Acute alcohol intoxication increases atrogin-1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 294, Issue 6, 2008, Pages

  Vary, Thomas C ^a   Frost, Robert A ^a   Lang, Charles H ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

3 methylhistidine; Glucocorticoid; IGF I; Protein breakdown; Protein degradation; Ubiquitin proteasome

Indexed keywords

3 METHYLHISTIDINE; ALCOHOL; ATROGIN 1; CORTICOSTERONE; DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID ANTAGONIST; MESSENGER RNA; MIFEPRISTONE; MUSCLE RING FINGER 1 PROTEIN; SOMATOMEDIN C; TYROSINE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CENTRAL DEPRESSANT AGENT; FBXO32 PROTEIN, RAT; MUSCLE PROTEIN; POLYUBIQUITIN; RNF28 PROTEIN, RAT; UBIQUITIN PROTEIN LIGASE;

ALCOHOL ABUSE; ALCOHOL INTOXICATION; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; FEMALE; GASTROCNEMIUS MUSCLE; GENE EXPRESSION; HINDLIMB; MALE; MOUSE; MUSCLE CELL; NONHUMAN; NUTRITIONAL STATUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; RAT; SEX DIFFERENCE; SKELETAL MUSCLE; SOLEUS MUSCLE; ANIMAL; DRINKING BEHAVIOR; DRUG EFFECT; FAST MUSCLE FIBER; METABOLISM; PROTEIN DENATURATION; SPRAGUE DAWLEY RAT;

ALCOHOL DRINKING; ALCOHOLIC INTOXICATION; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; ETHANOL; GLUCOCORTICOIDS; INSULIN-LIKE GROWTH FACTOR I; MALE; MUSCLE FIBERS, FAST-TWITCH; MUSCLE PROTEINS; MUSCLE, SKELETAL; POLYUBIQUITIN; PROTEIN DENATURATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN-PROTEIN LIGASES;

EID: 47549118670     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00056.2008     Document Type: Article

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