-
2
-
-
77949263115
-
Pathogenesis of IBS: Role of infl ammation, immunity and neuroimmune interactions
-
Ohman L, Simren M. Pathogenesis of IBS: Role of infl ammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol 2010;7:163-73
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 163-173
-
-
Ohman, L.1
Simren, M.2
-
4
-
-
22844433075
-
Relationship between symptoms and hypersensitivity to rectal distension in patients with irritable bowel syndrome
-
Kuiken SD, Lindeboom R, Tytgat GN et al. Relationship between symptoms and hypersensitivity to rectal distension in patients with irritable bowel syndrome. Aliment Pharmacol Ther 2005;22:157-64
-
(2005)
Aliment Pharmacol Ther
, vol.22
, pp. 157-164
-
-
Kuiken, S.D.1
Lindeboom, R.2
Tytgat, G.N.3
-
5
-
-
77956102855
-
The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome
-
Klooker TK, Braak B, Koopman KE et al. The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome. Gut 2010;59:1213-21
-
(2010)
Gut
, vol.59
, pp. 1213-1221
-
-
Klooker, T.K.1
Braak, B.2
Koopman, K.E.3
-
6
-
-
45849087283
-
Prospective study of motor, sensory, psychologic, and autonomic functions in patients with irritable bowel syndrome
-
Camilleri M, McKinzie S, Busciglio I et al. Prospective study of motor, sensory, psychologic, and autonomic functions in patients with irritable bowel syndrome. Clin Gastroenterol Hepatol 2008;6:772-81
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 772-781
-
-
Camilleri, M.1
McKinzie, S.2
Busciglio, I.3
-
7
-
-
0028113634
-
Evidence for the hypersensitivity of lumbar splanchnic aff erents in irritable bowel syndrome
-
Lembo T, Munakata J, Mertz H et al. Evidence for the hypersensitivity of lumbar splanchnic aff erents in irritable bowel syndrome. Gastroenterology 1994;107:1686-96
-
(1994)
Gastroenterology
, vol.107
, pp. 1686-1696
-
-
Lembo, T.1
Munakata, J.2
Mertz, H.3
-
8
-
-
0029022779
-
Altered rectal perception is a biological marker of patients with irritable bowel syndrome
-
Mertz H, Naliboff B, Munakata J et al. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995;109:40-52
-
(1995)
Gastroenterology
, vol.109
, pp. 40-52
-
-
Mertz, H.1
Naliboff, B.2
Munakata, J.3
-
9
-
-
47749148828
-
Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome
-
Sabate JM, Veyrac M, Mion F et al. Relationship between rectal sensitivity, symptoms intensity and quality of life in patients with irritable bowel syndrome. Aliment Pharmacol Ther 2008;28:484-90
-
(2008)
Aliment Pharmacol Ther
, vol.28
, pp. 484-490
-
-
Sabate, J.M.1
Veyrac, M.2
Mion, F.3
-
10
-
-
34848856669
-
Altered rectal perception in irritable bowel syndrome is associated with symptom severity
-
Posserud I, Syrous A, Lindstrom L et al. Altered rectal perception in irritable bowel syndrome is associated with symptom severity. Gastroenterology 2007;133:1113-23
-
(2007)
Gastroenterology
, vol.133
, pp. 1113-1123
-
-
Posserud, I.1
Syrous, A.2
Lindstrom, L.3
-
11
-
-
39949083748
-
Symptom severity but not psychopathology predicts visceral hypersensitivity in irritable bowel syndrome
-
van der Veek PP, Van Rood YR, Masclee AA. Symptom severity but not psychopathology predicts visceral hypersensitivity in irritable bowel syndrome. Clin Gastroenterol Hepatol 2008;6:321-8
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 321-328
-
-
Van Der Veek, P.P.1
Van Rood, Y.R.2
