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Volumn 308, Issue 9, 2015, Pages E699-E712

Dysregulation of skeletal muscle protein metabolism by alcohol

Author keywords

Alcohol use disorder; Ethanol; Protein synthesis; Proteolysis; Skeletal muscle

Indexed keywords

ALCOHOL; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MUSCLE PROTEIN; PROTEASOME; REACTIVE OXYGEN METABOLITE; UBIQUITIN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; TARGET OF RAPAMYCIN KINASE;

EID: 84929688466     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00006.2015     Document Type: Review
Times cited : (102)

References (162)
  • 2
    • 84861843696 scopus 로고    scopus 로고
    • A mechanistic overview of translation initiation in eukaryotes
    • Aitken CE, Lorsch JR. A mechanistic overview of translation initiation in eukaryotes. Nat Struct Mol Biol 19: 568–576, 2012.
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 568-576
    • Aitken, C.E.1    Lorsch, J.R.2
  • 3
    • 84895488953 scopus 로고    scopus 로고
    • Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression
    • Baehr LM, Tunzi M, Bodine SC. Muscle hypertrophy is associated with increases in proteasome activity that is independent of MuRF1 and MAFbx expression. Front Physiol 5: 69, 2014.
    • (2014) Front Physiol , vol.5
    • Baehr, L.M.1    Tunzi, M.2    Bodine, S.C.3
  • 5
    • 84903158167 scopus 로고    scopus 로고
    • Regulation of mTORC1 by amino acids
    • Bar-Peled L, Sabatini DM. Regulation of mTORC1 by amino acids. Trends Cell Biol 24: 400–406, 2014.
    • (2014) Trends Cell Biol , vol.24 , pp. 400-406
    • Bar-Peled, L.1    Sabatini, D.M.2
  • 6
    • 84885177513 scopus 로고    scopus 로고
    • Disuse-induced muscle wasting
    • Bodine SC. Disuse-induced muscle wasting. Int J Biochem Cell Biol 45: 2200–2208, 2013.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 2200-2208
    • Bodine, S.C.1
  • 9
    • 0026101515 scopus 로고
    • Maintenance of structural and functional characteristics of skeletalmuscle mitochondria and sarcoplasmic-reticular membranes after chronic ethanol treatment
    • Cardellach F, Taraschi TF, Ellingson JS, Stubbs CD, Rubin E, Hoek JB. Maintenance of structural and functional characteristics of skeletalmuscle mitochondria and sarcoplasmic-reticular membranes after chronic ethanol treatment. Biochem J 274: 565–573, 1991.
    • (1991) Biochem J , vol.274 , pp. 565-573
    • Cardellach, F.1    Taraschi, T.F.2    Ellingson, J.S.3    Stubbs, C.D.4    Rubin, E.5    Hoek, J.B.6
  • 10
    • 80051603370 scopus 로고    scopus 로고
    • Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats
    • Clary CR, Guidot DM, Bratina MA, Otis JS. Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats. AIDS Res Ther 8: 30, 2011.
    • (2011) AIDS Res Ther , vol.8
    • Clary, C.R.1    Guidot, D.M.2    Bratina, M.A.3    Otis, J.S.4
  • 11
    • 84899078762 scopus 로고    scopus 로고
    • Skeletal muscle function deficit: A new terminology to embrace the evolving concepts of sarcopenia and agerelated muscle dysfunction
    • Correa-de-Araujo R, Hadley E. Skeletal muscle function deficit: a new terminology to embrace the evolving concepts of sarcopenia and agerelated muscle dysfunction. J Gerontol A Biol Sci Med Sci 69: 591–594, 2014.
    • (2014) J Gerontol a Biol Sci Med Sci , vol.69 , pp. 591-594
    • Correa-De-Araujo, R.1    Hadley, E.2
  • 12
    • 58249140206 scopus 로고    scopus 로고
    • Binge drinking in young adults: Data, definitions, and determinants
    • Courtney KE, Polich J. Binge drinking in young adults: Data, definitions, and determinants. Psychol Bull 135: 142–156, 2009.
    • (2009) Psychol Bull , vol.135 , pp. 142-156
    • Courtney, K.E.1    Polich, J.2
  • 13
    • 0027143612 scopus 로고
    • Alcohol consumption in rats potentiates the deleterious effect of gram-negative sepsis on hepatic hyaluronan uptake
    • Deaciuc IV, McDonough KH, Bagby GJ, Spitzer JJ. Alcohol consumption in rats potentiates the deleterious effect of gram-negative sepsis on hepatic hyaluronan uptake. Alcohol Clin Exp Res 17: 1002–1008, 1993.
    • (1993) Alcohol Clin Exp Res , vol.17 , pp. 1002-1008
    • Deaciuc, I.V.1    McDonough, K.H.2    Bagby, G.J.3    Spitzer, J.J.4
  • 15
    • 0023710697 scopus 로고
    • Nutritional status in alcoholics with and without chronic skeletal muscle myopathy
    • Duane P, Peters TJ. Nutritional status in alcoholics with and without chronic skeletal muscle myopathy. Alcohol Alcohol 23: 271–277, 1988.
    • (1988) Alcohol Alcohol , vol.23 , pp. 271-277
    • Duane, P.1    Peters, T.J.2
  • 16
    • 84899525169 scopus 로고    scopus 로고
    • Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling
    • Eisner V, Lenaers G, Hajnoczky G. Mitochondrial fusion is frequent in skeletal muscle and supports excitation-contraction coupling. J Cell Biol 205: 179–195, 2014.
    • (2014) J Cell Biol , vol.205 , pp. 179-195
    • Eisner, V.1    Lenaers, G.2    Hajnoczky, G.3
  • 18
    • 0021691716 scopus 로고
    • Ethanol clearance in nine inbred rat strains
    • Erickson CK. Ethanol clearance in nine inbred rat strains. Alcohol Clin Exp Res 8: 491–494, 1984.
    • (1984) Alcohol Clin Exp Res , vol.8 , pp. 491-494
    • Erickson, C.K.1
  • 20
    • 0027449323 scopus 로고
    • Relationship between ethanol-related diseases and nutritional status in chronically alcoholic men
    • Estruch R, Nicolás JM, Villegas E, Junqué A, Urbano-Márquez A. Relationship between ethanol-related diseases and nutritional status in chronically alcoholic men. Alcohol Alcohol 28: 543–550, 1993.
    • (1993) Alcohol Alcohol , vol.28 , pp. 543-550
    • Estruch, R.1    Nicolás, J.M.2    Villegas, E.3    Junqué, A.4    Urbano-Márquez, A.5
  • 23
    • 0030495865 scopus 로고    scopus 로고
    • Quantitative measure of muscle strength and size in chronic alcoholism: An early indication of tissue damage
    • Freilich R, Kirsner R, Whelan G, Chmiel R, Byrne E. Quantitative measure of muscle strength and size in chronic alcoholism: an early indication of tissue damage. Drug Alcohol Rev 15: 277–287, 1996.
