메뉴 건너뛰기




Volumn 114, Issue , 2015, Pages 114-124

Accessing biological actions of Ganoderma secondary metabolites by in silico profiling

Author keywords

Antiviral targets; Ganoderma lucidum; Ganodermataceae; Metabolic syndrome; Pharmacophore profiling; Triterpenes; Virtual screening

Indexed keywords

FUNGI; GANODERMA; GANODERMA LUCIDUM; GANODERMATACEAE;

EID: 84929705249     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2014.10.010     Document Type: Article
Times cited : (33)

References (94)
  • 1
    • 84929708857 scopus 로고    scopus 로고
    • Accelrys Software Inc. Accelrys Software Inc. San Diego
    • Accelrys Software Inc. Pipeline Pilot, Release 8.5 2011 Accelrys Software Inc. San Diego
    • (2011) Pipeline Pilot, Release 8.5
  • 3
    • 84869741000 scopus 로고    scopus 로고
    • Current progress in the treatment of chronic hepatitis C
    • A. Alexopoulou, and G.V. Papatheodoridis Current progress in the treatment of chronic hepatitis C World J. Gastroenterol. 18 2012 6060 6069
    • (2012) World J. Gastroenterol. , vol.18 , pp. 6060-6069
    • Alexopoulou, A.1    Papatheodoridis, G.V.2
  • 9
    • 74549148035 scopus 로고    scopus 로고
    • Cholesteryl ester transfer protein: At the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
    • M.J. Chapman, W. Le Goff, M. Guerin, and A. Kontush Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors Eur. Heart J. 31 2010 149 164
    • (2010) Eur. Heart J. , vol.31 , pp. 149-164
    • Chapman, M.J.1    Le Goff, W.2    Guerin, M.3    Kontush, A.4
  • 12
    • 47549085997 scopus 로고    scopus 로고
    • Anti-HIV-1 protease activity of lanostane triterpenes from the Vietnamese mushroom Ganoderma colossum
    • R.S. El Dine, A.M. El Halawany, C.-M. Ma, and M. Hattori Anti-HIV-1 protease activity of lanostane triterpenes from the Vietnamese mushroom Ganoderma colossum J. Nat. Prod. 71 2008 1022 1026
    • (2008) J. Nat. Prod. , vol.71 , pp. 1022-1026
    • El Dine, R.S.1    El Halawany, A.M.2    Ma, C.-M.3    Hattori, M.4
  • 13
    • 73349119388 scopus 로고    scopus 로고
    • Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum
    • R.S. El Dine, A.M. El Halawany, C.-M. Ma, and M. Hattori Inhibition of the dimerization and active site of HIV-1 protease by secondary metabolites from the Vietnamese mushroom Ganoderma colossum J. Nat. Prod. 72 2009 2019 2023
    • (2009) J. Nat. Prod. , vol.72 , pp. 2019-2023
    • El Dine, R.S.1    El Halawany, A.M.2    Ma, C.-M.3    Hattori, M.4
  • 15
    • 0032692479 scopus 로고    scopus 로고
    • Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum
    • S.K. Eo, Y.S. Kim, C.K. Lee, and S.S. Han Antiviral activities of various water and methanol soluble substances isolated from Ganoderma lucidum J. Ethnopharmacol. 68 1999 129 136
    • (1999) J. Ethnopharmacol. , vol.68 , pp. 129-136
    • Eo, S.K.1    Kim, Y.S.2    Lee, C.K.3    Han, S.S.4
  • 18
    • 78549231564 scopus 로고    scopus 로고
    • Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum
    • S. Fatmawati, K. Shimizu, and R. Kondo Ganoderic acid Df, a new triterpenoid with aldose reductase inhibitory activity from the fruiting body of Ganoderma lucidum Fitoterapia 81 2010 1033 1036
    • (2010) Fitoterapia , vol.81 , pp. 1033-1036
    • Fatmawati, S.1    Shimizu, K.2    Kondo, R.3
  • 19
    • 77958579745 scopus 로고    scopus 로고
    • Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum
    • S. Fatmawati, K. Shimizu, and R. Kondo Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum Planta Med. 76 2010 1691 1693
