Hypercapnia inhibits autophagy and bacterial killing in human macrophages by increasing expression of Bcl-2 and Bcl-xL

Journal of Immunology

Volumn 194, Issue 11, 2015, Pages 5388-5396

  Casalino Matsuda, S Marina ^a   Nair, Aisha ^a   Beitel, Greg J ^b   Gates, Khalilah L ^a   Sporn, Peter H S ^a,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BAFILOMYCIN; CARBON DIOXIDE; LIPOPOLYSACCHARIDE; PEPTIDOMIMETIC AGENT; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN INHIBITOR; RAPAMYCIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; Z 36; 5-FLUORO-1-(3'-DIMETHYLAMINO)PROPYL-INDOLIN-2-ONE; APOPTOSIS REGULATORY PROTEIN; BCL2L1 PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; INDOLE DERIVATIVE; MEMBRANE PROTEIN; PROTEIN BCL X; PROTEIN BINDING;

ACIDOSIS; ARTICLE; AUTOPHAGY; BACTERICIDAL ACTIVITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; HUMAN; HUMAN CELL; HYPERCAPNIA; INNATE IMMUNITY; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; PSEUDOMONAS AERUGINOSA; STARVATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; BLOOD; CELL LINE; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG ALVEOLUS MACROPHAGE; LUNG DISEASE; MICROBIOLOGY; MOUSE; PATHOLOGY; PHAGOCYTOSIS; RNA INTERFERENCE;

ACIDOSIS; ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-X PROTEIN; CARBON DIOXIDE; CELL LINE; HUMANS; HYPERCAPNIA; INDOLES; LIPOPOLYSACCHARIDES; LUNG DISEASES; MACROPHAGES, ALVEOLAR; MEMBRANE PROTEINS; MICE; PHAGOCYTOSIS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-BCL-2; PSEUDOMONAS AERUGINOSA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIROLIMUS;

EID: 84929643553     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1500150     Document Type: Article

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