Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injury

Journal of Biological Chemistry

Volumn 290, Issue 18, 2015, Pages 11704-11714

  Jiang, Bijie ^a,b   Shen, Hong ^b   Chen, Zheng ^b   Yin, Lei ^b   Zan, Linsen ^a   Rui, Liangyou ^b  

^a NORTHWEST A F UNIVERSITY   (China)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY;

CARBOXYL TERMINUS; CO-EXPRESSION; LIVER INJURIES; OVER-EXPRESSION; UBIQUITINATION;

BIOLOGY;

ALANINE AMINOTRANSFERASE; BILIRUBIN; CARBOXY TERMINAL OF HSC70 INTERACTING PROTEIN; HEAT SHOCK COGNATE PROTEIN 70; NUCLEAR FACTOR KAPPA B INDUCING KINASE; PROTEIN SERINE THREONINE KINASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 3; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CHIP PROTEIN, MOUSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NF-KAPPA B KINASE; PROTEASOME; STUB1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME REGULATION; ENZYME STABILITY; HEPATITIS; LIVER INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TETRATRICOPEPTIDE REPEAT; UBIQUITINATION; ANIMAL; CHEMISTRY; CYTOLOGY; ENZYME ACTIVATION; HEK293 CELL LINE; HUMAN; INJURIES; LIVER; LIVER CELL; METABOLISM; PROTEIN DEGRADATION; PROTEIN TERTIARY STRUCTURE;

ANIMALS; DOWN-REGULATION; ENZYME ACTIVATION; HEK293 CELLS; HEPATOCYTES; HUMANS; LIVER; MALE; MICE; NF-KAPPA B P52 SUBUNIT; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; TNF RECEPTOR-ASSOCIATED FACTOR 3; UBIQUITIN-PROTEIN LIGASES;

EID: 84929493032     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.635086     Document Type: Article

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