The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15996-16006

  Ahmed, Syed Feroj ^a   Deb, Satamita ^a,b   Paul, Indranil ^a   Chatterjee, Anirban ^a   Mandal, Tapashi ^a   Chatterjee, Uttara ^b   Ghosh, Mrinal K ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

^b INSTITUTE OF POST GRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; CELLULAR PROCESS; COMPLEX MODES; DEGRADATION PATHWAYS; DOWN-REGULATION; E3 LIGASE; HUMAN PROSTATE CANCER; INVERSE CORRELATION; MOLECULAR CHAPERONES; N-TERMINAL DOMAINS; OVER-EXPRESSION; PROTEASOMAL DEGRADATION; TUMOR SUPPRESSORS; UBIQUITIN-PROTEASOME SYSTEM; UBIQUITINATION;

DISEASES;

DEGRADATION;

AMINO TERMINAL TELOPEPTIDE; CARBOXY TERMINAL SEQUENCE OF HEAT SHOCK COGNATE PROTEIN 70 INTERACTING PROTEIN; CARBOXY TERMINAL TELOPEPTIDE; CHAPERONE; HEAT SHOCK COGNATE PROTEIN 70; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME REGULATION; GENE SEQUENCE; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; UBIQUITINATION;

CELL LINE, TUMOR; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEOLYSIS; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84860874770     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.321083     Document Type: Article

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