Masclee, A.A.3
-
12
-
-
34250793903
-
Relationship between anxiety and gastric sensorimotor function in functional dyspepsia
-
Van OL, Vandenberghe J, Geeraerts B, et al. Relationship between anxiety and gastric sensorimotor function in functional dyspepsia. Psychosom Med 2007;69:455-63
-
(2007)
Psychosom Med
, vol.69
, pp. 455-463
-
-
Van, O.L.1
Vandenberghe, J.2
Geeraerts, B.3
-
13
-
-
77950804750
-
Aff ective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: An fMRI study
-
Elsenbruch S, Rosenberger C, Enck P et al. Aff ective disturbances modulate the neural processing of visceral pain stimuli in irritable bowel syndrome: An fMRI study. Gut 2010;59:489-95
-
(2010)
Gut
, vol.59
, pp. 489-495
-
-
Elsenbruch, S.1
Rosenberger, C.2
Enck, P.3
-
14
-
-
33846077125
-
Peripheral and central mechanisms of visceral sensitization in man
-
Suppl
-
Anand P, Aziz Q, Willert R et al. Peripheral and central mechanisms of visceral sensitization in man. Neurogastroenterol Motil 2007;19 (1 Suppl):29-46
-
(2007)
Neurogastroenterol Motil
, vol.19
, Issue.1
, pp. 29-46
-
-
Anand, P.1
Aziz, Q.2
Willert, R.3
-
15
-
-
84861167356
-
Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome
-
Feng B, La JH, Schwartz ES et al. Irritable bowel syndrome: Methods, mechanisms, and pathophysiology. Neural and neuro-immune mechanisms of visceral hypersensitivity in irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 2012;302:G1085-98
-
(2012)
Am J Physiol Gastrointest Liver Physiol
, vol.302
-
-
Feng, B.1
La, J.H.2
Schwartz, E.S.3
-
16
-
-
78149359626
-
Nociceptor sensitization in pain pathogenesis
-
Gold MS, Gebhart GF. Nociceptor sensitization in pain pathogenesis. Nat Med 2010;16:1248-57
-
(2010)
Nat Med
, vol.16
, pp. 1248-1257
-
-
Gold, M.S.1
Gebhart, G.F.2
-
17
-
-
38349132228
-
TRPV1 receptor signaling mediates aff erent nerve sensitization during colitis-induced motility disorders in rats
-
De Schepper HU, De Man JG, Ruyssers NE et al. TRPV1 receptor signaling mediates aff erent nerve sensitization during colitis-induced motility disorders in rats. Am J Physiol Gastrointest Liver Physiol 2008;294:G245-53
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
De Schepper, H.U.1
De Man, J.G.2
Ruyssers, N.E.3
-
18
-
-
33847056759
-
The vanilloid receptor initiates and maintains colonic hypersensitivity induced by neonatal colon irritation in rats
-
Winston J, Shenoy M, Medley D et al. The vanilloid receptor initiates and maintains colonic hypersensitivity induced by neonatal colon irritation in rats. Gastroenterology 2007;132:615-27
-
(2007)
Gastroenterology
, vol.132
, pp. 615-627
-
-
Winston, J.1
Shenoy, M.2
Medley, D.3
-
19
-
-
61649097087
-
TRPV1-expressing sensory fi bres and IBS: Links with immune function
-
Hughes PA, Brierley SM, Martin CM et al. TRPV1-expressing sensory fi bres and IBS: Links with immune function. Gut 2009;58:465-6
-
(2009)
Gut
, vol.58
, pp. 465-466
-
-
Hughes, P.A.1
Brierley, S.M.2
Martin, C.M.3
-
20
-
-
34248138496
-
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
-
Szallasi A, Cortright DN, Blum CA et al. The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 2007;6:357-72
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 357-372
-
-
Szallasi, A.1
Cortright, D.N.2
Blum, C.A.3
-
21
-
-
46349084175
-
TRPV1: A new target for treatment of visceral pain in IBS?
