Pharmacophore modeling and parallel screening for PPAR ligands

Journal of Computer-Aided Molecular Design

Volumn 21, Issue 10-11, 2007, Pages 575-590

  Markt, Patrick ^a   Schuster, Daniela ^a,b   Kirchmair, Johannes ^a,b   Laggner, Christian ^a   Langer, Thierry ^a,b  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b Inte:Ligand Software Entwicklungs und Consulting GmbH   (Austria)

Author keywords

Activity profiling; Ilib:diverse; LigandScout; Parallel screening; Pharmacophore modelling; PPAR; Target fishing; Virtual screening

Indexed keywords

DATABASE SYSTEMS; PHARMACODYNAMICS;

ACTIVITY PROFILING; ILIB:DIVERSE; LIGANDSCOUT; MODEL SCREENING; PARALLEL SCREENING; PHARMACOPHORE MODELS; PPAR; STRUCTURE-BASED; TARGET FISHING; VIRTUAL SCREENING;

LIGANDS;

5 (2,4 DIOXO 5 THIAZOLIDINYLMETHYL) 2 METHOXY N [4 (TRIFLUOROMETHYL)BENZYL]BENZAMIDE; BRL 48482; BVT 13; CLX M 1; FARGLITAZAR; GW 2331; GW 2433; GW 409544; LIGAND; NNC 61 4424; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PIOGLITAZONE; RAGAGLITAZAR; TESAGLITAZAR; TROGLITAZONE; UNCLASSIFIED DRUG;

ARTICLE; COMPUTER AIDED DESIGN; COMPUTER MODEL; CONTROLLED STUDY; DATA BASE; DRUG SCREENING; DRUG STRUCTURE; DRUG TARGETING; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN TARGETING; VALIDATION PROCESS;

EID: 36949030830     PISSN: 0920654X     EISSN: 15734951     Source Type: Journal    
DOI: 10.1007/s10822-007-9140-0     Document Type: Article

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