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Volumn 27, Issue 6, 2015, Pages 750-763

Irritable bowel syndrome: An integrated explanatory model for clinical practice

Author keywords

Explanations; Explanatory models; Irritable bowel syndrome; Mechanisms

Indexed keywords

SEROTONIN; SEROTONIN 3 RECEPTOR;

EID: 84929655256     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12524     Document Type: Review
Times cited : (25)

References (130)
  • 1
    • 77950520756 scopus 로고    scopus 로고
    • Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts
    • Spiegel BM, Farid M, Esrailian E, Talley J, Chang L. Is irritable bowel syndrome a diagnosis of exclusion?: a survey of primary care providers, gastroenterologists, and IBS experts. Am J Gastroenterol 2010; 105: 848-58.
    • (2010) Am J Gastroenterol , vol.105 , pp. 848-858
    • Spiegel, B.M.1    Farid, M.2    Esrailian, E.3    Talley, J.4    Chang, L.5
  • 2
    • 59849097663 scopus 로고    scopus 로고
    • GPs' explanatory models for irritable bowel syndrome: a mismatch with patient models?
    • Casiday RE, Hungin AP, Cornford CS, de Wit NJ, Blell MT. GPs' explanatory models for irritable bowel syndrome: a mismatch with patient models? Fam Pract 2009; 26: 34-9.
    • (2009) Fam Pract , vol.26 , pp. 34-39
    • Casiday, R.E.1    Hungin, A.P.2    Cornford, C.S.3    de Wit, N.J.4    Blell, M.T.5
  • 5
    • 59849115010 scopus 로고    scopus 로고
    • Patients' explanatory models for irritable bowel syndrome: symptoms and treatment more important than explaining aetiology
    • Casiday RE, Hungin AP, Cornford CS, de Wit NJ, Blell MT. Patients' explanatory models for irritable bowel syndrome: symptoms and treatment more important than explaining aetiology. Fam Pract 2009; 26: 40-7.
    • (2009) Fam Pract , vol.26 , pp. 40-47
    • Casiday, R.E.1    Hungin, A.P.2    Cornford, C.S.3    de Wit, N.J.4    Blell, M.T.5
  • 6
    • 84869422258 scopus 로고    scopus 로고
    • The global perspective on irritable bowel syndrome: a Rome Foundation-World Gastroenterology Organisation symposium
    • Sperber AD, Drossman DA, Quigley EM. The global perspective on irritable bowel syndrome: a Rome Foundation-World Gastroenterology Organisation symposium. Am J Gastroenterol 2012; 107: 1602-9.
    • (2012) Am J Gastroenterol , vol.107 , pp. 1602-1609
    • Sperber, A.D.1    Drossman, D.A.2    Quigley, E.M.3
  • 7
    • 0017848899 scopus 로고
    • Culture, illness, and care: clinical lessons from anthropologic and cross-cultural research
    • Kleinman A, Eisenberg L, Good B. Culture, illness, and care: clinical lessons from anthropologic and cross-cultural research. Ann Intern Med 1978; 88: 251-8.
    • (1978) Ann Intern Med , vol.88 , pp. 251-258
    • Kleinman, A.1    Eisenberg, L.2    Good, B.3
  • 10
    • 84875912655 scopus 로고    scopus 로고
    • From illness as culture to caregiving as moral experience
    • Kleinman A. From illness as culture to caregiving as moral experience. N Engl J Med 2013; 368: 1376-7.
    • (2013) N Engl J Med , vol.368 , pp. 1376-1377
    • Kleinman, A.1
  • 11
    • 0017576627 scopus 로고
    • The need for a new medical model: a challenge for biomedicine
    • Engel GL. The need for a new medical model: a challenge for biomedicine. Science 1977; 196: 129-36.
    • (1977) Science , vol.196 , pp. 129-136
    • Engel, G.L.1
  • 12
    • 0031812434 scopus 로고    scopus 로고
    • Presidential address: gastrointestinal illness and the biopsychosocial model
    • Drossman DA. Presidential address: gastrointestinal illness and the biopsychosocial model. Psychosom Med 1998; 60: 258-67.
    • (1998) Psychosom Med , vol.60 , pp. 258-267
    • Drossman, D.A.1
  • 13
    • 84890137978 scopus 로고    scopus 로고
    • Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern
    • Su AM, Shih W, Presson AP, Chang L. Characterization of symptoms in irritable bowel syndrome with mixed bowel habit pattern. Neurogastroenterol Motil 2014; 26: 36-45.
    • (2014) Neurogastroenterol Motil , vol.26 , pp. 36-45
    • Su, A.M.1    Shih, W.2    Presson, A.P.3    Chang, L.4
  • 15
    • 52049122410 scopus 로고    scopus 로고
    • Genes and irritable bowel syndrome: is there a link?
    • Saito YA. Genes and irritable bowel syndrome: is there a link? Curr Gastroenterol Rep 2008; 10: 355-62.
    • (2008) Curr Gastroenterol Rep , vol.10 , pp. 355-362
    • Saito, Y.A.1
  • 16
    • 84867852149 scopus 로고    scopus 로고
    • New paradigm for studying genetic contributions to irritable bowel syndrome
    • van Tilburg MA, Whitehead WE. New paradigm for studying genetic contributions to irritable bowel syndrome. Dig Dis Sci 2012; 57: 2484-6.
    • (2012) Dig Dis Sci , vol.57 , pp. 2484-2486
    • van Tilburg, M.A.1    Whitehead, W.E.2
  • 17
    • 84867828617 scopus 로고    scopus 로고
    • Peripheral mechanisms in irritable bowel syndrome
    • Camilleri M. Peripheral mechanisms in irritable bowel syndrome. N Engl J Med 2012; 367: 1626-35.
