-
1
-
-
84905175079
-
Energy metabolism in the liver
-
Rui L. Energy metabolism in the liver. Compr Physiol 2014;4:177-197.
-
(2014)
Compr Physiol
, vol.4
, pp. 177-197
-
-
Rui, L.1
-
2
-
-
61749099391
-
Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome
-
Imaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, et al. Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest 2009;119:305-314.
-
(2009)
J Clin Invest
, vol.119
, pp. 305-314
-
-
Imaeda, A.B.1
Watanabe, A.2
Sohail, M.A.3
Mahmood, S.4
Mohamadnejad, M.5
Sutterwala, F.S.6
-
3
-
-
84859708101
-
The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation
-
McGill MR, Sharpe MR, Williams CD, Taha M, Curry SC, Jaeschke H. The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. J Clin Invest 2012;122:1574-1583.
-
(2012)
J Clin Invest
, vol.122
, pp. 1574-1583
-
-
McGill, M.R.1
Sharpe, M.R.2
Williams, C.D.3
Taha, M.4
Curry, S.C.5
Jaeschke, H.6
-
4
-
-
20244373939
-
The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion
-
Tsung A, Sahai R, Tanaka H, Nakao A, Fink MP, Lotze MT, et al. The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion. J Exp Med 2005;201:1135-1143.
-
(2005)
J Exp Med
, vol.201
, pp. 1135-1143
-
-
Tsung, A.1
Sahai, R.2
Tanaka, H.3
Nakao, A.4
Fink, M.P.5
Lotze, M.T.6
-
5
-
-
84887005701
-
Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice
-
Sheng L, Jiang B, Rui L. Intracellular lipid content is a key intrinsic determinant for hepatocyte viability and metabolic and inflammatory states in mice. Am J Physiol Endocrinol Metab 2013;305:E1115-1123.
-
(2013)
Am J Physiol Endocrinol Metab
, vol.305
, pp. E1115-E1123
-
-
Sheng, L.1
Jiang, B.2
Rui, L.3
-
6
-
-
84862777838
-
Interleukin-30: a novel antiinflammatory cytokine candidate for prevention and treatment of inflammatory cytokine-induced liver injury
-
Dibra D, Cutrera J, Xia X, Kallakury B, Mishra L, Li S. Interleukin-30: a novel antiinflammatory cytokine candidate for prevention and treatment of inflammatory cytokine-induced liver injury. Hepatology 2012;55:1204-1214.
-
(2012)
Hepatology
, vol.55
, pp. 1204-1214
-
-
Dibra, D.1
Cutrera, J.2
Xia, X.3
Kallakury, B.4
Mishra, L.5
Li, S.6
-
7
-
-
84856070851
-
Interleukin-11 links oxidative stress and compensatory proliferation
-
Nishina T, Komazawa-Sakon S, Yanaka S, Piao X, Zheng DM, Piao JH, et al. Interleukin-11 links oxidative stress and compensatory proliferation. Sci Signal 2012;5:ra5.
-
(2012)
Sci Signal
, vol.5
, pp. ra5
-
-
Nishina, T.1
Komazawa-Sakon, S.2
Yanaka, S.3
Piao, X.4
Zheng, D.M.5
Piao, J.H.6
-
8
-
-
84862000588
-
NF-kappaB-inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action
-
Sheng L, Zhou Y, Chen Z, Ren D, Cho KW, Jiang L, et al. NF-kappaB-inducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action. Nat Med 2012;18:943-949.
-
(2012)
Nat Med
, vol.18
, pp. 943-949
-
-
Sheng, L.1
Zhou, Y.2
Chen, Z.3
Ren, D.4
Cho, K.W.5
Jiang, L.6
-
9
-
-
46749111541
-
Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells
-
Saitoh Y, Yamamoto N, Dewan MZ, Sugimoto H, Martinez Bruyn VJ, Iwasaki Y, et al. Overexpressed NF-kappaB-inducing kinase contributes to the tumorigenesis of adult T-cell leukemia and Hodgkin Reed-Sternberg cells. Blood 2008;111:5118-5129.
-
(2008)
Blood
, vol.111
, pp. 5118-5129
-
-
Saitoh, Y.1
Yamamoto, N.2
Dewan, M.Z.3
Sugimoto, H.4
Martinez Bruyn, V.J.5
Iwasaki, Y.6
-
10
-
-
2942731516
-
Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
-
Liao G, Zhang M, Harhaj EW, Sun SC. Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J Biol Chem 2004;279:26243-26250.