    • (2010) Planta Med. , vol.76 , pp. 1691-1693
    • Fatmawati, S.1    Shimizu, K.2    Kondo, R.3
  • 20
    • 81255157445 scopus 로고    scopus 로고
    • Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors
    • S. Fatmawati, K. Shimizu, and R. Kondo Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors Bioorg. Med. Chem. Lett. 21 2011 7295 7297
    • (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 7295-7297
    • Fatmawati, S.1    Shimizu, K.2    Kondo, R.3
  • 21
    • 0037208308 scopus 로고    scopus 로고
    • Property distributions: Differences between drugs, natural products, and molecules from combinatorial chemistry
    • M. Feher, and J.M. Schmidt Property distributions: differences between drugs, natural products, and molecules from combinatorial chemistry J. Chem. Inf. Model. 43 2003 218 227
    • (2003) J. Chem. Inf. Model. , vol.43 , pp. 218-227
    • Feher, M.1    Schmidt, J.M.2
  • 23
    • 84856223129 scopus 로고    scopus 로고
    • PASS-assisted exploration of new therapeutic potential of natural products
    • R.K. Goel, D. Singh, A. Lagunin, and V. Poroikov PASS-assisted exploration of new therapeutic potential of natural products Med. Chem. Res. 20 2011 1509 1514
    • (2011) Med. Chem. Res. , vol.20 , pp. 1509-1514
    • Goel, R.K.1    Singh, D.2    Lagunin, A.3    Poroikov, V.4
  • 24
    • 84877581057 scopus 로고    scopus 로고
    • Emerging low-density lipoprotein therapies: Microsomal triglyceride transfer protein inhibitors
    • A.C. Goldberg Emerging low-density lipoprotein therapies: microsomal triglyceride transfer protein inhibitors J. Clin. Lipidol. 7 2013 16 20
    • (2013) J. Clin. Lipidol. , vol.7 , pp. 16-20
    • Goldberg, A.C.1
  • 26
    • 0842277242 scopus 로고    scopus 로고
    • Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
    • S.M. Grundy, H.B. Brewer Jr., J.I. Cleeman, S.C. Smith Jr., C. Lenfant, A. American Heart, L. National Heart, and I. Blood Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition Circulation 109 2004 433 438
    • (2004) Circulation , vol.109 , pp. 433-438
    • Grundy, S.M.1    Brewer, Jr.H.B.2    Cleeman, J.I.3    Smith, Jr.S.C.4    Lenfant, C.5    American Heart, A.6    National Heart, L.7    Blood, I.8
  • 27
    • 84869987609 scopus 로고    scopus 로고
    • Conformer generation with OMEGA: Learning from the data set and the analysis of failures
    • P.C. Hawkins, and A. Nicholls Conformer generation with OMEGA: learning from the data set and the analysis of failures J. Chem. Inf. Model. 52 2012 2919 2936
    • (2012) J. Chem. Inf. Model. , vol.52 , pp. 2919-2936
    • Hawkins, P.C.1    Nicholls, A.2
  • 28
    • 77951986384 scopus 로고    scopus 로고
    • Conformer generation with OMEGA: Algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database
    • P.C.D. Hawkins, A.G. Skillman, G.L. Warren, B.A. Ellingson, and M.T. Stahl Conformer generation with OMEGA: algorithm and validation using high quality structures from the Protein Databank and Cambridge Structural Database J. Chem. Inf. Model. 50 2010 572 584
    • (2010) J. Chem. Inf. Model. , vol.50 , pp. 572-584
    • Hawkins, P.C.D.1    Skillman, A.G.2    Warren, G.L.3    Ellingson, B.A.4    Stahl, M.T.5
  • 29
    • 70749093851 scopus 로고    scopus 로고
    • Inhibition of subgenomic hepatitis C virus RNA transcription by Chinese herbal extracts
    • S.-P. Huang, G.-J. Shieh, J.-L. Ko, Z.-Y. Weng, J.-G. Lin, and J.-C. Chen Inhibition of subgenomic hepatitis C virus RNA transcription by Chinese herbal extracts Pharm. Biol. 47 2009 111 119