    • (2012) N Engl J Med , vol.367 , pp. 1626-1635
    • Camilleri, M.1
  • 18
    • 33646870356 scopus 로고    scopus 로고
    • Review article: intestinal serotonin signalling in irritable bowel syndrome
    • Mawe GM, Coates MD, Moses PL. Review article: intestinal serotonin signalling in irritable bowel syndrome. Aliment Pharmacol Ther 2006; 23: 1067-76.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 1067-1076
    • Mawe, G.M.1    Coates, M.D.2    Moses, P.L.3
  • 19
    • 70350566110 scopus 로고    scopus 로고
    • The putative role of the intestinal microbiota in the irritable bowel syndrome
    • Collins SM, Denou E, Verdu EF, Bercik P. The putative role of the intestinal microbiota in the irritable bowel syndrome. Dig Liver Dis 2009; 41: 850-3.
    • (2009) Dig Liver Dis , vol.41 , pp. 850-853
    • Collins, S.M.1    Denou, E.2    Verdu, E.F.3    Bercik, P.4
  • 20
    • 84859111005 scopus 로고    scopus 로고
    • Brain-gut axis: from basic understanding to treatment of IBS and related disorders
    • Camilleri M, Di Lorenzo C. Brain-gut axis: from basic understanding to treatment of IBS and related disorders. J Pediatr Gastroenterol Nutr 2012; 54: 446-53.
    • (2012) J Pediatr Gastroenterol Nutr , vol.54 , pp. 446-453
    • Camilleri, M.1    Di Lorenzo, C.2
  • 21
    • 2342453772 scopus 로고    scopus 로고
    • Pathophysiology as a basis for understanding symptom complexes and therapeutic targets
    • Camilleri M, Talley NJ. Pathophysiology as a basis for understanding symptom complexes and therapeutic targets. Neurogastroenterol Motil 2004; 16: 135-42.
    • (2004) Neurogastroenterol Motil , vol.16 , pp. 135-142
    • Camilleri, M.1    Talley, N.J.2
  • 22
    • 84930380712 scopus 로고    scopus 로고
    • Intestinal secretory mechanisms in irritable bowel syndrome-diarrhea
    • [Epub ahead of print].
    • Camilleri M. Intestinal secretory mechanisms in irritable bowel syndrome-diarrhea. Clin Gastroenterol Hepatol 2014. doi: 10.1016/j.cgh.2014.07.020. [Epub ahead of print].
    • (2014) Clin Gastroenterol Hepatol
    • Camilleri, M.1
  • 25
    • 84870866715 scopus 로고    scopus 로고
    • An update on post-infectious irritable bowel syndrome: role of genetics, immune activation, serotonin and altered microbiome
    • Spiller R, Lam C. An update on post-infectious irritable bowel syndrome: role of genetics, immune activation, serotonin and altered microbiome. J Neurogastroenterol Motil. 2012; 18: 258-68.
    • (2012) J Neurogastroenterol Motil. , vol.18 , pp. 258-268
    • Spiller, R.1    Lam, C.2
  • 29
    • 33846347644 scopus 로고    scopus 로고
    • The serotonin signaling system: from basic understanding to drug development for functional GI disorders
    • Gershon MD, Tack J. The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 2007; 132: 397-414.
    • (2007) Gastroenterology , vol.132 , pp. 397-414
    • Gershon, M.D.1    Tack, J.2
  • 30
    • 33749847073 scopus 로고    scopus 로고
    • Irritable bowel syndrome
    • Talley NJ. Irritable bowel syndrome. Intern Med J 2006; 36: 724-8.
    • (2006) Intern Med J , vol.36 , pp. 724-728
    • Talley, N.J.1
  • 33
    • 84856782266 scopus 로고    scopus 로고
    • Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy
    • Kenna GA, Roder-Hanna N, Leggio L, Zywiak WH, Clifford J, Edwards S, Kenna JA, Shoaff J et al. Association of the 5-HTT gene-linked promoter region (5-HTTLPR) polymorphism with psychiatric disorders: review of psychopathology and pharmacotherapy. Pharmgenomics Pers Med. 2012; 5: 19-35.
    • (2012) Pharmgenomics Pers Med. , vol.5 , pp. 19-35
    • Kenna, G.A.1    Roder-Hanna, N.2    Leggio, L.3    Zywiak, W.H.4    Clifford, J.5    Edwards, S.6    Kenna, J.A.7    Shoaff, J.8
  • 34
    • 50849102261 scopus 로고    scopus 로고
    • Review article: the psychoneuroimmunology of irritable bowel syndrome - an exploration of interactions between psychological, neurological and immunological observations
    • Arebi N, Gurmany S, Bullas D, Hobson A, Stagg A, Kamm M. Review article: the psychoneuroimmunology of irritable bowel syndrome - an exploration of interactions between psychological, neurological and immunological observations. Aliment Pharmacol Ther 2008; 28: 830-40.
    • (2008) Aliment Pharmacol Ther , vol.28 , pp. 830-840
    • Arebi, N.1    Gurmany, S.2    Bullas, D.3    Hobson, A.4    Stagg, A.5    Kamm, M.6
  • 35
    • 33744815210 scopus 로고    scopus 로고
    • A unifying hypothesis for the functional gastrointestinal disorders: really multiple diseases or one irritable gut?
    • Talley NJ. A unifying hypothesis for the functional gastrointestinal disorders: really multiple diseases or one irritable gut? Rev Gastroenterol Disord. 2006; 6: 72-8.
    • (2006) Rev Gastroenterol Disord. , vol.6 , pp. 72-78
    • Talley, N.J.1
  • 36
    • 84883456874 scopus 로고    scopus 로고
    • Post-infectious sequelae of travelers' diarrhea
    • Connor BA, Riddle MS. Post-infectious sequelae of travelers' diarrhea. J Travel Med. 2013; 20: 303-12.
    • (2013) J Travel Med. , vol.20 , pp. 303-312
    • Connor, B.A.1    Riddle, M.S.2
  • 37
    • 79953093222 scopus 로고    scopus 로고
    • Post-infectious irritable bowel syndrome: the past, the present and the future
    • Ghoshal UC, Ranjan P. Post-infectious irritable bowel syndrome: the past, the present and the future. J Gastroenterol Hepatol 2011; 26(Suppl. 3): 94-101.
