
-
Christiaens V, Lijnen HR. Angiogenesis and development of adipose tissue. Mol Cell Endocrinol. 2010 ; 318 (1-2). 2-9
-
(2010)
Mol Cell Endocrinol
, vol.318
, Issue.12
, pp. 2-9
-
-
Christiaens, V.1
Lijnen, H.R.2
-
56
-
-
42349093844
-
Angiogenesis and obesity
-
Lijnen HR. Angiogenesis and obesity. Cardiovasc Res. 2008 ; 78 (2). 286-293
-
(2008)
Cardiovasc Res
, vol.78
, Issue.2
, pp. 286-293
-
-
Lijnen, H.R.1
-
57
-
-
27944453623
-
Angiogenic factors are elevated in overweight and obese individuals
-
Silha JV, Krsek M, Sucharda P, Murphy LJ. Angiogenic factors are elevated in overweight and obese individuals. Int J Obes (Lond). 2005 ; 29 (11). 1308-1314
-
(2005)
Int J Obes (Lond)
, vol.29
, Issue.11
, pp. 1308-1314
-
-
Silha, J.V.1
Krsek, M.2
Sucharda, P.3
Murphy, L.J.4
-
58
-
-
84890912652
-
-
npre20116256-1.pdf [Internet]. Accessed May 28, 2013
-
npre20116256-1.pdf [Internet];2013. http://precedings.nature.com/ documents/6256/version/1/files/npre20116256-1.pdf. Accessed May 28, 2013.
-
(2013)
-
-
-
59
-
-
84890956028
-
-
nyhf2-10-hottechnologies-angiolab.pdf [Internet]. Accessed May 28, 2013
-
nyhf2-10-hottechnologies-angiolab.pdf [Internet]; 2013. http://www.nyhf.org/docs/nyhf2-10-hottechnologies-angiolab.pdf. Accessed May 28, 2013.
-
(2013)
-
-
-
60
-
-
79955797302
-
The anti-angiogenic herbal composition Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris regulates obesity in genetically obese ob/ob mice
-
Yoon M, Kim M-Y. The anti-angiogenic herbal composition Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris regulates obesity in genetically obese ob/ob mice. Pharm Biol. 2011 ; 49 (6). 614-619
-
(2011)
Pharm Biol
, vol.49
, Issue.6
, pp. 614-619
-
-
Yoon, M.1
Kim, M.-Y.2
-
63
-
-
84890937122
-
-
Accessed June 1, 2013
-
Orexigen Therapeutics, Inc. - Empatic [Internet]; 2013. http://www.orexigen.com/product-candidates/empatic.html. Accessed June 1, 2013.
-
(2013)
Empatic [Internet]
-
-
-
65
-
-
84890895297
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed June 1, 2013
-
Search of: velneperit - List Results - ClinicalTrials.gov [Internet]; 2013. http://clinicaltrials.gov/ct2/results?term=velneperit&Search=Search. Accessed June 1, 2013.
-
(2013)
Search Of: Velneperit
-
-
-
66
-
-
84890937618
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed June 1, 2013
-
Search of: tesofensine - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results/displayOpt?flds=a&flds= b&flds=f&submit-fld-opt=on&term=tesofensine&show-flds=Y. Accessed June 1, 2013.
-
(2013)
Search Of: Tesofensine
-
-
-
69
-
-
23644443678
-
Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: A double-blind, randomized, controlled trial
-
Wynne K, Park AJ, Small CJ, et al. Subcutaneous oxyntomodulin reduces body weight in overweight and obese subjects: a double-blind, randomized, controlled trial. Diabetes. 2005 ; 54 (8). 2390-2395
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2390-2395
-
-
Wynne, K.1
Park, A.J.2
Small, C.J.3
-
70
-
-
84890933346
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed May 27, 2013
-
Search of: GSK 1521498 - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results/displayOpt?flds=a&flds= b&flds=f&submit-fld-opt=on&term=GSK+1521498&show-flds=Y. Accessed May 27, 2013.
