Combination treatment with ABT-737 and chloroquine in preclinical models of small cell lung cancer

Molecular Cancer

Volumn 12, Issue 1, 2013, Pages

  Zinn, Rebekah L ^a   Gardner, Eric E ^a   Dobromilskaya, Irina ^a   Murphy, Sara ^a   Marchionni, Luigi ^a   Hann, Christine L ^a   Rudin, Charles M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

ABT 737; Apoptosis; Autophagy; Chloroquine; Primary xenograft

Indexed keywords

4 [4 (4' CHLORO 2 BIPHENYLYLMETHYL) 1 PIPERAZINYL] N [4 [3 DIMETHYLAMINO 1 (PHENYLTHIOMETHYL)PROPYLAMINO] 3 NITROBENZENESULFONYL]BENZAMIDE; BECLIN 1; CASPASE 3; CHLOROQUINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; LUNG NON SMALL CELL CANCER; LUNG SMALL CELL CANCER; MOUSE; NONHUMAN; TREATMENT OUTCOME;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BIPHENYL COMPOUNDS; CELL PROLIFERATION; CELL SURVIVAL; CHLOROQUINE; DRUG RESISTANCE, NEOPLASM; FEMALE; GENE KNOCKDOWN TECHNIQUES; HUMANS; LUNG NEOPLASMS; MEMBRANE PROTEINS; MICE; MICE, NUDE; NITROPHENOLS; PIPERAZINES; RNA, SMALL INTERFERING; SMALL CELL LUNG CARCINOMA; SULFONAMIDES; TUMOR BURDEN; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS;

EID: 84874398169     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-12-16     Document Type: Article

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