-
(2004)
J Biol Chem
, vol.279
, pp. 26243-26250
-
-
Liao, G.1
Zhang, M.2
Harhaj, E.W.3
Sun, S.C.4
-
11
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
Varfolomeev E, Blankenship JW, Wayson SM, Fedorova AV, Kayagaki N, Garg P, et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007;131:669-681.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
-
12
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince JE, Wong WW, Khan N, Feltham R, Chau D, Ahmed AU, et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007;131:682-693.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
-
13
-
-
78650920066
-
Non-canonical NF-kappaB signaling pathway
-
Sun SC. Non-canonical NF-kappaB signaling pathway. Cell Res 2011;21:71-85.
-
(2011)
Cell Res
, vol.21
, pp. 71-85
-
-
Sun, S.C.1
-
14
-
-
77956407149
-
NF-kappaB inducing kinase: a key regulator in the immune system and in cancer
-
Thu YM, Richmond A. NF-kappaB inducing kinase: a key regulator in the immune system and in cancer. Cytokine Growth Factor Rev 2010;21:213-226.
-
(2010)
Cytokine Growth Factor Rev
, vol.21
, pp. 213-226
-
-
Thu, Y.M.1
Richmond, A.2
-
15
-
-
0035937845
-
The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome
-
Habib AA, Chatterjee S, Park SK, Ratan RR, Lefebvre S, Vartanian T. The epidermal growth factor receptor engages receptor interacting protein and nuclear factor-kappa B (NF-kappa B)-inducing kinase to activate NF-kappa B. Identification of a novel receptor-tyrosine kinase signalosome. J Biol Chem 2001;276:8865-8874.
-
(2001)
J Biol Chem
, vol.276
, pp. 8865-8874
-
-
Habib, A.A.1
Chatterjee, S.2
Park, S.K.3
Ratan, R.R.4
Lefebvre, S.5
Vartanian, T.6
-
16
-
-
65549146416
-
Role of Src signal transduction pathways in scatter factor-mediated cellular protection
-
Fan S, Meng Q, Laterra JJ, Rosen EM. Role of Src signal transduction pathways in scatter factor-mediated cellular protection. J Biol Chem 2009;284:7561-7577.
-
(2009)
J Biol Chem
, vol.284
, pp. 7561-7577
-
-
Fan, S.1
Meng, Q.2
Laterra, J.J.3
Rosen, E.M.4
-
17
-
-
0034193305
-
Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system
-
Fagarasan S, Shinkura R, Kamata T, Nogaki F, Ikuta K, Tashiro K, et al. Alymphoplasia (aly)-type nuclear factor kappaB-inducing kinase (NIK) causes defects in secondary lymphoid tissue chemokine receptor signaling and homing of peritoneal cells to the gut-associated lymphatic tissue system. J Exp Med 2000;191:1477-1486.
-
(2000)
J Exp Med
, vol.191
, pp. 1477-1486
-
-
Fagarasan, S.1
Shinkura, R.2
Kamata, T.3
Nogaki, F.4
Ikuta, K.5
Tashiro, K.6
-
18
-
-
33745855826
-
NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha
-
Park GY, Wang X, Hu N, Pedchenko TV, Blackwell TS, Christman JW. NIK is involved in nucleosomal regulation by enhancing histone H3 phosphorylation by IKKalpha. J Biol Chem 2006;281:18684-18690.
-
(2006)
J Biol Chem
, vol.281
, pp. 18684-18690
-
-
Park, G.Y.1
Wang, X.2
Hu, N.3
Pedchenko, T.V.4
Blackwell, T.S.5
Christman, J.W.6
-
19
-
-
56349164239
-
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
-
Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, et al. Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol 2008;9:1371-1378.
-
(2008)
Nat Immunol
, vol.9
, pp. 1371-1378
-
-
Zarnegar, B.J.1
Wang, Y.2
Mahoney, D.J.3
Dempsey, P.W.4
Cheung, H.H.5
He, J.6
-
20
-
-
56349164232
-
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling
-
Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, et al. Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling. Nat Immunol 2008;9:1364-1370.
-
(2008)
Nat Immunol
, vol.9
, pp. 1364-1370
-
-
Vallabhapurapu, S.1
Matsuzawa, A.2
Zhang, W.3
Tseng, P.H.4
Keats, J.J.5
Wang, H.6
-
21
-
-
0034745420
-
NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100
-
Xiao G, Harhaj EW, Sun SC. NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100. Mol Cell 2001;7:401-409.