    • (2011) J Gastroenterol Hepatol , vol.26 , pp. 94-101
    • Ghoshal, U.C.1    Ranjan, P.2
  • 38
    • 18944362443 scopus 로고    scopus 로고
    • Will corticosteroids and other anti-inflammatory agents be effective for diarrhea-predominant irritable bowel syndrome?
    • Crentsil V. Will corticosteroids and other anti-inflammatory agents be effective for diarrhea-predominant irritable bowel syndrome? Med Hypotheses 2005; 65: 97-102.
    • (2005) Med Hypotheses , vol.65 , pp. 97-102
    • Crentsil, V.1
  • 39
    • 8344251723 scopus 로고    scopus 로고
    • The pathophysiology of irritable bowel syndrome
    • Schwetz I, Bradesi S, Mayer EA. The pathophysiology of irritable bowel syndrome. Minerva Med 2004; 95: 419-26.
    • (2004) Minerva Med , vol.95 , pp. 419-426
    • Schwetz, I.1    Bradesi, S.2    Mayer, E.A.3
  • 40
    • 33645068615 scopus 로고    scopus 로고
    • Intestinal epithelial cell signalling and host-derived negative regulators under chronic inflammation: to be or not to be activated determines the balance towards commensal bacteria
    • Haller D. Intestinal epithelial cell signalling and host-derived negative regulators under chronic inflammation: to be or not to be activated determines the balance towards commensal bacteria. Neurogastroenterol Motil 2006; 18: 184-99.
    • (2006) Neurogastroenterol Motil , vol.18 , pp. 184-199
    • Haller, D.1
  • 41
    • 84885605276 scopus 로고    scopus 로고
    • Intestinal microbiota and immune function in the pathogenesis of irritable bowel syndrome
    • Ringel Y, Maharshak N. Intestinal microbiota and immune function in the pathogenesis of irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2013; 305: G529-41.
    • (2013) Am J Physiol Gastrointest Liver Physiol , vol.305 , pp. G529-G541
    • Ringel, Y.1    Maharshak, N.2
  • 42
    • 77953243617 scopus 로고    scopus 로고
    • The intestinal barrier and its regulation by neuroimmune factors
    • Keita AV, Soderholm JD. The intestinal barrier and its regulation by neuroimmune factors. Neurogastroenterol Motil 2010; 22: 718-33.
    • (2010) Neurogastroenterol Motil , vol.22 , pp. 718-733
    • Keita, A.V.1    Soderholm, J.D.2
  • 43
    • 34548853957 scopus 로고    scopus 로고
    • Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome
    • Rijnierse A, Nijkamp FP, Kraneveld AD. Mast cells and nerves tickle in the tummy: implications for inflammatory bowel disease and irritable bowel syndrome. Pharmacol Ther 2007; 116: 207-35.
    • (2007) Pharmacol Ther , vol.116 , pp. 207-235
    • Rijnierse, A.1    Nijkamp, F.P.2    Kraneveld, A.D.3
  • 44
    • 84865423557 scopus 로고    scopus 로고
    • Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome
    • Martinez C, Gonzalez-Castro A, Vicario M, Santos J. Cellular and molecular basis of intestinal barrier dysfunction in the irritable bowel syndrome. Gut Liv 2012; 6: 305-15.
    • (2012) Gut Liv , vol.6 , pp. 305-315
    • Martinez, C.1    Gonzalez-Castro, A.2    Vicario, M.3    Santos, J.4
  • 48
    • 84899074874 scopus 로고    scopus 로고
    • Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets
    • Dupont HL. Review article: evidence for the role of gut microbiota in irritable bowel syndrome and its potential influence on therapeutic targets. Aliment Pharmacol Ther 2014; 39: 1033-42.
    • (2014) Aliment Pharmacol Ther , vol.39 , pp. 1033-1042
    • Dupont, H.L.1
  • 49
    • 67649443898 scopus 로고    scopus 로고
    • Prebiotics, immune function, infection and inflammation: a review of the evidence
    • Lomax AR, Calder PC. Prebiotics, immune function, infection and inflammation: a review of the evidence. Br J Nutr 2009; 101: 633-58.
    • (2009) Br J Nutr , vol.101 , pp. 633-658
    • Lomax, A.R.1    Calder, P.C.2
  • 50
    • 84861750253 scopus 로고    scopus 로고
    • Intestinal microbiota, pathophysiology and translation to probiotic use in patients with irritable bowel syndrome
    • Almansa C, Agrawal A, Houghton LA. Intestinal microbiota, pathophysiology and translation to probiotic use in patients with irritable bowel syndrome. Expert Rev Gastroenterol Hepatol 2012; 6: 383-98.
    • (2012) Expert Rev Gastroenterol Hepatol , vol.6 , pp. 383-398
    • Almansa, C.1    Agrawal, A.2    Houghton, L.A.3
  • 51
    • 67449091876 scopus 로고    scopus 로고
    • Bifidobacterium infantis 35624: a novel probiotic for the treatment of irritable bowel syndrome
    • Brenner DM, Chey WD. Bifidobacterium infantis 35624: a novel probiotic for the treatment of irritable bowel syndrome. Rev Gastroenterol Disord. 2009; 9: 7-15.
    • (2009) Rev Gastroenterol Disord. , vol.9 , pp. 7-15
    • Brenner, D.M.1    Chey, W.D.2
  • 52
    • 84884906412 scopus 로고    scopus 로고
    • Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice - an evidence-based international guide
    • Hungin AP, Mulligan C, Pot B, Whorwell P, Agreus L, Fracasso P, Lionis C, Mendive J et al. Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice - an evidence-based international guide. Aliment Pharmacol Ther 2013; 38: 864-86.