    • (1996) Drug Alcohol Rev , vol.15 , pp. 277-287
    • Freilich, R.1    Kirsner, R.2    Whelan, G.3    Chmiel, R.4    Byrne, E.5
  • 24
    • 79955133814 scopus 로고    scopus 로고
    • MTOR signaling in skeletal muscle during sepsis and inflammation: Where does it all go wrong?
    • Frost RA, Lang CH. mTOR signaling in skeletal muscle during sepsis and inflammation: where does it all go wrong? Physiology (Bethesda) 26: 83–96, 2011.
    • (2011) Physiology (Bethesda) , vol.26 , pp. 83-96
    • Frost, R.A.1    Lang, C.H.2
  • 25
    • 84861975535 scopus 로고    scopus 로고
    • Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle
    • vi
    • Frost RA, Lang CH. Multifaceted role of insulin-like growth factors and mammalian target of rapamycin in skeletal muscle. Endocrinol Metab Clin North Am 41: 297–322, vi, 2012.
    • (2012) Endocrinol Metab Clin North Am , vol.41 , pp. 297-322
    • Frost, R.A.1    Lang, C.H.2
  • 26
    • 34447644976 scopus 로고
    • Protein kinase B/Akt: A nexus of growth factor and cytokine signaling in determining muscle mass
    • 2007
    • Frost RA, Lang CH. Protein kinase B/Akt: a nexus of growth factor and cytokine signaling in determining muscle mass. J Appl Physiol (1985) 103: 378–387, 2007.
    • (1985) J Appl Physiol , vol.103 , pp. 378
    • Frost, R.A.1    Lang, C.H.2
  • 27
    • 45949110040 scopus 로고    scopus 로고
    • Regulation of muscle growth by pathogen-associated molecules
    • Frost RA, Lang CH. Regulation of muscle growth by pathogen-associated molecules. J Anim Sci 86: E84–E93, 2008.
    • (2008) J Anim Sci , vol.86 , pp. E84-E93
    • Frost, R.A.1    Lang, C.H.2
  • 28
    • 23044493449 scopus 로고    scopus 로고
    • Temporal differences in the ability of ethanol to modulate endotoxin-induced increases in inflammatory cytokines in muscle under in vivo conditions
    • Frost RA, Nystrom G, Burrows PV, Lang CH. Temporal differences in the ability of ethanol to modulate endotoxin-induced increases in inflammatory cytokines in muscle under in vivo conditions. Alcohol Clin Exp Res 29: 1247–1256, 2005.
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 1247-1256
    • Frost, R.A.1    Nystrom, G.2    Burrows, P.V.3    Lang, C.H.4
  • 29
  • 30
    • 84899723616 scopus 로고    scopus 로고
    • New roles for Smad signaling and phosphatidic acid in the regulation of skeletal muscle mass
    • Goodman CA, Hornberger TA. New roles for Smad signaling and phosphatidic acid in the regulation of skeletal muscle mass. F1000Prime Rep 6: 20, 2014.
    • (2014) F1000prime Rep , vol.6
    • Goodman, C.A.1    Hornberger, T.A.2
  • 31
    • 84914108445 scopus 로고    scopus 로고
    • Influence of mTOR in energy and metabolic homeostasis
    • Haissaguerre M, Saucisse N, Cota D. Influence of mTOR in energy and metabolic homeostasis. Mol Cell Endocrinol 397: 67–77, 2014.
    • (2014) Mol Cell Endocrinol , vol.397 , pp. 67-77
    • Haissaguerre, M.1    Saucisse, N.2    Cota, D.3
  • 32
    • 77953577017 scopus 로고    scopus 로고
    • Wyttenbach A. MTOR’s role in ageing: Protein synthesis or autophagy?
    • Hands SL, Proud CG, Wyttenbach A. mTOR’s role in ageing: protein synthesis or autophagy? Aging (Albany NY) 1: 586–597, 2009.
    • (2009) Aging (Albany NY) , vol.1 , pp. 586-597
    • Hands, S.L.1    Proud, C.G.2
  • 34
    • 34347394132 scopus 로고    scopus 로고
    • Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions
    • Hasin DS, Stinson FS, Ogburn E, Grant BF. Prevalence, correlates, disability, and comorbidity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 64: 830–842, 2007.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 830-842
    • Hasin, D.S.1    Stinson, F.S.2    Ogburn, E.3    Grant, B.F.4
  • 36
    • 0036083422 scopus 로고    scopus 로고
    • Alcohol and mitochondria: A dysfunctional relationship
    • Hoek JB, Cahill A, Pastorino JG. Alcohol and mitochondria: a dysfunctional relationship. Gastroenterology 122: 2049–2063, 2002.
    • (2002) Gastroenterology , vol.122 , pp. 2049-2063
    • Hoek, J.B.1    Cahill, A.2    Pastorino, J.G.3
  • 38
    • 85017304237 scopus 로고    scopus 로고
    • Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1- sestrin3-AMPK signaling cascade in myocytes
    • Hong-Brown LQ, Brown C, Navaratnarajah M, Lang CH. Adamts1 mediates ethanol-induced alterations in collagen and elastin via a FoxO1- sestrin3-AMPK signaling cascade in myocytes. J Cell Biochem 116: 91–101, 2015.
    • (2015) J Cell Biochem , vol.116 , pp. 91-101
    • Hong-Brown, L.Q.1    Brown, C.2    Navaratnarajah, M.3    Lang, C.H.4
  • 39
    • 33746354908 scopus 로고    scopus 로고
    • Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes
    • Hong-Brown LQ, Brown CR, Huber DS, Lang CH. Alcohol and indinavir adversely affect protein synthesis and phosphorylation of MAPK and mTOR signaling pathways in C2C12 myocytes. Alcohol Clin Exp Res 30: 1297–1307, 2006.
    • (2006) Alcohol Clin Exp Res , vol.30 , pp. 1297-1307
    • Hong-Brown, L.Q.1    Brown, C.R.2    Huber, D.S.3    Lang, C.H.4
  • 40
    • 54849427710 scopus 로고    scopus 로고
    • Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase
    • Hong-Brown LQ, Brown CR, Huber DS, Lang CH. Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase. J Cell Biochem 105: 814–823, 2008.
    • (2008) J Cell Biochem , vol.105 , pp. 814-823
    • Hong-Brown, L.Q.1    Brown, C.R.2    Huber, D.S.3    Lang, C.H.4
  • 41
    • 84861172622 scopus 로고    scopus 로고
    • Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine
    • Hong-Brown LQ, Brown CR, Kazi AA, Navaratnarajah M, Lang CH. Rag GTPases and AMPK/TSC2/Rheb mediate the differential regulation of mTORC1 signaling in response to alcohol and leucine. Am J Physiol Cell Physiol 302: C1557–C1565, 2012.
    • (2012) Am J Physiol Cell Physiol , vol.302 , pp. C1557-C1565
    • Hong-Brown, L.Q.1    Brown, C.R.2    Kazi, A.A.3    Navaratnarajah, M.4    Lang, C.H.5
  • 43
    • 84886410024 scopus 로고    scopus 로고
    • Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes
    • Hong-Brown LQ, Brown CR, Navaratnarajah M, Lang CH. Activation of AMPK/TSC2/PLD by alcohol regulates mTORC1 and mTORC2 assembly in C2C12 myocytes. Alcohol Clin Exp Res 37: 1849–1861, 2013.
