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Volumn 5, Issue 7, 2014, Pages 1969-1986

CHIP is a novel tumor suppressor in pancreatic cancer through targeting EGFR

Author keywords

CHIP; EGFR; Pancreatic cancer; Ubiquitination

Indexed keywords

CARBOXYL TERMINUS OF HEAT SHOCK PROTEIN 70 INTERACTING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; KI 67 ANTIGEN; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; STUB1 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE;

EID: 84898961547     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1890     Document Type: Article
Times cited : (64)

References (33)
  • 5
    • 0035256698 scopus 로고    scopus 로고
    • Untangling the ErbB signalling network
    • Yarden Y and Sliwkowski MX. Untangling the ErbB signalling network. Nat Rev Mol Cell Biol. 2001; 2(2):127- 137.
    • (2001) Nat Rev Mol Cell Biol. , vol.2 , Issue.2 , pp. 127-137
    • Yarden, Y.1    Sliwkowski, M.X.2
  • 7
    • 34250828460 scopus 로고    scopus 로고
    • Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response
    • Tzeng CW, Frolov A, Frolova N, Jhala NC, Howard JH, Vickers SM, Buchsbaum DJ, Heslin MJ and Arnoletti JP. Pancreatic cancer epidermal growth factor receptor (EGFR) intron 1 polymorphism influences postoperative patient survival and in vitro erlotinib response. Ann Surg Oncol. 2007; 14(7):2150-2158.
    • (2007) Ann Surg Oncol. , vol.14 , Issue.7 , pp. 2150-2158
    • Tzeng, C.W.1    Frolov, A.2    Frolova, N.3    Jhala, N.C.4    Howard, J.H.5    Vickers, S.M.6    Buchsbaum, D.J.7    Heslin, M.J.8    Arnoletti, J.P.9
  • 13
    • 84874658997 scopus 로고    scopus 로고
    • CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer
    • Wang S, Wu X, Zhang J, Chen Y, Xu J, Xia X, He S, Qiang F, Li A, Shu Y, Roe OD, Li G and Zhou JW. CHIP functions as a novel suppressor of tumour angiogenesis with prognostic significance in human gastric cancer. Gut. 2013; 62(4):496-508.
    • (2013) Gut. , vol.62 , Issue.4 , pp. 496-508
    • Wang, S.1    Wu, X.2    Zhang, J.3    Chen, Y.4    Xu, J.5    Xia, X.6    He, S.7    Qiang, F.8    Li, A.9    Shu, Y.10    Roe, O.D.11    Li, G.12    Zhou, J.W.13
  • 14
    • 80051469504 scopus 로고    scopus 로고
    • Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase
    • Su CH, Wang CY, Lan KH, Li CP, Chao Y, Lin HC, Lee SD and Lee WP. Akt phosphorylation at Thr308 and Ser473 is required for CHIP-mediated ubiquitination of the kinase. Cell Signal. 2011; 23(11):1824-1830.
    • (2011) Cell Signal. , vol.23 , Issue.11 , pp. 1824-1830
    • Su, C.H.1    Wang, C.Y.2    Lan, K.H.3    Li, C.P.4    Chao, Y.5    Lin, H.C.6    Lee, S.D.7    Lee, W.P.8
  • 15
    • 84860874770 scopus 로고    scopus 로고
    • The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation
    • Ahmed SF, Deb S, Paul I, Chatterjee A, Mandal T, Chatterjee U and Ghosh MK. The chaperone-assisted E3 ligase C terminus of Hsc70-interacting protein (CHIP) targets PTEN for proteasomal degradation. J Biol Chem. 2012; 287(19):15996-16006.
    • (2012) J Biol Chem. , vol.287 , Issue.19 , pp. 15996-16006
    • Ahmed, S.F.1    Deb, S.2    Paul, I.3    Chatterjee, A.4    Mandal, T.5    Chatterjee, U.6    Ghosh, M.K.7
  • 16
    • 22844447871 scopus 로고    scopus 로고
