-
1
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang J, Hui CC (2008) Hedgehog signaling in development and cancer. Dev Cell 15(6): 801-812.
-
(2008)
Dev Cell
, vol.15
, Issue.6
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
2
-
-
84879414522
-
The mechanisms of Hedgehog signalling and its roles in development and disease
-
Briscoe J, Thérond PP (2013) The mechanisms of Hedgehog signalling and its roles in development and disease. Nat Rev Mol Cell Biol 14(7):416-429.
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, Issue.7
, pp. 416-429
-
-
Briscoe, J.1
Thérond, P.P.2
-
3
-
-
0026761497
-
Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster
-
Préat T (1992) Characterization of Suppressor of fused, a complete suppressor of the fused segment polarity gene of Drosophila melanogaster. Genetics 132(3):725-736.
-
(1992)
Genetics
, vol.132
, Issue.3
, pp. 725-736
-
-
Préat, T.1
-
4
-
-
0032585515
-
Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
-
Ohlmeyer JT, Kalderon D (1998) Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator. Nature 396(6713):749-753.
-
(1998)
Nature
, vol.396
, Issue.6713
, pp. 749-753
-
-
Ohlmeyer, J.T.1
Kalderon, D.2
-
5
-
-
0033533714
-
Mouse Suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1
-
Ding Q, et al. (1999) Mouse Suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol 9(19):1119-1122.
-
(1999)
Curr Biol
, vol.9
, Issue.19
, pp. 1119-1122
-
-
Ding, Q.1
-
6
-
-
31744451535
-
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
-
Svärd J, et al. (2006) Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway. Dev Cell 10(2):187-197.
-
(2006)
Dev Cell
, vol.10
, Issue.2
, pp. 187-197
-
-
Svärd, J.1
-
7
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, et al. (2002) Mutations in SUFU predispose to medulloblastoma. Nat Genet 31(3):306-310.
-
(2002)
Nat Genet
, vol.31
, Issue.3
, pp. 306-310
-
-
Taylor, M.D.1
-
8
-
-
84866100107
-
Loss of SUFU function in familial multiple meningioma
-
Aavikko M, et al. (2012) Loss of SUFU function in familial multiple meningioma. Am J Hum Genet 91(3):520-526.
-
(2012)
Am J Hum Genet
, vol.91
, Issue.3
, pp. 520-526
-
-
Aavikko, M.1
-
9
-
-
0033582908
-
Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus
-
Méthot N, Basler K (1999) Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96(6):819-831.
-
(1999)
Cell
, vol.96
, Issue.6
, pp. 819-831
-
-
Méthot, N.1
Basler, K.2
-
10
-
-
0033194243
-
Mammalian Suppressor-of-Fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman P, et al. (1999) Mammalian Suppressor-of-Fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat Cell Biol 1(5):312-319.
-
(1999)
Nat Cell Biol
, vol.1
, Issue.5
, pp. 312-319
-
-
Kogerman, P.1
-
11
-
-
0034669178
-
Interactions with Costal2 and Suppressor of fused regulate nuclear translocation and activity of Cubitus interruptus
-
Wang G, Amanai K, Wang B, Jiang J (2000) Interactions with Costal2 and Suppressor of fused regulate nuclear translocation and activity of Cubitus interruptus. Genes Dev 14(22):2893-2905.
-
(2000)
Genes Dev
, vol.14
, Issue.22
, pp. 2893-2905
-
-
Wang, G.1
Amanai, K.2
Wang, B.3
Jiang, J.4
-
12
-
-
0038813753
-
Characterization of the physical interaction of Gli proteins with SUFU proteins
-
Dunaeva M, Michelson P, Kogerman P, Toftgard R (2003) Characterization of the physical interaction of Gli proteins with SUFU proteins. J Biol Chem 278(7):5116-5122.
-
(2003)
J Biol Chem
, vol.278
, Issue.7
, pp. 5116-5122
-
-
Dunaeva, M.1
Michelson, P.2
Kogerman, P.3
Toftgard, R.4
-
13
-
-
84896861295
-
Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapß2 in Hedgehog signaling
-
Shi Q, Han Y, Jiang J (2014) Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapß2 in Hedgehog signaling. J Cell Sci 127(Pt 5):1092-1103.
-
(2014)
J Cell Sci
, vol.127
, Issue.5
, pp. 1092-1103
-
-
Shi, Q.1
Han, Y.2
Jiang, J.3
-
14
-
-
84904117579
-
Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization
-
Szczepny A, et al. (2014) Overlapping binding sites for importin β1 and suppressor of fused (SuFu) on glioma-associated oncogene homologue 1 (Gli1) regulate its nuclear localization. Biochem J 461(3):469-476.