    • (2013) Aliment Pharmacol Ther , vol.38 , pp. 864-886
    • Hungin, A.P.1    Mulligan, C.2    Pot, B.3    Whorwell, P.4    Agreus, L.5    Fracasso, P.6    Lionis, C.7    Mendive, J.8
  • 53
    • 84876481254 scopus 로고    scopus 로고
    • A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function
    • e903.
    • Vazquez-Roque MI, Camilleri M, Smyrk T, Murray JA, Marietta E, O'Neill J, Carlson P, Lamsam J et al. A controlled trial of gluten-free diet in patients with irritable bowel syndrome-diarrhea: effects on bowel frequency and intestinal function. Gastroenterology 2013; 144: 903-11 e903.
    • (2013) Gastroenterology , vol.144 , pp. 903-911
    • Vazquez-Roque, M.I.1    Camilleri, M.2    Smyrk, T.3    Murray, J.A.4    Marietta, E.5    O'Neill, J.6    Carlson, P.7    Lamsam, J.8
  • 57
    • 84919714351 scopus 로고    scopus 로고
    • Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS
    • Bajor A, Tornblom H, Rudling M, Ung KA, Simren M. Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS. Gut 2015; 64: 84-92.
    • (2015) Gut , vol.64 , pp. 84-92
    • Bajor, A.1    Tornblom, H.2    Rudling, M.3    Ung, K.A.4    Simren, M.5
  • 58
    • 84903814274 scopus 로고    scopus 로고
    • Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy
    • Walters JR. Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy. Nat Rev Gastroenterol Hepatol 2014; 11: 426-34.
    • (2014) Nat Rev Gastroenterol Hepatol , vol.11 , pp. 426-434
    • Walters, J.R.1
  • 60
    • 84861201380 scopus 로고    scopus 로고
    • Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome
    • e246-517.
    • Duboc H, Rainteau D, Rajca S, Humbert L, Farabos D, Maubert M, Grondin V, Jouet P et al. Increase in fecal primary bile acids and dysbiosis in patients with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol Motil 2012; 24: 513-20, e246-517.
    • (2012) Neurogastroenterol Motil , vol.24 , pp. 513-520
    • Duboc, H.1    Rainteau, D.2    Rajca, S.3    Humbert, L.4    Farabos, D.5    Maubert, M.6    Grondin, V.7    Jouet, P.8
  • 61
    • 84884355706 scopus 로고    scopus 로고
    • Bowel functions, fecal unconjugated primary and secondary bile acids, and colonic transit in patients with irritable bowel syndrome
    • e1271.
    • Shin A, Camilleri M, Vijayvargiya P, Busciglio I, Burton D, Ryks M, Rhoten D, Lueke A et al. Bowel functions, fecal unconjugated primary and secondary bile acids, and colonic transit in patients with irritable bowel syndrome. Clin Gastroenterol Hepatol 2013; 11: 1270-5 e1271.
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 1270-1275
    • Shin, A.1    Camilleri, M.2    Vijayvargiya, P.3    Busciglio, I.4    Burton, D.5    Ryks, M.6    Rhoten, D.7    Lueke, A.8
  • 63
    • 0035258445 scopus 로고    scopus 로고
    • Brain-gut interaction in irritable bowel syndrome: new findings of a multicomponent disease model
    • Schmulson MJ. Brain-gut interaction in irritable bowel syndrome: new findings of a multicomponent disease model. Isr Med Assoc J. 2001; 3: 104-10.
    • (2001) Isr Med Assoc J. , vol.3 , pp. 104-110
    • Schmulson, M.J.1
  • 64
    • 79960645242 scopus 로고    scopus 로고
    • Gut feelings: the emerging biology of gut-brain communication
    • Mayer EA. Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci 2011; 12: 453-66.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 453-466
    • Mayer, E.A.1
  • 65
    • 0036083295 scopus 로고    scopus 로고
    • Evolving pathophysiologic models of functional gastrointestinal disorders
    • Mayer EA, Collins SM. Evolving pathophysiologic models of functional gastrointestinal disorders. Gastroenterology 2002; 122: 2032-48.
    • (2002) Gastroenterology , vol.122 , pp. 2032-2048
    • Mayer, E.A.1    Collins, S.M.2
  • 66
    • 0028338434 scopus 로고
    • Basic and clinical aspects of visceral hyperalgesia
    • Mayer EA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994; 107: 271-93.
    • (1994) Gastroenterology , vol.107 , pp. 271-293
    • Mayer, E.A.1    Gebhart, G.F.2
  • 67
    • 0035678622 scopus 로고    scopus 로고
    • Basic pathophysiologic mechanisms in irritable bowel syndrome
    • Mayer EA, Naliboff BD, Chang L. Basic pathophysiologic mechanisms in irritable bowel syndrome. Dig Dis 2001; 19: 212-8.
    • (2001) Dig Dis , vol.19 , pp. 212-218
    • Mayer, E.A.1    Naliboff, B.D.2    Chang, L.3
  • 68
    • 67651030390 scopus 로고    scopus 로고
    • Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging
    • Price DD, Craggs JG, Zhou Q, Verne GN, Perlstein WM, Robinson ME. Widespread hyperalgesia in irritable bowel syndrome is dynamically maintained by tonic visceral impulse input and placebo/nocebo factors: evidence from human psychophysics, animal models, and neuroimaging. NeuroImage 2009; 47: 995-1001.
    • (2009) NeuroImage , vol.47 , pp. 995-1001
    • Price, D.D.1    Craggs, J.G.2    Zhou, Q.3    Verne, G.N.4    Perlstein, W.M.5    Robinson, M.E.6
  • 69
    • 33746380579 scopus 로고    scopus 로고
    • Peripheral and central contributions to hyperalgesia in irritable bowel syndrome
    • Price DD, Zhou Q, Moshiree B, Robinson ME, Verne GN. Peripheral and central contributions to hyperalgesia in irritable bowel syndrome. J Pain. 2006; 7: 529-35.