-
(2001)
Mol Cell
, vol.7
, pp. 401-409
-
-
Xiao, G.1
Harhaj, E.W.2
Sun, S.C.3
-
22
-
-
17944378526
-
Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway
-
Senftleben U, Cao Y, Xiao G, Greten FR, Krahn G, Bonizzi G, et al. Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway. Science 2001;293:1495-1499.
-
(2001)
Science
, vol.293
, pp. 1495-1499
-
-
Senftleben, U.1
Cao, Y.2
Xiao, G.3
Greten, F.R.4
Krahn, G.5
Bonizzi, G.6
-
23
-
-
3142663912
-
Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation
-
Xiao G, Fong A, Sun SC. Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation. J Biol Chem 2004;279:30099-30105.
-
(2004)
J Biol Chem
, vol.279
, pp. 30099-30105
-
-
Xiao, G.1
Fong, A.2
Sun, S.C.3
-
24
-
-
49449098218
-
NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells
-
Sasaki Y, Calado DP, Derudder E, Zhang B, Shimizu Y, Mackay F, et al. NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells. Proc Natl Acad Sci U S A 2008;105:10883-10888.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 10883-10888
-
-
Sasaki, Y.1
Calado, D.P.2
Derudder, E.3
Zhang, B.4
Shimizu, Y.5
Mackay, F.6
-
25
-
-
0033146933
-
Gadolinium chloride-induced Kupffer cell blockade increases uptake of oxidized low-density lipoproteins by rat heart and aorta
-
Usynin IF, Khar'kovsky AV, Balitskaya NI, Panin LE. Gadolinium chloride-induced Kupffer cell blockade increases uptake of oxidized low-density lipoproteins by rat heart and aorta. Biochemistry (Mosc) 1999;64:620-624.
-
(1999)
Biochemistry (Mosc)
, vol.64
, pp. 620-624
-
-
Usynin, I.F.1
Khar'kovsky, A.V.2
Balitskaya, N.I.3
Panin, L.E.4
-
26
-
-
77449117735
-
Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance
-
Huang W, Metlakunta A, Dedousis N, Zhang P, Sipula I, Dube JJ, et al. Depletion of liver Kupffer cells prevents the development of diet-induced hepatic steatosis and insulin resistance. Diabetes 2010;59:347-357.
-
(2010)
Diabetes
, vol.59
, pp. 347-357
-
-
Huang, W.1
Metlakunta, A.2
Dedousis, N.3
Zhang, P.4
Sipula, I.5
Dube, J.J.6
-
27
-
-
77956412905
-
Cytoskeletal keratin glycosylation protects epithelial tissue from injury
-
Ku NO, Toivola DM, Strnad P, Omary MB. Cytoskeletal keratin glycosylation protects epithelial tissue from injury. Nat Cell Biol 2010;12:876-885.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 876-885
-
-
Ku, N.O.1
Toivola, D.M.2
Strnad, P.3
Omary, M.B.4
-
28
-
-
0032930861
-
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase
-
Shinkura R, Kitada K, Matsuda F, Tashiro K, Ikuta K, Suzuki M, et al. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase. Nat Genet 1999;22:74-77.
-
(1999)
Nat Genet
, vol.22
, pp. 74-77
-
-
Shinkura, R.1
Kitada, K.2
Matsuda, F.3
Tashiro, K.4
Ikuta, K.5
Suzuki, M.6
-
29
-
-
84865536932
-
Hepatic activation of IKK/NFkappaB signaling induces liver fibrosis via macrophage-mediated chronic inflammation
-
Sunami Y, Leithauser F, Gul S, Fiedler K, Guldiken N, Espenlaub S, et al. Hepatic activation of IKK/NFkappaB signaling induces liver fibrosis via macrophage-mediated chronic inflammation. Hepatology 2012;56:1117-1128.
-
(2012)
Hepatology
, vol.56
, pp. 1117-1128
-
-
Sunami, Y.1
Leithauser, F.2
Gul, S.3
Fiedler, K.4
Guldiken, N.5
Espenlaub, S.6
-
30
-
-
85047690577
-
NF-kappaB inducing kinase activates NF-kappaB transcriptional activity independently of IkappaB kinase gamma through a p38 MAPK-dependent RelA phosphorylation pathway
-
Jijon H, Allard B, Jobin C. NF-kappaB inducing kinase activates NF-kappaB transcriptional activity independently of IkappaB kinase gamma through a p38 MAPK-dependent RelA phosphorylation pathway. Cell Signal 2004;16:1023-1032.
-
(2004)
Cell Signal
, vol.16
, pp. 1023-1032
-
-
Jijon, H.1
Allard, B.2
Jobin, C.3
|