    • (2013) Alcohol Clin Exp Res , vol.37 , pp. 1849-1861
    • Hong-Brown, L.Q.1    Brown, C.R.2    Navaratnarajah, M.3    Lang, C.H.4
  • 44
    • 0034828099 scopus 로고    scopus 로고
    • Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells
    • Hong-Brown LQ, Frost RA, Lang CH. Alcohol impairs protein synthesis and degradation in cultured skeletal muscle cells. Alcohol Clin Exp Res 25: 1373–1382, 2001.
    • (2001) Alcohol Clin Exp Res , vol.25 , pp. 1373-1382
    • Hong-Brown, L.Q.1    Frost, R.A.2    Lang, C.H.3
  • 45
    • 84886376540 scopus 로고    scopus 로고
    • Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes
    • Hong-Brown LQ, Kazi AA, Lang CH. Mechanisms mediating the effects of alcohol and HIV anti-retroviral agents on mTORC1, mTORC2 and protein synthesis in myocytes. World J Biol Chem 3: 110–120, 2012.
    • (2012) World J Biol Chem , vol.3 , pp. 110-120
    • Hong-Brown, L.Q.1    Kazi, A.A.2    Lang, C.H.3
  • 48
    • 0034959662 scopus 로고    scopus 로고
    • Reduced mitochondrial adenosine triphosphate synthesis in skeletal muscle in patients with Child-Pugh class B and C cirrhosis
    • Jacobsen EB, Hamberg O, Quistorff B, Ott P. Reduced mitochondrial adenosine triphosphate synthesis in skeletal muscle in patients with Child-Pugh class B and C cirrhosis. Hepatology 34: 7–12, 2001.
    • (2001) Hepatology , vol.34 , pp. 7-12
    • Jacobsen, E.B.1    Hamberg, O.2    Quistorff, B.3    Ott, P.4
  • 49
    • 84899518577 scopus 로고    scopus 로고
    • Alcohol consumption over time and risk of death: A systematic review and meta-analysis
    • Jayasekara H, English DR, Room R, MacInnis RJ. Alcohol consumption over time and risk of death: a systematic review and meta-analysis. Am J Epidemiol 179: 1049–1059, 2014.
    • (2014) Am J Epidemiol , vol.179 , pp. 1049-1059
    • Jayasekara, H.1    English, D.R.2    Room, R.3    Macinnis, R.J.4
  • 51
    • 0021324383 scopus 로고
    • Ethanol metabolism in women taking oral contraceptives
    • Jones MK, Jones BM. Ethanol metabolism in women taking oral contraceptives. Alcohol Clin Exp Res 8: 24–28, 1984.
    • (1984) Alcohol Clin Exp Res , vol.8 , pp. 24-28
    • Jones, M.K.1    Jones, B.M.2
  • 52
    • 34247188485 scopus 로고    scopus 로고
    • The alcoholic lung: Epidemiology, pathophysiology, and potential therapies
    • Joshi PC, Guidot DM. The alcoholic lung: epidemiology, pathophysiology, and potential therapies. Am J Physiol Lung Cell Mol Physiol 292: L813–L823, 2007.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.292 , pp. L813-L823
    • Joshi, P.C.1    Guidot, D.M.2
  • 53
    • 67651158958 scopus 로고    scopus 로고
    • Prevalence and clinical implications of interactive toxicity beliefs regarding mixing alcohol and antiretroviral therapies among people living with HIV/AIDS
    • Kalichman SC, Amaral CM, White D, Swetsze C, Pope H, Kalichman MO, Cherry C, Eaton L. Prevalence and clinical implications of interactive toxicity beliefs regarding mixing alcohol and antiretroviral therapies among people living with HIV/AIDS. AIDS Patient Care STDS 23: 449–454, 2009.
    • (2009) AIDS Patient Care STDS , vol.23 , pp. 449-454
    • Kalichman, S.C.1    Amaral, C.M.2    White, D.3    Swetsze, C.4    Pope, H.5    Kalichman, M.O.6    Cherry, C.7    Eaton, L.8
  • 54
  • 55
    • 84858323029 scopus 로고    scopus 로고
    • Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy
    • Kazi AA, Hong-Brown L, Lang SM, Lang CH. Deptor knockdown enhances mTOR Activity and protein synthesis in myocytes and ameliorates disuse muscle atrophy. Mol Med 17: 925–936, 2011.
    • (2011) Mol Med , vol.17 , pp. 925-936
    • Kazi, A.A.1    Hong-Brown, L.2    Lang, S.M.3    Lang, C.H.4
  • 56
    • 0016793618 scopus 로고
    • Effects of chronic ethanol abuse on structure and enzyme activities of skeletal muscle in man
    • Kiessling KH, Pilstrom L, Bylund AC, Piehl K, Saltin B. Effects of chronic ethanol abuse on structure and enzyme activities of skeletal muscle in man. Scand J Clin Lab Invest 35: 601–607, 1975.
    • (1975) Scand J Clin Lab Invest , vol.35 , pp. 601-607
    • Kiessling, K.H.1    Pilstrom, L.2    Bylund, A.C.3    Piehl, K.4    Saltin, B.5
  • 57
    • 31544466776 scopus 로고    scopus 로고
    • Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis
    • Kimball SR, Jefferson LS. Signaling pathways and molecular mechanisms through which branched-chain amino acids mediate translational control of protein synthesis. J Nutr 136: 227S–231S, 2006.
    • (2006) J Nutr , vol.136 , pp. 227S-231S
    • Kimball, S.R.1    Jefferson, L.S.2
  • 58
    • 0014125659 scopus 로고
    • Spectrum of myopathy associated with alcoholism. II. Light and electron microscopic observations
    • Klinkerfuss G, Bleisch V, Dioso MM, Perkoff GT. A spectrum of myopathy associated with alcoholism. II. Light and electron microscopic observations. Ann Intern Med 67: 493–510, 1967.
    • (1967) Ann Intern Med , vol.67 , pp. 493-510
    • Klinkerfuss, G.1    Bleisch, V.2    Dioso, M.M.3    Perkoff, G.4
  • 59
    • 0036148603 scopus 로고    scopus 로고
    • Effect of acute and chronic alcohol treatment and their superimposition on lysosomal, cytoplasmic, and proteosomal protease activities in rat skeletal muscle in vivo
    • Koll M, Ahmed S, Mantle D, Donohue TM, Palmer TN, Simanowski UA, Seltz HK, Peters TJ, Preedy VR. Effect of acute and chronic alcohol treatment and their superimposition on lysosomal, cytoplasmic, and proteosomal protease activities in rat skeletal muscle in vivo. Metabolism 51: 97–104, 2002.