-
(2013)
Search Of: GSK 1521498
-
-
-
71
-
-
84890903825
-
-
Full Text View - ClinicalTrials.gov [Internet]. Accessed June 1, 2013
-
Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement - Full Text View - ClinicalTrials.gov [Internet]; 2013. http://www. clinicaltrials.gov/ct2/show/NCT01039454?term=GSK+598809+AND+obesity&rank=1. Accessed June 1, 2013.
-
(2013)
Effects of the D3 Antagonist GSK598809 on Food Reward and Reinforcement
-
-
-
72
-
-
84890922312
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed June 1, 2013
-
Search of: PF-04971729 AND obesity - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results?term=PF- 04971729+AND+obesity&Search=Search. Accessed June 1, 2013.
-
(2013)
Search Of: PF-04971729 and Obesity
-
-
-
73
-
-
84890951152
-
-
List Results - ClinicalTrials.gov [Internet]. Accessed June 1, 2013
-
Search of: PF-04620110 AND obesity - List Results - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/results?term=PF- 04620110+AND+obesity&Search=Search. Accessed June 1, 2013.
-
(2013)
Search Of: PF-04620110 and Obesity
-
-
-
74
-
-
33750510903
-
The obesity pipeline: Current strategies in the development of anti-obesity drugs
-
Cooke D, Bloom S. The obesity pipeline: current strategies in the development of anti-obesity drugs. Nat Rev Drug Discov. 2006 ; 5 (11). 919-931
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.11
, pp. 919-931
-
-
Cooke, D.1
Bloom, S.2
-
77
-
-
9444287592
-
Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International primary pulmonary hypertension study group
-
Abenhaim L, Moride Y, Brenot F, et al. Appetite-suppressant drugs and the risk of primary pulmonary hypertension. International primary pulmonary hypertension study group. N Engl J Med. 1996 ; 335 (9). 609-616
-
(1996)
N Engl J Med
, vol.335
, Issue.9
, pp. 609-616
-
-
Abenhaim, L.1
Moride, Y.2
Brenot, F.3
-
78
-
-
0032504983
-
A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation
-
Jick H, Vasilakis C, Weinrauch LA, Meier CR, Jick SS, Derby LE. A population-based study of appetite-suppressant drugs and the risk of cardiac-valve regurgitation. N Engl J Med. 1998 ; 339 (11). 719-724
-
(1998)
N Engl J Med
, vol.339
, Issue.11
, pp. 719-724
-
-
Jick, H.1
Vasilakis, C.2
Weinrauch, L.A.3
Meier, C.R.4
Jick, S.S.5
Derby, L.E.6
-
79
-
-
0036911037
-
Effect of fenfluramine-derivative diet pills on cardiac valves: A meta-analysis of observational studies
-
Sachdev M, Miller WC, Ryan T, Jollis JG. Effect of fenfluramine- derivative diet pills on cardiac valves: a meta-analysis of observational studies. Am Heart J. 2002 ; 144 (6). 1065-1073
-
(2002)
Am Heart J
, vol.144
, Issue.6
, pp. 1065-1073
-
-
Sachdev, M.1
Miller, W.C.2
Ryan, T.3
Jollis, J.G.4
-
80
-
-
0034890568
-
Long-term pharmacotherapy of obesity 2000: A review of efficacy and safety
-
Glazer G. Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety. Arch Intern Med. 2001 ; 161 (15). 1814-1824
-
(2001)
Arch Intern Med
, vol.161
, Issue.15
, pp. 1814-1824
-
-
Glazer, G.1
-
81
-
-
0034700436
-
Phenylpropanolamine and the risk of hemorrhagic stroke
-
Kernan WN, Viscoli CM, Brass LM, et al. Phenylpropanolamine and the risk of hemorrhagic stroke. N Engl J Med. 2000 ; 343 (25). 1826-1832
-
(2000)
N Engl J Med
, vol.343
, Issue.25
, pp. 1826-1832
-
-
Kernan, W.N.1
Viscoli, C.M.2
Brass, L.M.3
-
82
-
-
15944367788
-
Meta-analysis: Pharmacologic treatment of obesity
-
Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med. 2005 ; 142 (7). 532-546
-
(2005)
Ann Intern Med
, vol.142
, Issue.7
, pp. 532-546
-
-
Li, Z.1
Maglione, M.2
Tu, W.3
-
83
-
-
34548835744
-
Obesity paradox in patients with hypertension and coronary artery disease
-