    • (2009) Pharm. Biol. , vol.47 , pp. 111-119
    • Huang, S.-P.1    Shieh, G.-J.2    Ko, J.-L.3    Weng, Z.-Y.4    Lin, J.-G.5    Chen, J.-C.6
  • 30
    • 80053510130 scopus 로고    scopus 로고
    • Ganoderma lucidum spore lipid induces peroxisome proliferator-activated receptor alpha activity
    • Z. Huang, F. Fang, and C.-W. Wong Ganoderma lucidum spore lipid induces peroxisome proliferator-activated receptor alpha activity J. Food Biochem. 35 2011 1508 1513
    • (2011) J. Food Biochem. , vol.35 , pp. 1508-1513
    • Huang, Z.1    Fang, F.2    Wong, C.-W.3
  • 32
    • 25144502105 scopus 로고    scopus 로고
    • Inhibitory effects of Ganoderma applanatum on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues
    • S.H. Jung, Y.S. Lee, S.H. Shim, S. Lee, K.H. Shin, J.S. Kim, Y.S. Kim, and S.S. Kang Inhibitory effects of Ganoderma applanatum on rat lens aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues Phytother. Res. 19 2005 477 480
    • (2005) Phytother. Res. , vol.19 , pp. 477-480
    • Jung, S.H.1    Lee, Y.S.2    Shim, S.H.3    Lee, S.4    Shin, K.H.5    Kim, J.S.6    Kim, Y.S.7    Kang, S.S.8
  • 33
    • 0023806613 scopus 로고
    • Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR)
    • Y. Kabir, S. Kimura, and T. Tamura Dietary effect of Ganoderma lucidum mushroom on blood pressure and lipid levels in spontaneously hypertensive rats (SHR) J. Nutr. Sci. Vitaminol. 34 1988 433 438
    • (1988) J. Nutr. Sci. Vitaminol. , vol.34 , pp. 433-438
    • Kabir, Y.1    Kimura, S.2    Tamura, T.3
  • 34
    • 0034876734 scopus 로고    scopus 로고
    • Studies on Ganoderma lucidum - III the effects of Rokkaku reishi extract on arterial pressure level and serum glucose level
    • Y. Kagaya, S. Hatakeyama, T. Goto, N. Miura, N. Tsujimura, and K. Sakamoto Studies on Ganoderma lucidum - III the effects of Rokkaku reishi extract on arterial pressure level and serum glucose level Res. Commun. Pharmacol. Toxicol. 6 2001 135 138
    • (2001) Res. Commun. Pharmacol. Toxicol. , vol.6 , pp. 135-138
    • Kagaya, Y.1    Hatakeyama, S.2    Goto, T.3    Miura, N.4    Tsujimura, N.5    Sakamoto, K.6
  • 35
    • 84887921509 scopus 로고    scopus 로고
    • Influenza treatment and prophylaxis with neuraminidase inhibitors: A review
    • A. Kamali, and M. Holodniy Influenza treatment and prophylaxis with neuraminidase inhibitors: a review Infect. Drug Resist. 6 2013 187 198
    • (2013) Infect. Drug Resist. , vol.6 , pp. 187-198
    • Kamali, A.1    Holodniy, M.2
  • 37
    • 0038634342 scopus 로고    scopus 로고
    • Inhibition of cytopathic effect of human immunodeficiency virus-1 by water-soluble extract of Ganoderma lucidum
    • H.W. Kim, M.J. Shim, E.C. Choi, and B.K. Kim Inhibition of cytopathic effect of human immunodeficiency virus-1 by water-soluble extract of Ganoderma lucidum Arch. Pharm. Res. 20 1997 425 431
    • (1997) Arch. Pharm. Res. , vol.20 , pp. 425-431
    • Kim, H.W.1    Shim, M.J.2    Choi, E.C.3    Kim, B.K.4
  • 38
    • 2442618838 scopus 로고    scopus 로고
    • The weight of leptin in immunity
    • A. La Cava, and G. Matarese The weight of leptin in immunity Nat. Rev. Immunol. 4 2004 371 379
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 371-379
    • La Cava, A.1    Matarese, G.2
  • 39
    • 78650078527 scopus 로고    scopus 로고
    • Anti-human papillomavirus (HPV) 16 E6 activity of Ling Zhi or reishi medicinal mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) extracts