    • (2002) Metabolism , vol.51 , pp. 97-104
    • Koll, M.1    Ahmed, S.2    Mantle, D.3    Donohue, T.M.4    Palmer, T.N.5    Simanowski, U.A.6    Seltz, H.K.7    Peters, T.J.8    Preedy, V.R.9
  • 60
    • 0344406237 scopus 로고    scopus 로고
    • Chronic alpha-tocopherol supplementation in rats does not ameliorate either chronic or acute alcohol-induced changes in muscle protein metabolism
    • Koll M, Beeso JA, Kelly FJ, Simanowski UA, Seitz HK, Peters TJ, Preedy VR. Chronic alpha-tocopherol supplementation in rats does not ameliorate either chronic or acute alcohol-induced changes in muscle protein metabolism. Clin Sci (Lond) 104: 287–294, 2003.
    • (2003) Clin Sci (Lond) , vol.104 , pp. 287-294
    • Koll, M.1    Beeso, J.A.2    Kelly, F.J.3    Simanowski, U.A.4    Seitz, H.K.5    Peters, T.J.6    Preedy, V.R.7
  • 61
    • 0034538785 scopus 로고    scopus 로고
    • Carbonyl levels in type I and II fiber-rich muscles and their response to chronic ethanol feeding in vivo and hydroxyl and superoxide radicals in vitro
    • Koo-Ng R, Falkous G, Reilly M, Peters TJ, Mantle D, Preedy VR. Carbonyl levels in type I and II fiber-rich muscles and their response to chronic ethanol feeding in vivo and hydroxyl and superoxide radicals in vitro. Alcohol Clin Exp Res 24: 1862–1868, 2000.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 1862-1868
    • Koo-Ng, R.1    Falkous, G.2    Reilly, M.3    Peters, T.J.4    Mantle, D.5    Preedy, V.R.6
  • 63
    • 0036838513 scopus 로고    scopus 로고
    • Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle
    • Kumar V, Frost RA, Lang CH. Alcohol impairs insulin and IGF-I stimulation of S6K1 but not 4E-BP1 in skeletal muscle. Am J Physiol Endocrinol Metab 283: E917–E928, 2002.
    • (2002) Am J Physiol Endocrinol Metab , vol.283 , pp. E917-E928
    • Kumar, V.1    Frost, R.A.2    Lang, C.H.3
  • 64
    • 84883813989 scopus 로고    scopus 로고
    • Cytoskeleton and regulation of mitochondrial function: The role of beta-tubulin II
    • Kuznetsov AV, Javadov S, Guzun R, Grimm M, Saks V. Cytoskeleton and regulation of mitochondrial function: the role of beta-tubulin II. Front Physiol 4: 82, 2013.
    • (2013) Front Physiol , vol.4
    • Kuznetsov, A.V.1    Javadov, S.2    Guzun, R.3    Grimm, M.4    Saks, V.5
  • 67
    • 0033672793 scopus 로고    scopus 로고
    • Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F
    • Lang CH, Frost RA, Kumar V, Vary TC. Impaired myocardial protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4F. Am J Physiol Endocrinol Metab 279: E1029–E1038, 2000.
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , pp. E1029-E1038
    • Lang, C.H.1    Frost, R.A.2    Kumar, V.3    Vary, T.C.4
  • 68
    • 0034102791 scopus 로고    scopus 로고
    • Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver
    • Lang CH, Frost RA, Kumar V, Wu D, Vary TC. Impaired protein synthesis induced by acute alcohol intoxication is associated with changes in eIF4E in muscle and eIF2B in liver. Alcohol Clin Exp Res 24: 322–331, 2000.
    • (2000) Alcohol Clin Exp Res , vol.24 , pp. 322-331
    • Lang, C.H.1    Frost, R.A.2    Kumar, V.3    Wu, D.4    Vary, T.C.5
  • 69
    • 2442658168 scopus 로고    scopus 로고
    • IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats
    • Lang CH, Frost RA, Svanberg E, Vary TC. IGF-I/IGFBP-3 ameliorates alterations in protein synthesis, eIF4E availability, and myostatin in alcohol-fed rats. Am J Physiol Endocrinol Metab 286: E916–E926, 2004.
    • (2004) Am J Physiol Endocrinol Metab , vol.286 , pp. E916-E926
    • Lang, C.H.1    Frost, R.A.2    Svanberg, E.3    Vary, T.C.4
  • 70
    • 42549141544 scopus 로고    scopus 로고
    • Acute alcohol intoxication increases REDD1 in skeletal muscle
    • Lang CH, Frost RA, Vary TC. Acute alcohol intoxication increases REDD1 in skeletal muscle. Alcohol Clin Exp Res 32: 796–805, 2008.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 796-805
    • Lang, C.H.1    Frost, R.A.2    Vary, T.C.3
  • 71
    • 34547632886 scopus 로고    scopus 로고
    • Regulation of muscle protein synthesis during sepsis and inflammation
    • Lang CH, Frost RA, Vary TC. Regulation of muscle protein synthesis during sepsis and inflammation. Am J Physiol Endocrinol Metab 293: E453–E459, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E453-E459
    • Lang, C.H.1    Frost, R.A.2    Vary, T.C.3
  • 72
    • 34447567479 scopus 로고    scopus 로고
    • Skeletal muscle protein synthesis and degradation exhibit sexual dimorphism after chronic alcohol consumption but not acute intoxication
    • Lang CH, Frost RA, Vary TC. Skeletal muscle protein synthesis and degradation exhibit sexual dimorphism after chronic alcohol consumption but not acute intoxication. Am J Physiol Endocrinol Metab 292: E1497–E1506, 2007.
    • (2007) Am J Physiol Endocrinol Metab , vol.292 , pp. E1497-E1506
    • Lang, C.H.1    Frost, R.A.2    Vary, T.C.3
  • 73
    • 33846158821 scopus 로고    scopus 로고
    • Burn-induced increase in atrogin-1 and MuRF-1 in skeletal muscle is glucocorticoid independent but downregulated by IGF-I
    • Lang CH, Huber D, Frost RA. Burn-induced increase in atrogin-1 and MuRF-1 in skeletal muscle is glucocorticoid independent but downregulated by IGF-I. Am J Physiol Regul Integr Comp Physiol 292: R328–R336, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , pp. R328-R336
    • Lang, C.H.1    Huber, D.2    Frost, R.A.3
  • 74
    • 0035025348 scopus 로고    scopus 로고
    • Alcohol myopathy: Impairment of protein synthesis and translation initiation
    • Lang CH, Kimball SR, Frost RA, Vary TC. Alcohol myopathy: impairment of protein synthesis and translation initiation. Int J Biochem Cell Biol 33: 457–473, 2001.
    • (2001) Int J Biochem Cell Biol , vol.33 , pp. 457-473
    • Lang, C.H.1    Kimball, S.R.2    Frost, R.A.3    Vary, T.C.4
  • 76
    • 77951450185 scopus 로고    scopus 로고
    • Resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase
    • Lang CH, Lynch CJ, Vary TC. Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase. J Nutr 140: 932–938, 2010.
