IP3 3-kinase B controls hematopoietic stem cell homeostasis and prevents lethal hematopoietic failure in mice

Blood

Volumn 125, Issue 18, 2015, Pages 2786-2797

  Siegemund, Sabine ^a   Rigaud, Stephanie ^a   Conche, Claire ^a   Broaten, Blake ^a   Schaffer, Lana ^a   Westernberg, Luise ^a   Head, Steven Robert ^a   Sauer, Karsten ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL TRISPHOSPHATE 3 KINASE; INOSITOL TRISPHOSPHATE 3 KINASE B; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; STEM CELL FACTOR; TRANSCRIPTOME; UNCLASSIFIED DRUG; INOSITOL 1,4,5-TRISPHOSPHATE 3-KINASE; PHOSPHOTRANSFERASE;

ADULT; AEROBIC METABOLISM; ANEMIA; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL POLARITY; CELL VIABILITY; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; GENE; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; ITPKB GENE; LETHALITY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; GENETICS; KNOCKOUT MOUSE; MORTALITY; PHYSIOLOGY; SEVERITY OF ILLNESS INDEX;

ANEMIA; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HOMEOSTASIS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); SEVERITY OF ILLNESS INDEX;

EID: 84929484174     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-06-583187     Document Type: Article

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