    • L.K. Lai, N.Z. Abidin, N. Abdullah, and V. Sabaratnam Anti-human papillomavirus (HPV) 16 E6 activity of Ling Zhi or reishi medicinal mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae) extracts Int. J. Med. Mushrooms 12 2010 279 286
    • (2010) Int. J. Med. Mushrooms , vol.12 , pp. 279-286
    • Lai, L.K.1    Abidin, N.Z.2    Abdullah, N.3    Sabaratnam, V.4
  • 40
    • 23844513422 scopus 로고    scopus 로고
    • Expanding the ChemGPS chemical space with natural products
    • J. Larsson, J. Gottfries, L. Bohlin, and A. Backlund Expanding the ChemGPS chemical space with natural products J. Nat. Prod. 68 2005 985 991
    • (2005) J. Nat. Prod. , vol.68 , pp. 985-991
    • Larsson, J.1    Gottfries, J.2    Bohlin, L.3    Backlund, A.4
  • 41
    • 1842509981 scopus 로고    scopus 로고
    • VP1 sequencing of all human rhinovirus serotypes: Insights into genus phylogeny and susceptibility to antiviral capsid-binding compounds
    • R.M. Ledford, N.R. Patel, T.M. Demenczuk, A. Watanyar, T. Herbertz, M.S. Collett, and D.C. Pevear VP1 sequencing of all human rhinovirus serotypes: insights into genus phylogeny and susceptibility to antiviral capsid-binding compounds J. Virol. 78 2004 3663 3674
    • (2004) J. Virol. , vol.78 , pp. 3663-3674
    • Ledford, R.M.1    Patel, N.R.2    Demenczuk, T.M.3    Watanyar, A.4    Herbertz, T.5    Collett, M.S.6    Pevear, D.C.7
  • 42
    • 0025033642 scopus 로고
    • Cardiovascular effects of mycelium extract of Ganoderma lucidum: Inhibition of sympathetic outflow as a mechanism of its hypotensive action
    • S.Y. Lee, and H.M. Rhee Cardiovascular effects of mycelium extract of Ganoderma lucidum: inhibition of sympathetic outflow as a mechanism of its hypotensive action Chem. Pharm. Bull. 38 1990 1359 1364
    • (1990) Chem. Pharm. Bull. , vol.38 , pp. 1359-1364
    • Lee, S.Y.1    Rhee, H.M.2
  • 43
    • 33746175355 scopus 로고    scopus 로고
    • Constituents from the fruiting bodies of Ganoderma applanatum and their aldose reductase inhibitory activity
    • S.H. Lee, S.H. Shim, J.S. Kim, and S.S. Kang Constituents from the fruiting bodies of Ganoderma applanatum and their aldose reductase inhibitory activity Arch. Pharm. Res. 29 2006 479 483
    • (2006) Arch. Pharm. Res. , vol.29 , pp. 479-483
    • Lee, S.H.1    Shim, S.H.2    Kim, J.S.3    Kang, S.S.4
  • 44
    • 33750010694 scopus 로고    scopus 로고
    • New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum
    • C. Li, Y. Li, and H.H. Sun New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum Nat. Prod. Res. 20 2006 985 991
    • (2006) Nat. Prod. Res. , vol.20 , pp. 985-991
    • Li, C.1    Li, Y.2    Sun, H.H.3
  • 46
    • 84862804812 scopus 로고    scopus 로고
    • Quantitative determination of the representative triterpenoids in the extracts of Ganoderma lucidum with different growth stages using high-performance liquid chromatography for evaluation of their 5α-reductase inhibitory properties
    • J. Liu, K. Kurashiki, A. Fukuta, S. Kaneko, Y. Suimi, K. Shimizu, and R. Kondo Quantitative determination of the representative triterpenoids in the extracts of Ganoderma lucidum with different growth stages using high-performance liquid chromatography for evaluation of their 5α-reductase inhibitory properties Food Chem. 133 2012 1034 1038
    • (2012) Food Chem. , vol.133 , pp. 1034-1038
    • Liu, J.1    Kurashiki, K.2    Fukuta, A.3    Kaneko, S.4    Suimi, Y.5    Shimizu, K.6    Kondo, R.7
  • 51
    • 34250851524 scopus 로고    scopus 로고