    • (2006) J Pain. , vol.7 , pp. 529-535
    • Price, D.D.1    Zhou, Q.2    Moshiree, B.3    Robinson, M.E.4    Verne, G.N.5
  • 70
    • 33846697322 scopus 로고    scopus 로고
    • New insights into the pathogenesis and pathophysiology of irritable bowel syndrome
    • Ohman L, Simren M. New insights into the pathogenesis and pathophysiology of irritable bowel syndrome. Dig Liver Dis 2007; 39: 201-15.
    • (2007) Dig Liver Dis , vol.39 , pp. 201-215
    • Ohman, L.1    Simren, M.2
  • 71
    • 79954610817 scopus 로고    scopus 로고
    • Pooled analysis of brain activity in irritable bowel syndrome and controls during rectal balloon distension
    • e158.
    • Sheehan J, Gaman A, Vangel M, Kuo B. Pooled analysis of brain activity in irritable bowel syndrome and controls during rectal balloon distension. Neurogastroenterol Motil 2011; 23: 336-46 e158.
    • (2011) Neurogastroenterol Motil , vol.23 , pp. 336-346
    • Sheehan, J.1    Gaman, A.2    Vangel, M.3    Kuo, B.4
  • 72
    • 67649674676 scopus 로고    scopus 로고
    • Pathophysiology underlying irritable bowel syndrome - from the viewpoint of dysfunction of autonomic nervous system activity
    • Manabe N, Tanaka T, Hata J, Kusunoki H, Haruma K. Pathophysiology underlying irritable bowel syndrome - from the viewpoint of dysfunction of autonomic nervous system activity. J Smooth Muscle Res 2009; 45: 15-23.
    • (2009) J Smooth Muscle Res , vol.45 , pp. 15-23
    • Manabe, N.1    Tanaka, T.2    Hata, J.3    Kusunoki, H.4    Haruma, K.5
  • 73
    • 18944381758 scopus 로고    scopus 로고
    • Are cardiac syndrome X, irritable bowel syndrome and reflex sympathetic dystrophy examples of lateral medullary ischaemic syndromes?
    • Syme P. Are cardiac syndrome X, irritable bowel syndrome and reflex sympathetic dystrophy examples of lateral medullary ischaemic syndromes? Med Hypotheses 2005; 65: 145-8.
    • (2005) Med Hypotheses , vol.65 , pp. 145-148
    • Syme, P.1
  • 74
    • 0001222673 scopus 로고
    • When is a little information a dangerous thing? Coping with stressful life events by monitoring vs blunting
    • In: Levine S, Ursin H, eds. New York, NY: Plenum Press
    • Miller SM. When is a little information a dangerous thing? Coping with stressful life events by monitoring vs blunting. In: Levine S, Ursin H, eds. Coping and Health. New York, NY: Plenum Press, 1980: 145-69.
    • (1980) Coping and Health , pp. 145-169
    • Miller, S.M.1
  • 77
    • 0032894179 scopus 로고    scopus 로고
    • Review article: gender-related differences in functional gastrointestinal disorders
    • Mayer EA, Naliboff B, Lee O, Munakata J, Chang L. Review article: gender-related differences in functional gastrointestinal disorders. Aliment Pharmacol Ther 1999; 13(Suppl. 2): 65-9.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 65-69
    • Mayer, E.A.1    Naliboff, B.2    Lee, O.3    Munakata, J.4    Chang, L.5
  • 78
    • 33644848421 scopus 로고    scopus 로고
    • Rectal afferent hypersensitivity and compliance in irritable bowel syndrome: differences between diarrhoea-predominant and constipation-predominant subgroups
    • Zar S, Benson MJ, Kumar D. Rectal afferent hypersensitivity and compliance in irritable bowel syndrome: differences between diarrhoea-predominant and constipation-predominant subgroups. Eur J Gastroenterol Hepatol 2006; 18: 151-8.
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 151-158
    • Zar, S.1    Benson, M.J.2    Kumar, D.3
  • 79
    • 7344227274 scopus 로고    scopus 로고
    • Subtypes of constipation predominant irritable bowel syndrome based on rectal perception
    • Harraf F, Schmulson M, Saba L, Niazi N, Fass R, Munakata J, Diehl D, Mertz H et al. Subtypes of constipation predominant irritable bowel syndrome based on rectal perception. Gut 1998; 43: 388-94.
    • (1998) Gut , vol.43 , pp. 388-394
    • Harraf, F.1    Schmulson, M.2    Saba, L.3    Niazi, N.4    Fass, R.5    Munakata, J.6    Diehl, D.7    Mertz, H.8
  • 80
    • 46349106355 scopus 로고    scopus 로고
    • Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain
    • Akbar A, Yiangou Y, Facer P, Walters JR, Anand P, Ghosh S. Increased capsaicin receptor TRPV1-expressing sensory fibres in irritable bowel syndrome and their correlation with abdominal pain. Gut 2008; 57: 923-9.
    • (2008) Gut , vol.57 , pp. 923-929
    • Akbar, A.1    Yiangou, Y.2    Facer, P.3    Walters, J.R.4    Anand, P.5    Ghosh, S.6
  • 81
    • 84891928594 scopus 로고    scopus 로고
    • Sensitivity testing in irritable bowel syndrome with rectal capsaicin stimulations: role of TRPV1 upregulation and sensitization in visceral hypersensitivity?
    • van Wanrooij SJ, Wouters MM, Van Oudenhove L, Vanbrabant W, Mondelaers S, Kollmann P, Kreutz F, Schemann M et al. Sensitivity testing in irritable bowel syndrome with rectal capsaicin stimulations: role of TRPV1 upregulation and sensitization in visceral hypersensitivity? Am J Gastroenterol 2014; 109: 99-109.
    • (2014) Am J Gastroenterol , vol.109 , pp. 99-109
    • van Wanrooij, S.J.1    Wouters, M.M.2    Van Oudenhove, L.3    Vanbrabant, W.4    Mondelaers, S.5    Kollmann, P.6    Kreutz, F.7    Schemann, M.8
  • 82
    • 84888293106 scopus 로고    scopus 로고
    • Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate
    • e1-11.