    • (2010) J Nutr , vol.140 , pp. 932-938
    • Lang, C.H.1    Lynch, C.J.2    Vary, T.C.3    Alcohol-Induced, I.-I.4
  • 77
    • 77956679005 scopus 로고    scopus 로고
    • BCATm deficiency ameliorates endotoxin- induced decrease in muscle protein synthesis and improves survival in septic mice
    • Lang CH, Lynch CJ, Vary TC. BCATm deficiency ameliorates endotoxin- induced decrease in muscle protein synthesis and improves survival in septic mice. Am J Physiol Regul Integr Comp Physiol 299: R935–R944, 2010.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299 , pp. R935-R944
    • Lang, C.H.1    Lynch, C.J.2    Vary, T.C.3
  • 78
    • 9244257375 scopus 로고    scopus 로고
    • Alcohol intoxication impairs phosphorylation of S6K1 and S6 in skeletal muscle independently of ethanol metabolism
    • Lang CH, Pruznak AM, Deshpande N, Palopoli MM, Frost RA, Vary TC. Alcohol intoxication impairs phosphorylation of S6K1 and S6 in skeletal muscle independently of ethanol metabolism. Alcohol Clin Exp Res 28: 1758–1767, 2004.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 1758-1767
    • Lang, C.H.1    Pruznak, A.M.2    Deshpande, N.3    Palopoli, M.M.4    Frost, R.A.5    Vary, T.C.6
  • 79
    • 61849111619 scopus 로고    scopus 로고
    • Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats
    • Lang CH, Pruznak AM, Nystrom GJ, Vary TC. Alcohol-induced decrease in muscle protein synthesis associated with increased binding of mTOR and raptor: Comparable effects in young and mature rats. Nutr Metab (Lond) 6: 4, 2009.
    • (2009) Nutr Metab (Lond) , vol.6
    • Lang, C.H.1    Pruznak, A.M.2    Nystrom, G.J.3    Vary, T.C.4
  • 82
    • 84862660964 scopus 로고    scopus 로고
    • Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice
    • Lang SM, Kazi AA, Hong-Brown L, Lang CH. Delayed recovery of skeletal muscle mass following hindlimb immobilization in mTOR heterozygous mice. PLoS One 7: e38910, 2012.
    • (2012) Plos One , vol.7
    • Lang, S.M.1    Kazi, A.A.2    Hong-Brown, L.3    Lang, C.H.4
  • 83
    • 84877965001 scopus 로고    scopus 로고
    • Regulation of mTORC1 and its impact on gene expression at a glance
    • Laplante M, Sabatini DM. Regulation of mTORC1 and its impact on gene expression at a glance. J Cell Sci 126: 1713–1719, 2013.
    • (2013) J Cell Sci , vol.126 , pp. 1713-1719
    • Laplante, M.1    Sabatini, D.M.2
  • 85
    • 0024409956 scopus 로고
    • Liquid diet technique of ethanol administration: 1989 update
    • Lieber CS, DeCarli LM. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol 24: 197–211, 1989.
    • (1989) Alcohol Alcohol , vol.24 , pp. 197-211
    • Lieber, C.S.1    Decarli, L.M.2
  • 86
    • 0037528977 scopus 로고    scopus 로고
    • Blood ethanol concentration profiles: A comparison between rats and mice
    • Livy DJ, Parnell SE, West JR. Blood ethanol concentration profiles: a comparison between rats and mice. Alcohol 29: 165–171, 2003.
    • (2003) Alcohol , vol.29 , pp. 165-171
    • Livy, D.J.1    Parnell, S.E.2    West, J.R.3
  • 87
    • 0028951793 scopus 로고
    • Alcohol consumption and risk of cancer in humans: An overview
    • Longnecker MP. Alcohol consumption and risk of cancer in humans: an overview. Alcohol 12: 87–96, 1995.
    • (1995) Alcohol , vol.12 , pp. 87-96
    • Longnecker, M.P.1
  • 88
    • 84874812684 scopus 로고    scopus 로고
    • Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease
    • Maddocks M, Gao W, Higginson IJ, Wilcock A. Neuromuscular electrical stimulation for muscle weakness in adults with advanced disease. Cochrane Database Syst Rev 1: CD009419, 2013.
    • (2013) Cochrane Database Syst Rev , vol.1
    • Maddocks, M.1    Gao, W.2    Higginson, I.J.3    Wilcock, A.4
  • 90
    • 0021814114 scopus 로고
    • Alcoholic skeletal myopathy, a clinical and pathological study
    • Martin F, Ward K, Slavin G, Levi J, Peters TJ. Alcoholic skeletal myopathy, a clinical and pathological study. Q J Med 55: 233–251, 1985.
    • (1985) Q J Med , vol.55 , pp. 233-251
    • Martin, F.1    Ward, K.2    Slavin, G.3    Levi, J.4    Peters, T.J.5
  • 91
    • 0021863954 scopus 로고
    • Assessment in vitro and in vivo of muscle degradation in chronic skeletal muscle myopathy of alcoholism
    • Martin FC, Peters TJ. Assessment in vitro and in vivo of muscle degradation in chronic skeletal muscle myopathy of alcoholism. Clin Sci (Lond) 68: 693–700, 1985.
    • (1985) Clin Sci (Lond) , vol.68 , pp. 693-700
    • Martin, F.C.1    Peters, T.J.2
  • 92
    • 0025158067 scopus 로고
    • Experimental alcoholic skeletal muscle myopathy is characterised by a rapid and sustained decrease in muscle RNA content
    • Marway JS, Preedy VR, Peters TJ. Experimental alcoholic skeletal muscle myopathy is characterised by a rapid and sustained decrease in muscle RNA content. Alcohol Alcohol 25: 401–406, 1990.
    • (1990) Alcohol Alcohol , vol.25 , pp. 401-406
    • Marway, J.S.1    Preedy, V.R.2    Peters, T.J.3
  • 94
    • 84903437266 scopus 로고    scopus 로고
    • Mischel PS. MTORC2 in the center of cancer metabolic reprogramming
    • Masui K, Cavenee WK, Mischel PS. mTORC2 in the center of cancer metabolic reprogramming. Trends Endocrinol Metab 25: 364–373, 2014.
    • (2014) Trends Endocrinol Metab , vol.25 , pp. 364-373
    • Masui, K.1    Cavenee, W.K.2
  • 95
    • 84906272591 scopus 로고    scopus 로고
    • Biomedical consequences of alcohol use disorders in the HIV-infected host
    • Molina PE, Bagby GJ, Nelson S. Biomedical consequences of alcohol use disorders in the HIV-infected host. Curr HIV Res 12: 265–275, 2014.