-
(2014)
Biochem J
, vol.461
, Issue.3
, pp. 469-476
-
-
Szczepny, A.1
-
15
-
-
68249125941
-
Sufu recruits GSK3beta for efficient processing of Gli3
-
Kise Y, Morinaka A, Teglund S, Miki H (2009) Sufu recruits GSK3beta for efficient processing of Gli3. Biochem Biophys Res Commun 387(3):569-574.
-
(2009)
Biochem Biophys Res Commun
, vol.387
, Issue.3
, pp. 569-574
-
-
Kise, Y.1
Morinaka, A.2
Teglund, S.3
Miki, H.4
-
16
-
-
77950463564
-
The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
-
Humke EW, Dorn KV, Milenkovic L, Scott MP, Rohatgi R (2010) The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins. Genes Dev 24(7):670-682.
-
(2010)
Genes Dev
, vol.24
, Issue.7
, pp. 670-682
-
-
Humke, E.W.1
Dorn, K.V.2
Milenkovic, L.3
Scott, M.P.4
Rohatgi, R.5
-
17
-
-
69249245332
-
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
-
Chen MH, et al. (2009) Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev 23(16):1910-1928.
-
(2009)
Genes Dev
, vol.23
, Issue.16
, pp. 1910-1928
-
-
Chen, M.H.1
-
18
-
-
13344261322
-
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus
-
Zhang W, et al. (2005) Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell 8(2):267-278.
-
(2005)
Dev Cell
, vol.8
, Issue.2
, pp. 267-278
-
-
Zhang, W.1
-
19
-
-
1942518275
-
Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms
-
Wang G, Jiang J (2004) Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms. Dev Biol 268(2):493-505.
-
(2004)
Dev Biol
, vol.268
, Issue.2
, pp. 493-505
-
-
Wang, G.1
Jiang, J.2
-
20
-
-
31744450041
-
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms
-
Barnfield PC, Zhang X, Thanabalasingham V, Yoshida M, Hui CC (2005) Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms. Differentiation 73(8):397-405.
-
(2005)
Differentiation
, vol.73
, Issue.8
, pp. 397-405
-
-
Barnfield, P.C.1
Zhang, X.2
Thanabalasingham, V.3
Yoshida, M.4
Hui, C.C.5
-
21
-
-
0242624640
-
Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis
-
Fouix S, et al. (2003) Over-expression of a novel nuclear interactor of Suppressor of fused, the Drosophila myelodysplasia/myeloid leukaemia factor, induces abnormal morphogenesis associated with increased apoptosis and DNA synthesis. Genes Cells 8(11):897-911.
-
(2003)
Genes Cells
, vol.8
, Issue.11
, pp. 897-911
-
-
Fouix, S.1
-
22
-
-
0037117611
-
Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex
-
Cheng SY, Bishop JM (2002) Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex. Proc Natl Acad Sci USA 99(8):5442-5447.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.8
, pp. 5442-5447
-
-
Cheng, S.Y.1
Bishop, J.M.2
-
23
-
-
0032492995
-
Suppressor of fused links fused and Cubitus interruptus on the Hedgehog signalling pathway
-
Monnier V, Dussillol F, Alves G, Lamour-Isnard C, Plessis A (1998) Suppressor of fused links fused and Cubitus interruptus on the Hedgehog signalling pathway. Curr Biol 8(10):583-586.
-
(1998)
Curr Biol
, vol.8
, Issue.10
, pp. 583-586
-
-
Monnier, V.1
Dussillol, F.2
Alves, G.3
Lamour-Isnard, C.4
Plessis, A.5
-
24
-
-
0033789068
-
Suppressor of fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus
-
Méthot N, Basler K (2000) Suppressor of fused opposes Hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. Development 127(18):4001-4010.
-
(2000)
Development
, vol.127
, Issue.18
, pp. 4001-4010
-
-
Méthot, N.1
Basler, K.2
-
25
-
-
0032728958
-
Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus
-
Wang G, Wang B, Jiang J (1999) Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus. Genes Dev 13(21):2828-2837.
-
(1999)
Genes Dev
, vol.13
, Issue.21
, pp. 2828-2837
-
-
Wang, G.1
Wang, B.2
Jiang, J.3
-
26
-
-
84887702556
-
Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci
-
Zhang Y, et al. (2013) Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci. Nat Commun 4:2608.
-
(2013)
Nat Commun
, vol.4
, pp. 2608
-
-
Zhang, Y.1
-
27
-
-
84889832303
-
Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation
-
Cherry AL, et al. (2013) Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation. Acta Crystallogr D Biol Crystallogr 69(Pt 12):2563-2579.