-
Holzer P. TRPV1: A new target for treatment of visceral pain in IBS? Gut 2008;57:882-4
-
(2008)
Gut
, vol.57
, pp. 882-884
-
-
Holzer, P.1
-
22
-
-
70049108197
-
Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats
-
van den Wijngaard RM, Klooker TK, Welting O et al. Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats. Neurogastroenterol Motil 2009;21:1107-e94
-
(2009)
Neurogastroenterol Motil
, vol.21
-
-
Van Den Wijngaard, R.M.1
Klooker, T.K.2
Welting, O.3
-
23
-
-
34548670044
-
The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis
-
Miranda A, Nordstrom E, Mannem A et al. The role of transient receptor potential vanilloid 1 in mechanical and chemical visceral hyperalgesia following experimental colitis. Neuroscience 2007;148:1021-32
-
(2007)
Neuroscience
, vol.148
, pp. 1021-1032
-
-
Miranda, A.1
Nordstrom, E.2
Mannem, A.3
-
24
-
-
28044453285
-
The mechanosensitivity of mouse colon aff erent fi bers and their sensitization by infl ammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3
-
Jones RC III, Gebhart GF, Xu L. The mechanosensitivity of mouse colon aff erent fi bers and their sensitization by infl ammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3. J Neurosci 2005;25:10981-9
-
(2005)
J Neurosci
, vol.25
, pp. 10981-10989
-
-
Jones III, R.C.1
Gebhart, G.F.2
Xu, L.3
-
25
-
-
46349106355
-
Increased capsaicin receptor TRPV1-expressing sensory fi bres in irritable bowel syndrome and their correlation with abdominal pain
-
Akbar A, Yiangou Y, Facer P et al. Increased capsaicin receptor TRPV1-expressing sensory fi bres in irritable bowel syndrome and their correlation with abdominal pain. Gut 2008;57:923-9
-
(2008)
Gut
, vol.57
, pp. 923-929
-
-
Akbar, A.1
Yiangou, Y.2
Facer, P.3
-
26
-
-
0038499609
-
Gut pain and hyperalgesia induced by capsaicin: A human experimental model
-
Drewes AM, Schipper KP, Dimcevski G et al. Gut pain and hyperalgesia induced by capsaicin: A human experimental model. Pain 2003;104:333-41
-
(2003)
Pain
, vol.104
, pp. 333-341
-
-
Drewes, A.M.1
Schipper, K.P.2
Dimcevski, G.3
-
27
-
-
43049113946
-
Viscero-somatic refl exes in referred pain areas evoked by capsaicin stimulation of the human gut
-
Arendt-Nielsen L, Schipper KP, Dimcevski G et al. Viscero-somatic refl exes in referred pain areas evoked by capsaicin stimulation of the human gut. Eur J Pain 2008;12:544-51
-
(2008)
Eur J Pain
, vol.12
, pp. 544-551
-
-
Arendt-Nielsen, L.1
Schipper, K.P.2
Dimcevski, G.3
-
29
-
-
0023832668
-
GSRS-A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease
-
Svedlund J, Sjodin I, Dotevall G. GSRS-A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 1988;33:129-34
-
(1988)
Dig Dis Sci
, vol.33
, pp. 129-134
-
-
Svedlund, J.1
Sjodin, I.2
Dotevall, G.3
-
30
-
-
17344392308
-
A new mathematical model for relative quantifi cation in realtime RT-PCR
-
Pfaffl MW. A new mathematical model for relative quantifi cation in realtime RT-PCR. Nucleic Acids Res 2001;29:e45
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
31
-
-
8844269437
-
Jejunal aff erent nerve sensitivity in wild-Type and TRPV1 knockout mice
-
Rong W, Hillsley K, Davis JB et al. Jejunal aff erent nerve sensitivity in wild-Type and TRPV1 knockout mice. J Physiol 2004;560 (Part 3):867-81
-
(2004)
J Physiol
, vol.560
, Issue.PART 3
, pp. 867-881
-
-
Rong, W.1
Hillsley, K.2
Davis, J.B.3
-
32
-
-
58849093629
-
Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat
-
Hong S, Fan J, Kemmerer ES et al. Reciprocal changes in vanilloid (TRPV1) and endocannabinoid (CB1) receptors contribute to visceral hyperalgesia in the water avoidance stressed rat. Gut 2009;58:202-10
-
(2009)
Gut
, vol.58
, pp. 202-210
-
-
Hong, S.1
Fan, J.2
Kemmerer, E.S.3
-
33
-
-
77953718071
-
Expression of the TRPV1 receptor diff ers in quiescent infl ammatory bowel disease with or without abdominal pain
-
Akbar A, Yiangou Y, Facer P et al. Expression of the TRPV1 receptor diff ers in quiescent infl ammatory bowel disease with or without abdominal pain. Gut 2010;59:767-74
-
(2010)
Gut
, vol.59
, pp. 767-774
-
-
Akbar, A.1
Yiangou, Y.2
Facer, P.3
-
34
-
-
84862326009
-
Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome is there any relationship?