    • Identification of protein fold topology shared between different folds inhibited by natural products
    • B.M. McArdle, and R.J. Quinn Identification of protein fold topology shared between different folds inhibited by natural products ChemBioChem 8 2007 788 798
    • (2007) ChemBioChem , vol.8 , pp. 788-798
    • McArdle, B.M.1    Quinn, R.J.2
  • 52
    • 0031795507 scopus 로고    scopus 로고
    • Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease
    • B.S. Min, N. Nakamura, H. Miyashiro, K.W. Bae, and M. Hattori Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease Chem. Pharm. Bull. 46 1998 1607 1612
    • (1998) Chem. Pharm. Bull. , vol.46 , pp. 1607-1612
    • Min, B.S.1    Nakamura, N.2    Miyashiro, H.3    Bae, K.W.4    Hattori, M.5
  • 54
    • 80052427759 scopus 로고    scopus 로고
    • Anti-diabetic and some hematological effects of ethylacetate and n-butanol fractions of Ganoderma lucidum aqueous extract in alloxan - Induced diabetic Wister rats
    • A. Mohammed, A.B. Adelaiye, A.G. Bakari, and M.A. Mabrouk Anti-diabetic and some hematological effects of ethylacetate and n-butanol fractions of Ganoderma lucidum aqueous extract in alloxan - induced diabetic Wister rats Int. J. Med. Med. Sci. 1 2009 530 535
    • (2009) Int. J. Med. Med. Sci. , vol.1 , pp. 530-535
    • Mohammed, A.1    Adelaiye, A.B.2    Bakari, A.G.3    Mabrouk, M.A.4
  • 56
    • 52949116851 scopus 로고    scopus 로고
    • Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells
    • H. Nambu, E. Kubo, Y. Takamura, S. Tsuzuki, M. Tamura, and Y. Akagi Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells Diab. Res. Clin. Pract. 82 2008 18 24
    • (2008) Diab. Res. Clin. Pract. , vol.82 , pp. 18-24
    • Nambu, H.1    Kubo, E.2    Takamura, Y.3    Tsuzuki, S.4    Tamura, M.5    Akagi, Y.6
  • 59
    • 84856335862 scopus 로고    scopus 로고
    • Tissue-specific modulation of mineralocorticoid receptor function by 11beta-hydroxysteroid dehydrogenases: An overview
    • A. Odermatt, and D.V. Kratschmar Tissue-specific modulation of mineralocorticoid receptor function by 11beta-hydroxysteroid dehydrogenases: an overview Mol. Cell. Endocrinol. 350 2012 168 186
    • (2012) Mol. Cell. Endocrinol. , vol.350 , pp. 168-186
    • Odermatt, A.1    Kratschmar, D.V.2
  • 60
    • 84929703445 scopus 로고    scopus 로고
    • OMEGA version 2.3.2., 2008. OpenEye Scientific Software: Santa Fe, NM.
    • OMEGA version 2.3.2., 2008. OpenEye Scientific Software: Santa Fe, NM. http://www.eyesopen.com.
  • 61
    • 84897051429 scopus 로고    scopus 로고
    • Structural characterization and bioactivity evaluation of an acidic proteoglycan extract from Ganoderma lucidum fruiting bodies for PTP1B inhibition and anti-diabetes
    • D. Pan, L. Wang, B. Hu, and P. Zhou Structural characterization and bioactivity evaluation of an acidic proteoglycan extract from Ganoderma lucidum fruiting bodies for PTP1B inhibition and anti-diabetes Biopolymers 101 2014 613 623
    • (2014) Biopolymers , vol.101 , pp. 613-623
    • Pan, D.1    Wang, L.2    Hu, B.3    Zhou, P.4
  • 62
    • 33748091693 scopus 로고    scopus 로고
    • Ganoderma - A therapeutic fungal biofactory
    • R.R.M. Paterson Ganoderma - a therapeutic fungal biofactory Phytochemistry 67 2006 1985 2001
    • (2006) Phytochemistry , vol.67 , pp. 1985-2001
    • Paterson, R.R.M.1
  • 63
    • 84929703818 scopus 로고    scopus 로고
    • PerkinElmer, 2008. ChemBioDraw Ultra 11.0, Waltham, MA.
    • PerkinElmer, 2008. ChemBioDraw Ultra 11.0, Waltham, MA.