    • The chaperoneassociated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation
    • Esser C, Scheffner M and Hohfeld J. The chaperoneassociated ubiquitin ligase CHIP is able to target p53 for proteasomal degradation. J Biol Chem. 2005; 280(29):27443-27448.
    • (2005) J Biol Chem. , vol.280 , Issue.29 , pp. 27443-27448
    • Esser, C.1    Scheffner, M.2    Hohfeld, J.3
  • 17
    • 42549144964 scopus 로고    scopus 로고
    • Expression of EGF and EGFR strongly correlates with metastasis of pancreatic ductal carcinoma
    • Pryczynicz A, Guzinska-Ustymowicz K, Kemona A and Czyzewska J. Expression of EGF and EGFR strongly correlates with metastasis of pancreatic ductal carcinoma. Anticancer Res. 2008; 28(2B):1399-1404.
    • (2008) Anticancer Res. , vol.28 B , Issue.2 , pp. 1399-1404
    • Pryczynicz, A.1    Guzinska-Ustymowicz, K.2    Kemona, A.3    Czyzewska, J.4
  • 21
    • 0036789884 scopus 로고    scopus 로고
    • Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu
    • Xu W, Marcu M, Yuan X, Mimnaugh E, Patterson C and Neckers L. Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu. Proc Natl Acad Sci U S A. 2002; 99(20):12847-12852.
    • (2002) Proc Natl Acad Sci U S A. , vol.99 , Issue.20 , pp. 12847-12852
    • Xu, W.1    Marcu, M.2    Yuan, X.3    Mimnaugh, E.4    Patterson, C.5    Neckers, L.6
  • 22
    • 0036135151 scopus 로고    scopus 로고
    • Role of Akt in growth and survival of PANC-1 pancreatic cancer cells
    • Yao Z, Okabayashi Y, Yutsudo Y, Kitamura T, Ogawa W and Kasuga M. Role of Akt in growth and survival of PANC-1 pancreatic cancer cells. Pancreas. 2002; 24(1):42- 46.
    • (2002) Pancreas. , vol.24 , Issue.1 , pp. 42-46
    • Yao, Z.1    Okabayashi, Y.2    Yutsudo, Y.3    Kitamura, T.4    Ogawa, W.5    Kasuga, M.6
  • 23
    • 33644647192 scopus 로고    scopus 로고
    • Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model
    • Trevino JG, Summy JM, Lesslie DP, Parikh NU, Hong DS, Lee FY, Donato NJ, Abbruzzese JL, Baker CH and Gallick GE. Inhibition of SRC expression and activity inhibits tumor progression and metastasis of human pancreatic adenocarcinoma cells in an orthotopic nude mouse model. Am J Pathol. 2006; 168(3):962-972.
    • (2006) Am J Pathol. , vol.168 , Issue.3 , pp. 962-972
    • Trevino, J.G.1    Summy, J.M.2    Lesslie, D.P.3    Parikh, N.U.4    Hong, D.S.5    Lee, F.Y.6    Donato, N.J.7    Abbruzzese, J.L.8    Baker, C.H.9    Gallick, G.E.10
  • 24
    • 0029787957 scopus 로고    scopus 로고
    • An effect of K-ras gene mutation on epidermal growth factor receptor signal transduction in PANC-1 pancreatic carcinoma cells
    • Watanabe M, Nobuta A, Tanaka J and Asaka M. An effect of K-ras gene mutation on epidermal growth factor receptor signal transduction in PANC-1 pancreatic carcinoma cells. Int J Cancer. 1996; 67(2):264-268.
    • (1996) Int J Cancer. , vol.67 , Issue.2 , pp. 264-268
    • Watanabe, M.1    Nobuta, A.2    Tanaka, J.3    Asaka, M.4
  • 25
    • 0034651872 scopus 로고    scopus 로고
    • An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity
    • Goi T, Shipitsin M, Lu Z, Foster DA, Klinz SG and Feig LA. An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity. EMBO J. 2000; 19(4):623-630.
    • (2000) EMBO J. , vol.19 , Issue.4 , pp. 623-630