-
(2013)
Acta Crystallogr D Biol Crystallogr
, vol.69
, Issue.12
, pp. 2563-2579
-
-
Cherry, A.L.1
-
28
-
-
33847660443
-
An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases
-
Bischof J, Maeda RK, Hediger M, Karch F, Basler K (2007) An optimized transgenesis system for Drosophila using germ-line-specific phiC31 integrases. Proc Natl Acad Sci USA 104(9):3312-3317.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.9
, pp. 3312-3317
-
-
Bischof, J.1
Maeda, R.K.2
Hediger, M.3
Karch, F.4
Basler, K.5
-
29
-
-
33646893705
-
A Hedgehog-induced BTB protein modulates Hedgehog signaling by degrading Ci/Gli transcription factor
-
Zhang Q, et al. (2006) A Hedgehog-induced BTB protein modulates Hedgehog signaling by degrading Ci/Gli transcription factor. Dev Cell 10(6):719-729.
-
(2006)
Dev Cell
, vol.10
, Issue.6
, pp. 719-729
-
-
Zhang, Q.1
-
30
-
-
0033859849
-
Nuclear import of Cubitus interruptus is regulated by Hedgehog via a mechanism distinct from Ci stabilization and Ci activation
-
Wang QT, Holmgren RA (2000) Nuclear import of Cubitus interruptus is regulated by Hedgehog via a mechanism distinct from Ci stabilization and Ci activation. Development 127(14):3131-3139.
-
(2000)
Development
, vol.127
, Issue.14
, pp. 3131-3139
-
-
Wang, Q.T.1
Holmgren, R.A.2
-
31
-
-
78650751460
-
Inhibition of the nuclear import of Cubitus interruptus by Roadkill in the presence of strong Hedgehog signal
-
Seong KH, et al. (2010) Inhibition of the nuclear import of Cubitus interruptus by Roadkill in the presence of strong Hedgehog signal. PLoS ONE 5(12):e15365.
-
(2010)
PLoS ONE
, vol.5
, Issue.12
, pp. e15365
-
-
Seong, K.H.1
-
32
-
-
0030901264
-
Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling
-
Akimaru H, et al. (1997) Drosophila CBP is a co-activator of cubitus interruptus in hedgehog signalling. Nature 386(6626):735-738.
-
(1997)
Nature
, vol.386
, Issue.6626
, pp. 735-738
-
-
Akimaru, H.1
-
33
-
-
33645006077
-
Regulation of the Drosophila transcription factor, Cubitus interruptus, by two conserved domains
-
Croker JA, Ziegenhorn SL, Holmgren RA (2006) Regulation of the Drosophila transcription factor, Cubitus interruptus, by two conserved domains. Dev Biol 291(2):368-381.
-
(2006)
Dev Biol
, vol.291
, Issue.2
, pp. 368-381
-
-
Croker, J.A.1
Ziegenhorn, S.L.2
Holmgren, R.A.3
-
34
-
-
4544353067
-
Suppressor of fused regulates Gli activity through a dual binding mechanism
-
Merchant M, et al. (2004) Suppressor of fused regulates Gli activity through a dual binding mechanism. Mol Cell Biol 24(19):8627-8641.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.19
, pp. 8627-8641
-
-
Merchant, M.1
-
35
-
-
0033583035
-
Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3
-
Dai P, et al. (1999) Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3. J Biol Chem 274(12):8143-8152.
-
(1999)
J Biol Chem
, vol.274
, Issue.12
, pp. 8143-8152
-
-
Dai, P.1
-
36
-
-
33845219533
-
Mediator modulates Gli3-dependent Sonic hedgehog signaling
-
Zhou H, Kim S, Ishii S, Boyer TG (2006) Mediator modulates Gli3-dependent Sonic hedgehog signaling. Mol Cell Biol 26(23):8667-8682.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.23
, pp. 8667-8682
-
-
Zhou, H.1
Kim, S.2
Ishii, S.3
Boyer, T.G.4
-
37
-
-
80054022786
-
Gli proteins in development and disease
-
Hui CC, Angers S (2011) Gli proteins in development and disease. Annu Rev Cell Dev Biol 27:513-537.
-
(2011)
Annu Rev Cell Dev Biol
, vol.27
, pp. 513-537
-
-
Hui, C.C.1
Angers, S.2
-
38
-
-
84910677833
-
Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling
-
Lin C, et al. (2014) Regulation of Sufu activity by p66β and Mycbp provides new insight into vertebrate Hedgehog signaling. Genes Dev 28(22):2547-2563.
-
(2014)
Genes Dev
, vol.28
, Issue.22
, pp. 2547-2563
-
-
Lin, C.1
|