  • 64
    • 63049086100 scopus 로고    scopus 로고
    • Accessing target information by virtual parallel screening - The impact on natural product research
    • J.M. Rollinger Accessing target information by virtual parallel screening - the impact on natural product research Phytochem. Lett. 2 2009 53 58
    • (2009) Phytochem. Lett. , vol.2 , pp. 53-58
    • Rollinger, J.M.1
  • 65
    • 84974712645 scopus 로고    scopus 로고
    • Computational approaches for the discovery of natural lead structures
    • 2nd ed. CRC Press
    • J.M. Rollinger, and G. Wolber Computational approaches for the discovery of natural lead structures Bioactive Compounds from Natural Sources 2nd ed. 2011 CRC Press 97 132
    • (2011) Bioactive Compounds from Natural Sources , pp. 97-132
    • Rollinger, J.M.1    Wolber, G.2
  • 68
    • 66449136313 scopus 로고    scopus 로고
    • Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense
    • N. Sato, C.-M. Ma, K. Komatsu, and M. Hattori Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense J. Nat. Prod. 72 2009 958 961
    • (2009) J. Nat. Prod. , vol.72 , pp. 958-961
    • Sato, N.1    Ma, C.-M.2    Komatsu, K.3    Hattori, M.4
  • 69
    • 78650750102 scopus 로고    scopus 로고
    • 3D pharmacophores as tools for activity profiling
    • D. Schuster 3D pharmacophores as tools for activity profiling Drug Discovery Today: Technol. 7 2010 205 211
    • (2010) Drug Discovery Today: Technol. , vol.7 , pp. 205-211
    • Schuster, D.1
  • 70
    • 33745221417 scopus 로고    scopus 로고
    • The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening
    • D. Schuster, E.M. Maurer, C. Laggner, L.G. Nashev, T. Wilckens, T. Langer, and A. Odermatt The discovery of new 11beta-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening J. Med. Chem. 49 2006 3454 3466
    • (2006) J. Med. Chem. , vol.49 , pp. 3454-3466
    • Schuster, D.1    Maurer, E.M.2    Laggner, C.3    Nashev, L.G.4    Wilckens, T.5    Langer, T.6    Odermatt, A.7
  • 76
    • 79551664967 scopus 로고    scopus 로고
    • Effect of Ganoderma lucidum extract on adipocyte differentiation and adiponectin gene expression in the murine pre-adipocyte cell line, 3T3-L1
    • Y. Shimojo, K. Kosaka, and T. Shirasawa Effect of Ganoderma lucidum extract on adipocyte differentiation and adiponectin gene expression in the murine pre-adipocyte cell line, 3T3-L1 Phytother. Res. 25 2011 202 207
    • (2011) Phytother. Res. , vol.25 , pp. 202-207
    • Shimojo, Y.1    Kosaka, K.2    Shirasawa, T.3
  • 77
    • 5444268798 scopus 로고    scopus 로고
    • Influenza virus neuraminidase inhibitors: Generation and comparison of structure-based and common feature pharmacophore hypotheses and their application in virtual screening
    • T. Steindl, and T. Langer Influenza virus neuraminidase inhibitors: generation and comparison of structure-based and common feature pharmacophore hypotheses and their application in virtual screening J. Chem. Inf. Comput. Sci. 44 2004 1849 1856
    • (2004) J. Chem. Inf. Comput. Sci. , vol.44 , pp. 1849-1856
    • Steindl, T.1    Langer, T.2
  • 78
    • 20544475681 scopus 로고    scopus 로고
    • Docking versus pharmacophore model generation: A comparison of high-throughput virtual screening strategies for the search of human rhinovirus coat protein inhibitors
    • T. Steindl, and T. Langer Docking versus pharmacophore model generation: a comparison of high-throughput virtual screening strategies for the search of human rhinovirus coat protein inhibitors QSAR Comb. Sci. 24 2005 470 479
    • (2005) QSAR Comb. Sci. , vol.24 , pp. 470-479