    • Goi, T.1    Shipitsin, M.2    Lu, Z.3    Foster, D.A.4    Klinz, S.G.5    Feig, L.A.6
  • 26
    • 0345138451 scopus 로고    scopus 로고
    • Functional implication of the interaction between EGF receptor and c-Src
    • Leu TH and Maa MC. Functional implication of the interaction between EGF receptor and c-Src. Front Biosci. 2003; 8:s28-38.
    • (2003) Front Biosci. , vol.8
    • Leu, T.H.1    Maa, M.C.2
  • 27
    • 0029861248 scopus 로고    scopus 로고
    • Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor
    • Rojas M, Yao S and Lin YZ. Controlling epidermal growth factor (EGF)-stimulated Ras activation in intact cells by a cell-permeable peptide mimicking phosphorylated EGF receptor. J Biol Chem. 1996; 271(44):27456-27461.
    • (1996) J Biol Chem. , vol.271 , Issue.44 , pp. 27456-27461
    • Rojas, M.1    Yao, S.2    Lin, Y.Z.3
  • 28
    • 79954930813 scopus 로고    scopus 로고
    • Carboxyl terminus of Hsp70- interacting protein (CHIP) contributes to human glioma oncogenesis
    • Xu T, Zhou Q, Zhou J, Huang Y, Yan Y, Li W, Wang C, Hu G, Lu Y and Chen J. Carboxyl terminus of Hsp70- interacting protein (CHIP) contributes to human glioma oncogenesis. Cancer Sci. 2011; 102(5):959-966.
    • (2011) Cancer Sci. , vol.102 , Issue.5 , pp. 959-966
    • Xu, T.1    Zhou, Q.2    Zhou, J.3    Huang, Y.4    Yan, Y.5    Li, W.6    Wang, C.7    Hu, G.8    Lu, Y.9    Chen, J.10
  • 29
    • 64849086030 scopus 로고    scopus 로고
    • Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line
    • Lu YY, Jing DD, Xu M, Wu K and Wang XP. Anti-tumor activity of erlotinib in the BxPC-3 pancreatic cancer cell line. World J Gastroenterol. 2008; 14(35):5403-5411.
    • (2008) World J Gastroenterol. , vol.14 , Issue.35 , pp. 5403-5411
    • Lu, Y.Y.1    Jing, D.D.2    Xu, M.3    Wu, K.4    Wang, X.P.5
  • 30
    • 52649108603 scopus 로고    scopus 로고
    • The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer
    • Morgan MA, Parsels LA, Kollar LE, Normolle DP, Maybaum J and Lawrence TS. The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer. Clin Cancer Res. 2008; 14(16):5142-5149.
    • (2008) Clin Cancer Res. , vol.14 , Issue.16 , pp. 5142-5149
    • Morgan, M.A.1    Parsels, L.A.2    Kollar, L.E.3    Normolle, D.P.4    Maybaum, J.5    Lawrence, T.S.6
  • 32
    • 84880051618 scopus 로고    scopus 로고
    • Metastatic Lymph Node CHIP Expression is a Potential Prognostic Marker for Resected Esophageal Squamous Cell Carcinoma Patients
    • Wen J, Luo KJ, Hu Y, Yang H and Fu JH. Metastatic Lymph Node CHIP Expression is a Potential Prognostic Marker for Resected Esophageal Squamous Cell Carcinoma Patients. Ann Surg Oncol. 2013.
    • (2013) Ann Surg Oncol
    • Wen, J.1    Luo, K.J.2    Hu, Y.3    Yang, H.4    Fu, J.H.5
  • 33
    • 84872694294 scopus 로고    scopus 로고
    • Expression of carboxyl terminus of Hsp70-interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma
    • Liang ZL, Kim M, Huang SM, Lee HJ and Kim JM. Expression of carboxyl terminus of Hsp70-interacting protein (CHIP) indicates poor prognosis in human gallbladder carcinoma. Oncol Lett. 2013; 5(3):813-818.
    • (2013) Oncol Lett. , vol.5 , Issue.3 , pp. 813-818
    • Liang, Z.L.1    Kim, M.2    Huang, S.M.3    Lee, H.J.4    Kim, J.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.