    • Castro J, Harrington AM, Hughes PA, Martin CM, Ge P, Shea CM, Jin H, Jacobson S et al. Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3', 5'-monophosphate. Gastroenterology 2013; 145: 1334-46, e1-11.
    • (2013) Gastroenterology , vol.145 , pp. 1334-1346
    • Castro, J.1    Harrington, A.M.2    Hughes, P.A.3    Martin, C.M.4    Ge, P.5    Shea, C.M.6    Jin, H.7    Jacobson, S.8
  • 83
    • 84881644234 scopus 로고    scopus 로고
    • Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome
    • Ellingson BM, Mayer E, Harris RJ, Ashe-McNally C, Naliboff BD, Labus JS, Tillisch K. Diffusion tensor imaging detects microstructural reorganization in the brain associated with chronic irritable bowel syndrome. Pain 2013; 154: 1528-41.
    • (2013) Pain , vol.154 , pp. 1528-1541
    • Ellingson, B.M.1    Mayer, E.2    Harris, R.J.3    Ashe-McNally, C.4    Naliboff, B.D.5    Labus, J.S.6    Tillisch, K.7
  • 84
    • 84885018903 scopus 로고    scopus 로고
    • Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment
    • Letzen JE, Craggs JG, Perlstein WM, Price DD, Robinson ME. Functional connectivity of the default mode network and its association with pain networks in irritable bowel patients assessed via lidocaine treatment. J Pain. 2013; 14: 1077-87.
    • (2013) J Pain. , vol.14 , pp. 1077-1087
    • Letzen, J.E.1    Craggs, J.G.2    Perlstein, W.M.3    Price, D.D.4    Robinson, M.E.5
  • 87
    • 84884284142 scopus 로고    scopus 로고
    • Sex differences in emotion-related cognitive processes in irritable bowel syndrome and healthy control subjects
    • Labus JS, Gupta A, Coveleskie K, Tillisch K, Kilpatrick L, Jarcho J, Feier N, Bueller J et al. Sex differences in emotion-related cognitive processes in irritable bowel syndrome and healthy control subjects. Pain 2013; 154: 2088-99.
    • (2013) Pain , vol.154 , pp. 2088-2099
    • Labus, J.S.1    Gupta, A.2    Coveleskie, K.3    Tillisch, K.4    Kilpatrick, L.5    Jarcho, J.6    Feier, N.7    Bueller, J.8
  • 89
    • 84892785304 scopus 로고    scopus 로고
    • Visceral sensitivity correlates with decreased regional gray matter volume in healthy volunteers: a voxel-based morphometry study
    • Elsenbruch S, Schmid J, Kullmann JS, Kattoor J, Theysohn N, Forsting M, Kotsis V. Visceral sensitivity correlates with decreased regional gray matter volume in healthy volunteers: a voxel-based morphometry study. Pain 2014; 155: 244-9.
    • (2014) Pain , vol.155 , pp. 244-249
    • Elsenbruch, S.1    Schmid, J.2    Kullmann, J.S.3    Kattoor, J.4    Theysohn, N.5    Forsting, M.6    Kotsis, V.7
  • 90
    • 0036084196 scopus 로고    scopus 로고
    • Evolving concepts in the pathophysiology of functional gastrointestinal disorder
    • Hunt RH. Evolving concepts in the pathophysiology of functional gastrointestinal disorder. J Clin Gastroenterol 2002; 35: S2-6.
    • (2002) J Clin Gastroenterol , vol.35 , pp. S2-S6
    • Hunt, R.H.1
  • 91
    • 84878607279 scopus 로고    scopus 로고
    • Which psychological factors exacerbate irritable bowel syndrome? Development of a comprehensive model
    • van Tilburg MA, Palsson OS, Whitehead WE. Which psychological factors exacerbate irritable bowel syndrome? Development of a comprehensive model. J Psychosom Res 2013; 74: 486-92.
    • (2013) J Psychosom Res , vol.74 , pp. 486-492
    • van Tilburg, M.A.1    Palsson, O.S.2    Whitehead, W.E.3
  • 92
    • 80055022363 scopus 로고    scopus 로고
    • Patient-reported outcomes for irritable bowel syndrome are associated with patients' severity ratings of gastrointestinal symptoms and psychological factors
    • e951.
    • Lackner J, Jaccard J, Baum C, Smith A, Krasner S, Katz L, Firth R, Raby T et al. Patient-reported outcomes for irritable bowel syndrome are associated with patients' severity ratings of gastrointestinal symptoms and psychological factors. Clin Gastroenterol Hepatol 2011; 9: 957-64 e951.
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 957-964
    • Lackner, J.1    Jaccard, J.2    Baum, C.3    Smith, A.4    Krasner, S.5    Katz, L.6    Firth, R.7    Raby, T.8
  • 93
    • 84893761449 scopus 로고    scopus 로고
    • The impact of physical complaints, social environment, and psychological functioning on IBS patients' health perceptions: looking beyond GI symptom severity
    • Lackner JM, Gudleski GD, Thakur ER, Stewart TJ, Iacobucci GJ, Spiegel BM. The impact of physical complaints, social environment, and psychological functioning on IBS patients' health perceptions: looking beyond GI symptom severity. Am J Gastroenterol 2014; 109: 224-33.
    • (2014) Am J Gastroenterol , vol.109 , pp. 224-233
    • Lackner, J.M.1    Gudleski, G.D.2    Thakur, E.R.3    Stewart, T.J.4    Iacobucci, G.J.5    Spiegel, B.M.6
  • 94
    • 34548127063 scopus 로고    scopus 로고
    • Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity
    • Dorn SD, Palsson OS, Thiwan SI, Kanazawa M, Clark WC, van Tilburg MA, Drossman DA, Scarlett Y et al. Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity. Gut 2007; 56: 1202-9.