    • (2014) Curr HIV Res , vol.12 , pp. 265-275
    • Molina, P.E.1    Bagby, G.J.2    Nelson, S.3
  • 96
    • 37349031429 scopus 로고    scopus 로고
    • Chronic alcohol accentuates simian acquired immunodeficiency syndrome-associated wasting
    • Molina PE, Lang CH, McNurlan M, Bagby GJ, Nelson S. Chronic alcohol accentuates simian acquired immunodeficiency syndrome-associated wasting. Alcohol Clin Exp Res 32: 138–147, 2008.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 138-147
    • Molina, P.E.1    Lang, C.H.2    McNurlan, M.3    Bagby, G.J.4    Nelson, S.5
  • 100
    • 0036096998 scopus 로고    scopus 로고
    • Alcohol consumption promotes body weight loss in melanoma-bearing mice
    • Nunez NP, Carter PA, Meadows GG. Alcohol consumption promotes body weight loss in melanoma-bearing mice. Alcohol Clin Exp Res 26: 617–626, 2002.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 617-626
    • Nunez, N.P.1    Carter, P.A.2    Meadows, G.G.3
  • 101
    • 78149362118 scopus 로고    scopus 로고
    • Drug harms in the UK: A multicriteria decision analysis
    • Nutt DJ, King LA, Phillips LD, and Independent Scientific Committee on D. Drug harms in the UK: a multicriteria decision analysis. Lancet 376: 1558–1565, 2010.
    • (2010) Lancet , vol.376 , pp. 1558-1565
    • Nutt, D.J.1    King, L.A.2    Phillips, L.D.3
  • 102
    • 37049021535 scopus 로고    scopus 로고
    • Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats
    • Otis JS, Brown LA, Guidot DM. Oxidant-induced atrogin-1 and transforming growth factor-beta1 precede alcohol-related myopathy in rats. Muscle Nerve 36: 842–848, 2007.
    • (2007) Muscle Nerve , vol.36 , pp. 842-848
    • Otis, J.S.1    Brown, L.A.2    Guidot, D.M.3
  • 103
    • 78149471685 scopus 로고    scopus 로고
    • Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence
    • Otis JS, Guidot DM. Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence. Alcohol Alcohol 45: 495–500, 2010.
    • (2010) Alcohol Alcohol , vol.45 , pp. 495-500
    • Otis, J.S.1    Guidot, D.M.2
  • 104
    • 68149110224 scopus 로고    scopus 로고
    • Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats
    • Otis JS, Guidot DM. Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats. Alcohol Clin Exp Res 33: 1450–1459, 2009.
    • (2009) Alcohol Clin Exp Res , vol.33 , pp. 1450-1459
    • Otis, J.S.1    Guidot, D.M.2
  • 105
    • 0026319314 scopus 로고
    • The effect of chronic alcohol ingestion on whole body and muscle protein synthesis—a stable isotope study
    • Pacy PJ, Preedy VR, Peters TJ, Read M, Halliday D. The effect of chronic alcohol ingestion on whole body and muscle protein synthesis—a stable isotope study. Alcohol Alcohol 26: 505–513, 1991.
    • (1991) Alcohol Alcohol , vol.26 , pp. 505-513
    • Pacy, P.J.1    Preedy, V.R.2    Peters, T.J.3    Read, M.4    Halliday, D.5
  • 107
    • 84883451249 scopus 로고    scopus 로고
    • Selective autophagy: Talking with the UPS
    • Park C, Cuervo AM. Selective autophagy: talking with the UPS. Cell Biochem Biophys 67: 3–13, 2013.
    • (2013) Cell Biochem Biophys , vol.67 , pp. 3-13
    • Park, C.1    Cuervo, A.M.2
  • 108
    • 84895740742 scopus 로고    scopus 로고
    • Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training
    • Parr EB, Camera DM, Areta JL, Burke LM, Phillips SM, Hawley JA, Coffey VG. Alcohol ingestion impairs maximal post-exercise rates of myofibrillar protein synthesis following a single bout of concurrent training. PLoS One 9: e88384, 2014.
    • (2014) Plos One , vol.9
    • Parr, E.B.1    Camera, D.M.2    Areta, J.L.3    Burke, L.M.4    Phillips, S.M.5    Hawley, J.A.6    Coffey, V.G.7
  • 109
  • 110
    • 0036246990 scopus 로고    scopus 로고
    • Alcoholic cardiomyopathy: Clinical characteristics, pathophysiology, incidence
    • Piano MR. Alcoholic cardiomyopathy: clinical characteristics, pathophysiology, incidence. Chest 121: 1638–1650, 2002.
    • (2002) Chest , vol.121 , pp. 1638-1650
    • Piano, M.R.1
  • 111
  • 112
    • 0024910346 scopus 로고
    • Ethanolinduced skeletal muscle myopathy: Biochemical and histochemical measurements on type I and type II fibre-rich muscles in the young rat
    • Preedy VR, Bateman CJ, Salisbury JR, Price AB, Peters TJ. Ethanolinduced skeletal muscle myopathy: biochemical and histochemical measurements on type I and type II fibre-rich muscles in the young rat. Alcohol Alcohol 24: 533–539, 1989.
    • (1989) Alcohol Alcohol , vol.24 , pp. 533-539
    • Preedy, V.R.1    Bateman, C.J.2    Salisbury, J.R.3    Price, A.B.4    Peters, T.J.5
  • 113
    • 0026774948 scopus 로고
    • The acute effects of ethanol and acetaldehyde on rates of protein synthesis in type I and type II fibre-rich skeletal muscles of the rat
    • Preedy VR, Keating JW, Peters TJ. The acute effects of ethanol and acetaldehyde on rates of protein synthesis in type I and type II fibre-rich skeletal muscles of the rat. Alcohol Alcohol 27: 241–251, 1992.
    • (1992) Alcohol Alcohol , vol.27 , pp. 241-251
    • Preedy, V.R.1    Keating, J.W.2    Peters, T.J.3
  • 114
    • 0025360297 scopus 로고
    • Alcohol and skeletal muscle disease
    • Preedy VR, Peters TJ. Alcohol and skeletal muscle disease. Alcohol Alcohol 25: 177–187, 1990.
    • (1990) Alcohol Alcohol , vol.25 , pp. 177-187
    • Preedy, V.R.1    Peters, T.J.2
  • 115
    • 0025644475 scopus 로고
    • Changes in protein, RNA and DNA and rates of protein synthesis in muscle-containing tissues of the mature rat in response to ethanol feeding: A comparative study of heart, small intestine and gastrocnemius muscle
    • Preedy VR, Peters TJ. Changes in protein, RNA and DNA and rates of protein synthesis in muscle-containing tissues of the mature rat in response to ethanol feeding: a comparative study of heart, small intestine and gastrocnemius muscle. Alcohol Alcohol 25: 489–498, 1990.
    • (1990) Alcohol Alcohol , vol.25 , pp. 489-498
    • Preedy, V.R.1    Peters, T.J.2
  • 116
    • 0023805616 scopus 로고
    • The effect of chronic ethanol ingestion on protein metabolism in type-I- and type-II-fibre-rich skeletal muscles of the rat
    • Preedy VR, Peters TJ. The effect of chronic ethanol ingestion on protein metabolism in type-I- and type-II-fibre-rich skeletal muscles of the rat. Biochem J 254: 631–639, 1988.
    • (1988) Biochem J , vol.254 , pp. 631-639
    • Preedy, V.R.1    Peters, T.J.2
  • 117
    • 84874096150 scopus 로고    scopus 로고
    • Direct central nervous system effect of alcohol alters synthesis and degradation of skeletal muscle protein
    • Pruznak AM, Nystrom J, Lang CH. Direct central nervous system effect of alcohol alters synthesis and degradation of skeletal muscle protein. Alcohol Alcohol 48: 138–145, 2013.