Uretsky S, Messerli FH, Bangalore S, et al. Obesity paradox in patients with hypertension and coronary artery disease. Am J Med. 2007 ; 120 (10). 863-870
-
(2007)
Am J Med
, vol.120
, Issue.10
, pp. 863-870
-
-
Uretsky, S.1
Messerli, F.H.2
Bangalore, S.3
-
84
-
-
0342545887
-
Relation of low body mass to death and stroke in the systolic hypertension in the elderly program. The SHEP cooperative research group
-
Wassertheil-Smoller S, Fann C, Allman RM, et al. Relation of low body mass to death and stroke in the systolic hypertension in the elderly program. The SHEP cooperative research group. Arch Intern Med. 2000 ; 160 (4). 494-500
-
(2000)
Arch Intern Med
, vol.160
, Issue.4
, pp. 494-500
-
-
Wassertheil-Smoller, S.1
Fann, C.2
Allman, R.M.3
-
85
-
-
84877935534
-
Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
-
Lavie CJ, Alpert MA, Arena R, Mehra MR, Milani RV, Ventura HO. Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure. JACC Heart Fail. 2013 ; 1 (2). 93-102
-
(2013)
JACC Heart Fail
, vol.1
, Issue.2
, pp. 93-102
-
-
Lavie, C.J.1
Alpert, M.A.2
Arena, R.3
Mehra, M.R.4
Milani, R.V.5
Ventura, H.O.6
-
86
-
-
84871784819
-
Association of all-cause mortality with overweight and obesity using standard body mass index categories: A systematic review and meta-analysis
-
Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. JAMA. 2013 ; 309 (1). 71-82
-
(2013)
JAMA
, vol.309
, Issue.1
, pp. 71-82
-
-
Flegal, K.M.1
Kit, B.K.2
Orpana, H.3
Graubard, B.I.4
-
87
-
-
33845348932
-
ADHERE Scientific Advisory Committee and Investigators. An obesity paradox in acute heart failure: Analysis of body mass index and inhospital mortality for 108,927 patients in the acute decompensated heart failure national registry
-
Fonarow GC, Srikanthan P, Costanzo MR, Cintron GB, Lopatin M. ADHERE Scientific Advisory Committee and Investigators. An obesity paradox in acute heart failure: analysis of body mass index and inhospital mortality for 108,927 patients in the acute decompensated heart failure national registry. Am Heart J. 2007 ; 153 (1). 74-81
-
(2007)
Am Heart J
, vol.153
, Issue.1
, pp. 74-81
-
-
Fonarow, G.C.1
Srikanthan, P.2
Costanzo, M.R.3
Cintron, G.B.4
Lopatin, M.5
-
88
-
-
77649180090
-
Value of weight reduction in patients with cardiovascular disease
-
Artham SM, Lavie CJ, Milani RV, Ventura HO. Value of weight reduction in patients with cardiovascular disease. Curr Treat Options Cardiovasc Med. 2010 ; 12 (1). 21-35
-
(2010)
Curr Treat Options Cardiovasc Med
, vol.12
, Issue.1
, pp. 21-35
-
-
Artham, S.M.1
Lavie, C.J.2
Milani, R.V.3
Ventura, H.O.4
-
89
-
-
36048995288
-
Efficacy and safety of the weight-loss drug rimonabant: A meta-analysis of randomised trials
-
Christensen R, Kristensen PK, Bartels EM, Bliddal H, Astrup A. Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet. 2007 ; 370 (9600). 1706-1713
-
(2007)
Lancet
, vol.370
, Issue.9600
, pp. 1706-1713
-
-
Christensen, R.1
Kristensen, P.K.2
Bartels, E.M.3
Bliddal, H.4
Astrup, A.5
-
90
-
-
36049006465
-
Depression and anxiety with rimonabant
-
Mitchell PB, Morris MJ. Depression and anxiety with rimonabant. Lancet. 2007 ; 370 (9600). 1671-1672
-
(2007)
Lancet
, vol.370
, Issue.9600
, pp. 1671-1672
-
-
Mitchell, P.B.1
Morris, M.J.2
-
91
-
-
77956284607
-
Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects
-
James WPT, Caterson ID, Coutinho W, et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med. 2010 ; 363 (10). 905-917
-
(2010)
N Engl J Med
, vol.363
, Issue.10
, pp. 905-917
-
-
James, W.P.T.1
Caterson, I.D.2
Coutinho, W.3
-
93
-
-
84890939017
-
-
Proefschrift Edwin Parlevliet 180810-06.pdf [Internet]. Accessed May 24, 2013
-
Proefschrift Edwin Parlevliet 180810-06.pdf [Internet]; 2013. https://openaccess.leidenuniv.nl/bitstream/handle/1887/16080/06.pdf?sequence=9. Accessed May 24, 2013.