    • Steindl, T.1    Langer, T.2
  • 79
    • 26444452660 scopus 로고    scopus 로고
    • Pharmacophore modelling, docking, and principal component analysis-based clustering: Combined computer-assisted approaches to identify new inhibitors of the human rhino virus coat protein
    • T.M. Steindl, C.E. Crump, F.G. Hayden, and T. Langer Pharmacophore modelling, docking, and principal component analysis-based clustering: combined computer-assisted approaches to identify new inhibitors of the human rhino virus coat protein J. Med. Chem. 48 2005 6250 6260
    • (2005) J. Med. Chem. , vol.48 , pp. 6250-6260
    • Steindl, T.M.1    Crump, C.E.2    Hayden, F.G.3    Langer, T.4
  • 80
    • 33750339874 scopus 로고    scopus 로고
    • Parallel screening: A novel concept in pharmacophore modeling and virtual screening
    • T.M. Steindl, D. Schuster, C. Laggner, and T. Langer Parallel screening: a novel concept in pharmacophore modeling and virtual screening J. Chem. Inf. Model. 46 2006 2146 2157
    • (2006) J. Chem. Inf. Model. , vol.46 , pp. 2146-2157
    • Steindl, T.M.1    Schuster, D.2    Laggner, C.3    Langer, T.4
  • 81
    • 33947576378 scopus 로고    scopus 로고
    • High-throughput structure-based pharmacophore modelling as a basis for successful parallel virtual screening
    • T.M. Steindl, D. Schuster, G. Wolber, C. Laggner, and T. Langer High-throughput structure-based pharmacophore modelling as a basis for successful parallel virtual screening J. Comput.-Aided Mol. Des. 20 2006 703 715
    • (2006) J. Comput.-Aided Mol. Des. , vol.20 , pp. 703-715
    • Steindl, T.M.1    Schuster, D.2    Wolber, G.3    Laggner, C.4    Langer, T.5
  • 82
    • 0040675558 scopus 로고    scopus 로고
    • Is the widely used medicinal fungus the Ganoderma lucidum (Fr.) Karst. Sensu stricto?
    • G. Szedlay Is the widely used medicinal fungus the Ganoderma lucidum (Fr.) Karst. sensu stricto? Acta Microbiol. Immunol. Hung. 49 2002 235 243
    • (2002) Acta Microbiol. Immunol. Hung. , vol.49 , pp. 235-243
    • Szedlay, G.1
  • 83
    • 84863847452 scopus 로고    scopus 로고
    • Aldose reductase, oxidative stress, and diabetic mellitus
    • W.H. Tang, K.A. Martin, and J. Hwa Aldose reductase, oxidative stress, and diabetic mellitus Front. Pharmacol. 3 2012 87
    • (2012) Front. Pharmacol. , vol.3 , pp. 87
    • Tang, W.H.1    Martin, K.A.2    Hwa, J.3
  • 84
    • 79959230834 scopus 로고    scopus 로고
    • A protein tyrosine phosphatase 1B activity inhibitor from the fruiting bodies of Ganoderma lucidum (Fr.) Karst and its hypoglycemic potency on streptozotocin-induced type 2 diabetic mice
    • B.S. Teng, C.D. Wang, H.J. Yang, J.S. Wu, D. Zhang, M. Zheng, Z.H. Fan, D. Pan, and P. Zhou A protein tyrosine phosphatase 1B activity inhibitor from the fruiting bodies of Ganoderma lucidum (Fr.) Karst and its hypoglycemic potency on streptozotocin-induced type 2 diabetic mice J. Agric. Food Chem. 59 2011 6492 6500
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 6492-6500
    • Teng, B.S.1    Wang, C.D.2    Yang, H.J.3    Wu, J.S.4    Zhang, D.5    Zheng, M.6    Fan, Z.H.7    Pan, D.8    Zhou, P.9
  • 85
    • 84859506207 scopus 로고    scopus 로고
    • Hypoglycemic effect and mechanism of a proteoglycan from Ganoderma lucidum on streptozotocin-induced type 2 diabetic rats
    • B.S. Teng, C.D. Wang, D. Zhang, J.S. Wu, D. Pan, L.F. Pan, H.J. Yang, and P. Zhou Hypoglycemic effect and mechanism of a proteoglycan from Ganoderma lucidum on streptozotocin-induced type 2 diabetic rats Eur. Rev. Med. Pharmacol. Sci. 16 2012 166 175