    • (2013) Alcohol Alcohol , vol.48 , pp. 138-145
    • Pruznak, A.M.1    Nystrom, J.2    Lang, C.H.3
  • 118
    • 84904860445 scopus 로고    scopus 로고
    • MTOR and lysosome regulation
    • Puertollano R. mTOR and lysosome regulation. F1000Prime Rep 6: 52, 2014.
    • (2014) F1000prime Rep , vol.6
    • Puertollano, R.1
  • 119
    • 33645968395 scopus 로고    scopus 로고
    • Mechanisms of alcohol-induced hepatic fibrosis: A summary of the Ron Thurman Symposium
    • Purohit V, Brenner DA. Mechanisms of alcohol-induced hepatic fibrosis: a summary of the Ron Thurman Symposium. Hepatology 43: 872–878, 2006.
    • (2006) Hepatology , vol.43 , pp. 872-878
    • Purohit, V.1    Brenner, D.A.2
  • 121
    • 0034672446 scopus 로고    scopus 로고
    • Comparative effects of acute ethanol dosage on liver and muscle protein metabolism
    • Reilly ME, Mantle D, Salisbury J, Peters TJ, Preedy VR. Comparative effects of acute ethanol dosage on liver and muscle protein metabolism. Biochem Pharmacol 60: 1773–1785, 2000.
    • (2000) Biochem Pharmacol , vol.60 , pp. 1773-1785
    • Reilly, M.E.1    Mantle, D.2    Salisbury, J.3    Peters, T.J.4    Preedy, V.R.5
  • 123
    • 84903723290 scopus 로고    scopus 로고
    • Bioenergetics and mitochondrial dysfunction in aging: Recent insights for a therapeutical approach
    • Romano AD, Greco E, Vendemiale G, Serviddio G. Bioenergetics and mitochondrial dysfunction in aging: recent insights for a therapeutical approach. Curr Pharm Des 20: 2978–2992, 2014.
    • (2014) Curr Pharm Des , vol.20 , pp. 2978-2992
    • Romano, A.D.1    Greco, E.2    Vendemiale, G.3    Serviddio, G.4
  • 125
    • 77951768486 scopus 로고    scopus 로고
    • Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
    • Sancak Y, Bar-Peled L, Zoncu R, Markhard AL, Nada S, Sabatini DM. Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids. Cell 141: 290–303, 2010.
    • (2010) Cell , vol.141 , pp. 290-303
    • Sancak, Y.1    Bar-Peled, L.2    Zoncu, R.3    Markhard, A.L.4    Nada, S.5    Sabatini, D.M.6
  • 126
    • 84885174647 scopus 로고    scopus 로고
    • Protein breakdown in muscle wasting: Role of autophagylysosome and ubiquitin-proteasome
    • Sandri M. Protein breakdown in muscle wasting: role of autophagylysosome and ubiquitin-proteasome. Int J Biochem Cell Biol 45: 2121–2129, 2013.
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 2121-2129
    • Sandri, M.1
  • 127
    • 84890283002 scopus 로고    scopus 로고
    • Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies
    • Sandri M, Coletto L, Grumati P, Bonaldo P. Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies. J Cell Sci 126: 5325–5333, 2013.
    • (2013) J Cell Sci , vol.126 , pp. 5325-5333
    • Sandri, M.1    Coletto, L.2    Grumati, P.3    Bonaldo, P.4
  • 129
    • 0033679673 scopus 로고    scopus 로고
    • 4E-BP1 and S6K1: Translational integration sites for nutritional and hormonal information in muscle
    • Shah OJ, Anthony JC, Kimball SR, Jefferson LS. 4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle. Am J Physiol Endocrinol Metab 279: E715–E729, 2000.
    • (2000) Am J Physiol Endocrinol Metab , vol.279 , pp. E715-E729
    • Shah, O.J.1    Anthony, J.C.2    Kimball, S.R.3    Jefferson, L.S.4
  • 130
    • 34548251464 scopus 로고    scopus 로고
    • Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle
    • She P, Reid TM, Bronson SK, Vary TC, Hajnal A, Lynch CJ, Hutson SM. Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle. Cell Metab 6: 181–194, 2007.
    • (2007) Cell Metab , vol.6 , pp. 181-194
    • She, P.1    Reid, T.M.2    Bronson, S.K.3    Vary, T.C.4    Hajnal, A.5    Lynch, C.J.6    Hutson, S.M.7
  • 133
  • 135
    • 77950900079 scopus 로고    scopus 로고
    • Fingar DC. MTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action
    • Soliman GA, Acosta-Jaquez HA, Dunlop EA, Ekim B, Maj NE, Tee AR, Fingar DC. mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action. J Biol Chem 285: 7866–7879, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 7866-7879
    • Soliman, G.A.1    Acosta-Jaquez, H.A.2    Dunlop, E.A.3    Ekim, B.4    Maj, N.E.5    Tee, A.R.6
  • 136
    • 0015517986 scopus 로고
    • Ethanol produces muscle damage in human volunteers
    • Song SK, Rubin E. Ethanol produces muscle damage in human volunteers. Science 175: 327–328, 1972.
    • (1972) Science , vol.175 , pp. 327-328
    • Song, S.K.1    Rubin, E.2
  • 137
    • 0024593732 scopus 로고
    • Diminished insulin-like growth factor-1 levels after chronic ethanol: Relationship to pulsatile growth hormone release
    • Sonntag WE, Boyd RL. Diminished insulin-like growth factor-1 levels after chronic ethanol: relationship to pulsatile growth hormone release. Alcohol Clin Exp Res 13: 3–7, 1989.
    • (1989) Alcohol Clin Exp Res , vol.13 , pp. 3-7
    • Sonntag, W.E.1    Boyd, R.L.2
  • 138
    • 84866704795 scopus 로고    scopus 로고
    • Regulation and physiological roles of the calpain system in muscular disorders
    • Sorimachi H, Ono Y. Regulation and physiological roles of the calpain system in muscular disorders. Cardiovasc Res 96: 11–22, 2012.
    • (2012) Cardiovasc Res , vol.96 , pp. 11-22
    • Sorimachi, H.1    Ono, Y.2
  • 139
    • 37849186260 scopus 로고    scopus 로고
    • Alcohol use among older adults
    • Sorocco KH, Ferrell SW. Alcohol use among older adults. J Gen Psychol 133: 453–467, 2006.
    • (2006) J Gen Psychol , vol.133 , pp. 453-467
    • Sorocco, K.H.1    Ferrell, S.W.2
  • 140
    • 84911935474 scopus 로고
    • Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction
    • 2014
    • Steiner JL, Lang CH. Alcohol impairs skeletal muscle protein synthesis and mTOR signaling in a time-dependent manner following electrically stimulated muscle contraction. J Appl Physiol (1985) 117: 1170–1179, 2014.