    • (2007) Gut , vol.56 , pp. 1202-1209
    • Dorn, S.D.1    Palsson, O.S.2    Thiwan, S.I.3    Kanazawa, M.4    Clark, W.C.5    van Tilburg, M.A.6    Drossman, D.A.7    Scarlett, Y.8
  • 95
    • 84888235650 scopus 로고    scopus 로고
    • Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel syndrome
    • e1251-1253.
    • Labus JS, Hubbard CS, Bueller J, Ebrat B, Tillisch K, Chen M, Stains J, Dukes GE et al. Impaired emotional learning and involvement of the corticotropin-releasing factor signaling system in patients with irritable bowel syndrome. Gastroenterology 2013; 145: 1253-61, e1251-1253.
    • (2013) Gastroenterology , vol.145 , pp. 1253-1261
    • Labus, J.S.1    Hubbard, C.S.2    Bueller, J.3    Ebrat, B.4    Tillisch, K.5    Chen, M.6    Stains, J.7    Dukes, G.E.8
  • 97
    • 84871978907 scopus 로고    scopus 로고
    • Randomised clinical trial: symptoms of the irritable bowel syndrome are improved by a psycho-education group intervention
    • Labus J, Gupta A, Gill HK, Posserud I, Mayer M, Raeen H, Bolus R, Simren M et al. Randomised clinical trial: symptoms of the irritable bowel syndrome are improved by a psycho-education group intervention. Aliment Pharmacol Ther 2013; 37: 304-15.
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 304-315
    • Labus, J.1    Gupta, A.2    Gill, H.K.3    Posserud, I.4    Mayer, M.5    Raeen, H.6    Bolus, R.7    Simren, M.8
  • 100
    • 34848832166 scopus 로고    scopus 로고
    • Twin studies used to prove that the comorbidity of major depressive disorder with IBS is NOT influenced by heredity
    • Whitehead WE. Twin studies used to prove that the comorbidity of major depressive disorder with IBS is NOT influenced by heredity. Am J Gastroenterol 2007; 102: 2230-1.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2230-2231
    • Whitehead, W.E.1
  • 103
    • 0037288131 scopus 로고    scopus 로고
    • Abuse, dissociation, and somatization in irritable bowel syndrome: towards an explanatory model
    • Salmon P, Skaife K, Rhodes J. Abuse, dissociation, and somatization in irritable bowel syndrome: towards an explanatory model. J Behav Med 2003; 26: 1-18.
    • (2003) J Behav Med , vol.26 , pp. 1-18
    • Salmon, P.1    Skaife, K.2    Rhodes, J.3
  • 104
    • 33646068051 scopus 로고    scopus 로고
    • Parent attention versus distraction: impact on symptom complaints by children with and without chronic functional abdominal pain
    • Walker LS, Williams SE, Smith CA, Garber J, Van Slyke DA, Lipani TA. Parent attention versus distraction: impact on symptom complaints by children with and without chronic functional abdominal pain. Pain 2006; 122: 43-52.
    • (2006) Pain , vol.122 , pp. 43-52
    • Walker, L.S.1    Williams, S.E.2    Smith, C.A.3    Garber, J.4    Van Slyke, D.A.5    Lipani, T.A.6
  • 105
    • 78649657110 scopus 로고    scopus 로고
    • A cross-cultural perspective on irritable bowel syndrome
    • Gerson CD, Gerson MJ. A cross-cultural perspective on irritable bowel syndrome. Mt Sinai J Med 2010; 77: 707-12.
    • (2010) Mt Sinai J Med , vol.77 , pp. 707-712
    • Gerson, C.D.1    Gerson, M.J.2
  • 106
    • 67149113894 scopus 로고    scopus 로고
    • Early life stress and pain: an important link to functional bowel disorders
    • Miranda A. Early life stress and pain: an important link to functional bowel disorders. Pediatr Ann 2009; 38: 279-82.
    • (2009) Pediatr Ann , vol.38 , pp. 279-282
    • Miranda, A.1
  • 108
    • 47249141324 scopus 로고    scopus 로고
    • Pathophysiological mechanisms of stress-induced intestinal damage
    • Gareau MG, Silva MA, Perdue MH. Pathophysiological mechanisms of stress-induced intestinal damage. Curr Mol Med 2008; 8: 274-81.
    • (2008) Curr Mol Med , vol.8 , pp. 274-281
    • Gareau, M.G.1    Silva, M.A.2    Perdue, M.H.3
  • 109
    • 84856190424 scopus 로고    scopus 로고
    • Stress and visceral pain: from animal models to clinical therapies
    • Larauche M, Mulak A, Tache Y. Stress and visceral pain: from animal models to clinical therapies. Exp Neurol 2012; 233: 49-67.
    • (2012) Exp Neurol , vol.233 , pp. 49-67
    • Larauche, M.1    Mulak, A.2    Tache, Y.3
  • 110
    • 67849089070 scopus 로고    scopus 로고
    • A role for corticotropin-releasing factor in functional gastrointestinal disorders
    • Tache Y, Kiank C, Stengel A. A role for corticotropin-releasing factor in functional gastrointestinal disorders. Curr Gastroenterol Rep 2009; 11: 270-7.
    • (2009) Curr Gastroenterol Rep , vol.11 , pp. 270-277
    • Tache, Y.1    Kiank, C.2    Stengel, A.3
  • 112
    • 34548142214 scopus 로고    scopus 로고
    • New insights in the etiology and pathophysiology of irritable bowel syndrome: contribution of neonatal stress models
    • Barreau F, Ferrier L, Fioramonti J, Bueno L. New insights in the etiology and pathophysiology of irritable bowel syndrome: contribution of neonatal stress models. Pediatr Res 2007; 62: 240-5.
    • (2007) Pediatr Res , vol.62 , pp. 240-245
    • Barreau, F.1    Ferrier, L.2    Fioramonti, J.3    Bueno, L.4
  • 113
    • 80053563519 scopus 로고    scopus 로고
    • Irritable bowel syndrome and co-morbid gastrointestinal and extra-gastrointestinal functional syndromes
    • Sperber AD, Dekel R. Irritable bowel syndrome and co-morbid gastrointestinal and extra-gastrointestinal functional syndromes. J Neurogastroenterol Motil. 2010; 16: 113-9.