    • (2012) Eur. Rev. Med. Pharmacol. Sci. , vol.16 , pp. 166-175
    • Teng, B.S.1    Wang, C.D.2    Zhang, D.3    Wu, J.S.4    Pan, D.5    Pan, L.F.6    Yang, H.J.7    Zhou, P.8
  • 86
    • 80052858533 scopus 로고    scopus 로고
    • ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK
    • A. Thyagarajan-Sahu, B. Lane, and D. Sliva ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK BMC Complement. Altern. Med. 11 2011 74
    • (2011) BMC Complement. Altern. Med. , vol.11 , pp. 74
    • Thyagarajan-Sahu, A.1    Lane, B.2    Sliva, D.3
  • 87
    • 84867867477 scopus 로고    scopus 로고
    • The nuclear factor kappa B signaling pathway: Integrating metabolism with inflammation
    • L. Tornatore, A.K. Thotakura, J. Bennett, M. Moretti, and G. Franzoso The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation Trends Cell Biol. 22 2012 557 566
    • (2012) Trends Cell Biol. , vol.22 , pp. 557-566
    • Tornatore, L.1    Thotakura, A.K.2    Bennett, J.3    Moretti, M.4    Franzoso, G.5
  • 89
    • 84893215166 scopus 로고    scopus 로고
    • Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: Search for modulators of intracellular glucocorticoid concentrations
    • A. Vuorinen, L.G. Nashev, A. Odermatt, J.M. Rollinger, and D. Schuster Pharmacophore model refinement for 11β-hydroxysteroid dehydrogenase inhibitors: search for modulators of intracellular glucocorticoid concentrations Mol. Inf. 33 2014 15 25
    • (2014) Mol. Inf. , vol.33 , pp. 15-25
    • Vuorinen, A.1    Nashev, L.G.2    Odermatt, A.3    Rollinger, J.M.4    Schuster, D.5
  • 90
    • 84866101342 scopus 로고    scopus 로고
    • Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice
    • C.-D. Wang, B.-S. Teng, Y.-M. He, J.-S. Wu, D. Pan, L.-F. Pan, D. Zhang, Z.-H. Fan, H.-J. Yang, and P. Zhou Effect of a novel proteoglycan PTP1B inhibitor from Ganoderma lucidum on the amelioration of hyperglycaemia and dyslipidaemia in db/db mice Br. J. Nutr. 108 2012 2014 2025
    • (2012) Br. J. Nutr. , vol.108 , pp. 2014-2025
    • Wang, C.-D.1    Teng, B.-S.2    He, Y.-M.3    Wu, J.-S.4    Pan, D.5    Pan, L.-F.6    Zhang, D.7    Fan, Z.-H.8    Yang, H.-J.9    Zhou, P.10
  • 92
    • 13844320566 scopus 로고    scopus 로고
    • LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters
    • G. Wolber, and T. Langer LigandScout: 3-D pharmacophores derived from protein-bound ligands and their use as virtual screening filters J. Chem. Inf. Model. 45 2005 160 169
    • (2005) J. Chem. Inf. Model. , vol.45 , pp. 160-169
    • Wolber, G.1    Langer, T.2
  • 93
    • 84885913687 scopus 로고    scopus 로고
    • Fast analysis of triterpenoids in Ganoderma lucidum spores by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry
    • Z. Yan, B. Xia, M.H. Qiu, L.S. Ding, and H.X. Xu Fast analysis of triterpenoids in Ganoderma lucidum spores by ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry Biomed. Chromatogr. 27 2013 1560 1567
    • (2013) Biomed. Chromatogr. , vol.27 , pp. 1560-1567
    • Yan, Z.1    Xia, B.2    Qiu, M.H.3    Ding, L.S.4    Xu, H.X.5
  • 94
    • 33845965710 scopus 로고    scopus 로고
    • Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography
    • J. Zhao, X.-Q. Zhang, S.-P. Li, F.-Q. Yang, Y.-T. Wang, and W.-C. Ye Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography J. Sep. Sci. 29 2006 2609 2615
    • (2006) J. Sep. Sci. , vol.29 , pp. 2609-2615
    • Zhao, J.1    Zhang, X.-Q.2    Li, S.-P.3    Yang, F.-Q.4    Wang, Y.-T.5    Ye, W.-C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.