-
(2013)
-
-
-
94
-
-
84890931780
-
-
Full Text View - ClinicalTrials.gov [Internet]. Accessed June 3, 2013
-
A Weight Loss Study in Overweight Men and Women - Full Text View - ClinicalTrials.gov [Internet]; 2013. http://www.clinicaltrials.gov/ct2/show/ NCT00993421?term=LY377604&rank=1. Accessed June 3, 2013.
-
(2013)
A Weight Loss Study in Overweight Men and Women
-
-
-
95
-
-
53849090615
-
Effect of histaminergic manipulation on weight in obese adults: A randomized placebo controlled trial
-
Barak N, Greenway FL, Fujioka K, Aronne LJ, Kushner RF. Effect of histaminergic manipulation on weight in obese adults: a randomized placebo controlled trial. Int J Obes (Lond). 2008 ; 32 (10). 1559-1565
-
(2008)
Int J Obes (Lond)
, vol.32
, Issue.10
, pp. 1559-1565
-
-
Barak, N.1
Greenway, F.L.2
Fujioka, K.3
Aronne, L.J.4
Kushner, R.F.5
-
96
-
-
78651291604
-
Acute effects of betahistine hydrochloride on food intake and appetite in obese women: A randomized, placebo-controlled trial
-
Ali AH, Yanoff LB, Stern EA, et al. Acute effects of betahistine hydrochloride on food intake and appetite in obese women: a randomized, placebo-controlled trial. Am J Clin Nutr. 2010 ; 92 (6). 1290-1297
-
(2010)
Am J Clin Nutr
, vol.92
, Issue.6
, pp. 1290-1297
-
-
Ali, A.H.1
Yanoff, L.B.2
Stern, E.A.3
-
97
-
-
77952290161
-
A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: A high-dose study
-
Aronne LJ, Tonstad S, Moreno M, et al. A clinical trial assessing the safety and efficacy of taranabant, a CB1R inverse agonist, in obese and overweight patients: a high-dose study. Int J Obes (Lond). 2010 ; 34 (5). 919-935
-
(2010)
Int J Obes (Lond)
, vol.34
, Issue.5
, pp. 919-935
-
-
Aronne, L.J.1
Tonstad, S.2
Moreno, M.3
-
98
-
-
70450245171
-
Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: Energy intake predicts lack of weight loss efficacy
-
Krishna R, Gumbiner B, Stevens C, et al. Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy. Clin Pharmacol Ther. 2009 ; 86 (6). 659-66
-
(2009)
Clin Pharmacol Ther
, vol.86
, Issue.6
, pp. 659-666
-
-
Krishna, R.1
Gumbiner, B.2
Stevens, C.3
-
99
-
-
70849120492
-
Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders
-
Heal DJ, Gosden J, Smith SL. Regulatory challenges for new drugs to treat obesity and comorbid metabolic disorders. Br J Clin Pharmacol. 2009 ; 68 (6). 861-874
-
(2009)
Br J Clin Pharmacol
, vol.68
, Issue.6
, pp. 861-874
-
-
Heal, D.J.1
Gosden, J.2
Smith, S.L.3
-
100
-
-
84890940349
-
-
Adopted - WC500003264.pdf [Internet]. Accessed June 3, 2013
-
Guideline on Weight Control - Adopted - WC500003264.pdf [Internet]; 2013. http://www.ema.europa.eu/docs/en-GB/document-library/Scientific-guideline/2009/ 09/WC500003264.pdf. Accessed June 3, 2013.
-
(2013)
Guideline on Weight Control
-
-
|