    • (2010) J Neurogastroenterol Motil. , vol.16 , pp. 113-119
    • Sperber, A.D.1    Dekel, R.2
  • 114
    • 33947140969 scopus 로고    scopus 로고
    • Management of functional somatic syndromes
    • Henningsen P, Zipfel S, Herzog W. Management of functional somatic syndromes. Lancet 2007; 369: 946-55.
    • (2007) Lancet , vol.369 , pp. 946-955
    • Henningsen, P.1    Zipfel, S.2    Herzog, W.3
  • 115
    • 84866315222 scopus 로고    scopus 로고
    • Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms?
    • Kim SE, Chang L. Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms? Neurogastroenterol Motil 2012; 24: 895-913.
    • (2012) Neurogastroenterol Motil , vol.24 , pp. 895-913
    • Kim, S.E.1    Chang, L.2
  • 116
    • 84861100182 scopus 로고    scopus 로고
    • The bowel and migraine: update on celiac disease and irritable bowel syndrome
    • Cady RK, Farmer K, Dexter JK, Hall J. The bowel and migraine: update on celiac disease and irritable bowel syndrome. Curr Pain Headache Rep 2012; 16: 278-86.
    • (2012) Curr Pain Headache Rep , vol.16 , pp. 278-286
    • Cady, R.K.1    Farmer, K.2    Dexter, J.K.3    Hall, J.4
  • 118
    • 77955013068 scopus 로고    scopus 로고
    • Fibromyalgia syndrome: a discussion of the syndrome and pharmacotherapy
    • Smith HS, Barkin RL. Fibromyalgia syndrome: a discussion of the syndrome and pharmacotherapy. Am J Ther 2010; 17: 418-39.
    • (2010) Am J Ther , vol.17 , pp. 418-439
    • Smith, H.S.1    Barkin, R.L.2
  • 119
    • 0035341150 scopus 로고    scopus 로고
    • A review of the evidence for overlap among unexplained clinical conditions
    • Aaron LA, Buchwald D. A review of the evidence for overlap among unexplained clinical conditions. Ann Intern Med 2001; 134: 868-81.
    • (2001) Ann Intern Med , vol.134 , pp. 868-881
    • Aaron, L.A.1    Buchwald, D.2
  • 120
    • 84870894947 scopus 로고    scopus 로고
    • Evidence for overlap between urological and nonurological unexplained clinical conditions
    • Bullones Rodriguez MA, Afari N, Buchwald DS. Evidence for overlap between urological and nonurological unexplained clinical conditions. J Urol 2013; 189: S66-74.
    • (2013) J Urol , vol.189 , pp. S66-S74
    • Bullones Rodriguez, M.A.1    Afari, N.2    Buchwald, D.S.3
  • 121
    • 0032216674 scopus 로고    scopus 로고
    • Intestinal and extraintestinal symptoms in functional gastrointestinal disorders
    • Mayer EA, Fass R, Fullerton S. Intestinal and extraintestinal symptoms in functional gastrointestinal disorders. Eur J Surg Suppl 1998; (583): 29-31.
    • (1998) Eur J Surg Suppl , Issue.583 , pp. 29-31
    • Mayer, E.A.1    Fass, R.2    Fullerton, S.3
  • 122
    • 79951579664 scopus 로고    scopus 로고
    • Central sensitization: implications for the diagnosis and treatment of pain
    • Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain 2011; 152: S2-15.
    • (2011) Pain , vol.152 , pp. S2-15
    • Woolf, C.J.1
  • 123
    • 79951771464 scopus 로고    scopus 로고
    • Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders
    • Kindler LL, Bennett RM, Jones KD. Central sensitivity syndromes: mounting pathophysiologic evidence to link fibromyalgia with other common chronic pain disorders. Pain Manag Nurs. 2011; 12: 15-24.
    • (2011) Pain Manag Nurs. , vol.12 , pp. 15-24
    • Kindler, L.L.1    Bennett, R.M.2    Jones, K.D.3
  • 124
    • 70749118211 scopus 로고    scopus 로고
    • Further strategies for treating fibromyalgia: the role of serotonin and norepinephrine reuptake inhibitors
    • Mease PJ. Further strategies for treating fibromyalgia: the role of serotonin and norepinephrine reuptake inhibitors. Am J Med 2009; 122: S44-55.
    • (2009) Am J Med , vol.122 , pp. S44-S55
    • Mease, P.J.1
  • 125
    • 84860600115 scopus 로고    scopus 로고
    • Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions
    • Staud R. Abnormal endogenous pain modulation is a shared characteristic of many chronic pain conditions. Expert Rev Neurother 2012; 12: 577-85.
    • (2012) Expert Rev Neurother , vol.12 , pp. 577-585
    • Staud, R.1
  • 126
    • 84871533632 scopus 로고    scopus 로고
    • Is chronic fatigue syndrome the same illness as fibromyalgia: evaluating the 'single syndrome' hypothesis
    • Abbi B, Natelson BH. Is chronic fatigue syndrome the same illness as fibromyalgia: evaluating the 'single syndrome' hypothesis. QJM 2013; 106: 3-9.
    • (2013) QJM , vol.106 , pp. 3-9
    • Abbi, B.1    Natelson, B.H.2
  • 127
    • 33645802799 scopus 로고    scopus 로고
    • The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors?
    • Aggarwal VR, McBeth J, Zakrzewska JM, Lunt M, Macfarlane GJ. The epidemiology of chronic syndromes that are frequently unexplained: do they have common associated factors? Int J Epidemiol 2006; 35: 468-76.
    • (2006) Int J Epidemiol , vol.35 , pp. 468-476
    • Aggarwal, V.R.1    McBeth, J.2    Zakrzewska, J.M.3    Lunt, M.4    Macfarlane, G.J.5


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