Attenuation of aldose reductase gene suppresses high-glucose-induced apoptosis and oxidative stress in rat lens epithelial cells

Diabetes Research and Clinical Practice

Volumn 82, Issue 1, 2008, Pages 18-24

  Nambu, Hirotaka ^a   Kubo, Eri ^a   Takamura, Yoshihiro ^a   Tsuzuki, Shosai ^a   Tamura, Miyuki ^b   Akagi, Yoshio ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

Author keywords

Aldose reductase; Aldose reductase inhibitor; Rat lens epithelial cell; Small interference RNA; Sugar cataract

Indexed keywords

ALDEHYDE REDUCTASE; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CATARACTOGENESIS; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; GENE REPRESSION; GLUCOSE ASSAY; LENS EPITHELIUM; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; RISK FACTOR; RNA INTERFERENCE; RNA SEQUENCE;

ALDEHYDE REDUCTASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CELL SURVIVAL; EPITHELIAL CELLS; GLUCOSE; IN SITU NICK-END LABELING; LENS, CRYSTALLINE; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE;

EID: 52949116851     PISSN: 01688227     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.diabres.2008.03.023     Document Type: Article

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