-
Braak B, Klooker TK, Wouters MM et al. Mucosal immune cell numbers and visceral sensitivity in patients with irritable bowel syndrome: Is there any relationship? Am J Gastroenterol 2012;107:15-26
-
(2012)
Am J Gastroenterol
, vol.107
, pp. 15-26
-
-
Braak, B.1
Klooker, T.K.2
Wouters, M.M.3
-
35
-
-
84863348106
-
Identifi cation of a cis-Acting element that localizes mRNA to synapses
-
Meer EJ, Wang DO, Kim S et al. Identifi cation of a cis-Acting element that localizes mRNA to synapses. Proc Natl Acad Sci USA 2012;109:4639-44
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 4639-4644
-
-
Meer, E.J.1
Wang, D.O.2
Kim, S.3
-
36
-
-
33845807365
-
Identifi cation of process-localized mRNAs from cultured rodent hippocampal neurons
-
Poon MM, Choi SH, Jamieson CA et al. Identifi cation of process-localized mRNAs from cultured rodent hippocampal neurons. J Neurosci 2006;26:13390-9
-
(2006)
J Neurosci
, vol.26
, pp. 13390-13399
-
-
Poon, M.M.1
Choi, S.H.2
Jamieson, C.A.3
-
37
-
-
77950792687
-
Potentiation of TRPV4 signalling by histamine and serotonin: An important mechanism for visceral hypersensitivity
-
Cenac N, Altier C, Motta JP et al. Potentiation of TRPV4 signalling by histamine and serotonin: An important mechanism for visceral hypersensitivity. Gut 2010;59:481-8
-
(2010)
Gut
, vol.59
, pp. 481-488
-
-
Cenac, N.1
Altier, C.2
Motta, J.P.3
-
38
-
-
25444506199
-
Diff erent contributions of ASIC channels 1a 2, and 3 in gastrointestinal mechanosensory function
-
Page AJ, Brierley SM, Martin CM et al. Diff erent contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function. Gut 2005;54:1408-15
-
(2005)
Gut
, vol.54
, pp. 1408-1415
-
-
Page, A.J.1
Brierley, S.M.2
Martin, C.M.3
-
39
-
-
79960369248
-
TRPA1 contributes to specifi c mechanically activated currents and sensory neuron mechanical hypersensitivity
-
Brierley SM, Castro J, Harrington AM et al. TRPA1 contributes to specifi c mechanically activated currents and sensory neuron mechanical hypersensitivity. J Physiol 2011;589 (Part 14):3575-93
-
(2011)
J Physiol
, vol.589
, Issue.PART 14
, pp. 3575-3593
-
-
Brierley, S.M.1
Castro, J.2
Harrington, A.M.3
-
40
-
-
38349036203
-
Reduced brainstem inhibition during anticipated pelvic visceral pain correlates wiThenhanced brain response to the visceral stimulus in women with irritable bowel syndrome
-
Berman SM, Naliboff BD, Suyenobu B et al. Reduced brainstem inhibition during anticipated pelvic visceral pain correlates wiThenhanced brain response to the visceral stimulus in women with irritable bowel syndrome. J Neurosci 2008;28:349-59 .
-
(2008)
J Neurosci
, vol.28
, pp. 349-359
-
-
Berman, S.M.1
Naliboff, B.D.2
Suyenobu, B.3
-
41
-
-
33750976200
-
Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls
-
Song GH, Venkatraman V, Ho KY et al. Cortical effects of anticipation and endogenous modulation of visceral pain assessed by functional brain MRI in irritable bowel syndrome patients and healthy controls. Pain 2006;126:79-90
-
(2006)
Pain
, vol.126
, pp. 79-90
-
-
Song, G.H.1
Venkatraman, V.2
Ho, K.Y.3
|