    • (1985) J Appl Physiol , vol.117 , pp. 1170-1179
    • Steiner, J.L.1    Lang, C.H.2
  • 141
    • 84921458936 scopus 로고    scopus 로고
    • Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction
    • Steiner JL, Lang CH. Alcohol intoxication following muscle contraction in mice decreases muscle protein synthesis but not mTOR signal transduction. Alcohol Clin Exp Res 39: 1–10, 2015.
    • (2015) Alcohol Clin Exp Res , vol.39 , pp. 1-10
    • Steiner, J.L.1    Lang, C.H.2
  • 142
    • 85006172606 scopus 로고    scopus 로고
    • Moderate alcohol consumption does not impair overload-induced muscle hypertrophy and protein synthesis
    • Mar, . pii:
    • Steiner JL, Lang CH. Moderate alcohol consumption does not impair overload-induced muscle hypertrophy and protein synthesis. Physiol Rep. 2015 Mar 3(3). pii: e12333. doi: 10.14814/phy2.12333.
    • (2015) Physiol Rep , vol.3 , Issue.3
    • Steiner, J.L.1    Lang, C.H.2
  • 145
    • 0035259388 scopus 로고    scopus 로고
    • Loss of skeletal muscle in cancer: Biochemical mechanisms
    • Tisdale MJ. Loss of skeletal muscle in cancer: biochemical mechanisms. Front Biosci 6: D164–D174, 2001.
    • (2001) Front Biosci , vol.6 , pp. D164-D174
    • Tisdale, M.J.1
  • 147
    • 0023387058 scopus 로고
    • Chronic alcoholic proximal wasting: Physiological, morphological and biochemical studies in skeletal muscle
    • Trounce I, Byrne E, Dennett X, Santamaria J, Doery J, Peppard R. Chronic alcoholic proximal wasting: physiological, morphological and biochemical studies in skeletal muscle. Aust NZ J Med 17: 413–419, 1987.
    • (1987) Aust NZ J Med , vol.17 , pp. 413-419
    • Trounce, I.1    Byrne, E.2    Dennett, X.3    Santamaria, J.4    Doery, J.5    Peppard, R.6
  • 150
    • 10044267663 scopus 로고    scopus 로고
    • Effects of alcohol on skeletal and cardiac muscle
    • Urbano-Marquez A, Fernandez-Sola J. Effects of alcohol on skeletal and cardiac muscle. Muscle Nerve 30: 689–707, 2004.
    • (2004) Muscle Nerve , vol.30 , pp. 689-707
    • Urbano-Marquez, A.1    Fernandez-Sola, J.2
  • 151
    • 37348998877 scopus 로고    scopus 로고
    • Alcohol accelerates loss of muscle and impairs recovery of muscle mass resulting from disuse atrophy
    • Vargas R, Lang CH. Alcohol accelerates loss of muscle and impairs recovery of muscle mass resulting from disuse atrophy. Alcohol Clin Exp Res 32: 128–137, 2008.
    • (2008) Alcohol Clin Exp Res , vol.32 , pp. 128-137
    • Vargas, R.1    Lang, C.H.2
  • 152
    • 47549118670 scopus 로고    scopus 로고
    • Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle
    • Vary TC, Frost RA, Lang CH. Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle. Am J Physiol Regul Integr Comp Physiol 294: R1777–R1789, 2008.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294 , pp. R1777-R1789
    • Vary, T.C.1    Frost, R.A.2    Lang, C.H.3
  • 153
    • 0034829027 scopus 로고    scopus 로고
    • Effects of chronic alcohol consumption on regulation of myocardial protein synthesis
    • Vary TC, Lynch CJ, Lang CH. Effects of chronic alcohol consumption on regulation of myocardial protein synthesis. Am J Physiol Heart Circ Physiol 281: H1242–H1251, 2001.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , pp. H1242-H1251
    • Vary, T.C.1    Lynch, C.J.2    Lang, C.H.3
  • 154
    • 12244288362 scopus 로고    scopus 로고
    • Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver
    • Vary TC, Nairn AC, Deiter G, Lang CH. Differential effects of alcohol consumption on eukaryotic elongation factors in heart, skeletal muscle, and liver. Alcohol Clin Exp Res 26: 1794–1802, 2002.
    • (2002) Alcohol Clin Exp Res , vol.26 , pp. 1794-1802
    • Vary, T.C.1    Nairn, A.C.2    Deiter, G.3    Lang, C.H.4
  • 155
    • 1942454745 scopus 로고    scopus 로고
    • Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol
    • Vary TC, Nairn AC, Lang CH. Restoration of protein synthesis in heart and skeletal muscle after withdrawal of alcohol. Alcohol Clin Exp Res 28: 517–525, 2004.
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 517-525
    • Vary, T.C.1    Nairn, A.C.2    Lang, C.H.3
  • 157
    • 33749431713 scopus 로고    scopus 로고
    • The mTOR pathway in the control of protein synthesis
    • Wang X, Proud CG. The mTOR pathway in the control of protein synthesis. Physiology (Bethesda) 21: 362–369, 2006.
    • (2006) Physiology (Bethesda) , vol.21 , pp. 362-369
    • Wang, X.1    Proud, C.G.2
  • 158
    • 0026470686 scopus 로고
    • The antioxidant status of patients with either alcohol-induced liver damage or myopathy
    • Ward RJ, Peters TJ. The antioxidant status of patients with either alcohol-induced liver damage or myopathy. Alcohol Alcohol 27: 359–365, 1992.
    • (1992) Alcohol Alcohol , vol.27 , pp. 359-365
    • Ward, R.J.1    Peters, T.J.2
  • 159
    • 64749116516 scopus 로고    scopus 로고
    • Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice
    • Welle S, Burgess K, Mehta S. Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice. Am J Physiol Endocrinol Metab 296: E567–E572, 2009.
    • (2009) Am J Physiol Endocrinol Metab , vol.296 , pp. E567-E572
    • Welle, S.1    Burgess, K.2    Mehta, S.3
  • 160
    • 0030330401 scopus 로고    scopus 로고
    • Effect of chronic alcohol intake on energy metabolism in human muscle
    • Yazaki K, Haida M, Kurita D, Shinohara Y. Effect of chronic alcohol intake on energy metabolism in human muscle. Alcohol Clin Exp Res 20: 360A–362A, 1996.
    • (1996) Alcohol Clin Exp Res , vol.20 , pp. 360A-362A
    • Yazaki, K.1    Haida, M.2    Kurita, D.3    Shinohara, Y.4
  • 162
    • 84910145403 scopus 로고    scopus 로고
    • Current models of mammalian target of rapamycin complex 1 (MTORC1) activation by growth factors and amino acids
    • Zheng X, Liang Y, He Q, Yao R, Bao W, Bao L, Wang Y, Wang Z. Current models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids. Int J Mol Sci 15: 20753–20769, 2014.
    • (2014) Int J Mol Sci , vol.15 , pp. 20753-20769
    • Zheng, X.1    Liang, Y.2    He, Q.3    Yao, R.4    Bao, W.5    Bao, L.6    Wang, Y.7    Wang, Z.8


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